Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 57

1.

Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts.

Iwaki H, Blauwendraat C, Leonard HL, Kim JJ, Liu G, Maple-Grødem J, Corvol JC, Pihlstrøm L, van Nimwegen M, Hutten SJ, Nguyen KH, Rick J, Eberly S, Faghri F, Auinger P, Scott KM, Wijeyekoon R, Van Deerlin VM, Hernandez DG, Gibbs JR; International Parkinson's Disease Genomics Consortium, Chitrala KN, Day-Williams AG, Brice A, Alves G, Noyce AJ, Tysnes OB, Evans JR, Breen DP, Estrada K, Wegel CE, Danjou F, Simon DK, Andreassen O, Ravina B, Toft M, Heutink P, Bloem BR, Weintraub D, Barker RA, Williams-Gray CH, van de Warrenburg BP, Van Hilten JJ, Scherzer CR, Singleton AB, Nalls MA.

Mov Disord. 2019 Sep 10. doi: 10.1002/mds.27845. [Epub ahead of print]

PMID:
31505070
2.

Genetic risk of Parkinson disease and progression:: An analysis of 13 longitudinal cohorts.

Iwaki H, Blauwendraat C, Leonard HL, Liu G, Maple-Grødem J, Corvol JC, Pihlstrøm L, van Nimwegen M, Hutten SJ, Nguyen KH, Rick J, Eberly S, Faghri F, Auinger P, Scott KM, Wijeyekoon R, Van Deerlin VM, Hernandez DG, Day-Williams AG, Brice A, Alves G, Noyce AJ, Tysnes OB, Evans JR, Breen DP, Estrada K, Wegel CE, Danjou F, Simon DK, Ravina B, Toft M, Heutink P, Bloem BR, Weintraub D, Barker RA, Williams-Gray CH, van de Warrenburg BP, Van Hilten JJ, Scherzer CR, Singleton AB, Nalls MA.

Neurol Genet. 2019 Jul 9;5(4):e348. doi: 10.1212/NXG.0000000000000348. eCollection 2019 Aug. Erratum in: Neurol Genet. 2019 Aug 15;5(4):e354.

3.

Lower extremity muscle pathology in myotonic dystrophy type 1 assessed by quantitative MRI.

Heskamp L, van Nimwegen M, Ploegmakers MJ, Bassez G, Deux JF, Cumming SA, Monckton DG, van Engelen BGM, Heerschap A.

Neurology. 2019 Jun 11;92(24):e2803-e2814. doi: 10.1212/WNL.0000000000007648. Epub 2019 May 22.

4.

Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma.

Pfaar O, Bachert C, Kuna P, Panzner P, Džupinová M, Klimek L, van Nimwegen MJ, Boot JD, Yu D, Opstelten DJE, de Kam PJ.

J Allergy Clin Immunol. 2019 Mar;143(3):970-977. doi: 10.1016/j.jaci.2018.11.018. Epub 2018 Nov 30.

5.

Increased surface expression of NOTCH on memory T cells in peripheral blood from patients with asthma.

Tindemans I, Vroman H, Lukkes M, van Nimwegen M, de Bruijn MJW, Li BWS, Kleinjan A, de Boer GM, Tramper-Stranders GA, Kool M, Braunstahl GJ, Hendriks RW.

J Allergy Clin Immunol. 2019 Feb;143(2):769-771.e3. doi: 10.1016/j.jaci.2018.09.012. Epub 2018 Oct 5. No abstract available.

PMID:
30296524
6.

T cells and ILC2s are major effector cells in influenza-induced exacerbation of allergic airway inflammation in mice.

Li BWS, de Bruijn MJW, Lukkes M, van Nimwegen M, Bergen IM, KleinJan A, GeurtsvanKessel CH, Andeweg A, Rimmelzwaan GF, Hendriks RW.

Eur J Immunol. 2019 Jan;49(1):144-156. doi: 10.1002/eji.201747421. Epub 2018 Jun 11.

7.

Fibrocytes are increased in lung and peripheral blood of patients with idiopathic pulmonary fibrosis.

Heukels P, van Hulst JAC, van Nimwegen M, Boorsma CE, Melgert BN, van den Toorn LM, Boomars KAT, Wijsenbeek MS, Hoogsteden H, von der Thüsen JH, Hendriks RW, Kool M, van den Blink B.

Respir Res. 2018 May 10;19(1):90. doi: 10.1186/s12931-018-0798-8.

8.

Increased T-helper 17.1 cells in sarcoidosis mediastinal lymph nodes.

Broos CE, Koth LL, van Nimwegen M, In 't Veen JCCM, Paulissen SMJ, van Hamburg JP, Annema JT, Heller-Baan R, Kleinjan A, Hoogsteden HC, Wijsenbeek MS, Hendriks RW, van den Blink B, Kool M.

Eur Respir J. 2018 Mar 1;51(3). pii: 1701124. doi: 10.1183/13993003.01124-2017. Print 2018 Mar.

9.

A pathophysiological role of PDE3 in allergic airway inflammation.

Beute J, Lukkes M, Koekoek EP, Nastiti H, Ganesh K, de Bruijn MJ, Hockman S, van Nimwegen M, Braunstahl GJ, Boon L, Lambrecht BN, Manganiello VC, Hendriks RW, KleinJan A.

JCI Insight. 2018 Jan 25;3(2). pii: 94888. doi: 10.1172/jci.insight.94888. eCollection 2018 Jan 25.

10.

The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma.

KleinJan A, Tindemans I, Montgomery JE, Lukkes M, de Bruijn MJW, van Nimwegen M, Bergen I, Moellering RE, Hoogsteden HC, Boon L, Amsen D, Hendriks RW.

J Allergy Clin Immunol. 2018 Jul;142(1):76-85.e8. doi: 10.1016/j.jaci.2017.08.042. Epub 2017 Oct 27.

PMID:
29111218
11.

TNF-α-induced protein 3 levels in lung dendritic cells instruct TH2 or TH17 cell differentiation in eosinophilic or neutrophilic asthma.

Vroman H, Bergen IM, van Hulst JAC, van Nimwegen M, van Uden D, Schuijs MJ, Pillai SY, van Loo G, Hammad H, Lambrecht BN, Hendriks RW, Kool M.

J Allergy Clin Immunol. 2018 May;141(5):1620-1633.e12. doi: 10.1016/j.jaci.2017.08.012. Epub 2017 Sep 6.

PMID:
28888782
12.

Depletion of Tumor-Associated Macrophages with a CSF-1R Kinase Inhibitor Enhances Antitumor Immunity and Survival Induced by DC Immunotherapy.

Dammeijer F, Lievense LA, Kaijen-Lambers ME, van Nimwegen M, Bezemer K, Hegmans JP, van Hall T, Hendriks RW, Aerts JG.

Cancer Immunol Res. 2017 Jul;5(7):535-546. doi: 10.1158/2326-6066.CIR-16-0309. Epub 2017 May 23.

13.

Notch signaling in T cells is essential for allergic airway inflammation, but expression of the Notch ligands Jagged 1 and Jagged 2 on dendritic cells is dispensable.

Tindemans I, Lukkes M, de Bruijn MJW, Li BWS, van Nimwegen M, Amsen D, KleinJan A, Hendriks RW.

J Allergy Clin Immunol. 2017 Oct;140(4):1079-1089. doi: 10.1016/j.jaci.2016.11.046. Epub 2017 Jan 19.

PMID:
28111308
14.

Physical therapy and occupational therapy in Parkinson's disease.

Radder DLM, Sturkenboom IH, van Nimwegen M, Keus SH, Bloem BR, de Vries NM.

Int J Neurosci. 2017 Oct;127(10):930-943. doi: 10.1080/00207454.2016.1275617. Epub 2017 Jan 4. Review.

PMID:
28007002
15.

Impaired survival of regulatory T cells in pulmonary sarcoidosis.

Broos CE, van Nimwegen M, Kleinjan A, ten Berge B, Muskens F, in 't Veen JC, Annema JT, Lambrecht BN, Hoogsteden HC, Hendriks RW, Kool M, van den Blink B.

Respir Res. 2015 Sep 16;16:108. doi: 10.1186/s12931-015-0265-8.

16.

Decreased Cytotoxic T-Lymphocyte Antigen 4 Expression on Regulatory T Cells and Th17 Cells in Sarcoidosis: Double Trouble?

Broos CE, van Nimwegen M, In 't Veen JC, Hoogsteden HC, Hendriks RW, van den Blink B, Kool M.

Am J Respir Crit Care Med. 2015 Sep 15;192(6):763-5. doi: 10.1164/rccm.201503-0635LE. No abstract available.

PMID:
26371815
17.

A personalized coaching program increases outdoor activities and physical fitness in sedentary Parkinson patients; a post-hoc analysis of the ParkFit trial.

van der Kolk NM, van Nimwegen M, Speelman AD, Munneke M, Backx FJ, Donders R, Post B, Overeem S, Bloem BR.

Parkinsonism Relat Disord. 2014 Dec;20(12):1442-4. doi: 10.1016/j.parkreldis.2014.10.004. Epub 2014 Oct 12. No abstract available.

PMID:
25455695
18.

BDNF polymorphism associates with decline in set shifting in Parkinson's disease.

van der Kolk NM, Speelman AD, van Nimwegen M, Kessels RP, IntHout J, Hakobjan M, Munneke M, Bloem BR, van de Warrenburg BP.

Neurobiol Aging. 2015 Mar;36(3):1605.e1-6. doi: 10.1016/j.neurobiolaging.2014.08.023. Epub 2014 Aug 27.

PMID:
25444596
19.

Extracellular matrix defects in aneurysmal Fibulin-4 mice predispose to lung emphysema.

Ramnath NW, van de Luijtgaarden KM, van der Pluijm I, van Nimwegen M, van Heijningen PM, Swagemakers SM, van Thiel BS, Ridwan RY, van Vliet N, Vermeij M, Hawinkels LJ, de Munck A, Dzyubachyk O, Meijering E, van der Spek P, Rottier R, Yanagisawa H, Hendriks RW, Kanaar R, Rouwet EV, Kleinjan A, Essers J.

PLoS One. 2014 Sep 25;9(9):e106054. doi: 10.1371/journal.pone.0106054. eCollection 2014.

20.

Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation.

van Miltenburg MH, van Nimwegen MJ, Tijdens I, Lalai R, Kuiper R, Klarenbeek S, Schouten PC, de Vries A, Jonkers J, van de Water B.

Br J Cancer. 2014 May 27;110(11):2747-55. doi: 10.1038/bjc.2014.219. Epub 2014 May 8.

21.

Absence of interleukin-17 receptor a signaling prevents autoimmune inflammation of the joint and leads to a Th2-like phenotype in collagen-induced arthritis.

Corneth OB, Mus AM, Asmawidjaja PS, Klein Wolterink RG, van Nimwegen M, Brem MD, Hofman Y, Hendriks RW, Lubberts E.

Arthritis Rheumatol. 2014 Feb;66(2):340-9. doi: 10.1002/art.38229.

22.

Enforced expression of Gata3 in T cells and group 2 innate lymphoid cells increases susceptibility to allergic airway inflammation in mice.

KleinJan A, Klein Wolterink RG, Levani Y, de Bruijn MJ, Hoogsteden HC, van Nimwegen M, Hendriks RW.

J Immunol. 2014 Feb 15;192(4):1385-94. doi: 10.4049/jimmunol.1301888. Epub 2014 Jan 10.

23.

Granuloma formation in pulmonary sarcoidosis.

Broos CE, van Nimwegen M, Hoogsteden HC, Hendriks RW, Kool M, van den Blink B.

Front Immunol. 2013 Dec 10;4:437. doi: 10.3389/fimmu.2013.00437. Review.

24.

Evaluation of implementation of the ParkFit program: A multifaceted intervention aimed to promote physical activity in patients with Parkinson's disease.

Speelman AD, van Nimwegen M, Bloem BR, Munneke M.

Physiotherapy. 2014 Jun;100(2):134-41. doi: 10.1016/j.physio.2013.05.003. Epub 2013 Aug 21.

PMID:
23972329
25.

Quantifying daily physical activity and determinants in sedentary patients with Parkinson's disease.

Dontje ML, de Greef MH, Speelman AD, van Nimwegen M, Krijnen WP, Stolk RP, Kamsma YP, Bloem BR, Munneke M, van der Schans CP.

Parkinsonism Relat Disord. 2013 Oct;19(10):878-82. doi: 10.1016/j.parkreldis.2013.05.014. Epub 2013 Jun 12.

PMID:
23769178
26.

Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells.

Klein Wolterink RG, Serafini N, van Nimwegen M, Vosshenrich CA, de Bruijn MJ, Fonseca Pereira D, Veiga Fernandes H, Hendriks RW, Di Santo JP.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10240-5. doi: 10.1073/pnas.1217158110. Epub 2013 Jun 3.

27.

Promotion of physical activity and fitness in sedentary patients with Parkinson's disease: randomised controlled trial.

van Nimwegen M, Speelman AD, Overeem S, van de Warrenburg BP, Smulders K, Dontje ML, Borm GF, Backx FJ, Bloem BR, Munneke M; ParkFit Study Group.

BMJ. 2013 Mar 1;346:f576. doi: 10.1136/bmj.f576.

28.

Topical treatment targeting sphingosine-1-phosphate and sphingosine lyase abrogates experimental allergic rhinitis in a murine model.

Kleinjan A, van Nimwegen M, Leman K, Hoogsteden HC, Lambrecht BN.

Allergy. 2013 Feb;68(2):204-12. doi: 10.1111/all.12082. Epub 2012 Dec 18.

PMID:
23253209
29.

Bone mineral density and vitamin D status in Parkinson's disease patients.

van den Bos F, Speelman AD, van Nimwegen M, van der Schouw YT, Backx FJ, Bloem BR, Munneke M, Verhaar HJ.

J Neurol. 2013 Mar;260(3):754-60. doi: 10.1007/s00415-012-6697-x. Epub 2012 Oct 9.

PMID:
23052606
30.

Ursodeoxycholic acid suppresses eosinophilic airway inflammation by inhibiting the function of dendritic cells through the nuclear farnesoid X receptor.

Willart MA, van Nimwegen M, Grefhorst A, Hammad H, Moons L, Hoogsteden HC, Lambrecht BN, Kleinjan A.

Allergy. 2012 Dec;67(12):1501-10. doi: 10.1111/all.12019. Epub 2012 Sep 25.

PMID:
23004356
31.

Involvement of specific executive functions in mobility in Parkinson's disease.

Smulders K, van Nimwegen M, Munneke M, Bloem BR, Kessels RP, Esselink RA.

Parkinsonism Relat Disord. 2013 Jan;19(1):126-8. doi: 10.1016/j.parkreldis.2012.06.010. Epub 2012 Jul 5.

PMID:
22771282
32.

Pulmonary innate lymphoid cells are major producers of IL-5 and IL-13 in murine models of allergic asthma.

Klein Wolterink RG, Kleinjan A, van Nimwegen M, Bergen I, de Bruijn M, Levani Y, Hendriks RW.

Eur J Immunol. 2012 May;42(5):1106-16. doi: 10.1002/eji.201142018.

33.

Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice.

Kil LP, de Bruijn MJ, van Nimwegen M, Corneth OB, van Hamburg JP, Dingjan GM, Thaiss F, Rimmelzwaan GF, Elewaut D, Delsing D, van Loo PF, Hendriks RW.

Blood. 2012 Apr 19;119(16):3744-56. doi: 10.1182/blood-2011-12-397919. Epub 2012 Mar 1.

34.

Cardiovascular responses during a submaximal exercise test in patients with Parkinson's disease.

Speelman AD, Groothuis JT, van Nimwegen M, van der Scheer ES, Borm GF, Bloem BR, Hopman MT, Munneke M.

J Parkinsons Dis. 2012;2(3):241-7. doi: 10.3233/JPD-2012-012111.

PMID:
23938232
35.

Facilitated antigen uptake and timed exposure to TLR ligands dictate the antigen-presenting potential of plasmacytoid DCs.

Kool M, Geurtsvankessel C, Muskens F, Madeira FB, van Nimwegen M, Kuipers H, Thielemans K, Hoogsteden HC, Hammad H, Lambrecht BN.

J Leukoc Biol. 2011 Dec;90(6):1177-90. doi: 10.1189/jlb.0610342. Epub 2011 Sep 20.

PMID:
21934071
36.

How might physical activity benefit patients with Parkinson disease?

Speelman AD, van de Warrenburg BP, van Nimwegen M, Petzinger GM, Munneke M, Bloem BR.

Nat Rev Neurol. 2011 Jul 12;7(9):528-34. doi: 10.1038/nrneurol.2011.107. Review.

PMID:
21750523
37.

Physical inactivity in Parkinson's disease.

van Nimwegen M, Speelman AD, Hofman-van Rossum EJ, Overeem S, Deeg DJ, Borm GF, van der Horst MH, Bloem BR, Munneke M.

J Neurol. 2011 Dec;258(12):2214-21. doi: 10.1007/s00415-011-6097-7. Epub 2011 May 26.

38.

An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma.

Kool M, Willart MA, van Nimwegen M, Bergen I, Pouliot P, Virchow JC, Rogers N, Osorio F, Reis e Sousa C, Hammad H, Lambrecht BN.

Immunity. 2011 Apr 22;34(4):527-40. doi: 10.1016/j.immuni.2011.03.015. Epub 2011 Apr 7. Erratum in: Immunity. 2011 Apr 22;34(4):627. Reis E Sousa, Caetano [corrected to Reis e Sousa, Caetano]..

39.

Monitoring of walking in Parkinson's disease: validation of an ambulatory activity monitor.

Speelman AD, van Nimwegen M, Borm GF, Bloem BR, Munneke M.

Parkinsonism Relat Disord. 2011 Jun;17(5):402-4. doi: 10.1016/j.parkreldis.2011.02.006. Epub 2011 Mar 1. No abstract available.

PMID:
21367643
40.

COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function.

Veltman JD, Lambers ME, van Nimwegen M, Hendriks RW, Hoogsteden HC, Aerts JG, Hegmans JP.

BMC Cancer. 2010 Aug 30;10:464. doi: 10.1186/1471-2407-10-464.

41.

Design and baseline characteristics of the ParkFit study, a randomized controlled trial evaluating the effectiveness of a multifaceted behavioral program to increase physical activity in Parkinson patients.

van Nimwegen M, Speelman AD, Smulders K, Overeem S, Borm GF, Backx FJ, Bloem BR, Munneke M; ParkFit Study Group.

BMC Neurol. 2010 Aug 19;10:70. doi: 10.1186/1471-2377-10-70.

42.

Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma.

Veltman JD, Lambers ME, van Nimwegen M, Hendriks RW, Hoogsteden HC, Hegmans JP, Aerts JG.

Br J Cancer. 2010 Aug 24;103(5):629-41. doi: 10.1038/sj.bjc.6605814. Epub 2010 Jul 27.

43.

Low-dose cyclophosphamide synergizes with dendritic cell-based immunotherapy in antitumor activity.

Veltman JD, Lambers ME, van Nimwegen M, de Jong S, Hendriks RW, Hoogsteden HC, Aerts JG, Hegmans JP.

J Biomed Biotechnol. 2010;2010:798467. doi: 10.1155/2010/798467. Epub 2010 May 23.

44.

United airways: circulating Th2 effector cells in an allergic rhinitis model are responsible for promoting lower airways inflammation.

KleinJan A, Willart M, van Nimwegen M, Leman K, Hoogsteden HC, Hendriks RW, Lambrecht BN.

Clin Exp Allergy. 2010 Mar;40(3):494-504. doi: 10.1111/j.1365-2222.2009.03417.x. Epub 2009 Nov 25.

PMID:
19968652
45.

An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation.

Kool M, van Nimwegen M, Willart MA, Muskens F, Boon L, Smit JJ, Coyle A, Clausen BE, Hoogsteden HC, Lambrecht BN, Hammad H.

J Immunol. 2009 Jul 15;183(2):1074-82. doi: 10.4049/jimmunol.0900471. Epub 2009 Jun 24.

46.

Cholera toxin B suppresses allergic inflammation through induction of secretory IgA.

Smits HH, Gloudemans AK, van Nimwegen M, Willart MA, Soullié T, Muskens F, de Jong EC, Boon L, Pilette C, Johansen FE, Hoogsteden HC, Hammad H, Lambrecht BN.

Mucosal Immunol. 2009 Jul;2(4):331-9. doi: 10.1038/mi.2009.16. Epub 2009 Apr 29.

PMID:
19404246
47.

Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome.

Kool M, Pétrilli V, De Smedt T, Rolaz A, Hammad H, van Nimwegen M, Bergen IM, Castillo R, Lambrecht BN, Tschopp J.

J Immunol. 2008 Sep 15;181(6):3755-9.

48.

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells.

Kool M, Soullié T, van Nimwegen M, Willart MA, Muskens F, Jung S, Hoogsteden HC, Hammad H, Lambrecht BN.

J Exp Med. 2008 Apr 14;205(4):869-82. doi: 10.1084/jem.20071087. Epub 2008 Mar 24.

49.

Solving a mental rotation task in congenital hemiparesis: motor imagery versus visual imagery.

Steenbergen B, van Nimwegen M, Crajé C.

Neuropsychologia. 2007 Nov 5;45(14):3324-8. Epub 2007 Jul 10.

PMID:
17706255
50.

Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection.

Smits HH, Hammad H, van Nimwegen M, Soullie T, Willart MA, Lievers E, Kadouch J, Kool M, Kos-van Oosterhoud J, Deelder AM, Lambrecht BN, Yazdanbakhsh M.

J Allergy Clin Immunol. 2007 Oct;120(4):932-40. Epub 2007 Aug 8.

PMID:
17689595

Supplemental Content

Loading ...
Support Center