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Items: 20


Allele-specific expression and eQTL analysis in mouse adipose tissue.

Hasin-Brumshtein Y, Hormozdiari F, Martin L, van Nas A, Eskin E, Lusis AJ, Drake TA.

BMC Genomics. 2014 Jun 13;15:471. doi: 10.1186/1471-2164-15-471.


Analysis of allele-specific expression in mouse liver by RNA-Seq: a comparison with Cis-eQTL identified using genetic linkage.

Lagarrigue S, Martin L, Hormozdiari F, Roux PF, Pan C, van Nas A, Demeure O, Cantor R, Ghazalpour A, Eskin E, Lusis AJ.

Genetics. 2013 Nov;195(3):1157-66. doi: 10.1534/genetics.113.153882. Epub 2013 Sep 11. Erratum in: Genetics. 2014 Apr;196(4):1359.


The systems genetics resource: a web application to mine global data for complex disease traits.

van Nas A, Pan C, Ingram-Drake LA, Ghazalpour A, Drake TA, Sobel EM, Papp JC, Lusis AJ.

Front Genet. 2013 May 20;4:84. doi: 10.3389/fgene.2013.00084. eCollection 2013.


Genome-wide association mapping of blood cell traits in mice.

Davis RC, van Nas A, Bennett B, Orozco L, Pan C, Rau CD, Eskin E, Lusis AJ.

Mamm Genome. 2013 Apr;24(3-4):105-18. doi: 10.1007/s00335-013-9448-0. Epub 2013 Feb 17.


Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits.

Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, Jentsch JD, Kostem E, Kang HM, Kang EY, Joo JW, Korshunov VA, Laughlin RE, Martin LJ, Ohmen JD, Parks BW, Pellegrini M, Reue K, Smith DJ, Tetradis S, Wang J, Wang Y, Weiss JN, Kirchgessner T, Gargalovic PS, Eskin E, Lusis AJ, LeBoeuf RC.

Mamm Genome. 2012 Oct;23(9-10):680-92. doi: 10.1007/s00335-012-9411-5. Epub 2012 Aug 15. Review.


Increasing association mapping power and resolution in mouse genetic studies through the use of meta-analysis for structured populations.

Furlotte NA, Kang EY, Van Nas A, Farber CR, Lusis AJ, Eskin E.

Genetics. 2012 Jul;191(3):959-67. doi: 10.1534/genetics.112.140277. Epub 2012 Apr 13.


Systems genetics of susceptibility to obesity-induced diabetes in mice.

Davis RC, van Nas A, Castellani LW, Zhao Y, Zhou Z, Wen P, Yu S, Qi H, Rosales M, Schadt EE, Broman KW, Péterfy M, Lusis AJ.

Physiol Genomics. 2012 Jan 18;44(1):1-13. doi: 10.1152/physiolgenomics.00003.2011. Epub 2011 Oct 18.


An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.

Hsu YH, Zillikens MC, Wilson SG, Farber CR, Demissie S, Soranzo N, Bianchi EN, Grundberg E, Liang L, Richards JB, Estrada K, Zhou Y, van Nas A, Moffatt MF, Zhai G, Hofman A, van Meurs JB, Pols HA, Price RI, Nilsson O, Pastinen T, Cupples LA, Lusis AJ, Schadt EE, Ferrari S, Uitterlinden AG, Rivadeneira F, Spector TD, Karasik D, Kiel DP.

PLoS Genet. 2010 Jun 10;6(6):e1000977. doi: 10.1371/journal.pgen.1000977.


Expression quantitative trait loci: replication, tissue- and sex-specificity in mice.

van Nas A, Ingram-Drake L, Sinsheimer JS, Wang SS, Schadt EE, Drake T, Lusis AJ.

Genetics. 2010 Jul;185(3):1059-68. doi: 10.1534/genetics.110.116087. Epub 2010 May 3.


Systems biology asks new questions about sex differences.

Arnold AP, van Nas A, Lusis AJ.

Trends Endocrinol Metab. 2009 Dec;20(10):471-6. doi: 10.1016/j.tem.2009.06.007. Epub 2009 Sep 23.


Copy number variation influences gene expression and metabolic traits in mice.

Orozco LD, Cokus SJ, Ghazalpour A, Ingram-Drake L, Wang S, van Nas A, Che N, Araujo JA, Pellegrini M, Lusis AJ.

Hum Mol Genet. 2009 Nov 1;18(21):4118-29. doi: 10.1093/hmg/ddp360. Epub 2009 Jul 31.


Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks.

Yang X, Deignan JL, Qi H, Zhu J, Qian S, Zhong J, Torosyan G, Majid S, Falkard B, Kleinhanz RR, Karlsson J, Castellani LW, Mumick S, Wang K, Xie T, Coon M, Zhang C, Estrada-Smith D, Farber CR, Wang SS, van Nas A, Ghazalpour A, Zhang B, Macneil DJ, Lamb JR, Dipple KM, Reitman ML, Mehrabian M, Lum PY, Schadt EE, Lusis AJ, Drake TA.

Nat Genet. 2009 Apr;41(4):415-23. doi: 10.1038/ng.325. Epub 2009 Mar 8.


Maternal low-protein diet or hypercholesterolemia reduces circulating essential amino acids and leads to intrauterine growth restriction.

Bhasin KK, van Nas A, Martin LJ, Davis RC, Devaskar SU, Lusis AJ.

Diabetes. 2009 Mar;58(3):559-66. doi: 10.2337/db07-1530. Epub 2008 Dec 10.


Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks.

van Nas A, Guhathakurta D, Wang SS, Yehya N, Horvath S, Zhang B, Ingram-Drake L, Chaudhuri G, Schadt EE, Drake TA, Arnold AP, Lusis AJ.

Endocrinology. 2009 Mar;150(3):1235-49. doi: 10.1210/en.2008-0563. Epub 2008 Oct 30.


An integrative genetics approach to identify candidate genes regulating BMD: combining linkage, gene expression, and association.

Farber CR, van Nas A, Ghazalpour A, Aten JE, Doss S, Sos B, Schadt EE, Ingram-Drake L, Davis RC, Horvath S, Smith DJ, Drake TA, Lusis AJ.

J Bone Miner Res. 2009 Jan;24(1):105-16. doi: 10.1359/jbmr.080908.


Mapping the genetic architecture of gene expression in human liver.

Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, Derry J, Storey JD, Avila-Campillo I, Kruger MJ, Johnson JM, Rohl CA, van Nas A, Mehrabian M, Drake TA, Lusis AJ, Smith RC, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich R.

PLoS Biol. 2008 May 6;6(5):e107. doi: 10.1371/journal.pbio.0060107.


Dosage compensation is less effective in birds than in mammals.

Itoh Y, Melamed E, Yang X, Kampf K, Wang S, Yehya N, Van Nas A, Replogle K, Band MR, Clayton DF, Schadt EE, Lusis AJ, Arnold AP.

J Biol. 2007;6(1):2. doi: 10.1186/jbiol53.


A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background.

Davis RC, Schadt EE, Smith DJ, Hsieh EW, Cervino AC, van Nas A, Rosales M, Doss S, Meng H, Allayee H, Lusis AJ.

Genomics. 2005 Sep;86(3):259-70.


Quantitative trait loci for apolipoprotein B, cholesterol, and triglycerides in familial combined hyperlipidemia pedigrees.

Cantor RM, de Bruin T, Kono N, Napier S, van Nas A, Allayee H, Lusis AJ.

Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1935-41. Epub 2004 Aug 12.


Thematic review series: The pathogenesis of atherosclerosis. Toward a biological network for atherosclerosis.

Ghazalpour A, Doss S, Yang X, Aten J, Toomey EM, Van Nas A, Wang S, Drake TA, Lusis AJ.

J Lipid Res. 2004 Oct;45(10):1793-805. Epub 2004 Aug 1. Review.

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