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Items: 43

1.

Patient-derived tumor organoids for prediction of cancer treatment response.

Nagle PW, Plukker JTM, Muijs CT, van Luijk P, Coppes RP.

Semin Cancer Biol. 2018 Jun 30. pii: S1044-579X(18)30046-4. doi: 10.1016/j.semcancer.2018.06.005. [Epub ahead of print] Review.

2.

A new method to assess pulmonary changes using 18F-fluoro-2-deoxyglucose positron emission tomography for lung cancer patients following radiotherapy.

Abravan A, Knudtsen IS, Eide HA, Løndalen AM, Helland Å, van Luijk P, Malinen E.

Acta Oncol. 2017 Nov;56(11):1597-1603. doi: 10.1080/0284186X.2017.1349336. Epub 2017 Aug 29.

PMID:
28849707
3.

Understanding mechanisms yields novel approaches to reduce radiotherapy-related xerostomia.

van Luijk P, Langendijk JA, Coppes RP.

Ann Transl Med. 2017 Feb;5(3):63. doi: 10.21037/atm.2017.02.02. No abstract available.

4.

Decreasing Irradiated Rat Lung Volume Changes Dose-Limiting Toxicity From Early to Late Effects.

van der Veen SJ, Faber H, Ghobadi G, Brandenburg S, Langendijk JA, Coppes RP, van Luijk P.

Int J Radiat Oncol Biol Phys. 2016 Jan 1;94(1):163-171. doi: 10.1016/j.ijrobp.2015.09.034. Epub 2015 Sep 28.

PMID:
26700710
5.

Sparing the region of the salivary gland containing stem cells preserves saliva production after radiotherapy for head and neck cancer.

van Luijk P, Pringle S, Deasy JO, Moiseenko VV, Faber H, Hovan A, Baanstra M, van der Laan HP, Kierkels RG, van der Schaaf A, Witjes MJ, Schippers JM, Brandenburg S, Langendijk JA, Wu J, Coppes RP.

Sci Transl Med. 2015 Sep 16;7(305):305ra147. doi: 10.1126/scitranslmed.aac4441.

6.

A new CT-based method to quantify radiation-induced lung damage in patients.

Ghobadi G, Wiegman EM, Langendijk JA, Widder J, Coppes RP, van Luijk P.

Radiother Oncol. 2015 Oct;117(1):4-8. doi: 10.1016/j.radonc.2015.07.017. Epub 2015 Aug 4.

7.

Is cardiac toxicity a relevant issue in the radiation treatment of esophageal cancer?

Beukema JC, van Luijk P, Widder J, Langendijk JA, Muijs CT.

Radiother Oncol. 2015 Jan;114(1):85-90. doi: 10.1016/j.radonc.2014.11.037. Epub 2014 Dec 30. Review.

PMID:
25554226
8.

ACE inhibition attenuates radiation-induced cardiopulmonary damage.

van der Veen SJ, Ghobadi G, de Boer RA, Faber H, Cannon MV, Nagle PW, Brandenburg S, Langendijk JA, van Luijk P, Coppes RP.

Radiother Oncol. 2015 Jan;114(1):96-103. doi: 10.1016/j.radonc.2014.11.017. Epub 2014 Nov 25.

9.

Current ideas to reduce or salvage radiation damage to salivary glands.

Vissink A, van Luijk P, Langendijk JA, Coppes RP.

Oral Dis. 2015 Jan;21(1):e1-10. doi: 10.1111/odi.12222. Epub 2014 Feb 28. Review.

PMID:
24581290
10.

The QUANTEC criteria for parotid gland dose and their efficacy to prevent moderate to severe patient-rated xerostomia.

Beetz I, Steenbakkers RJ, Chouvalova O, Leemans CR, Doornaert P, van der Laan BF, Christianen ME, Vissink A, Bijl HP, van Luijk P, Langendijk JA.

Acta Oncol. 2014 May;53(5):597-604. doi: 10.3109/0284186X.2013.831186. Epub 2013 Sep 2.

PMID:
23998646
11.

Biological considerations when comparing proton therapy with photon therapy.

Paganetti H, van Luijk P.

Semin Radiat Oncol. 2013 Apr;23(2):77-87. doi: 10.1016/j.semradonc.2012.11.002.

PMID:
23473684
12.

Physiological interaction of heart and lung in thoracic irradiation.

Ghobadi G, van der Veen S, Bartelds B, de Boer RA, Dickinson MG, de Jong JR, Faber H, Niemantsverdriet M, Brandenburg S, Berger RM, Langendijk JA, Coppes RP, van Luijk P.

Int J Radiat Oncol Biol Phys. 2012 Dec 1;84(5):e639-46. doi: 10.1016/j.ijrobp.2012.07.2362. Epub 2012 Sep 11.

13.

Biological mechanisms of normal tissue damage: importance for the design of NTCP models.

Trott KR, Doerr W, Facoetti A, Hopewell J, Langendijk J, van Luijk P, Ottolenghi A, Smyth V.

Radiother Oncol. 2012 Oct;105(1):79-85. doi: 10.1016/j.radonc.2012.05.008. Epub 2012 Jun 29. Review.

PMID:
22748390
14.

NTCP models for patient-rated xerostomia and sticky saliva after treatment with intensity modulated radiotherapy for head and neck cancer: the role of dosimetric and clinical factors.

Beetz I, Schilstra C, van der Schaaf A, van den Heuvel ER, Doornaert P, van Luijk P, Vissink A, van der Laan BF, Leemans CR, Bijl HP, Christianen ME, Steenbakkers RJ, Langendijk JA.

Radiother Oncol. 2012 Oct;105(1):101-6. doi: 10.1016/j.radonc.2012.03.004. Epub 2012 Apr 18.

15.

Multivariate modeling of complications with data driven variable selection: guarding against overfitting and effects of data set size.

van der Schaaf A, Xu CJ, van Luijk P, Van't Veld AA, Langendijk JA, Schilstra C.

Radiother Oncol. 2012 Oct;105(1):115-21. doi: 10.1016/j.radonc.2011.12.006. Epub 2012 Jan 20.

PMID:
22264894
16.

High and low LET radiation differentially induce normal tissue damage signals.

Niemantsverdriet M, van Goethem MJ, Bron R, Hogewerf W, Brandenburg S, Langendijk JA, van Luijk P, Coppes RP.

Int J Radiat Oncol Biol Phys. 2012 Jul 15;83(4):1291-7. doi: 10.1016/j.ijrobp.2011.09.057. Epub 2012 Jan 13.

17.

Lung irradiation induces pulmonary vascular remodelling resembling pulmonary arterial hypertension.

Ghobadi G, Bartelds B, van der Veen SJ, Dickinson MG, Brandenburg S, Berger RM, Langendijk JA, Coppes RP, van Luijk P.

Thorax. 2012 Apr;67(4):334-41. doi: 10.1136/thoraxjnl-2011-200346. Epub 2011 Dec 26.

PMID:
22201162
18.

External validation of three dimensional conformal radiotherapy based NTCP models for patient-rated xerostomia and sticky saliva among patients treated with intensity modulated radiotherapy.

Beetz I, Schilstra C, van Luijk P, Christianen ME, Doornaert P, Bijl HP, Chouvalova O, van den Heuvel ER, Steenbakkers RJ, Langendijk JA.

Radiother Oncol. 2012 Oct;105(1):94-100. doi: 10.1016/j.radonc.2011.11.006. Epub 2011 Dec 12.

PMID:
22169766
19.

Volume-dependent expression of in-field and out-of-field effects in the proton-irradiated rat lung.

Coppes RP, Muijs CT, Faber H, Gross S, Schippers JM, Brandenburg S, Langendijk JA, van Luijk P.

Int J Radiat Oncol Biol Phys. 2011 Sep 1;81(1):262-9. doi: 10.1016/j.ijrobp.2011.03.021. Epub 2011 May 24.

PMID:
21605947
20.

Development of a facility for high-precision irradiation of cells with carbon ions.

van Goethem MJ, Niemantsverdriet M, Brandenburg S, Langendijk JA, Coppes RP, van Luijk P.

Med Phys. 2011 Jan;38(1):256-63.

PMID:
21361194
21.

Recurrent scoliosis one year after surgical correction.

van Luijk PJ, de Nies F.

Eur Spine J. 2011 Jul;20 Suppl 2:S193-4. doi: 10.1007/s00586-010-1536-1. Epub 2010 Jul 31.

22.

Quantifying local radiation-induced lung damage from computed tomography.

Ghobadi G, Hogeweg LE, Faber H, Tukker WG, Schippers JM, Brandenburg S, Langendijk JA, Coppes RP, van Luijk P.

Int J Radiat Oncol Biol Phys. 2010 Feb 1;76(2):548-56. doi: 10.1016/j.ijrobp.2009.08.058.

PMID:
20117290
23.

Bath and shower effects in the rat parotid gland explain increased relative risk of parotid gland dysfunction after intensity-modulated radiotherapy.

van Luijk P, Faber H, Schippers JM, Brandenburg S, Langendijk JA, Meertens H, Coppes RP.

Int J Radiat Oncol Biol Phys. 2009 Jul 15;74(4):1002-5. doi: 10.1016/j.ijrobp.2009.03.039.

PMID:
19545785
24.
25.

The impact of heart irradiation on dose-volume effects in the rat lung.

van Luijk P, Faber H, Meertens H, Schippers JM, Langendijk JA, Brandenburg S, Kampinga HH, Coppes RP.

Int J Radiat Oncol Biol Phys. 2007 Oct 1;69(2):552-9.

PMID:
17869668
26.

Protection of salivary function by concomitant pilocarpine during radiotherapy: a double-blind, randomized, placebo-controlled study.

Burlage FR, Roesink JM, Kampinga HH, Coppes RP, Terhaard C, Langendijk JA, van Luijk P, Stokman MA, Vissink A.

Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):14-22. Epub 2007 Sep 14.

PMID:
17869018
27.

Changes in expression of injury after irradiation of increasing volumes in rat lung.

Novakova-Jiresova A, van Luijk P, van Goor H, Kampinga HH, Coppes RP.

Int J Radiat Oncol Biol Phys. 2007 Apr 1;67(5):1510-8.

PMID:
17394947
28.

Relation between radiation-induced whole lung functional loss and regional structural changes in partial irradiated rat lung.

van Luijk P, Novakova-Jiresova A, Faber H, Steneker MN, Kampinga HH, Meertens H, Coppes RP.

Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1495-502.

PMID:
16580500
29.

Influence of adjacent low-dose fields on tolerance to high doses of protons in rat cervical spinal cord.

Bijl HP, van Luijk P, Coppes RP, Schippers JM, Konings AW, van der Kogel AJ.

Int J Radiat Oncol Biol Phys. 2006 Mar 15;64(4):1204-10.

PMID:
16504760
30.

Radiation damage to the heart enhances early radiation-induced lung function loss.

van Luijk P, Novakova-Jiresova A, Faber H, Schippers JM, Kampinga HH, Meertens H, Coppes RP.

Cancer Res. 2005 Aug 1;65(15):6509-11.

31.

Volume effects and region-dependent radiosensitivity of the parotid gland.

Konings AW, Cotteleer F, Faber H, van Luijk P, Meertens H, Coppes RP.

Int J Radiat Oncol Biol Phys. 2005 Jul 15;62(4):1090-5.

PMID:
15990013
32.

Pulmonary radiation injury: identification of risk factors associated with regional hypersensitivity.

Novakova-Jiresova A, van Luijk P, van Goor H, Kampinga HH, Coppes RP.

Cancer Res. 2005 May 1;65(9):3568-76.

33.

Data on dose-volume effects in the rat spinal cord do not support existing NTCP models.

van Luijk P, Bijl HP, Konings AW, van der Kogel AJ, Schippers JM.

Int J Radiat Oncol Biol Phys. 2005 Mar 1;61(3):892-900.

PMID:
15708272
34.

Regional differences in radiosensitivity across the rat cervical spinal cord.

Bijl HP, van Luijk P, Coppes RP, Schippers JM, Konings AW, van Der Kogel AJ.

Int J Radiat Oncol Biol Phys. 2005 Feb 1;61(2):543-51.

PMID:
15667978
35.

Unexpected changes of rat cervical spinal cord tolerance caused by inhomogeneous dose distributions.

Bijl HP, van Luijk P, Coppes RP, Schippers JM, Konings AW, van der Kogel AJ.

Int J Radiat Oncol Biol Phys. 2003 Sep 1;57(1):274-81.

PMID:
12909243
36.

Estimation of parameters of dose-volume models and their confidence limits.

van Luijk P, Delvigne TC, Schilstra C, Schippers JM.

Phys Med Biol. 2003 Jul 7;48(13):1863-84.

PMID:
12884921
37.

Dose-volume effects in the rat cervical spinal cord after proton irradiation.

Bijl HP, van Luijk P, Coppes RP, Schippers JM, Konings AW, van der Kogel AJ.

Int J Radiat Oncol Biol Phys. 2002 Jan 1;52(1):205-11.

PMID:
11777640
38.

Techniques for precision irradiation of the lateral half of the rat cervical spinal cord using 150 MeV protons [corrected].

van Luijk P, Bijl HP, Coppes RP, van der Kogel AJ, Konings AW, Pikkemaat JA, Schippers JM.

Phys Med Biol. 2001 Nov;46(11):2857-71.

PMID:
11720351
39.

Detector line spread functions determined analytically by transport of Compton recoil electrons.

van't Veld AA, van Luijk P, Praamstra F, van der Hulst PC.

Med Phys. 2001 May;28(5):738-51.

PMID:
11393468
40.

Collimator scatter and 2D dosimetry in small proton beams.

van Luijk P, van t' Veld AA, Zelle HD, Schippers JM.

Phys Med Biol. 2001 Mar;46(3):653-70.

PMID:
11277215
41.

Performance of a fluorescent screen and CCD camera as a two-dimensional dosimetry system for dynamic treatment techniques.

Boon SN, van Luijk P, Böhringer T, Coray A, Lomax A, Pedroni E, Schaffner B, Schippers JM.

Med Phys. 2000 Oct;27(10):2198-208.

PMID:
11099186
42.

Slit x-ray beam primary dose profiles determined by analytical transport of Compton recoil electrons.

van't Veld AA, van Luijk P, Praamstra F, van der Hulst PC.

Med Phys. 2000 May;27(5):923-34.

PMID:
10841395
43.

Fast 2D phantom dosimetry for scanning proton beams.

Boon SN, van Luijk P, Schippers JM, Meertens H, Denis JM, Vynckier S, Medin J, Grusell E.

Med Phys. 1998 Apr;25(4):464-75.

PMID:
9571612

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