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Items: 1 to 50 of 61

1.

Optimising SME Potential in Modern Healthcare Systems: Challenges, Opportunities and Policy Recommendations.

Horgan D, van Kranen HJ, Morré SA.

Public Health Genomics. 2018;21(1-2):1-17. doi: 10.1159/000492809. Epub 2018 Aug 24. Review.

2.

MECP2 variation in Rett syndrome-An overview of current coverage of genetic and phenotype data within existing databases.

Townend GS, Ehrhart F, van Kranen HJ, Wilkinson M, Jacobsen A, Roos M, Willighagen EL, van Enckevort D, Evelo CT, Curfs LMG.

Hum Mutat. 2018 Jul;39(7):914-924. doi: 10.1002/humu.23542. Epub 2018 May 21.

3.

Circulating concentrations of vitamin D in relation to pancreatic cancer risk in European populations.

van Duijnhoven FJB, Jenab M, Hveem K, Siersema PD, Fedirko V, Duell EJ, Kampman E, Halfweeg A, van Kranen HJ, van den Ouweland JMW, Weiderpass E, Murphy N, Langhammer A, Ness-Jensen E, Olsen A, Tjønneland A, Overvad K, Cadeau C, Kvaskoff M, Boutron-Ruault MC, Katzke VA, Kühn T, Boeing H, Trichopoulou A, Kotanidou A, Kritikou M, Palli D, Agnoli C, Tumino R, Panico S, Matullo G, Peeters P, Brustad M, Olsen KS, Lasheras C, Obón-Santacana M, Sánchez MJ, Dorronsoro M, Chirlaque MD, Barricarte A, Manjer J, Almquist M, Renström F, Ye W, Wareham N, Khaw KT, Bradbury KE, Freisling H, Aune D, Norat T, Riboli E, Bueno-de-Mesquita HBA.

Int J Cancer. 2018 Mar 15;142(6):1189-1201. doi: 10.1002/ijc.31146. Epub 2017 Nov 22.

4.

Policy Making in Newborn Screening Needs a Structured and Transparent Approach.

Jansen ME, Lister KJ, van Kranen HJ, Cornel MC.

Front Public Health. 2017 Mar 21;5:53. doi: 10.3389/fpubh.2017.00053. eCollection 2017. Review.

5.

The impact of personalized medicine of Type 2 diabetes mellitus in the global health context.

Thomas PPM, Alshehri SM, van Kranen HJ, Ambrosino E.

Per Med. 2016 Jul;13(4):381-393. doi: 10.2217/pme-2016-0029. Epub 2016 Jun 22.

PMID:
29749811
6.

Specific polymorphisms in the vitamin D metabolism pathway are not associated with susceptibility to Chlamydia trachomatis infection in humans.

Lanjouw E, Branković I, Pleijster J, Spaargaren J, Hoebe CJ, van Kranen HJ, Ouburg S, Morré SA.

Pathog Dis. 2016 Apr;74(3). pii: ftw010. doi: 10.1093/femspd/ftw010. Epub 2016 Feb 10.

7.

Preferences for genetic testing for colorectal cancer within a population-based screening program: a discrete choice experiment.

Veldwijk J, Lambooij MS, Kallenberg FG, van Kranen HJ, Bredenoord AL, Dekker E, Smit HA, de Wit GA.

Eur J Hum Genet. 2016 Mar;24(3):361-6. doi: 10.1038/ejhg.2015.117. Epub 2015 Jun 3.

8.

Rett Syndrome as a Rare Disease: A European Perspective.

Townend GS, van Kranen HJ, van der Stel R, van den Berg M, Smeets E, van Waardenburg D, Curfs LM.

Public Health Genomics. 2015;18(4):233-6. doi: 10.1159/000381139. Epub 2015 Apr 14. No abstract available.

PMID:
25895605
9.

Dietary fat intake and development of specific breast cancer subtypes.

Sieri S, Chiodini P, Agnoli C, Pala V, Berrino F, Trichopoulou A, Benetou V, Vasilopoulou E, Sánchez MJ, Chirlaque MD, Amiano P, Quirós JR, Ardanaz E, Buckland G, Masala G, Panico S, Grioni S, Sacerdote C, Tumino R, Boutron-Ruault MC, Clavel-Chapelon F, Fagherazzi G, Peeters PH, van Gils CH, Bueno-de-Mesquita HB, van Kranen HJ, Key TJ, Travis RC, Khaw KT, Wareham NJ, Kaaks R, Lukanova A, Boeing H, Schütze M, Sonestedt E, Wirfält E, Sund M, Andersson A, Chajes V, Rinaldi S, Romieu I, Weiderpass E, Skeie G, Dagrun E, Tjønneland A, Halkjær J, Overvard K, Merritt MA, Cox D, Riboli E, Krogh V.

J Natl Cancer Inst. 2014 Apr 9;106(5). pii: dju068. doi: 10.1093/jnci/dju068.

PMID:
24718872
10.

Smoking and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition.

Rohrmann S, Linseisen J, Allen N, Bueno-de-Mesquita HB, Johnsen NF, Tjønneland A, Overvad K, Kaaks R, Teucher B, Boeing H, Pischon T, Lagiou P, Trichopoulou A, Trichopoulos D, Palli D, Krogh V, Tumino R, Ricceri F, Argüelles Suárez MV, Agudo A, Sánchez MJ, Chirlaque MD, Barricarte A, Larrañaga N, Boshuizen H, van Kranen HJ, Stattin P, Johansson M, Bjartell A, Ulmert D, Khaw KT, Wareham NJ, Ferrari P, Romieux I, Gunter MJ, Riboli E, Key TJ.

Br J Cancer. 2013 Feb 19;108(3):708-14. doi: 10.1038/bjc.2012.520. Epub 2012 Nov 20.

11.

Contribution of bi-allelic germline MUTYH mutations to early-onset and familial colorectal cancer and to low number of adenomatous polyps: case-series and literature review.

Knopperts AP, Nielsen M, Niessen RC, Tops CM, Jorritsma B, Varkevisser J, Wijnen J, Siezen CL, Heine-Bröring RC, van Kranen HJ, Vos YJ, Westers H, Kampman E, Sijmons RH, Hes FJ.

Fam Cancer. 2013 Mar;12(1):43-50. doi: 10.1007/s10689-012-9570-2. Review.

PMID:
23007840
12.

Rapamycin impairs UV induction of mutant-p53 overexpressing cell clusters without affecting tumor onset.

Voskamp P, Bodmann CA, Rebel HG, Koehl GE, Tensen CP, Bouwes Bavinck JN, El Ghalbzouri A, Van Kranen HJ, Willemze R, Geissler EK, De Gruijl FR.

Int J Cancer. 2012 Sep 15;131(6):1267-76. doi: 10.1002/ijc.27391. Epub 2012 Jan 27.

13.

Hepatocellular carcinoma risk factors and disease burden in a European cohort: a nested case-control study.

Trichopoulos D, Bamia C, Lagiou P, Fedirko V, Trepo E, Jenab M, Pischon T, Nöthlings U, Overved K, Tjønneland A, Outzen M, Clavel-Chapelon F, Kaaks R, Lukanova A, Boeing H, Aleksandrova K, Benetou V, Zylis D, Palli D, Pala V, Panico S, Tumino R, Sacerdote C, Bueno-De-Mesquita HB, Van Kranen HJ, Peeters PH, Lund E, Quirós JR, González CA, Sanchez Perez MJ, Navarro C, Dorronsoro M, Barricarte A, Lindkvist B, Regnér S, Werner M, Hallmans G, Khaw KT, Wareham N, Key T, Romieu I, Chuang SC, Murphy N, Boffetta P, Trichopoulou A, Riboli E.

J Natl Cancer Inst. 2011 Nov 16;103(22):1686-95. doi: 10.1093/jnci/djr395. Epub 2011 Oct 21.

14.

Endogenous sex steroids and risk of cervical carcinoma: results from the EPIC study.

Rinaldi S, Plummer M, Biessy C, Castellsagué X, Overvad K, Krüger Kjær S, Tjønneland A, Clavel-Chapelon F, Chabbert-Buffet N, Mesrine S, Lukanova A, Kaaks R, Weikert C, Boeing H, Trichopoulou A, Lagiou P, Trichopoulos D, Palli D, Agnoli C, Tumino R, Vineis P, Panico S, Bueno-de-Mesquita B, van Kranen HJ, Peeters PH, Bakken K, Lund E, Gram IT, Rodríguez L, Bosch FX, Sánchez MJ, Dorronsoro M, Navarro C, Gurrea AB, Kjellberg L, Dillner J, Manjer J, Butt S, Khaw KT, Wareham N, Allen NE, Travis R, Romieu I, Ferrari P, Riboli E, Franceschi S.

Cancer Epidemiol Biomarkers Prev. 2011 Dec;20(12):2532-40. doi: 10.1158/1055-9965.EPI-11-0753. Epub 2011 Oct 12.

15.

Costs and health effects of adding functional foods containing phytosterols/-stanols to statin therapy in the prevention of cardiovascular disease.

Eussen SR, Feenstra TL, Toxopeus IB, Hoekstra J, Klungel OH, Verhagen H, van Kranen HJ, Rompelberg CJ.

Eur J Pharmacol. 2011 Sep;668 Suppl 1:S91-100. doi: 10.1016/j.ejphar.2011.05.081. Epub 2011 Jul 27. Review.

PMID:
21816151
16.

Functional foods and dietary supplements: products at the interface between pharma and nutrition.

Eussen SR, Verhagen H, Klungel OH, Garssen J, van Loveren H, van Kranen HJ, Rompelberg CJ.

Eur J Pharmacol. 2011 Sep;668 Suppl 1:S2-9. doi: 10.1016/j.ejphar.2011.07.008. Epub 2011 Jul 27. Review.

PMID:
21816140
17.

Influence of the use of functional foods enriched with phytosterols/-stanols on adherence to statin therapy.

Eussen SR, Bouvy ML, Rompelberg CJ, van der Elst ME, Garssen J, Oosterveld MH, de Boer A, de Gier JJ, van Kranen HJ, Klungel OH.

Pharmacoepidemiol Drug Saf. 2011 Aug;20(8):830-7. doi: 10.1002/pds.2168. Epub 2011 Jun 7.

PMID:
21648012
18.

Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).

Campa D, Hüsing A, Chang-Claude J, Dostal L, Boeing H, Kröger J, Tjønneland A, Roswall N, Overvad K, Dahm CC, Rodríguez L, Sala N, Pérez MJ, Larrañaga N, Chirlaque MD, Ardanaz E, Khaw KT, Wareham N, Allen NE, Travis RC, Trichopoulou A, Naska A, Bamia C, Palli D, Sieri S, Tumino R, Sacerdote C, van Kranen HJ, Bas Bueno-de-Mesquita H, Stattin P, Johansson M, Chajes V, Rinaldi S, Romieu I, Siddiq A, Norat T, Riboli E, Kaaks R, Canzian F.

Eur J Cancer. 2011 Feb;47(3):420-7. doi: 10.1016/j.ejca.2010.09.029. Epub 2010 Oct 19.

PMID:
20965718
19.

Planning the human variome project: the Spain report.

Kaput J, Cotton RG, Hardman L, Watson M, Al Aqeel AI, Al-Aama JY, Al-Mulla F, Alonso S, Aretz S, Auerbach AD, Bapat B, Bernstein IT, Bhak J, Bleoo SL, Blöcker H, Brenner SE, Burn J, Bustamante M, Calzone R, Cambon-Thomsen A, Cargill M, Carrera P, Cavedon L, Cho YS, Chung YJ, Claustres M, Cutting G, Dalgleish R, den Dunnen JT, Díaz C, Dobrowolski S, dos Santos MR, Ekong R, Flanagan SB, Flicek P, Furukawa Y, Genuardi M, Ghang H, Golubenko MV, Greenblatt MS, Hamosh A, Hancock JM, Hardison R, Harrison TM, Hoffmann R, Horaitis R, Howard HJ, Barash CI, Izagirre N, Jung J, Kojima T, Laradi S, Lee YS, Lee JY, Gil-da-Silva-Lopes VL, Macrae FA, Maglott D, Marafie MJ, Marsh SG, Matsubara Y, Messiaen LM, Möslein G, Netea MG, Norton ML, Oefner PJ, Oetting WS, O'Leary JC, de Ramirez AM, Paalman MH, Parboosingh J, Patrinos GP, Perozzi G, Phillips IR, Povey S, Prasad S, Qi M, Quin DJ, Ramesar RS, Richards CS, Savige J, Scheible DG, Scott RJ, Seminara D, Shephard EA, Sijmons RH, Smith TD, Sobrido MJ, Tanaka T, Tavtigian SV, Taylor GR, Teague J, Töpel T, Ullman-Cullere M, Utsunomiya J, van Kranen HJ, Vihinen M, Webb E, Weber TK, Yeager M, Yeom YI, Yim SH, Yoo HS; Contributors to the Human Variome Project Planning Meeting.

Hum Mutat. 2009 Apr;30(4):496-510. doi: 10.1002/humu.20972.

20.

Estimated number of new cancer cases attributable to infection in the Netherlands in 2003.

van Lier EA, van Kranen HJ, van Vliet JA, Rahamat-Langendoen JC.

Cancer Lett. 2008 Dec 18;272(2):226-31. doi: 10.1016/j.canlet.2008.07.007. Epub 2008 Aug 26.

PMID:
18752887
21.

Opposing associations of serum n-3 and n-6 polyunsaturated fatty acids with colorectal adenoma risk: an endoscopy-based case-control study.

Pot GK, Geelen A, van Heijningen EM, Siezen CL, van Kranen HJ, Kampman E.

Int J Cancer. 2008 Oct 15;123(8):1974-7. doi: 10.1002/ijc.23729.

22.

Comparative gene expression profiling in two congenic mouse strains following Bordetella pertussis infection.

Banus S, Vandebriel RJ, Pennings JL, Gremmer ER, Wester PW, van Kranen HJ, Breit TM, Demant P, Mooi FR, Hoebee B, Kimman TG.

BMC Microbiol. 2007 Oct 12;7:88.

23.

[Folic acid fortification: prevention as well as promotion of cancer].

Kloosterman J, de Jong N, Rompelberg CJ, van Kranen HJ, Kampman E, Ocké MC.

Ned Tijdschr Geneeskd. 2006 Jul 1;150(26):1443-8. Review. Dutch.

PMID:
16875264
24.

Host genetics of Bordetella pertussis infection in mice: significance of Toll-like receptor 4 in genetic susceptibility and pathobiology.

Banus HA, Vandebriel RJ, de Ruiter H, Dormans JA, Nagelkerke NJ, Mooi FR, Hoebee B, van Kranen HJ, Kimman TG.

Infect Immun. 2006 May;74(5):2596-605.

25.

Induction of nevi and skin tumors in Ink4a/Arf Xpa knockout mice by neonatal, intermittent, or chronic UVB exposures.

van Schanke A, van Venrooij GM, Jongsma MJ, Banus HA, Mullenders LH, van Kranen HJ, de Gruijl FR.

Cancer Res. 2006 Mar 1;66(5):2608-15.

26.

Polymorphisms in the genes involved in the arachidonic acid-pathway, fish consumption and the risk of colorectal cancer.

Siezen CL, Bueno-de-Mesquita HB, Peeters PH, Kram NR, van Doeselaar M, van Kranen HJ.

Int J Cancer. 2006 Jul 15;119(2):297-303.

27.

Protective effect of nonsteroidal anti-inflammatory drugs on colorectal adenomas is modified by a polymorphism in peroxisome proliferator-activated receptor delta.

Siezen CL, Tijhuis MJ, Kram NR, van Soest EM, de Jong DJ, Fodde R, van Kranen HJ, Kampman E.

Pharmacogenet Genomics. 2006 Jan;16(1):43-50.

PMID:
16344721
28.

Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice.

Rebel H, Kram N, Westerman A, Banus S, van Kranen HJ, de Gruijl FR.

Carcinogenesis. 2005 Dec;26(12):2123-30. Epub 2005 Jul 28.

PMID:
16051635
29.

Transcription-coupled repair: impact on UV-induced mutagenesis in cultured rodent cells and mouse skin tumors.

van Zeeland AA, Vreeswijk MP, de Gruijl FR, van Kranen HJ, Vrieling H, Mullenders LF.

Mutat Res. 2005 Sep 4;577(1-2):170-8. Review.

PMID:
15949822
30.

Dose-dependent effects of UVB-induced skin carcinogenesis in hairless p53 knockout mice.

van Kranen HJ, Westerman A, Berg RJ, Kram N, van Kreijl CF, Wester PW, de Gruijl FR.

Mutat Res. 2005 Apr 1;571(1-2):81-90.

PMID:
15748640
31.

Genetic control of Bordetella pertussis infection: identification of susceptibility loci using recombinant congenic strains of mice.

Banus HA, van Kranen HJ, Mooi FR, Hoebee B, Nagelkerke NJ, Demant P, Kimman TG.

Infect Immun. 2005 Feb;73(2):741-7.

32.

Effects of soy-derived isoflavones and a high-fat diet on spontaneous mammary tumor development in Tg.NK (MMTV/c-neu) mice.

Luijten M, Thomsen AR, van den Berg JA, Wester PW, Verhoef A, Nagelkerke NJ, Adlercreutz H, van Kranen HJ, Piersma AH, Sørensen IK, Rao GN, van Kreijl CF.

Nutr Cancer. 2004;50(1):46-54.

PMID:
15572297
33.

Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption.

Siezen CL, van Leeuwen AI, Kram NR, Luken ME, van Kranen HJ, Kampman E.

Carcinogenesis. 2005 Feb;26(2):449-57. Epub 2004 Nov 18.

PMID:
15550453
34.

UV exposure, genetic targets in melanocytic tumors and transgenic mouse models.

de Gruijl FR, van Kranen HJ, van Schanke A.

Photochem Photobiol. 2005 Jan-Feb;81(1):52-64.

PMID:
15535734
35.

Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes.

van Oosten M, Stout GJ, Backendorf C, Rebel H, de Wind N, Darroudi F, van Kranen HJ, de Gruijl FR, Mullenders LH.

DNA Repair (Amst). 2005 Jan 2;4(1):81-9.

PMID:
15533840
36.

Lignan precursors from flaxseed or rye bran do not protect against the development of intestinal neoplasia in ApcMin mice.

van Kranen HJ, Mortensen A, Sørensen IK, van den Berg-Wijnands J, Beems R, Nurmi T, Adlercreutz H, van Kreijl CF.

Nutr Cancer. 2003;45(2):203-10.

PMID:
12881015
37.

Tissue levels of fish fatty acids and risk of colorectal adenomas: a case-control study (Netherlands).

Busstra MC, Siezen CL, Grubben MJ, van Kranen HJ, Nagengast FM, van't Veer P.

Cancer Causes Control. 2003 Apr;14(3):269-76.

PMID:
12814206
38.

The DNA damage signal for Mdm2 regulation, Trp53 induction, and sunburn cell formation in vivo originates from actively transcribed genes.

Brash DE, Wikonkal NM, Remenyik E, van der Horst GT, Friedberg EC, Cheo DL, van Steeg H, Westerman A, van Kranen HJ.

J Invest Dermatol. 2001 Nov;117(5):1234-40.

39.

UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer.

de Gruijl FR, van Kranen HJ, Mullenders LH.

J Photochem Photobiol B. 2001 Oct;63(1-3):19-27. Review.

PMID:
11684448
40.

Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity.

Rebel H, Mosnier LO, Berg RJ, Westerman-de Vries A, van Steeg H, van Kranen HJ, de Gruijl FR.

Cancer Res. 2001 Feb 1;61(3):977-83.

41.

Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis.

van Oosten M, Rebel H, Friedberg EC, van Steeg H, van der Horst GT, van Kranen HJ, Westerman A, van Zeeland AA, Mullenders LH, de Gruijl FR.

Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11268-73.

42.

Impact of global genome repair versus transcription-coupled repair on ultraviolet carcinogenesis in hairless mice.

Berg RJ, Rebel H, van der Horst GT, van Kranen HJ, Mullenders LH, van Vloten WA, de Gruijl FR.

Cancer Res. 2000 Jun 1;60(11):2858-63.

43.

Balancing the risks and benefits of drinking water disinfection: disability adjusted life-years on the scale.

Havelaar AH, De Hollander AE, Teunis PF, Evers EG, Van Kranen HJ, Versteegh JF, Van Koten JE, Slob W.

Environ Health Perspect. 2000 Apr;108(4):315-21.

44.

Mutations in cancer genes of UV-induced skin tumors of hairless mice.

van Kranen HJ, de Gruijl FR.

J Epidemiol. 1999 Dec;9(6 Suppl):S58-65. Review.

PMID:
10709351
45.

Effects of dietary fat and a vegetable-fruit mixture on the development of intestinal neoplasia in the ApcMin mouse.

van Kranen HJ, van Iersel PW, Rijnkels JM, Beems DB, Alink GM, van Kreijl CF.

Carcinogenesis. 1998 Sep;19(9):1597-601.

PMID:
9771930
46.

The effect of soy isoflavones on the development of intestinal neoplasia in ApcMin mouse.

Sørensen IK, Kristiansen E, Mortensen A, Nicolaisen GM, Wijnands JA, van Kranen HJ, van Kreijl CF.

Cancer Lett. 1998 Aug 14;130(1-2):217-25.

PMID:
9751277
47.

XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B.

de Vries A, Berg RJ, Wijnhoven S, Westerman A, Wester PW, van Kreijl CF, Capel PJ, de Gruijl FR, van Kranen HJ, van Steeg H.

Oncogene. 1998 Apr 30;16(17):2205-12.

48.

Use of E mu-PIM-1 transgenic mice short-term in vivo carcinogenicity testing: lymphoma induction by benzo[a]pyrene, but not by TPA.

Kroese ED, Dortant PM, van Steeg H, van Oostrom CT, van der Houven van Oordt CW, van Kranen HJ, de Vries A, Wester PW, van Kreijl CF.

Carcinogenesis. 1997 May;18(5):975-80.

PMID:
9163683
49.

The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice.

Dumaz N, van Kranen HJ, de Vries A, Berg RJ, Wester PW, van Kreijl CF, Sarasin A, Daya-Grosjean L, de Gruijl FR.

Carcinogenesis. 1997 May;18(5):897-904.

PMID:
9163673
50.

Low incidence of p53 mutations in UVA (365-nm)-induced skin tumors in hairless mice.

van Kranen HJ, de Laat A, van de Ven J, Wester PW, de Vries A, Berg RJ, van Kreijl CF, de Gruijl FR.

Cancer Res. 1997 Apr 1;57(7):1238-40.

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