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Items: 1 to 50 of 279

1.

Brain Death Enhances Activation of the Innate Immune System and Leads to Reduced Renal Metabolic Gene Expression.

Zitur LJ, Chlebeck PJ, Odorico SK, Danobeitia JS, Zens TJ, Van Kooten C, Eerhart M, Reyes JA, Springer ML, Coonen JM, Brunner KG, Capuano SV, D'Alessandro AM, Fernandez LA.

Transplantation. 2019 Apr 4. doi: 10.1097/TP.0000000000002744. [Epub ahead of print]

PMID:
30964836
2.

Clinical Implications of Excessive Neutrophil Extracellular Trap Formation in Renal Autoimmune Diseases.

van Dam LS, Rabelink TJ, van Kooten C, Teng YKO.

Kidney Int Rep. 2018 Nov 19;4(2):196-211. doi: 10.1016/j.ekir.2018.11.005. eCollection 2019 Feb. Review.

3.

A High-throughput Assay to Assess and Quantify Neutrophil Extracellular Trap Formation.

Arends EJ, van Dam LS, Kraaij T, Kamerling SWA, Rabelink TJ, van Kooten C, Teng YKO.

J Vis Exp. 2019 Jan 29;(143). doi: 10.3791/59150.

PMID:
30774133
4.

Diagnosis and treatment of C3 glomerulopathy in a center of expertise.

Koopman JJE, Teng YKO, Boon CJF, van den Heuvel LP, Rabelink TJ, van Kooten C, de Vries APJ.

Neth J Med. 2019 Jan;77(1):10-18.

5.

Vascular bioengineering of scaffolds derived from human discarded transplant kidneys using human pluripotent stem cell-derived endothelium.

Leuning DG, Witjas FMR, Maanaoui M, de Graaf AMA, Lievers E, Geuens T, Avramut CM, Wiersma LE, van den Berg CW, Sol WMPJ, de Boer H, Wang G, LaPointe VLS, van der Vlag J, van Kooten C, van den Berg BM, Little MH, Engelse MA, Rabelink TJ.

Am J Transplant. 2019 May;19(5):1328-1343. doi: 10.1111/ajt.15200. Epub 2019 Jan 10.

PMID:
30506641
6.

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.

Gaya da Costa M, Poppelaars F, van Kooten C, Mollnes TE, Tedesco F, Würzner R, Trouw LA, Truedsson L, Daha MR, Roos A, Seelen MA.

Front Immunol. 2018 Nov 20;9:2664. doi: 10.3389/fimmu.2018.02664. eCollection 2018.

7.

An Easy and Sensitive Method to Profile the Antibody Specificities of HLA-specific Memory B Cells.

Karahan GE, Krop J, Wehmeier C, de Vaal YJH, Langerak-Langerak J, Roelen DL, Lardy NM, Bemelman FJ, Ten Berge IJM, Reinders MEJ, van Kooten C, Claas FHJ, Heidt S.

Transplantation. 2019 Apr;103(4):716-723. doi: 10.1097/TP.0000000000002516.

8.

Properdin binds independent of complement activation in an in vivo model of anti-glomerular basement membrane disease.

O'Flynn J, Kotimaa J, Faber-Krol R, Koekkoek K, Klar-Mohamad N, Koudijs A, Schwaeble WJ, Stover C, Daha MR, van Kooten C.

Kidney Int. 2018 Dec;94(6):1141-1150. doi: 10.1016/j.kint.2018.06.030. Epub 2018 Oct 12.

PMID:
30322716
9.

Urinary TIMP-2 Predicts the Presence and Duration of Delayed Graft Function in Donation After Circulatory Death Kidney Transplant Recipients.

Bank JR, Ruhaak R, Soonawala D, Mayboroda O, Romijn FP, van Kooten C, Cobbaert CM, de Fijter JW.

Transplantation. 2019 May;103(5):1014-1023. doi: 10.1097/TP.0000000000002472.

PMID:
30300282
10.

Role of properdin in complement-mediated kidney diseases.

van Essen MF, Ruben JM, de Vries APJ, van Kooten C; COMBAT consortium .

Nephrol Dial Transplant. 2019 May 1;34(5):742-750. doi: 10.1093/ndt/gfy233.

PMID:
30053164
11.

Enhanced activation of interleukin-10, heme oxygenase-1, and AKT in C5aR2-deficient mice is associated with protection from ischemia reperfusion injury-induced inflammation and fibrosis.

Thorenz A, Derlin K, Schröder C, Dressler L, Vijayan V, Pradhan P, Immenschuh S, Jörns A, Echtermeyer F, Herzog C, Chen R, Rong S, Bräsen JH, van Kooten C, Kirsch T, Klemann C, Meier M, Klos A, Haller H, Hensen B, Gueler F.

Kidney Int. 2018 Oct;94(4):741-755. doi: 10.1016/j.kint.2018.04.005. Epub 2018 Jun 21.

PMID:
29935951
12.

Urinary metabolites predict prolonged duration of delayed graft function in DCD kidney transplant recipients.

Kostidis S, Bank JR, Soonawala D, Nevedomskaya E, van Kooten C, Mayboroda OA, de Fijter JW.

Am J Transplant. 2019 Jan;19(1):110-122. doi: 10.1111/ajt.14941. Epub 2018 Jun 15.

PMID:
29786954
13.

The cytokine secretion profile of mesenchymal stromal cells is determined by surface structure of the microenvironment.

Leuning DG, Beijer NRM, du Fossé NA, Vermeulen S, Lievers E, van Kooten C, Rabelink TJ, Boer J.

Sci Rep. 2018 May 16;8(1):7716. doi: 10.1038/s41598-018-25700-5.

14.

Complement Activation in Patients With Diabetic Nephropathy.

Bus P, Chua JS, Klessens CQF, Zandbergen M, Wolterbeek R, van Kooten C, Trouw LA, Bruijn JA, Baelde HJ.

Kidney Int Rep. 2017 Oct 16;3(2):302-313. doi: 10.1016/j.ekir.2017.10.005. eCollection 2018 Mar.

15.

Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis.

Michailidou I, Jongejan A, Vreijling JP, Georgakopoulou T, de Wissel MB, Wolterman RA, Ruizendaal P, Klar-Mohamad N, Grootemaat AE, Picavet DI, Kumar V, van Kooten C, Woodruff TM, Morgan BP, van der Wel NN, Ramaglia V, Fluiter K, Baas F.

Acta Neuropathol Commun. 2018 May 3;6(1):36. doi: 10.1186/s40478-018-0536-y.

16.

The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus.

Kraaij T, Kamerling SWA, de Rooij ENM, van Daele PLA, Bredewold OW, Bakker JA, Bajema IM, Scherer HU, Toes REM, Huizinga TJW, Rabelink TJ, van Kooten C, Teng YKO.

J Autoimmun. 2018 Jul;91:45-54. doi: 10.1016/j.jaut.2018.03.003. Epub 2018 Apr 7.

PMID:
29636274
17.

Excessive neutrophil extracellular trap formation in ANCA-associated vasculitis is independent of ANCA.

Kraaij T, Kamerling SWA, van Dam LS, Bakker JA, Bajema IM, Page T, Brunini F, Pusey CD, Toes REM, Scherer HU, Rabelink TJ, van Kooten C, Teng YKO.

Kidney Int. 2018 Jul;94(1):139-149. doi: 10.1016/j.kint.2018.01.013. Epub 2018 Mar 30.

18.

A Restricted Role for FcγR in the Regulation of Adaptive Immunity.

Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS.

J Immunol. 2018 Apr 15;200(8):2615-2626. doi: 10.4049/jimmunol.1700429. Epub 2018 Mar 9.

19.

Elevated intragraft expression of innate immunity and cell death-related markers is a risk factor for adverse graft outcome.

Yang J, Snijders MLH, Haasnoot GW, van Kooten C, Mallat M, de Fijter JW, Clahsen-van Groningen MC, Claas FHJ, Eikmans M.

Transpl Immunol. 2018 Jun;48:39-46. doi: 10.1016/j.trim.2018.02.009. Epub 2018 Feb 20.

PMID:
29475090
20.

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, Cuturi MC, Geissler E, Giannoukakis N, Gołab K, Hafler DA, van Ham SM, Hester J, Hippen K, Di Ianni M, Ilic N, Isaacs J, Issa F, Iwaszkiewicz-Grześ D, Jaeckel E, Joosten I, Klatzmann D, Koenen H, van Kooten C, Korsgren O, Kretschmer K, Levings M, Marek-Trzonkowska NM, Martinez-Llordella M, Miljkovic D, Mills KHG, Miranda JP, Piccirillo CA, Putnam AL, Ritter T, Roncarolo MG, Sakaguchi S, Sánchez-Ramón S, Sawitzki B, Sofronic-Milosavljevic L, Sykes M, Tang Q, Vives-Pi M, Waldmann H, Witkowski P, Wood KJ, Gregori S, Hilkens CMU, Lombardi G, Lord P, Martinez-Caceres EM, Trzonkowski P.

Front Immunol. 2018 Jan 15;8:1844. doi: 10.3389/fimmu.2017.01844. eCollection 2017.

21.

The human kidney capsule contains a functionally distinct mesenchymal stromal cell population.

Leuning DG, Engelse MA, Lievers E, Bijkerk R, Reinders MEJ, de Boer HC, van Kooten C, Rabelink TJ.

PLoS One. 2017 Dec 5;12(12):e0187118. doi: 10.1371/journal.pone.0187118. eCollection 2017.

22.

Human plasmacytoid dendritic cells acquire phagocytic capacity by TLR9 ligation in the presence of soluble factors produced by renal epithelial cells.

Ruben JM, García-Romo GS, Breman E, van der Kooij S, Redeker A, Arens R, van Kooten C.

Kidney Int. 2018 Feb;93(2):355-364. doi: 10.1016/j.kint.2017.08.006. Epub 2017 Oct 20.

PMID:
29061332
23.

Kidney injury molecule-1 staining in renal allograft biopsies 10 days after transplantation is inversely correlated with functioning proximal tubular epithelial cells.

Bank JR, van der Pol P, Vreeken D, Monge-Chaubo C, Bajema IM, Schlagwein N, van Gijlswijk DJ, van der Kooij SW, Reinders MEJ, de Fijter JW, van Kooten C.

Nephrol Dial Transplant. 2017 Dec 1;32(12):2132-2141. doi: 10.1093/ndt/gfx286.

PMID:
29045706
24.

Local delivery of liposomal prednisolone leads to an anti-inflammatory profile in renal ischaemia-reperfusion injury in the rat.

van Alem CMA, Boonstra M, Prins J, Bezhaeva T, van Essen MF, Ruben JM, Vahrmeijer AL, van der Veer EP, de Fijter JW, Reinders ME, Meijer O, Metselaar JM, van Kooten C, Rotmans JI.

Nephrol Dial Transplant. 2018 Jan 1;33(1):44-53. doi: 10.1093/ndt/gfx204.

PMID:
28992069
25.

IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement.

van Dam AD, van Beek L, Pronk ACM, van den Berg SM, Van den Bossche J, de Winther MPJ, Koning F, van Kooten C, Rensen PCN, Boon MR, Verbeek JS, van Dijk KW, van Harmelen V.

Int J Obes (Lond). 2018 Feb;42(2):260-269. doi: 10.1038/ijo.2017.209. Epub 2017 Aug 30.

PMID:
28852207
26.

Systemic Monocyte Chemotactic Protein-1 Inhibition Modifies Renal Macrophages and Restores Glomerular Endothelial Glycocalyx and Barrier Function in Diabetic Nephropathy.

Boels MGS, Koudijs A, Avramut MC, Sol WMPJ, Wang G, van Oeveren-Rietdijk AM, van Zonneveld AJ, de Boer HC, van der Vlag J, van Kooten C, Eulberg D, van den Berg BM, IJpelaar DHT, Rabelink TJ.

Am J Pathol. 2017 Nov;187(11):2430-2440. doi: 10.1016/j.ajpath.2017.07.020. Epub 2017 Aug 22.

27.

A Novel Clinical Grade Isolation Method for Human Kidney Perivascular Stromal Cells.

Leuning DG, Lievers E, Reinders MEJ, van Kooten C, Engelse MA, Rabelink TJ.

J Vis Exp. 2017 Aug 7;(126). doi: 10.3791/55841.

28.

C1-Inhibitor Treatment Decreases Renal Injury in an Established Brain-Dead Rat Model.

Poppelaars F, Jager NM, Kotimaa J, Leuvenink HGD, Daha MR, van Kooten C, Seelen MA, Damman J.

Transplantation. 2018 Jan;102(1):79-87. doi: 10.1097/TP.0000000000001895.

PMID:
28731906
29.

Infectious pathogens may trigger specific allo-HLA reactivity via multiple mechanisms.

D'Orsogna L, van den Heuvel H, van Kooten C, Heidt S, Claas FHJ.

Immunogenetics. 2017 Aug;69(8-9):631-641. doi: 10.1007/s00251-017-0989-3. Epub 2017 Jul 17. Review.

30.

Mesenchymal Stromal Cell Therapy for Solid Organ Transplantation.

Reinders MEJ, van Kooten C, Rabelink TJ, de Fijter JW.

Transplantation. 2018 Jan;102(1):35-43. doi: 10.1097/TP.0000000000001879. Review.

PMID:
28704335
31.

Systemic complement activation in central serous chorioretinopathy.

van Dijk EHC, Tsonaka R, Klar-Mohamad N, Wouters D, de Vries APJ, de Jong EK, van Kooten C, Boon CJF.

PLoS One. 2017 Jul 3;12(7):e0180312. doi: 10.1371/journal.pone.0180312. eCollection 2017.

32.

Counteracting dysfunction of regulatory T cells in organ transplantation.

van Kooten C.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):6883-6884. doi: 10.1073/pnas.1708493114. Epub 2017 Jun 22. No abstract available.

33.

Critical role for complement receptor C5aR2 in the pathogenesis of renal ischemia-reperfusion injury.

Poppelaars F, van Werkhoven MB, Kotimaa J, Veldhuis ZJ, Ausema A, Broeren SGM, Damman J, Hempel JC, Leuvenink HGD, Daha MR, van Son WJ, van Kooten C, van Os RP, Hillebrands JL, Seelen MA.

FASEB J. 2017 Jul;31(7):3193-3204. doi: 10.1096/fj.201601218R. Epub 2017 Apr 10.

PMID:
28396344
34.

Production of complement components by cells of the immune system.

Lubbers R, van Essen MF, van Kooten C, Trouw LA.

Clin Exp Immunol. 2017 May;188(2):183-194. doi: 10.1111/cei.12952. Epub 2017 Mar 24. Review.

35.

Clinical-Grade Isolated Human Kidney Perivascular Stromal Cells as an Organotypic Cell Source for Kidney Regenerative Medicine.

Leuning DG, Reinders ME, Li J, Peired AJ, Lievers E, de Boer HC, Fibbe WE, Romagnani P, van Kooten C, Little MH, Engelse MA, Rabelink TJ.

Stem Cells Transl Med. 2017 Feb;6(2):405-418. doi: 10.5966/sctm.2016-0053. Epub 2016 Sep 20.

36.

Neutrophil Protease Cleavage of Von Willebrand Factor in Glomeruli - An Anti-thrombotic Mechanism in the Kidney.

Tati R, Kristoffersson AC, Manea Hedström M, Mörgelin M, Wieslander J, van Kooten C, Karpman D.

EBioMedicine. 2017 Feb;16:302-311. doi: 10.1016/j.ebiom.2017.01.032. Epub 2017 Jan 24.

37.

Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-γ.

Dixon KO, O'Flynn J, Klar-Mohamad N, Daha MR, van Kooten C.

Eur J Immunol. 2017 Mar;47(3):470-480. doi: 10.1002/eji.201646703.

38.

Mesenchymal stromal cells in clinical kidney transplantation: how tolerant can it be?

van Kooten C, Rabelink TJ, de Fijter JW, Reinders ME.

Curr Opin Organ Transplant. 2016 Dec;21(6):550-558. Review.

PMID:
27755168
39.

Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies.

Lord P, Spiering R, Aguillon JC, Anderson AE, Appel S, Benitez-Ribas D, Ten Brinke A, Broere F, Cools N, Cuturi MC, Diboll J, Geissler EK, Giannoukakis N, Gregori S, van Ham SM, Lattimer S, Marshall L, Harry RA, Hutchinson JA, Isaacs JD, Joosten I, van Kooten C, Lopez Diaz de Cerio A, Nikolic T, Oral HB, Sofronic-Milosavljevic L, Ritter T, Riquelme P, Thomson AW, Trucco M, Vives-Pi M, Martinez-Caceres EM, Hilkens CMU.

PeerJ. 2016 Aug 30;4:e2300. doi: 10.7717/peerj.2300. eCollection 2016.

40.

Uptake of HLA Alloantigens via CD89 and CD206 Does Not Enhance Antigen Presentation by Indirect Allorecognition.

Breman E, Ruben JM, Franken KL, Heemskerk MH, Roelen DL, Claas FH, van Kooten C.

J Immunol Res. 2016;2016:4215684. doi: 10.1155/2016/4215684. Epub 2016 Jun 20.

41.

Sex matters: Systemic complement activity of female C57BL/6J and BALB/cJ mice is limited by serum terminal pathway components.

Kotimaa J, Klar-Mohammad N, Gueler F, Schilders G, Jansen A, Rutjes H, Daha MR, van Kooten C.

Mol Immunol. 2016 Aug;76:13-21. doi: 10.1016/j.molimm.2016.06.004. Epub 2016 Jun 20.

42.

Microarray Gene Expression Analysis to Evaluate Cell Type Specific Expression of Targets Relevant for Immunotherapy of Hematological Malignancies.

Pont MJ, Honders MW, Kremer AN, van Kooten C, Out C, Hiemstra PS, de Boer HC, Jager MJ, Schmelzer E, Vries RG, Al Hinai AS, Kroes WG, Monajemi R, Goeman JJ, Böhringer S, Marijt WA, Falkenburg JH, Griffioen M.

PLoS One. 2016 May 12;11(5):e0155165. doi: 10.1371/journal.pone.0155165. eCollection 2016.

43.

Anti-carbamylated protein antibodies: a specific hallmark for rheumatoid arthritis. Comparison to conditions known for enhanced carbamylation; renal failure, smoking and chronic inflammation.

Verheul MK, van Erp SJ, van der Woude D, Levarht EW, Mallat MJ, Verspaget HW, Stolk J, Toes RE, van der Meulen-de Jong AE, Hiemstra PS, van Kooten C, Trouw LA.

Ann Rheum Dis. 2016 Aug;75(8):1575-6. doi: 10.1136/annrheumdis-2016-209248. Epub 2016 Apr 29. No abstract available.

PMID:
27130909
44.

Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression.

de Bruin RG, Shiue L, Prins J, de Boer HC, Singh A, Fagg WS, van Gils JM, Duijs JM, Katzman S, Kraaijeveld AO, Böhringer S, Leung WY, Kielbasa SM, Donahue JP, van der Zande PH, Sijbom R, van Alem CM, Bot I, van Kooten C, Jukema JW, Van Esch H, Rabelink TJ, Kazan H, Biessen EA, Ares M Jr, van Zonneveld AJ, van der Veer EP.

Nat Commun. 2016 Mar 31;7:10846. doi: 10.1038/ncomms10846.

45.

Monomeric C-reactive protein inhibits renal cell-directed complement activation mediated by properdin.

O'Flynn J, van der Pol P, Dixon KO, Prohászka Z, Daha MR, van Kooten C.

Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1308-16. doi: 10.1152/ajprenal.00645.2014. Epub 2016 Mar 16.

46.

Proteomics of Urinary Vesicles Links Plakins and Complement to Polycystic Kidney Disease.

Salih M, Demmers JA, Bezstarosti K, Leonhard WN, Losekoot M, van Kooten C, Gansevoort RT, Peters DJ, Zietse R, Hoorn EJ; DIPAK Consortium.

J Am Soc Nephrol. 2016 Oct;27(10):3079-3092. Epub 2016 Mar 3.

47.

A novel method for high-throughput detection and quantification of neutrophil extracellular traps reveals ROS-independent NET release with immune complexes.

Kraaij T, Tengström FC, Kamerling SW, Pusey CD, Scherer HU, Toes RE, Rabelink TJ, van Kooten C, Teng YK.

Autoimmun Rev. 2016 Jun;15(6):577-84. doi: 10.1016/j.autrev.2016.02.018. Epub 2016 Feb 27. Review.

48.

Simultaneous pancreas-kidney transplantation in patients with type 1 diabetes reverses elevated MBL levels in association with MBL2 genotype and VEGF expression.

Bijkerk R, van der Pol P, Khairoun M, van Gijlswijk-Jansen DJ, Lievers E, de Vries AP, de Koning EJ, de Fijter HW, Roelen DL, Vossen RH, van Zonneveld AJ, van Kooten C, Reinders ME.

Diabetologia. 2016 Apr;59(4):853-8. doi: 10.1007/s00125-015-3858-3. Epub 2016 Jan 15.

49.

Beneficial Immune Effects of Myeloid-Related Proteins in Kidney Transplant Rejection.

Rekers NV, Bajema IM, Mallat MJ, Petersen B, Anholts JD, Swings GM, van Miert PP, Kerkhoff C, Roth J, Popp D, van Groningen MC, Baeten D, Goemaere N, Kraaij MD, Zandbergen M, Heidt S, van Kooten C, de Fijter JW, Claas FH, Eikmans M.

Am J Transplant. 2016 May;16(5):1441-55. doi: 10.1111/ajt.13634. Epub 2016 Feb 1.

50.

Introducing this special issue.

van Kooten C, Villadangos JA.

Mol Immunol. 2015 Nov;68(1):1. doi: 10.1016/j.molimm.2015.09.009. No abstract available.

PMID:
26597197

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