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Items: 1 to 50 of 290

1.

JNK2 in myeloid cells impairs insulin's vasodilator effects in muscle during early obesity development through perivascular adipose tissue dysfunction.

Meijer RI, Hoevenaars FPM, Serné EH, Yudkin JS, Kokhuis TJA, Weijers EM, van Hinsbergh VWM, Smulders YM, Eringa EC.

Am J Physiol Heart Circ Physiol. 2019 Aug 1;317(2):H364-H374. doi: 10.1152/ajpheart.00663.2018. Epub 2019 May 31.

PMID:
31149833
2.

Hypoxia Impairs Initial Outgrowth of Endothelial Colony Forming Cells and Reduces Their Proliferative and Sprouting Potential.

Tasev D, Dekker-Vroling L, van Wijhe M, Broxterman HJ, Koolwijk P, van Hinsbergh VWM.

Front Med (Lausanne). 2018 Dec 20;5:356. doi: 10.3389/fmed.2018.00356. eCollection 2018.

3.

A functional siRNA screen identifies RhoGTPase-associated genes involved in thrombin-induced endothelial permeability.

Amado-Azevedo J, de Menezes RX, van Nieuw Amerongen GP, van Hinsbergh VWM, Hordijk PL.

PLoS One. 2018 Jul 26;13(7):e0201231. doi: 10.1371/journal.pone.0201231. eCollection 2018.

4.

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 Aug;21(3):425-532. doi: 10.1007/s10456-018-9613-x. Review.

5.

Insulin Receptor Substrate 2 Controls Insulin-Mediated Vasoreactivity and Perivascular Adipose Tissue Function in Muscle.

Turaihi AH, Bakker W, van Hinsbergh VWM, Serné EH, Smulders YM, Niessen HWM, Eringa EC.

Front Physiol. 2018 Mar 23;9:245. doi: 10.3389/fphys.2018.00245. eCollection 2018.

6.

Endothelial permeability, LDL deposition, and cardiovascular risk factors-a review.

Mundi S, Massaro M, Scoditti E, Carluccio MA, van Hinsbergh VWM, Iruela-Arispe ML, De Caterina R.

Cardiovasc Res. 2018 Jan 1;114(1):35-52. doi: 10.1093/cvr/cvx226. Review.

PMID:
29228169
7.

The minor histocompatibility antigen 1 (HMHA1)/ArhGAP45 is a RacGAP and a novel regulator of endothelial integrity.

Amado-Azevedo J, Reinhard NR, van Bezu J, van Nieuw Amerongen GP, van Hinsbergh VWM, Hordijk PL.

Vascul Pharmacol. 2018 Feb;101:38-47. doi: 10.1016/j.vph.2017.11.007. Epub 2017 Nov 21.

PMID:
29174013
8.

RhoA, RhoB and RhoC differentially regulate endothelial barrier function.

Pronk MCA, van Bezu JSM, van Nieuw Amerongen GP, van Hinsbergh VWM, Hordijk PL.

Small GTPases. 2019 Nov;10(6):466-484. doi: 10.1080/21541248.2017.1339767. Epub 2017 Sep 26.

9.

A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity.

Amado-Azevedo J, Reinhard NR, van Bezu J, de Menezes RX, van Beusechem VW, van Nieuw Amerongen GP, van Hinsbergh VWM, Hordijk PL.

Sci Rep. 2017 Aug 31;7(1):10132. doi: 10.1038/s41598-017-10392-0.

10.

Combined Intravital Microscopy and Contrast-enhanced Ultrasonography of the Mouse Hindlimb to Study Insulin-induced Vasodilation and Muscle Perfusion.

Turaihi AH, van Poelgeest EM, van Hinsbergh VW, Serné EH, Smulders YM, Eringa EC.

J Vis Exp. 2017 Mar 20;(121). doi: 10.3791/54912.

11.

PX-18 Protects Human Saphenous Vein Endothelial Cells under Arterial Blood Pressure.

Kupreishvili K, Stooker W, Emmens RW, Vonk ABA, Sipkens JA, van Dijk A, Eijsman L, Quax PH, van Hinsbergh VWM, Krijnen PAJ, Niessen HWM.

Ann Vasc Surg. 2017 Jul;42:293-298. doi: 10.1016/j.avsg.2016.10.063. Epub 2017 Mar 11.

PMID:
28300679
12.

Endothelial Progenitors: A Consensus Statement on Nomenclature.

Medina RJ, Barber CL, Sabatier F, Dignat-George F, Melero-Martin JM, Khosrotehrani K, Ohneda O, Randi AM, Chan JKY, Yamaguchi T, Van Hinsbergh VWM, Yoder MC, Stitt AW.

Stem Cells Transl Med. 2017 May;6(5):1316-1320. doi: 10.1002/sctm.16-0360. Epub 2017 Mar 10. Review.

13.

Arterial Blood Pressure Induces Transient C4b-Binding Protein in Human Saphenous Vein Grafts.

Kupreishvili K, Meischl C, Vonk ABA, Stooker W, Eijsman L, Blom AM, Quax PHA, van Hinsbergh VWM, Niessen HWM, Krijnen PAJ.

Ann Vasc Surg. 2017 May;41:259-264. doi: 10.1016/j.avsg.2016.10.033. Epub 2017 Feb 3.

PMID:
28163174
14.

Exercise effects on perivascular adipose tissue: endocrine and paracrine determinants of vascular function.

Boa BCS, Yudkin JS, van Hinsbergh VWM, Bouskela E, Eringa EC.

Br J Pharmacol. 2017 Oct;174(20):3466-3481. doi: 10.1111/bph.13732. Epub 2017 Mar 16. Review.

15.

Transdifferentiation of Human Dermal Fibroblasts to Smooth Muscle-Like Cells to Study the Effect of MYH11 and ACTA2 Mutations in Aortic Aneurysms.

Yeung KK, Bogunovic N, Keekstra N, Beunders AA, Pals J, van der Kuij K, Overwater E, Wisselink W, Blankensteijn JD, van Hinsbergh VW, Musters RJ, Pals G, Micha D, Zandieh-Doulabi B.

Hum Mutat. 2017 Apr;38(4):439-450. doi: 10.1002/humu.23174. Epub 2017 Jan 27.

PMID:
28074631
16.

Osteoglycin's embracement of VEGF receptor-2 limits angiogenesis and collateralization.

van Hinsbergh VW.

Cardiovasc Res. 2017 Jan;113(1):10-12. doi: 10.1093/cvr/cvw243. No abstract available.

PMID:
28069698
17.

Perivascular fat in human muscle.

Meijer RI, Serne EH, Yudkin JS, van Hinsbergh VW, Smulders YM, Eringa EC.

Lancet Diabetes Endocrinol. 2016 Nov;4(11):958. doi: 10.1016/S2213-8587(15)00520-3. Epub 2016 Feb 24. No abstract available.

PMID:
26928650
18.

Identification of HIF-2α-regulated genes that play a role in human microvascular endothelial sprouting during prolonged hypoxia in vitro.

Nauta TD, van den Broek M, Gibbs S, van der Pouw-Kraan TC, Oudejans CB, van Hinsbergh VW, Koolwijk P.

Angiogenesis. 2017 Feb;20(1):39-54. doi: 10.1007/s10456-016-9527-4. Epub 2016 Oct 3.

19.

Correction: HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells.

Nauta TD, Duyndam MC, Weijers EM, van Hinsbergh VW, Koolwijk P.

PLoS One. 2016 Sep 22;11(9):e0163840. doi: 10.1371/journal.pone.0163840. eCollection 2016.

20.

Traction force dynamics predict gap formation in activated endothelium.

Valent ET, van Nieuw Amerongen GP, van Hinsbergh VW, Hordijk PL.

Exp Cell Res. 2016 Sep 10;347(1):161-70. doi: 10.1016/j.yexcr.2016.07.029. Epub 2016 Aug 3.

PMID:
27498166
21.

Using cultured endothelial cells to study endothelial barrier dysfunction: Challenges and opportunities.

Aman J, Weijers EM, van Nieuw Amerongen GP, Malik AB, van Hinsbergh VW.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L453-66. doi: 10.1152/ajplung.00393.2015. Epub 2016 Jun 24. Review.

22.

Mast cells are increased in the media of coronary lesions in patients with myocardial infarction and may favor atherosclerotic plaque instability.

Kupreishvili K, Fuijkschot WW, Vonk AB, Smulders YM, Stooker W, Van Hinsbergh VW, Niessen HW, Krijnen PA.

J Cardiol. 2017 Mar;69(3):548-554. doi: 10.1016/j.jjcc.2016.04.018. Epub 2016 Jun 7.

23.

Development of a new therapeutic technique to direct stem cells to the infarcted heart using targeted microbubbles: StemBells.

Woudstra L, Krijnen PA, Bogaards SJ, Meinster E, Emmens RW, Kokhuis TJ, Bollen IA, Baltzer H, Baart SM, Parbhudayal R, Helder MN, van Hinsbergh VW, Musters RJ, de Jong N, Kamp O, Niessen HW, van Dijk A, Juffermans LJ.

Stem Cell Res. 2016 Jul;17(1):6-15. doi: 10.1016/j.scr.2016.04.018. Epub 2016 Apr 30.

24.

CD34 expression modulates tube-forming capacity and barrier properties of peripheral blood-derived endothelial colony-forming cells (ECFCs).

Tasev D, Konijnenberg LS, Amado-Azevedo J, van Wijhe MH, Koolwijk P, van Hinsbergh VW.

Angiogenesis. 2016 Jul;19(3):325-38. doi: 10.1007/s10456-016-9506-9. Epub 2016 Apr 4.

25.

Therapeutic Potential of Human-Derived Endothelial Colony-Forming Cells in Animal Models.

Tasev D, Koolwijk P, van Hinsbergh VW.

Tissue Eng Part B Rev. 2016 Oct;22(5):371-382. Epub 2016 May 10. Review.

PMID:
27032435
26.

C1q/TNF-related protein 1: a novel link between visceral fat and athero-inflammation.

van Hinsbergh VW, Eringa EC.

Eur Heart J. 2016 Jun 7;37(22):1772-4. doi: 10.1093/eurheartj/ehv754. Epub 2016 Feb 2. No abstract available.

PMID:
26843273
27.

Globular adiponectin controls insulin-mediated vasoreactivity in muscle through AMPKα2.

de Boer MP, Meijer RI, Richter EA, van Nieuw Amerongen GP, Sipkema P, van Poelgeest EM, Aman J, Kokhuis TJ, Koolwijk P, van Hinsbergh VW, Smulders YM, Serné EH, Eringa EC.

Vascul Pharmacol. 2016 Mar;78:24-35. doi: 10.1016/j.vph.2015.09.002. Epub 2015 Sep 10.

PMID:
26363472
28.

Neovascularization of the atherosclerotic plaque: interplay between atherosclerotic lesion, adventitia-derived microvessels and perivascular fat.

van Hinsbergh VW, Eringa EC, Daemen MJ.

Curr Opin Lipidol. 2015 Oct;26(5):405-11. doi: 10.1097/MOL.0000000000000210. Review.

PMID:
26241102
29.

Platelets and thromboxane receptors: pivotal players in arteriogenesis.

Van Hinsbergh VW, Tasev D.

Cardiovasc Res. 2015 Sep 1;107(4):400-2. doi: 10.1093/cvr/cvv194. Epub 2015 Jul 9. No abstract available.

PMID:
26160325
30.

Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting Capacity.

Tasev D, van Wijhe MH, Weijers EM, van Hinsbergh VW, Koolwijk P.

PLoS One. 2015 Jun 15;10(6):e0129935. doi: 10.1371/journal.pone.0129935. eCollection 2015.

31.

Insulin-induced changes in skeletal muscle microvascular perfusion are dependent upon perivascular adipose tissue in women.

Meijer RI, Serné EH, Korkmaz HI, van der Peet DL, de Boer MP, Niessen HW, van Hinsbergh VW, Yudkin JS, Smulders YM, Eringa EC.

Diabetologia. 2015 Aug;58(8):1907-15. doi: 10.1007/s00125-015-3606-8. Epub 2015 May 24.

32.

ROCK2 primes the endothelium for vascular hyperpermeability responses by raising baseline junctional tension.

Beckers CM, Knezevic N, Valent ET, Tauseef M, Krishnan R, Rajendran K, Hardin CC, Aman J, van Bezu J, Sweetnam P, van Hinsbergh VW, Mehta D, van Nieuw Amerongen GP.

Vascul Pharmacol. 2015 Jul;70:45-54. doi: 10.1016/j.vph.2015.03.017. Epub 2015 Apr 11.

33.

Hypoxic signaling during tissue repair and regenerative medicine.

Nauta TD, van Hinsbergh VW, Koolwijk P.

Int J Mol Sci. 2014 Oct 31;15(11):19791-815. doi: 10.3390/ijms151119791. Review.

34.

C57BL/6 NK cell gene complex is crucially involved in vascular remodeling.

de Vries MR, Seghers L, van Bergen J, Peters HA, de Jong RC, Hamming JF, Toes RE, van Hinsbergh VW, Quax PH.

J Mol Cell Cardiol. 2013 Nov;64:51-8. doi: 10.1016/j.yjmcc.2013.08.009. Epub 2013 Sep 5.

PMID:
24013026
35.

Localized RhoA GTPase activity regulates dynamics of endothelial monolayer integrity.

Szulcek R, Beckers CM, Hodzic J, de Wit J, Chen Z, Grob T, Musters RJ, Minshall RD, van Hinsbergh VW, van Nieuw Amerongen GP.

Cardiovasc Res. 2013 Aug 1;99(3):471-82. doi: 10.1093/cvr/cvt075. Epub 2013 Mar 27.

36.

Endothelial dysfunction in (pre)diabetes: characteristics, causative mechanisms and pathogenic role in type 2 diabetes.

Eringa EC, Serne EH, Meijer RI, Schalkwijk CG, Houben AJ, Stehouwer CD, Smulders YM, van Hinsbergh VW.

Rev Endocr Metab Disord. 2013 Mar;14(1):39-48. doi: 10.1007/s11154-013-9239-7. Review.

PMID:
23417760
37.

Effective treatment of edema and endothelial barrier dysfunction with imatinib.

Aman J, van Bezu J, Damanafshan A, Huveneers S, Eringa EC, Vogel SM, Groeneveld AB, Vonk Noordegraaf A, van Hinsbergh VW, van Nieuw Amerongen GP.

Circulation. 2012 Dec 4;126(23):2728-38. doi: 10.1161/CIRCULATIONAHA.112.134304. Epub 2012 Oct 25.

PMID:
23099479
38.

Perivascular adipose tissue control of insulin-induced vasoreactivity in muscle is impaired in db/db mice.

Meijer RI, Bakker W, Alta CL, Sipkema P, Yudkin JS, Viollet B, Richter EA, Smulders YM, van Hinsbergh VW, Serné EH, Eringa EC.

Diabetes. 2013 Feb;62(2):590-8. doi: 10.2337/db11-1603. Epub 2012 Oct 9.

39.

Tie2 lineage deletion of α6 integrin: endothelial and haematopoietic cells in neovascularization.

van Hinsbergh VW.

Cardiovasc Res. 2012 Jul 1;95(1):5-6. doi: 10.1093/cvr/cvs171. No abstract available.

PMID:
22717730
40.

Human platelet lysate as a fetal bovine serum substitute improves human adipose-derived stromal cell culture for future cardiac repair applications.

Naaijkens BA, Niessen HW, Prins HJ, Krijnen PA, Kokhuis TJ, de Jong N, van Hinsbergh VW, Kamp O, Helder MN, Musters RJ, van Dijk A, Juffermans LJ.

Cell Tissue Res. 2012 Apr;348(1):119-30. doi: 10.1007/s00441-012-1360-5. Epub 2012 Mar 7.

41.

Paracrine regulation of vascular tone, inflammation and insulin sensitivity by perivascular adipose tissue.

Eringa EC, Bakker W, van Hinsbergh VW.

Vascul Pharmacol. 2012 May-Jun;56(5-6):204-9. doi: 10.1016/j.vph.2012.02.003. Epub 2012 Feb 15. Review.

PMID:
22366250
42.

Proximal fluid proteome profiling of mouse colon tumors reveals biomarkers for early diagnosis of human colorectal cancer.

Fijneman RJ, de Wit M, Pourghiasian M, Piersma SR, Pham TV, Warmoes MO, Lavaei M, Piso C, Smit F, Delis-van Diemen PM, van Turenhout ST, Terhaar sive Droste JS, Mulder CJ, Blankenstein MA, Robanus-Maandag EC, Smits R, Fodde R, van Hinsbergh VW, Meijer GA, Jimenez CR.

Clin Cancer Res. 2012 May 1;18(9):2613-24. doi: 10.1158/1078-0432.CCR-11-1937. Epub 2012 Feb 20.

43.

Endothelial insulin receptor expression in human atherosclerotic plaques: linking micro- and macrovascular disease in diabetes?

Rensing KL, von der Thüsen JH, Weijers EM, Houttuijn Bloemendaal FM, van Lammeren GW, Vink A, van der Wal AC, van Hinsbergh VW, van der Loos CM, Stroes ES, Koolwijk P, Twickler TB.

Atherosclerosis. 2012 May;222(1):208-15. doi: 10.1016/j.atherosclerosis.2012.01.035. Epub 2012 Jan 28.

44.

S-Adenosylhomocysteine induces apoptosis and phosphatidylserine exposure in endothelial cells independent of homocysteine.

Sipkens JA, Hahn NE, Blom HJ, Lougheed SM, Stehouwer CD, Rauwerda JA, Krijnen PA, van Hinsbergh VW, Niessen HW.

Atherosclerosis. 2012 Mar;221(1):48-54. doi: 10.1016/j.atherosclerosis.2011.11.032. Epub 2011 Nov 28.

PMID:
22204864
45.

Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients.

Krijnen PA, Hahn NE, Kholová I, Baylan U, Sipkens JA, van Alphen FP, Vonk AB, Simsek S, Meischl C, Schalkwijk CG, van Buul JD, van Hinsbergh VW, Niessen HW.

Basic Res Cardiol. 2012 Jan;107(1):233. doi: 10.1007/s00395-011-0233-5. Epub 2011 Dec 14.

46.

C1-esterase inhibitor protects against early vein graft remodeling under arterial blood pressure.

Krijnen PA, Kupreishvili K, de Vries MR, Schepers A, Stooker W, Vonk AB, Eijsman L, Van Hinsbergh VW, Zeerleder S, Wouters D, van Ham M, Quax PH, Niessen HW.

Atherosclerosis. 2012 Jan;220(1):86-92. doi: 10.1016/j.atherosclerosis.2011.10.021. Epub 2011 Oct 25.

47.

Homocysteine-induced apoptosis in endothelial cells coincides with nuclear NOX2 and peri-nuclear NOX4 activity.

Sipkens JA, Hahn N, van den Brand CS, Meischl C, Cillessen SA, Smith DE, Juffermans LJ, Musters RJ, Roos D, Jakobs C, Blom HJ, Smulders YM, Krijnen PA, Stehouwer CD, Rauwerda JA, van Hinsbergh VW, Niessen HW.

Cell Biochem Biophys. 2013 Nov;67(2):341-52. doi: 10.1007/s12013-011-9297-y.

48.

Sunitinib-induced changes in circulating endothelial cell-related proteins in patients with metastatic renal cell cancer.

van der Veldt AA, Vroling L, de Haas RR, Koolwijk P, van den Eertwegh AJ, Haanen JB, van Hinsbergh VW, Broxterman HJ, Boven E.

Int J Cancer. 2012 Aug 15;131(4):E484-93. doi: 10.1002/ijc.26456. Epub 2011 Nov 8.

49.

Homocysteine induces phosphatidylserine exposure in cardiomyocytes through inhibition of Rho kinase and flippase activity.

Sipkens JA, Hahn NE, van Nieuw-Amerongen GP, Stehouwer CD, Rauwerda JA, van Hinsbergh VW, Niessen HW, Krijnen PA.

Cell Physiol Biochem. 2011;28(1):53-62. doi: 10.1159/000331713. Epub 2011 Aug 16.

50.

Opposing effects of the angiopoietins on the thrombin-induced permeability of human pulmonary microvascular endothelial cells.

van der Heijden M, van Nieuw Amerongen GP, van Bezu J, Paul MA, Groeneveld AB, van Hinsbergh VW.

PLoS One. 2011;6(8):e23448. doi: 10.1371/journal.pone.0023448. Epub 2011 Aug 15.

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