Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 60


Robust protocol for feeder-free adaptation of cryopreserved human pluripotent stem cells.

Aalders J, Van den Vreken N, Popovic M, Mishra S, Heindryckx B, van Hengel J.

In Vitro Cell Dev Biol Anim. 2019 Oct 29. doi: 10.1007/s11626-019-00413-9. [Epub ahead of print]


Deletion of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 in Mouse T Cells Protects Against Development of Autoimmune Arthritis but Leads to Spontaneous Osteoporosis.

Gilis E, Gaublomme D, Staal J, Venken K, Dhaenens M, Lambrecht S, Coudenys J, Decruy T, Schryvers N, Driege Y, Dumas E, Demeyer A, De Muynck A, van Hengel J, Van Hoorebeke L, Deforce D, Beyaert R, Elewaut D.

Arthritis Rheumatol. 2019 Jul 1. doi: 10.1002/art.41029. [Epub ahead of print]


Armc8 is an evolutionarily conserved armadillo protein involved in cell-cell adhesion complexes through multiple molecular interactions.

Gul IS, Hulpiau P, Sanders E, van Roy F, van Hengel J.

Biosci Rep. 2019 Aug 2;39(8). pii: BSR20180604. doi: 10.1042/BSR20180604. Print 2019 Aug 30.


A heart for fibrillin: spatial arrangement in adult wild-type murine myocardial tissue.

Steijns F, van Hengel J, Sips P, De Backer J, Renard M.

Histochem Cell Biol. 2018 Sep;150(3):271-280. doi: 10.1007/s00418-018-1686-5. Epub 2018 Jun 20.


Three-dimensional reconstruction of the intercalated disc including the intercellular junctions by applying volume scanning electron microscopy.

Vanslembrouck B, Kremer A, Pavie B, van Roy F, Lippens S, van Hengel J.

Histochem Cell Biol. 2018 May;149(5):479-490. doi: 10.1007/s00418-018-1657-x. Epub 2018 Mar 5.


Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange.

Pieters T, Haenebalcke L, Bruneel K, Vandamme N, Hochepied T, van Hengel J, Wirth D, Berx G, Haigh JJ, van Roy F, Goossens S.

J Vis Exp. 2017 Apr 27;(122). doi: 10.3791/55575.


Inactivation of p120 catenin in mice disturbs intrahepatic bile duct development and aggravates liver carcinogenesis.

van Hengel J, Van den Broeke C, Pieters T, Libbrecht L, Hofmann I, van Roy F.

Eur J Cell Biol. 2016 Dec;95(12):574-584. doi: 10.1016/j.ejcb.2016.10.003. Epub 2016 Oct 15.


RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism.

García-Mariscal A, Peyrollier K, Basse A, Pedersen E, Rühl R, van Hengel J, Brakebusch C.

Small GTPases. 2018 Sep 3;9(5):433-444. doi: 10.1080/21541248.2016.1248272. Epub 2016 Nov 16.


p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification.

Pieters T, Goossens S, Haenebalcke L, Andries V, Stryjewska A, De Rycke R, Lemeire K, Hochepied T, Huylebroeck D, Berx G, Stemmler MP, Wirth D, Haigh JJ, van Hengel J, van Roy F.

PLoS Genet. 2016 Aug 24;12(8):e1006243. doi: 10.1371/journal.pgen.1006243. eCollection 2016 Aug.


αT-catenin in restricted brain cell types and its potential connection to autism.

Folmsbee SS, Wilcox DR, Tyberghein K, De Bleser P, Tourtellotte WG, van Hengel J, van Roy F, Gottardi CJ.

J Mol Psychiatry. 2016 Jun 21;4:2. doi: 10.1186/s40303-016-0017-9. eCollection 2016.


Beta-Catenin and Plakoglobin Expression during Zebrafish Tooth Development and Replacement.

Verstraeten B, van Hengel J, Huysseune A.

PLoS One. 2016 Mar 3;11(3):e0148114. doi: 10.1371/journal.pone.0148114. eCollection 2016.


Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice.

Sklyarova T, van Hengel J, Van Wonterghem E, Libert C, van Roy F, Vandenbroucke RE.

Eur J Immunol. 2015 Oct;45(10):2898-910. doi: 10.1002/eji.201445440. Epub 2015 Aug 6.


Intercalated discs and arrhythmogenic cardiomyopathy.

Rampazzo A, Calore M, van Hengel J, van Roy F.

Circ Cardiovasc Genet. 2014 Dec;7(6):930-40. doi: 10.1161/CIRCGENETICS.114.000645. No abstract available.


The cardiac protein αT-catenin contributes to chemical-induced asthma.

Folmsbee SS, Morales-Nebreda L, Van Hengel J, Tyberghein K, Van Roy F, Budinger GR, Bryce PJ, Gottardi CJ.

Am J Physiol Lung Cell Mol Physiol. 2015 Feb 1;308(3):L253-8. doi: 10.1152/ajplung.00331.2014. Epub 2014 Dec 5.


N-cadherin is required for cytodifferentiation during zebrafish odontogenesis.

Verstraeten B, van Hengel J, Sanders E, Van Roy F, Huysseune A.

J Dent Res. 2013 Apr;92(4):365-70. doi: 10.1177/0022034513477424. Epub 2013 Feb 8.


Mutations in the area composita protein αT-catenin are associated with arrhythmogenic right ventricular cardiomyopathy.

van Hengel J, Calore M, Bauce B, Dazzo E, Mazzotti E, De Bortoli M, Lorenzon A, Li Mura IE, Beffagna G, Rigato I, Vleeschouwers M, Tyberghein K, Hulpiau P, van Hamme E, Zaglia T, Corrado D, Basso C, Thiene G, Daliento L, Nava A, van Roy F, Rampazzo A.

Eur Heart J. 2013 Jan;34(3):201-10. doi: 10.1093/eurheartj/ehs373. Epub 2012 Nov 7.


Ocular anterior segment dysgenesis upon ablation of p120 catenin in neural crest cells.

Tian H, Sanders E, Reynolds A, van Roy F, van Hengel J.

Invest Ophthalmol Vis Sci. 2012 Aug 7;53(9):5139-53. doi: 10.1167/iovs.12-9472.


Interaction of α-catulin with dystrobrevin contributes to integrity of dystrophin complex in muscle.

Oh HJ, Abraham LS, van Hengel J, Stove C, Proszynski TJ, Gevaert K, DiMario JX, Sanes JR, van Roy F, Kim H.

J Biol Chem. 2012 Jun 22;287(26):21717-28. doi: 10.1074/jbc.M112.369496. Epub 2012 May 10.


Tissue-wide overexpression of alpha-T-catenin results in aberrant trophoblast invasion but does not cause embryonic mortality in mice.

Tyberghein K, Goossens S, Haigh JJ, van Roy F, van Hengel J.

Placenta. 2012 Jul;33(7):554-60. doi: 10.1016/j.placenta.2012.04.002. Epub 2012 Apr 23.


Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia.

Li J, Goossens S, van Hengel J, Gao E, Cheng L, Tyberghein K, Shang X, De Rycke R, van Roy F, Radice GL.

J Cell Sci. 2012 Feb 15;125(Pt 4):1058-67. doi: 10.1242/jcs.098640. Epub 2012 Mar 15.


A radial glia-specific role of RhoA in double cortex formation.

Cappello S, Böhringer CR, Bergami M, Conzelmann KK, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Götz M.

Neuron. 2012 Mar 8;73(5):911-24. doi: 10.1016/j.neuron.2011.12.030.


Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling.

Pieters T, van Roy F, van Hengel J.

Front Biosci (Landmark Ed). 2012 Jan 1;17:1669-94. Review.


Functions of p120ctn in development and disease.

Pieters T, van Hengel J, van Roy F.

Front Biosci (Landmark Ed). 2012 Jan 1;17:760-83. Review.


Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis.

Pleines I, Hagedorn I, Gupta S, May F, Chakarova L, van Hengel J, Offermanns S, Krohne G, Kleinschnitz C, Brakebusch C, Nieswandt B.

Blood. 2012 Jan 26;119(4):1054-63. doi: 10.1182/blood-2011-08-372193. Epub 2011 Nov 1.


Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells.

Pieters T, Haenebalcke L, Hochepied T, D'Hont J, Haigh JJ, van Roy F, van Hengel J.

Stem Cell Rev Rep. 2012 Sep;8(3):768-78. doi: 10.1007/s12015-011-9323-x.


The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool.

Herzog D, Loetscher P, van Hengel J, Knüsel S, Brakebusch C, Taylor V, Suter U, Relvas JB.

J Neurosci. 2011 Mar 30;31(13):5120-30. doi: 10.1523/JNEUROSCI.4807-10.2011.


RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes.

Jackson B, Peyrollier K, Pedersen E, Basse A, Karlsson R, Wang Z, Lefever T, Ochsenbein AM, Schmidt G, Aktories K, Stanley A, Quondamatteo F, Ladwein M, Rottner K, van Hengel J, Brakebusch C.

Mol Biol Cell. 2011 Mar 1;22(5):593-605. doi: 10.1091/mbc.E09-10-0859. Epub 2011 Jan 5.


Zebrafish teeth as a model for repetitive epithelial morphogenesis: dynamics of E-cadherin expression.

Verstraeten B, Sanders E, van Hengel J, Huysseune A.

BMC Dev Biol. 2010 Jun 1;10:58. doi: 10.1186/1471-213X-10-58.


The transcriptional repressor Kaiso localizes at the mitotic spindle and is a constituent of the pericentriolar material.

Soubry A, Staes K, Parthoens E, Noppen S, Stove C, Bogaert P, van Hengel J, van Roy F.

PLoS One. 2010 Feb 15;5(2):e9203. doi: 10.1371/journal.pone.0009203.


Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes.

Van den Bossche J, Bogaert P, van Hengel J, Guérin CJ, Berx G, Movahedi K, Van den Bergh R, Pereira-Fernandes A, Geuns JM, Pircher H, Dorny P, Grooten J, De Baetselier P, Van Ginderachter JA.

Blood. 2009 Nov 19;114(21):4664-74. doi: 10.1182/blood-2009-05-221598. Epub 2009 Sep 2.


Endoplasmic reticulum quality control: a new mechanism of E-cadherin regulation and its implication in cancer.

Simões-Correia J, Figueiredo J, Oliveira C, van Hengel J, Seruca R, van Roy F, Suriano G.

Hum Mol Genet. 2008 Nov 15;17(22):3566-76. doi: 10.1093/hmg/ddn249. Epub 2008 Sep 4.


Continuous cell injury promotes hepatic tumorigenesis in cdc42-deficient mouse liver.

van Hengel J, D'Hooge P, Hooghe B, Wu X, Libbrecht L, De Vos R, Quondamatteo F, Klempt M, Brakebusch C, van Roy F.

Gastroenterology. 2008 Mar;134(3):781-92. doi: 10.1053/j.gastro.2008.01.002. Epub 2008 Jan 9.


Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation.

Sklyarova T, Bonné S, D'Hooge P, Denecker G, Goossens S, De Rycke R, Borgonie G, Bösl M, van Roy F, van Hengel J.

J Invest Dermatol. 2008 Jun;128(6):1375-85. Epub 2007 Dec 13.


Alpha-catulin, a Rho signalling component, can regulate NF-kappaB through binding to IKK-beta, and confers resistance to apoptosis.

Wiesner C, Winsauer G, Resch U, Hoeth M, Schmid JA, van Hengel J, van Roy F, Binder BR, de Martin R.

Oncogene. 2008 Apr 3;27(15):2159-69. Epub 2007 Oct 22.


A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs.

Goossens S, Janssens B, Bonné S, De Rycke R, Braet F, van Hengel J, van Roy F.

J Cell Sci. 2007 Jun 15;120(Pt 12):2126-36. Epub 2007 May 29.


Truncated isoform of mouse alphaT-catenin is testis-restricted in expression and function.

Goossens S, Janssens B, Vanpoucke G, De Rycke R, van Hengel J, van Roy F.

FASEB J. 2007 Mar;21(3):647-55. Epub 2006 Dec 21.


Diverse functions of p120ctn in tumors.

van Hengel J, van Roy F.

Biochim Biophys Acta. 2007 Jan;1773(1):78-88. Epub 2006 Aug 30. Review.


[Covered shortage: Can there be a lack of veterinarians at the human health services?].

van Hengel JF, van Knapen F.

Tijdschr Diergeneeskd. 2006 Jul 1;131(13):492-3. Dutch. No abstract available.


Nuclear translocation of alphaN-catenin by the novel zinc finger transcriptional repressor ZASC1.

Bogaerts S, Vanlandschoot A, van Hengel J, van Roy F.

Exp Cell Res. 2005 Nov 15;311(1):1-13. Epub 2005 Sep 22.


Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells.

Czuchra A, Wu X, Meyer H, van Hengel J, Schroeder T, Geffers R, Rottner K, Brakebusch C.

Mol Biol Cell. 2005 Oct;16(10):4473-84. Epub 2005 Jul 12. Erratum in: Mol Biol Cell. 2005 Dec;16(12):5901.


Expression and nuclear location of the transcriptional repressor Kaiso is regulated by the tumor microenvironment.

Soubry A, van Hengel J, Parthoens E, Colpaert C, Van Marck E, Waltregny D, Reynolds AB, van Roy F.

Cancer Res. 2005 Mar 15;65(6):2224-33.


Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness.

Kotelevets L, van Hengel J, Bruyneel E, Mareel M, van Roy F, Chastre E.

FASEB J. 2005 Jan;19(1):115-7. Epub 2004 Nov 1.


Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.

Busby V, Goossens S, Nowotny P, Hamilton G, Smemo S, Harold D, Turic D, Jehu L, Myers A, Womick M, Woo D, Compton D, Doil LM, Tacey KM, Lau KF, Al-Saraj S, Killick R, Pickering-Brown S, Moore P, Hollingworth P, Archer N, Foy C, Walter S, Lendon C, Iwatsubo T, Morris JC, Norton J, Mann D, Janssens B, Hardy J, O'Donovan M, Jones L, Williams J, Holmans P, Owen MJ, Grupe A, Powell J, van Hengel J, Goate A, Van Roy F, Lovestone S.

Neuromolecular Med. 2004;5(2):133-46.


Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy.

Janssens B, Mohapatra B, Vatta M, Goossens S, Vanpoucke G, Kools P, Montoye T, van Hengel J, Bowles NE, van Roy F, Towbin JA.

Hum Genet. 2003 Mar;112(3):227-36. Epub 2002 Dec 5.


A novel role for p120 catenin in E-cadherin function.

Ireton RC, Davis MA, van Hengel J, Mariner DJ, Barnes K, Thoreson MA, Anastasiadis PZ, Matrisian L, Bundy LM, Sealy L, Gilbert B, van Roy F, Reynolds AB.

J Cell Biol. 2002 Nov 11;159(3):465-76. Epub 2002 Nov 11.


Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells.

Müller N, Reinacher-Schick A, Baldus S, van Hengel J, Berx G, Baar A, van Roy F, Schmiegel W, Schwarte-Waldhoff I.

Oncogene. 2002 Sep 5;21(39):6049-58.


The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness.

Kotelevets L, van Hengel J, Bruyneel E, Mareel M, van Roy F, Chastre E.

J Cell Biol. 2001 Dec 24;155(7):1129-35. Epub 2001 Dec 24.


alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.

Janssens B, Goossens S, Staes K, Gilbert B, van Hengel J, Colpaert C, Bruyneel E, Mareel M, van Roy F.

J Cell Sci. 2001 Sep;114(Pt 17):3177-88.


The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 catenin.

Keilhack H, Hellman U, van Hengel J, van Roy F, Godovac-Zimmermann J, Böhmer FD.

J Biol Chem. 2000 Aug 25;275(34):26376-84.


Supplemental Content

Loading ...
Support Center