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Items: 1 to 50 of 79

1.

Venous Vasomotion.

van Helden DF, Imtiaz MS.

Adv Exp Med Biol. 2019;1124:313-328. doi: 10.1007/978-981-13-5895-1_13. Review.

PMID:
31183833
2.

Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814.

Walweel K, Gomez-Hurtado N, Rebbeck RT, Oo YW, Beard NA, Molenaar P, Dos Remedios C, van Helden DF, Cornea RL, Knollmann BC, Laver DR.

J Mol Cell Cardiol. 2019 May;130:96-106. doi: 10.1016/j.yjmcc.2019.03.018. Epub 2019 Mar 27.

3.

Crosstalk between mitochondria, calcium channels and actin cytoskeleton modulates noradrenergic activity of locus coeruleus neurons.

de Oliveira RB, Petiz LL, Lim R, Lipski J, Gravina FS, Brichta AM, Callister RJ, Leão RN, van Helden DF.

J Neurochem. 2019 May;149(4):471-487. doi: 10.1111/jnc.14692. Epub 2019 Apr 2.

PMID:
30828804
4.

Endothelial tubes: another window into lymphatic function.

Dora KA, van Helden DF.

J Physiol. 2017 Dec 15;595(24):7267-7268. doi: 10.1113/JP275323. Epub 2017 Nov 21. No abstract available.

5.

Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels.

Walweel K, Gomez-Hurtado N, Oo YW, Beard NA, Dos Remedios C, Johnson CN, Chazin WJ, van Helden DF, Knollmann BC, Laver DR.

J Am Coll Cardiol. 2017 Jul 4;70(1):115-117. doi: 10.1016/j.jacc.2017.04.055. No abstract available.

6.

Nerve-induced responses of mouse vaginal smooth muscle.

van Helden DF, Kamiya A, Kelsey S, Laver DR, Jobling P, Mitsui R, Hashitani H.

Pflugers Arch. 2017 Oct;469(10):1373-1385. doi: 10.1007/s00424-017-1995-x. Epub 2017 May 27.

PMID:
28551705
7.

Ryanodine receptor modification and regulation by intracellular Ca2+ and Mg2+ in healthy and failing human hearts.

Walweel K, Molenaar P, Imtiaz MS, Denniss A, Dos Remedios C, van Helden DF, Dulhunty AF, Laver DR, Beard NA.

J Mol Cell Cardiol. 2017 Mar;104:53-62. doi: 10.1016/j.yjmcc.2017.01.016. Epub 2017 Jan 26.

PMID:
28131631
8.

Pacemaker role of pericytes in generating synchronized spontaneous Ca2+ transients in the myenteric microvasculature of the guinea-pig gastric antrum.

Hashitani H, Mitsui R, Masaki S, Van Helden DF.

Cell Calcium. 2015 Nov;58(5):442-56. doi: 10.1016/j.ceca.2015.06.012. Epub 2015 Jun 30.

PMID:
26153078
9.

Plasma Membrane Ca2+-Permeable Channels are Differentially Regulated by Ethylene and Hydrogen Peroxide to Generate Persistent Plumes of Elevated Cytosolic Ca2+ During Transfer Cell Trans-Differentiation.

Zhang HM, van Helden DF, McCurdy DW, Offler CE, Patrick JW.

Plant Cell Physiol. 2015 Sep;56(9):1711-20. doi: 10.1093/pcp/pcv100. Epub 2015 Jul 1.

PMID:
26139237
10.

Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

Oo YW, Gomez-Hurtado N, Walweel K, van Helden DF, Imtiaz MS, Knollmann BC, Laver DR.

Mol Pharmacol. 2015 Jul;88(1):57-63. doi: 10.1124/mol.115.097691. Epub 2015 Apr 28.

11.

Single mechanically-gated cation channel currents can trigger action potentials in neocortical and hippocampal pyramidal neurons.

Nikolaev YA, Dosen PJ, Laver DR, van Helden DF, Hamill OP.

Brain Res. 2015 May 22;1608:1-13. doi: 10.1016/j.brainres.2015.02.051. Epub 2015 Mar 9.

PMID:
25765154
12.

Intracranial pressure elevation reduces flow through collateral vessels and the penetrating arterioles they supply. A possible explanation for 'collateral failure' and infarct expansion after ischemic stroke.

Beard DJ, McLeod DD, Logan CL, Murtha LA, Imtiaz MS, van Helden DF, Spratt NJ.

J Cereb Blood Flow Metab. 2015 May;35(5):861-72. doi: 10.1038/jcbfm.2015.2. Epub 2015 Feb 11.

13.

The lymphangion: a not so 'primitive' heart.

van Helden DF.

J Physiol. 2014 Dec 15;592(24):5353-4. doi: 10.1113/jphysiol.2014.286039. No abstract available.

14.

Polarized and persistent Ca²⁺ plumes define loci for formation of wall ingrowth papillae in transfer cells.

Zhang HM, Imtiaz MS, Laver DR, McCurdy DW, Offler CE, van Helden DF, Patrick JW.

J Exp Bot. 2015 Mar;66(5):1179-90. doi: 10.1093/jxb/eru460. Epub 2014 Dec 10.

15.

Phasic contractions of the mouse vagina and cervix at different phases of the estrus cycle and during late pregnancy.

Gravina FS, van Helden DF, Kerr KP, de Oliveira RB, Jobling P.

PLoS One. 2014 Oct 22;9(10):e111307. doi: 10.1371/journal.pone.0111307. eCollection 2014.

16.

Multiple modes of ryanodine receptor 2 inhibition by flecainide.

Mehra D, Imtiaz MS, van Helden DF, Knollmann BC, Laver DR.

Mol Pharmacol. 2014 Dec;86(6):696-706. doi: 10.1124/mol.114.094623. Epub 2014 Oct 1.

17.

Differences in the regulation of RyR2 from human, sheep, and rat by Ca²⁺ and Mg²⁺ in the cytoplasm and in the lumen of the sarcoplasmic reticulum.

Walweel K, Li J, Molenaar P, Imtiaz MS, Quail A, dos Remedios CG, Beard NA, Dulhunty AF, van Helden DF, Laver DR.

J Gen Physiol. 2014 Sep;144(3):263-71. doi: 10.1085/jgp.201311157.

18.

Pharmacological approaches that slow lymphatic flow as a snakebite first aid.

van Helden DF, Thomas PA, Dosen PJ, Imtiaz MS, Laver DR, Isbister GK.

PLoS Negl Trop Dis. 2014 Feb 27;8(2):e2722. doi: 10.1371/journal.pntd.0002722. eCollection 2014 Feb.

19.

Heterogeneous responses to antioxidants in noradrenergic neurons of the Locus coeruleus indicate differing susceptibility to free radical content.

de Oliveira RB, Gravina FS, Lim R, Brichta AM, Callister RJ, van Helden DF.

Oxid Med Cell Longev. 2012;2012:820285. doi: 10.1155/2012/820285. Epub 2012 Apr 12.

20.

Developmental changes in pacemaker currents in mouse locus coeruleus neurons.

de Oliveira RB, Gravina FS, Lim R, Brichta AM, Callister RJ, van Helden DF.

Brain Res. 2011 Nov 24;1425:27-36. doi: 10.1016/j.brainres.2011.09.053. Epub 2011 Oct 1.

PMID:
22018689
21.

A pharmacological approach to first aid treatment for snakebite.

Saul ME, Thomas PA, Dosen PJ, Isbister GK, O'Leary MA, Whyte IM, McFadden SA, van Helden DF.

Nat Med. 2011 Jun 26;17(7):809-11. doi: 10.1038/nm.2382.

PMID:
21706027
22.

Oxytocin depolarizes mitochondria in isolated myometrial cells.

Gravina FS, Jobling P, Kerr KP, de Oliveira RB, Parkington HC, van Helden DF.

Exp Physiol. 2011 Sep;96(9):949-56. doi: 10.1113/expphysiol.2011.058388. Epub 2011 Jun 10.

23.

Three independent mechanisms contribute to tetracaine inhibition of cardiac calcium release channels.

Laver DR, van Helden DF.

J Mol Cell Cardiol. 2011 Sep;51(3):357-69. doi: 10.1016/j.yjmcc.2011.05.009. Epub 2011 May 19.

PMID:
21624373
24.

Role of mitochondria in contraction and pacemaking in the mouse uterus.

Gravina FS, Parkington HC, Kerr KP, de Oliveira RB, Jobling P, Coleman HA, Sandow SL, Davies MM, Imtiaz MS, van Helden DF.

Br J Pharmacol. 2010 Nov;161(6):1375-90. doi: 10.1111/j.1476-5381.2010.00949.x.

25.

Pacemaker currents in mouse locus coeruleus neurons.

de Oliveira RB, Howlett MC, Gravina FS, Imtiaz MS, Callister RJ, Brichta AM, van Helden DF.

Neuroscience. 2010 Sep 29;170(1):166-77. doi: 10.1016/j.neuroscience.2010.06.028. Epub 2010 Jul 8.

PMID:
20620193
26.

Ketamine anesthesia helps preserve neuronal viability.

de Oliveira RB, Graham B, Howlett MC, Gravina FS, Oliveira MW, Imtiaz MS, Callister RJ, Lim R, Brichta AM, van Helden DF.

J Neurosci Methods. 2010 Jun 15;189(2):230-2. doi: 10.1016/j.jneumeth.2010.03.029. Epub 2010 Apr 7.

PMID:
20380852
27.

SR Ca2+ store refill--a key factor in cardiac pacemaking.

Imtiaz MS, von der Weid PY, Laver DR, van Helden DF.

J Mol Cell Cardiol. 2010 Sep;49(3):412-26. doi: 10.1016/j.yjmcc.2010.03.015. Epub 2010 Mar 29.

PMID:
20353793
28.

Generation and propagation of gastric slow waves.

van Helden DF, Laver DR, Holdsworth J, Imtiaz MS.

Clin Exp Pharmacol Physiol. 2010 Apr;37(4):516-24. doi: 10.1111/j.1440-1681.2009.05331.x. Epub 2009 Nov 23. Review.

PMID:
19930430
29.

Synchronization of Ca2+ oscillations: a coupled oscillator-based mechanism in smooth muscle.

Imtiaz MS, von der Weid PY, van Helden DF.

FEBS J. 2010 Jan;277(2):278-85. doi: 10.1111/j.1742-4658.2009.07437.x. Epub 2009 Nov 6. Review.

30.

Spontaneous transient depolarizations in lymphatic vessels of the guinea pig mesentery: pharmacology and implication for spontaneous contractility.

von der Weid PY, Rahman M, Imtiaz MS, van Helden DF.

Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H1989-2000. doi: 10.1152/ajpheart.00007.2008. Epub 2008 Sep 12.

31.

The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels.

Odell AF, Van Helden DF, Scott JL.

J Biol Chem. 2008 Feb 15;283(7):4395-407. Epub 2007 Nov 29.

32.

Pacemaking through Ca2+ stores interacting as coupled oscillators via membrane depolarization.

Imtiaz MS, Zhao J, Hosaka K, von der Weid PY, Crowe M, van Helden DF.

Biophys J. 2007 Jun 1;92(11):3843-61. Epub 2007 Mar 9.

33.

Rhythmicity in the microcirculation.

van Helden DF, Hosaka K, Imtiaz MS.

Clin Hemorheol Microcirc. 2006;34(1-2):59-66. Review.

PMID:
16543618
34.

Calcitonin gene-related peptide activates different signaling pathways in mesenteric lymphatics of guinea pigs.

Hosaka K, Rayner SE, von der Weid PY, Zhao J, Imtiaz MS, van Helden DF.

Am J Physiol Heart Circ Physiol. 2006 Feb;290(2):H813-22. Epub 2005 Sep 19.

35.

Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4.

Odell AF, Scott JL, Van Helden DF.

J Biol Chem. 2005 Nov 11;280(45):37974-87. Epub 2005 Sep 6.

36.

Role of voltage-dependent modulation of store Ca2+ release in synchronization of Ca2+ oscillations.

Imtiaz MS, Katnik CP, Smith DW, van Helden DF.

Biophys J. 2006 Jan 1;90(1):1-23. Epub 2005 Jul 22.

37.

ET-1-associated vasomotion and vasospasm in lymphatic vessels of the guinea-pig mesentery.

Zhao J, van Helden DF.

Br J Pharmacol. 2003 Dec;140(8):1399-413. Epub 2003 Nov 17.

38.

Ca2+ phase waves: a basis for cellular pacemaking and long-range synchronicity in the guinea-pig gastric pylorus.

van Helden DF, Imtiaz MS.

J Physiol. 2003 Apr 1;548(Pt 1):271-96. Epub 2003 Feb 7.

40.
41.

Nitric oxide decreases pacemaker activity in lymphatic vessels of guinea pig mesentery.

von der Weid PY, Zhao J, Van Helden DF.

Am J Physiol Heart Circ Physiol. 2001 Jun;280(6):H2707-16.

42.

Lymphatic vasomotion.

Van Helden DF, Zhao J.

Clin Exp Pharmacol Physiol. 2000 Dec;27(12):1014-8. Review.

PMID:
11117222
43.

Role of calcium stores and membrane voltage in the generation of slow wave action potentials in guinea-pig gastric pylorus.

van Helden DF, Imtiaz MS, Nurgaliyeva K, von der Weid P, Dosen PJ.

J Physiol. 2000 Apr 1;524 Pt 1:245-65.

45.
47.

Co-ordination of contractile activity in guinea-pig mesenteric lymphatics.

Crowe MJ, von der Weid PY, Brock JA, Van Helden DF.

J Physiol. 1997 Apr 1;500 ( Pt 1):235-44.

48.

Prevention of high blood pressure by reducing sympathetic innervation in the spontaneously hypertensive rat.

Brock JA, Van Helden DF, Dosen P, Rush RA.

J Auton Nerv Syst. 1996 Nov 6;61(2):97-102.

PMID:
8946326
49.

Modulation of frog skeletal muscle Ca2+ release channel gating by anion channel blockers.

Oba T, Koshita M, Van Helden DF.

Am J Physiol. 1996 Sep;271(3 Pt 1):C819-24.

PMID:
8843711
50.

Properties of spontaneous depolarizations in circular smooth muscle cells of rabbit urethra.

Hashitani H, Van Helden DF, Suzuki H.

Br J Pharmacol. 1996 Aug;118(7):1627-32.

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