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Items: 44


Differential Elimination of Anti-Thymocyte Globulin of Fresenius and Genzyme Impacts T-Cell Reconstitution After Hematopoietic Stem Cell Transplantation.

Oostenbrink LVE, Jol-van der Zijde CM, Kielsen K, Jansen-Hoogendijk AM, Ifversen M, Müller KG, Lankester AC, van Halteren AGS, Bredius RGM, Schilham MW, van Tol MJD.

Front Immunol. 2019 Mar 6;10:315. doi: 10.3389/fimmu.2019.00315. eCollection 2019.


Lymphoproliferative Disease in the Rectum 4 Years After Local Mesenchymal Stromal Cell Therapy for Refractory Perianal Crohn's Fistulas: A Case Report.

Barnhoorn MC, Van Halteren AGS, Van Pel M, Molendijk I, Struijk AC, Jansen PM, Verspaget HW, Dijkstra G, Oosten LEM, Van der Meulen-de Jong AE.

J Crohns Colitis. 2019 May 27;13(6):807-811. doi: 10.1093/ecco-jcc/jjy220.


A multicenter study of patients with multisystem Langerhans cell histiocytosis who develop secondary hemophagocytic lymphohistiocytosis.

Chellapandian D, Hines MR, Zhang R, Jeng M, van den Bos C, Santa-María López V, Lehmberg K, Sieni E, Wang Y, Nakano T, Williams JA, Fustino NJ, Astigarraga I, Dunkel IJ, Abla O, van Halteren AGS, Pei D, Cheng C, Weitzman S, Sung L, Nichols KE.

Cancer. 2019 Mar 15;125(6):963-971. doi: 10.1002/cncr.31893. Epub 2018 Dec 6.


Tertiary lymphoid structures are confined to patients presenting with unifocal Langerhans Cell Histiocytosis.

Quispel WT, Steenwijk EC, van Unen V, Santos SJ, Koens L, Mebius R, Egeler RM, van Halteren AG.

Oncoimmunology. 2016 Mar 28;5(8):e1164364. doi: 10.1080/2162402X.2016.1164364. eCollection 2016 Aug.


Erratum to: Intact IFN-γR1 Expression and Function Distinguishes Langerhans Cell Histiocytosis From Mendelian Susceptibility to Mycobacterial Disease.

Quispel WT, Stegehuis-Kamp JA, Santos SJ, van Wengen A, Dompeling E, Egeler RM, van de Vosse E, van Halteren AG.

J Clin Immunol. 2016 Feb;36(2):171-2. doi: 10.1007/s10875-016-0235-z. No abstract available.


Activated Conventional T-Cells Are Present in Langerhans Cell Histiocytosis Lesions Despite the Presence of Immune Suppressive Cytokines.

Quispel WT, Stegehuis-Kamp JA, Santos SJ, Egeler RM, van Halteren AG.

J Interferon Cytokine Res. 2015 Oct;35(10):831-9. doi: 10.1089/jir.2014.0190. Epub 2015 Sep 18.


The presence of CXCR4+ CD1a+ cells at onset of Langerhans cell histiocytosis is associated with a less favorable outcome.

Quispel WT, Stegehuis-Kamp JA, Blijleven L, Santos SJ, Lourda M, van den Bos C, van Halteren AG, Egeler RM.

Oncoimmunology. 2015 Aug 31;5(3):e1084463. doi: 10.1080/2162402X.2015.1084463. eCollection 2016 Mar.


The number of T cell allo-epitopes associates with CD4+ and CD8+ T-cell infiltration in pediatric cutaneous GVHD.

Thus KA, van Halteren AG, de Hond TA, van Dijk MR, Kloos RQ, Lankester AC, Bierings MB, Spierings E.

Cell Immunol. 2015 Jun;295(2):112-7. doi: 10.1016/j.cellimm.2015.03.001. Epub 2015 Mar 16.


Donor parity no longer a barrier for female-to-male hematopoietic stem cell transplantation.

van Halteren AG, Dierselhuis MP, Netelenbos T, Fechter M.

Chimerism. 2014;5(2):56-8.


Mesenchymal stromal cell therapy is associated with increased adenovirus-associated but not cytomegalovirus-associated mortality in children with severe acute graft-versus-host disease.

Calkoen FG, Vervat C, van Halteren AG, Welters MJ, Veltrop-Duits LA, Lankester AC, Egeler RM, Ball LM, van Tol MJ.

Stem Cells Transl Med. 2014 Aug;3(8):899-910. doi: 10.5966/sctm.2013-0191. Epub 2014 Jun 5.


Naturally acquired microchimerism: implications for transplantation outcome and novel methodologies for detection.

Eikmans M, van Halteren AG, van Besien K, van Rood JJ, Drabbels JJ, Claas FH.

Chimerism. 2014;5(2):24-39. Review.


Somatic activating ARAF mutations in Langerhans cell histiocytosis.

Nelson DS, Quispel W, Badalian-Very G, van Halteren AG, van den Bos C, Bovée JV, Tian SY, Van Hummelen P, Ducar M, MacConaill LE, Egeler RM, Rollins BJ.

Blood. 2014 May 15;123(20):3152-5. doi: 10.1182/blood-2013-06-511139. Epub 2014 Mar 20.


HY immune tolerance is common in women without male offspring.

Dierselhuis MP, Jankowska-Gan E, Blokland E, Pool J, Burlingham WJ, van Halteren AG, Goulmy E.

PLoS One. 2014 Mar 19;9(3):e91274. doi: 10.1371/journal.pone.0091274. eCollection 2014.


Intact IFN-γR1 expression and function distinguishes Langerhans cell histiocytosis from mendelian susceptibility to mycobacterial disease.

Quispel WT, Stegehuis-Kamp JA, Santos SJ, van Wengen A, Dompeling E, Egeler RM, van de Vosse E, van Halteren AG.

J Clin Immunol. 2014 Jan;34(1):84-93. doi: 10.1007/s10875-013-9959-1. Epub 2013 Nov 20. Review. Erratum in: J Clin Immunol. 2014 Jul;34(5):600. J Clin Immunol. 2016 Feb;36(2):171-2.


Meeting report of the First Symposium on Chimerism.

van Halteren AG, Sedlmayr P, Kroneis T, Burlingham WJ, Nelson JL.

Chimerism. 2013 Oct-Dec;4(4):132-5. doi: 10.4161/chim.27168. Epub 2013 Nov 18. No abstract available.


Gastrointestinal acute graft-versus-host disease in children: histology for diagnosis, mesenchymal stromal cells for treatment, and biomarkers for prediction of response.

Calkoen FG, Jol-van der Zijde CM, Mearin ML, Schweizer JJ, Jansen-Hoogendijk AM, Roelofs H, van Halteren AG, Egeler RM, van Tol MJ, Ball LM.

Biol Blood Marrow Transplant. 2013 Nov;19(11):1590-9. doi: 10.1016/j.bbmt.2013.08.006. Epub 2013 Aug 28.


Decreased levels of circulating IL17-producing CD161+CCR6+ T cells are associated with graft-versus-host disease after allogeneic stem cell transplantation.

van der Waart AB, van der Velden WJ, van Halteren AG, Leenders MJ, Feuth T, Blijlevens NM, van der Voort R, Dolstra H.

PLoS One. 2012;7(12):e50896. doi: 10.1371/journal.pone.0050896. Epub 2012 Dec 4.


In situ detection of HY-specific T cells in acute graft-versus-host disease-affected male skin after sex-mismatched stem cell transplantation.

Kim YH, Faaij CM, van Halteren AG, Schrama E, de Jong TA, Schøller J, Egeler RM, Pavel S, Vyth-Dreese FA, van Tol MJ, Goulmy E, Spierings E.

Biol Blood Marrow Transplant. 2012 Mar;18(3):381-7. doi: 10.1016/j.bbmt.2011.10.038. Epub 2011 Nov 4.


H-Y antibody titers are increased in unexplained secondary recurrent miscarriage patients and associated with low male : female ratio in subsequent live births.

Nielsen HS, Wu F, Aghai Z, Steffensen R, van Halteren AG, Spierings E, Christiansen OB, Miklos D, Goulmy E.

Hum Reprod. 2010 Nov;25(11):2745-52. doi: 10.1093/humrep/deq242. Epub 2010 Sep 7.


Chemokine/chemokine receptor interactions in extramedullary leukaemia of the skin in childhood AML: differential roles for CCR2, CCR5, CXCR4 and CXCR7.

Faaij CM, Willemze AJ, Révész T, Balzarolo M, Tensen CP, Hoogeboom M, Vermeer MH, van Wering E, Zwaan CM, Kaspers GJ, Story C, van Halteren AG, Vossen JM, Egeler RM, van Tol MJ, Annels NE.

Pediatr Blood Cancer. 2010 Aug;55(2):344-8. doi: 10.1002/pbc.22500.


Langerhans cell histiocytosis: fascinating dynamics of the dendritic cell-macrophage lineage.

Egeler RM, van Halteren AG, Hogendoorn PC, Laman JD, Leenen PJ.

Immunol Rev. 2010 Mar;234(1):213-32. doi: 10.1111/j.0105-2896.2009.00883.x. Review.


Islet inflammation and CXCL10 in recent-onset type 1 diabetes.

Roep BO, Kleijwegt FS, van Halteren AG, Bonato V, Boggi U, Vendrame F, Marchetti P, Dotta F.

Clin Exp Immunol. 2010 Mar;159(3):338-43. doi: 10.1111/j.1365-2249.2009.04087.x. Epub 2010 Jan 5.


Naturally acquired tolerance and sensitization to minor histocompatibility antigens in healthy family members.

van Halteren AG, Jankowska-Gan E, Joosten A, Blokland E, Pool J, Brand A, Burlingham WJ, Goulmy E.

Blood. 2009 Sep 10;114(11):2263-72. doi: 10.1182/blood-2009-01-200410. Epub 2009 Jun 8.


Association of HY-restricting HLA class II alleles with pregnancy outcome in patients with recurrent miscarriage subsequent to a firstborn boy.

Nielsen HS, Steffensen R, Varming K, Van Halteren AG, Spierings E, Ryder LP, Goulmy E, Christiansen OB.

Hum Mol Genet. 2009 May 1;18(9):1684-91. doi: 10.1093/hmg/ddp077. Epub 2009 Feb 17.


TAP-inhibiting proteins US6, ICP47 and UL49.5 differentially affect minor and major histocompatibility antigen-specific recognition by cytotoxic T lymphocytes.

Oosten LE, Koppers-Lalic D, Blokland E, Mulder A, Ressing ME, Mutis T, van Halteren AG, Wiertz EJ, Goulmy E.

Int Immunol. 2007 Sep;19(9):1115-22.


Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.

Dotta F, Censini S, van Halteren AG, Marselli L, Masini M, Dionisi S, Mosca F, Boggi U, Muda AO, Del Prato S, Elliott JF, Covacci A, Rappuoli R, Roep BO, Marchetti P.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5115-20. Epub 2007 Mar 14.


Promiscuity of the AlloHLA-A2 restricted T cell repertoire hampers the generation of minor Histocompatibility antigen-specific cytotoxic T cells across HLA barriers.

Oosten LE, Blokland E, Kester MG, Falkenburg JH, van Halteren AG, Goulmy E.

Biol Blood Marrow Transplant. 2007 Feb;13(2):151-63.


Adult and cord blood T cells can acquire HA-1 specificity through HA-1 T-cell receptor gene transfer.

Mommaas B, van Halteren AG, Pool J, van der Veken L, Wieles B, Heemskerk MH, Goulmy E.

Haematologica. 2005 Oct;90(10):1415-21.


Investigation of peptide involvement in T cell allorecognition using recombinant HLA class I multimers.

Whitelegg AM, Oosten LE, Jordan S, Kester M, van Halteren AG, Madrigal JA, Goulmy E, Barber LD.

J Immunol. 2005 Aug 1;175(3):1706-14.


Homing of human autoreactive T cells into pancreatic tissue of NOD-scid mice.

van Halteren AG, Kardol MJ, Mulder A, Roep BO.

Diabetologia. 2005 Jan;48(1):75-82. Epub 2004 Dec 24.


1alpha,25-dihydroxyvitamin D3 or analogue treated dendritic cells modulate human autoreactive T cells via the selective induction of apoptosis.

van Halteren AG, Tysma OM, van Etten E, Mathieu C, Roep BO.

J Autoimmun. 2004 Nov;23(3):233-9.


Cord blood comprises antigen-experienced T cells specific for maternal minor histocompatibility antigen HA-1.

Mommaas B, Stegehuis-Kamp JA, van Halteren AG, Kester M, Enczmann J, Wernet P, Kögler G, Mutis T, Brand A, Goulmy E.

Blood. 2005 Feb 15;105(4):1823-7. Epub 2004 Oct 21.


Artificial antigen-presenting constructs efficiently stimulate minor histocompatibility antigen-specific cytotoxic T lymphocytes.

Oosten LE, Blokland E, van Halteren AG, Curtsinger J, Mescher MF, Falkenburg JH, Mutis T, Goulmy E.

Blood. 2004 Jul 1;104(1):224-6. Epub 2004 Mar 18.


Pregnancy induces minor histocompatibility antigen-specific cytotoxic T cells: implications for stem cell transplantation and immunotherapy.

Verdijk RM, Kloosterman A, Pool J, van de Keur M, Naipal AM, van Halteren AG, Brand A, Mutis T, Goulmy E.

Blood. 2004 Mar 1;103(5):1961-4. Epub 2003 Oct 30.


Nasal tolerance induces antigen-specific CD4+CD25- regulatory T cells that can transfer their regulatory capacity to naive CD4+ T cells.

Unger WW, Jansen W, Wolvers DA, van Halteren AG, Kraal G, Samsom JN.

Int Immunol. 2003 Jun;15(6):731-9.


Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells.

Greening JE, Tree TI, Kotowicz KT, van Halteren AG, Roep BO, Klein NJ, Peakman M.

Diabetes. 2003 Mar;52(3):717-25.


Modulation of autoimmunity to beta-cell antigens by proteases.

Roep BO, van den Engel NK, van Halteren AG, Duinkerken G, Martin S.

Diabetologia. 2002 May;45(5):686-92. Epub 2002 Mar 28.


Redirection of human autoreactive T-cells Upon interaction with dendritic cells modulated by TX527, an analog of 1,25 dihydroxyvitamin D(3).

van Halteren AG, van Etten E, de Jong EC, Bouillon R, Roep BO, Mathieu C.

Diabetes. 2002 Jul;51(7):2119-25.


Cross-reactive mycobacterial and self hsp60 epitope recognition in I-A(g7) expressing NOD, NOD-asp and Biozzi AB/H mice.

van Halteren AG, Roep BO, Gregori S, Cooke A, van Eden W, Kraal G, Wauben MH.

J Autoimmun. 2002 Mar;18(2):139-47.


T cell reactivity to heat shock protein 60 in diabetes-susceptible and genetically protected nonobese diabetic mice is associated with a protective cytokine profile.

van Halteren AG, Mosselman B, Roep BO, van Eden W, Cooke A, Kraal G, Wauben MH.

J Immunol. 2000 Nov 15;165(10):5544-51.


Regulation of antigen-specific IgE, IgG1, and mast cell responses to ingested allergen by mucosal tolerance induction.

van Halteren AG, van der Cammen MJ, Cooper D, Savelkoul HF, Kraal G, Holt PG.

J Immunol. 1997 Sep 15;159(6):3009-15.


IgE and mast cell response on intestinal allergen exposure: a murine model to study the onset of food allergy.

van Halteren AG, van der Cammen MJ, Biewenga J, Savelkoul HF, Kraal G.

J Allergy Clin Immunol. 1997 Jan;99(1 Pt 1):94-9.


The presence of peptidoglycan-polysaccharide complexes in the bowel wall and the cellular responses to these complexes in Crohn's disease.

Klasen IS, Melief MJ, van Halteren AG, Schouten WR, van Blankenstein M, Hoke G, de Visser H, Hooijkaas H, Hazenberg MP.

Clin Immunol Immunopathol. 1994 Jun;71(3):303-8.


Vascular addressin expression in Peyer's patches: an in vivo study of site-associated regulation.

van Halteren AG, Mebius RE, Kraal G.

Adv Exp Med Biol. 1994;355:125-30. No abstract available.


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