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Items: 1 to 50 of 103


A novel bispecific antibody for EGFR-directed blockade of the PD-1/PD-L1 immune checkpoint.

Koopmans I, Hendriks D, Samplonius DF, van Ginkel RJ, Heskamp S, Wierstra PJ, Bremer E, Helfrich W.

Oncoimmunology. 2018 May 31;7(8):e1466016. doi: 10.1080/2162402X.2018.1466016. eCollection 2018.


Moving beyond panaceas in fisheries governance.

Young OR, Webster DG, Cox ME, Raakjær J, Blaxekjær LØ, Einarsson N, Virginia RA, Acheson J, Bromley D, Cardwell E, Carothers C, Eythórsson E, Howarth RB, Jentoft S, McCay BJ, McCormack F, Osherenko G, Pinkerton E, van Ginkel R, Wilson JA, Rivers L 3rd, Wilson RS.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9065-9073. doi: 10.1073/pnas.1716545115. Epub 2018 Aug 23.


Pelvic lymph node dissection in metastatic melanoma to the groin should not be abandoned yet.

Faut M, Kruijff S, Hoekstra HJ, van Ginkel RJ, Been LB, van Leeuwen BL.

Eur J Surg Oncol. 2018 Jul 7. pii: S0748-7983(18)31175-2. doi: 10.1016/j.ejso.2018.06.031. [Epub ahead of print]


Risk factors for persisting measles susceptibility: a case-control study among unvaccinated orthodox Protestants.

de Munter AC, Tostmann A, Hahné SJM, Spaan DH, van Ginkel R, Ruijs WLM.

Eur J Public Health. 2018 Apr 30. doi: 10.1093/eurpub/cky072. [Epub ahead of print]


Hyperthermic isolated limb perfusion, preoperative radiotherapy, and surgery (PRS) a new limb saving treatment strategy for locally advanced sarcomas.

Stevenson MG, Seinen JM, Pras E, Brouwers AH, van Ginkel RJ, van Leeuwen BL, Suurmeijer AJH, Been LB, Hoekstra HJ.

J Surg Oncol. 2018 Jun;117(7):1447-1454. doi: 10.1002/jso.25008. Epub 2018 Feb 26.


CD20-selective inhibition of CD47-SIRPα "don't eat me" signaling with a bispecific antibody-derivative enhances the anticancer activity of daratumumab, alemtuzumab and obinutuzumab.

van Bommel PE, He Y, Schepel I, Hendriks MAJM, Wiersma VR, van Ginkel RJ, van Meerten T, Ammatuna E, Huls G, Samplonius DF, Helfrich W, Bremer E.

Oncoimmunology. 2017 Oct 31;7(2):e1386361. doi: 10.1080/2162402X.2017.1386361. eCollection 2018.


Reply to comment on: Incidence and predictors of postoperative delirium after cytoreduction surgery-hyperthermic intraperitoneal chemotherapy.

Plas M, Hemmer PHJ, Been LB, van Ginkel RJ, de Bock GH, van Leeuwen BL.

J Surg Oncol. 2018 Mar;117(4):808. doi: 10.1002/jso.24914. Epub 2017 Dec 11. No abstract available.


The reciprocal relationship between daily fatigue and catastrophizing following cancer treatment: Affect and physical activity as potential mediators.

Müller F, Stephenson E, DeLongis A, Smink A, Van Ginkel RJ, Tuinman MA, Hagedoorn M.

Psychooncology. 2018 Mar;27(3):831-837. doi: 10.1002/pon.4574. Epub 2017 Nov 23.


Incidence and predictors of postoperative delirium after cytoreduction surgery-hyperthermic intraperitoneal chemotherapy.

Plas M, Hemmer PHJ, Been LB, van Ginkel RJ, de Bock GH, van Leeuwen BL.

J Surg Oncol. 2018 Feb;117(2):260-268. doi: 10.1002/jso.24811. Epub 2017 Sep 20.


Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin: a single-centre feasibility study.

Harlaar NJ, Koller M, de Jongh SJ, van Leeuwen BL, Hemmer PH, Kruijff S, van Ginkel RJ, Been LB, de Jong JS, Kats-Ugurlu G, Linssen MD, Jorritsma-Smit A, van Oosten M, Nagengast WB, Ntziachristos V, van Dam GM.

Lancet Gastroenterol Hepatol. 2016 Dec;1(4):283-290. doi: 10.1016/S2468-1253(16)30082-6. Epub 2016 Sep 17.


Assessment of Volumetric versus Manual Measurement in Disseminated Testicular Cancer; No Difference in Assessment between Non-Radiologists and Genitourinary Radiologist.

Öztürk Ç, Velleman T, Bongaerts AH, Bergman LM, van Ginkel RJ, Gietema JA, Hoekstra HJ.

PLoS One. 2017 Jan 12;12(1):e0168977. doi: 10.1371/journal.pone.0168977. eCollection 2017.


Nodular Histologic Subtype and Ulceration are Tumor Factors Associated with High Risk of Recurrence in Sentinel Node-Negative Melanoma Patients.

Faut M, Wevers KP, van Ginkel RJ, Diercks GF, Hoekstra HJ, Kruijff S, Been LB, van Leeuwen BL.

Ann Surg Oncol. 2017 Jan;24(1):142-149. doi: 10.1245/s10434-016-5566-8. Epub 2016 Sep 19.


Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction.

Hendriks D, He Y, Koopmans I, Wiersma VR, van Ginkel RJ, Samplonius DF, Helfrich W, Bremer E.

Oncoimmunology. 2016 Jul 6;5(8):e1202390. doi: 10.1080/2162402X.2016.1202390. eCollection 2016 Aug.


Morbidity After Inguinal Lymph Node Dissections: It Is Time for a Change.

Faut M, Heidema RM, Hoekstra HJ, van Ginkel RJ, Been SL, Kruijff S, van Leeuwen BL.

Ann Surg Oncol. 2017 Feb;24(2):330-339. doi: 10.1245/s10434-016-5461-3. Epub 2016 Aug 12.


Melanoma-Directed Activation of Apoptosis Using a Bispecific Antibody Directed at MCSP and TRAIL Receptor-2/Death Receptor-5.

He Y, Hendriks D, van Ginkel R, Samplonius D, Bremer E, Helfrich W.

J Invest Dermatol. 2016 Feb;136(2):541-4. doi: 10.1016/j.jid.2015.11.009. Epub 2015 Dec 2. No abstract available.


Cytoreduction and hyperthermic intraperitoneal chemotherapy: The learning curve reassessed.

Kuijpers AM, Hauptmann M, Aalbers AG, Nienhuijs SW, de Hingh IH, Wiezer MJ, van Ramshorst B, van Ginkel RJ, Havenga K, Verwaal VJ.

Eur J Surg Oncol. 2016 Feb;42(2):244-50. doi: 10.1016/j.ejso.2015.08.162. Epub 2015 Sep 3.


The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux.

Wiersma VR, de Bruyn M, Wei Y, van Ginkel RJ, Hirashima M, Niki T, Nishi N, Zhou J, Pouwels SD, Samplonius DF, Nijman HW, Eggleton P, Helfrich W, Bremer E.

Autophagy. 2015;11(8):1373-88. doi: 10.1080/15548627.2015.1063767.


Adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colon cancer at high risk of peritoneal carcinomatosis; the COLOPEC randomized multicentre trial.

Klaver CE, Musters GD, Bemelman WA, Punt CJ, Verwaal VJ, Dijkgraaf MG, Aalbers AG, van der Bilt JD, Boerma D, Bremers AJ, Burger JW, Buskens CJ, Evers P, van Ginkel RJ, van Grevenstein WM, Hemmer PH, de Hingh IH, Lammers LA, van Leeuwen BL, Meijerink WJ, Nienhuijs SW, Pon J, Radema SA, van Ramshorst B, Snaebjornsson P, Tuynman JB, Te Velde EA, Wiezer MJ, de Wilt JH, Tanis PJ.

BMC Cancer. 2015 May 24;15:428. doi: 10.1186/s12885-015-1430-7.


Implementation of a standardized HIPEC protocol improves outcome for peritoneal malignancy.

Kuijpers AM, Aalbers AG, Nienhuijs SW, de Hingh IH, Wiezer MJ, van Ramshorst B, van Ginkel RJ, Havenga K, Heemsbergen WD, Hauptmann M, Verwaal VJ.

World J Surg. 2015 Feb;39(2):453-60. doi: 10.1007/s00268-014-2801-y.


Paralytic shellfish toxins, including deoxydecarbamoyl-STX, in wild-caught Tasmanian abalone (Haliotis rubra).

Harwood DT, Selwood AI, van Ginkel R, Waugh C, McNabb PS, Munday R, Hay B, Thomas K, Quilliam MA, Malhi N, Dowsett N, McLeod C.

Toxicon. 2014 Nov;90:213-25. doi: 10.1016/j.toxicon.2014.08.058. Epub 2014 Aug 23.


Deep lymph node metastases in the groin significantly affects prognosis, particularly in sentinel node-positive melanoma patients.

Niebling MG, Wevers KP, Suurmeijer AJ, van Ginkel RJ, Hoekstra HJ.

Ann Surg Oncol. 2015 Jan;22(1):279-86. doi: 10.1245/s10434-014-3854-8. Epub 2014 Jul 10.


In vitro labelling of muscle type nicotinic receptors using a fluorophore-conjugated pinnatoxin F derivative.

Hellyer SD, Selwood AI, van Ginkel R, Munday R, Sheard P, Miles CO, Rhodes L, Kerr DS.

Toxicon. 2014 Sep;87:17-25. doi: 10.1016/j.toxicon.2014.05.013. Epub 2014 Jun 2.


Giant adrenal myelolipoma: when trauma and oncology collide.

Zorgdrager M, Pol R, van Hemel B, van Ginkel R.

BMJ Case Rep. 2014 May 28;2014. pii: bcr2014204023. doi: 10.1136/bcr-2014-204023.


Climate change and public health policy: translating the science.

Braks M, van Ginkel R, Wint W, Sedda L, Sprong H.

Int J Environ Res Public Health. 2013 Dec 19;11(1):13-29. doi: 10.3390/ijerph110100013. Review.


Isolated limb perfusion for in-transit melanoma metastases: melphalan or TNF-melphalan perfusion?

Hoekstra HJ, Veerman K, van Ginkel RJ.

J Surg Oncol. 2014 Mar;109(4):338-47. doi: 10.1002/jso.23552. Epub 2014 Jan 9. Review.


A CD47-blocking TRAIL fusion protein with dual pro-phagocytic and pro-apoptotic anticancer activity.

Wiersma VR, He Y, Samplonius DF, van Ginkel RJ, Gerssen J, Eggleton P, Zhou J, Bremer E, Helfrich W.

Br J Haematol. 2014 Jan;164(2):304-7. doi: 10.1111/bjh.12617. Epub 2013 Oct 26. No abstract available.


Cytoreduction and HIPEC in the Netherlands: nationwide long-term outcome following the Dutch protocol.

Kuijpers AM, Mirck B, Aalbers AG, Nienhuijs SW, de Hingh IH, Wiezer MJ, van Ramshorst B, van Ginkel RJ, Havenga K, Bremers AJ, de Wilt JH, Te Velde EA, Verwaal VJ.

Ann Surg Oncol. 2013 Dec;20(13):4224-30. doi: 10.1245/s10434-013-3145-9. Epub 2013 Jul 30.


[Limb perfusion in soft tissue sarcomas: twenty years of experience].

Hoven-Gondrie ML, Bastiaannet E, van Ginkel RJ, Pras EB, Suurmeijer A, Hoekstra HJ.

Ned Tijdschr Geneeskd. 2013;157(30):A6148. Dutch.


Hypoglycemia in a patient with a big "big"-IGF-II-producing tumor.

Alkemade GM, Bakker M, Rikhof B, IJpma FF, van Ginkel RJ, Kluin PM, van Doorn J, Dullaart RP.

J Clin Endocrinol Metab. 2013 Aug;98(8):3113-4. doi: 10.1210/jc.2013-2170. Epub 2013 Jun 20. No abstract available.


Galectin-9 activates and expands human T-helper 1 cells.

Gooden MJ, Wiersma VR, Samplonius DF, Gerssen J, van Ginkel RJ, Nijman HW, Hirashima M, Niki T, Eggleton P, Helfrich W, Bremer E.

PLoS One. 2013 May 31;8(5):e65616. doi: 10.1371/journal.pone.0065616. Print 2013.


Early mobilization after ilio-inguinal lymph node dissection for melanoma does not increase the wound complication rate.

Wevers KP, Poos HP, van Ginkel RJ, van Etten B, Hoekstra HJ.

Eur J Surg Oncol. 2013 Feb;39(2):185-90. doi: 10.1016/j.ejso.2012.08.018. Epub 2012 Sep 13.


Determination of brevetoxins in shellfish by LC/MS/MS: single-laboratory validation.

McNabb PS, Selwood AI, Van Ginkel R, Boundy M, Holland PT.

J AOAC Int. 2012 Jul-Aug;95(4):1097-105.


Cutaneous leiomyosarcoma arising in a smallpox scar.

Pol RA, Dannenberg H, Robertus JL, van Ginkel RJ.

World J Surg Oncol. 2012 Jul 16;10:148. doi: 10.1186/1477-7819-10-148.


A sensitive assay for palytoxins, ovatoxins and ostreocins using LC-MS/MS analysis of cleavage fragments from micro-scale oxidation.

Selwood AI, van Ginkel R, Harwood DT, McNabb PS, Rhodes LR, Holland PT.

Toxicon. 2012 Oct;60(5):810-20. doi: 10.1016/j.toxicon.2012.05.024. Epub 2012 May 31.


Therapeutic lymph node dissection in melanoma: different prognosis for different macrometastasis sites?

Wevers KP, Bastiaannet E, Poos HP, van Ginkel RJ, Plukker JT, Hoekstra HJ.

Ann Surg Oncol. 2012 Nov;19(12):3913-8. doi: 10.1245/s10434-012-2401-8. Epub 2012 May 17.


The glycan-binding protein galectin-9 has direct apoptotic activity toward melanoma cells.

Wiersma VR, de Bruyn M, van Ginkel RJ, Sigar E, Hirashima M, Niki T, Nishi N, Samplonius DF, Helfrich W, Bremer E.

J Invest Dermatol. 2012 Sep;132(9):2302-5. doi: 10.1038/jid.2012.133. Epub 2012 May 10. No abstract available.


Toxicity thresholds for juvenile freshwater mussels Echyridella menziesii and crayfish Paranephrops planifrons, after acute or chronic exposure to Microcystis sp.

Clearwater SJ, Wood SA, Phillips NR, Parkyn SM, Van Ginkel R, Thompson KJ.

Environ Toxicol. 2014 May;29(5):487-502. doi: 10.1002/tox.21774. Epub 2012 Apr 4.


Laparoscopic resection of a residual retroperitoneal tumor mass of nonseminomatous testicular germ cell tumors.

Oztürk C, van Ginkel RJ, Krol RM, Gietema JA, Hofker HS, Hoekstra HJ.

Surg Endosc. 2012 Feb;26(2):458-67. doi: 10.1007/s00464-011-1901-0. Epub 2011 Sep 23.


Uptake, distribution and depuration of paralytic shellfish toxins from Alexandrium minutum in Australian greenlip abalone, Haliotis laevigata.

Dowsett N, Hallegraeff G, van Ruth P, van Ginkel R, McNabb P, Hay B, O'Connor W, Kiermeier A, Deveney M, McLeod C.

Toxicon. 2011 Jul;58(1):101-11. doi: 10.1016/j.toxicon.2011.05.010. Epub 2011 May 27.


Long-term follow-up reveals that ulceration and sentinel lymph node status are the strongest predictors for survival in patients with primary cutaneous melanoma.

de Vries M, Speijers MJ, Bastiaannet E, Plukker JT, Brouwers AH, van Ginkel RJ, Suurmeijer AJ, Hoekstra HJ.

Eur J Surg Oncol. 2011 Aug;37(8):681-7. doi: 10.1016/j.ejso.2011.05.003. Epub 2011 Jun 1.


TNF dose reduction and shortening of duration of isolated limb perfusion for locally advanced soft tissue sarcoma of the extremities is safe and effective in terms of long-term patient outcome.

Hoven-Gondrie ML, Bastiaannet E, van Ginkel RJ, Suurmeijer AJ, Hoekstra HJ.

J Surg Oncol. 2011 Jun 1;103(7):648-55. doi: 10.1002/jso.21885. Epub 2011 Feb 17.


First report of saxitoxin production by a species of the freshwater benthic cyanobacterium, Scytonema Agardh.

Smith FM, Wood SA, van Ginkel R, Broady PA, Gaw S.

Toxicon. 2011 Mar 15;57(4):566-73. doi: 10.1016/j.toxicon.2010.12.020. Epub 2011 Jan 9.


Approach and management of primary ectopic breast carcinoma in the axilla: where are we? A comprehensive historical literature review.

Visconti G, Eltahir Y, Van Ginkel RJ, Bart J, Werker PM.

J Plast Reconstr Aesthet Surg. 2011 Jan;64(1):e1-11. doi: 10.1016/j.bjps.2010.08.015. Epub 2010 Oct 12. Review.


FDG-PET probe-guided surgery for recurrent retroperitoneal testicular tumor recurrences.

de Jong JS, van Ginkel RJ, Slart RH, Lemstra CL, Paans AM, Mulder NH, Hoekstra HJ.

Eur J Surg Oncol. 2010 Nov;36(11):1092-5. doi: 10.1016/j.ejso.2010.08.129. Epub 2010 Sep 15.


Detection of tetrodotoxin from the grey side-gilled sea slug - Pleurobranchaea maculata, and associated dog neurotoxicosis on beaches adjacent to the Hauraki Gulf, Auckland, New Zealand.

McNabb P, Selwood AI, Munday R, Wood SA, Taylor DI, Mackenzie LA, van Ginkel R, Rhodes LL, Cornelisen C, Heasman K, Holland PT, King C.

Toxicon. 2010 Sep 1;56(3):466-73. doi: 10.1016/j.toxicon.2010.04.017. Epub 2010 May 11.


Isolation, structural determination and acute toxicity of pinnatoxins E, F and G.

Selwood AI, Miles CO, Wilkins AL, van Ginkel R, Munday R, Rise F, McNabb P.

J Agric Food Chem. 2010 May 26;58(10):6532-42. doi: 10.1021/jf100267a.


Bioassay methods for detection of N-palmitoylbrevetoxin-B2 (BTX-B4).

Bottein MY, Fuquay JM, Munday R, Selwood AI, van Ginkel R, Miles CO, Loader JI, Wilkins AL, Ramsdell JS.

Toxicon. 2010 Feb-Mar;55(2-3):497-506. doi: 10.1016/j.toxicon.2009.09.022. Epub 2009 Oct 9.


Dermatofibrosarcoma protuberans: recurrence is related to the adequacy of surgical margins.

Heuvel ST, Suurmeijer A, Pras E, Van Ginkel RJ, Hoekstra HJ.

Eur J Surg Oncol. 2010 Jan;36(1):89-94. doi: 10.1016/j.ejso.2009.07.006. Epub 2009 Jul 31.


S-100B concentrations predict disease-free survival in stage III melanoma patients.

Kruijff S, Bastiaannet E, Kobold AC, van Ginkel RJ, Suurmeijer AJ, Hoekstra HJ.

Ann Surg Oncol. 2009 Dec;16(12):3455-62. doi: 10.1245/s10434-009-0629-8. Erratum in: Ann Surg Oncol. 2011 Dec;18 Suppl 3:S331.


Anatomy of phobanes. diastereoselective synthesis of the three isomers of n-butylphobane and a comparison of their donor properties.

Carreira M, Charernsuk M, Eberhard M, Fey N, van Ginkel R, Hamilton A, Mul WP, Orpen AG, Phetmung H, Pringle PG.

J Am Chem Soc. 2009 Mar 4;131(8):3078-92. doi: 10.1021/ja808807s.


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