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Items: 41

1.

Development of a non-human primate model to support CNS translational research: Demonstration with D-amphetamine exposure and dopamine response.

Folgering JH, Choi M, Schlumbohm C, van Gaalen MM, Stratford RE Jr.

J Neurosci Methods. 2019 Feb 12;317:71-81. doi: 10.1016/j.jneumeth.2019.02.005. [Epub ahead of print]

2.

Mechanism-Based Pharmacokinetic-Pharmacodynamic Model Describing Dextroamphetamine Exposure and Striatal Dopamine Response in Rats and Non-Human Primates following a Single Intravenous Dose of Dextroamphetamine.

van Gaalen M, Schlumbohm C, Folgering J, Adhikari S, Bhattacharya C, Steinbach D, Stratford RE.

J Pharmacol Exp Ther. 2019 Feb 7. pii: jpet.118.254508. doi: 10.1124/jpet.118.254508. [Epub ahead of print]

3.

Novel, potent, selective and brain penetrant vasopressin 1b receptor antagonists.

Geneste H, Bhowmik S, van Gaalen MM, Hornberger W, Hutchins CW, Netz A, Oost T, Unger L.

Bioorg Med Chem Lett. 2018 Oct 15;28(19):3260-3264. doi: 10.1016/j.bmcl.2018.07.043. Epub 2018 Jul 31.

PMID:
30098866
4.

Self-efficacy did not predict the outcome of the transition to adult care in adolescents with inflammatory bowel disease.

van den Brink G, van Gaalen MAC, Zijlstra M, de Ridder L, van der Woude CJ, Escher JC.

Acta Paediatr. 2019 Feb;108(2):333-338. doi: 10.1111/apa.14471. Epub 2018 Jul 10.

PMID:
29926962
5.

[Transition from paediatric to adult care: management of adolescents with inflammatory bowel disease].

van den Brink G, van der Woude CJ, de Ridder L, van Gaalen MA, Escher JC.

Ned Tijdschr Geneeskd. 2016;160:D578. Dutch.

PMID:
27581867
6.

Environmental and Pharmacological Modulation of Amphetamine- Induced 50-kHz Ultrasonic Vocalizations in Rats.

Rippberger H, van Gaalen MM, Schwarting RK, Wohr M.

Curr Neuropharmacol. 2015;13(2):220-32. Review.

7.

Affective communication in rodents: serotonin and its modulating role in ultrasonic vocalizations.

Wöhr M, van Gaalen MM, Schwarting RK.

Behav Pharmacol. 2015 Sep;26(6):506-21. doi: 10.1097/FBP.0000000000000172. Review.

PMID:
26221830
8.

The Vasopressin 1b Receptor Antagonist A-988315 Blocks Stress Effects on the Retrieval of Object-Recognition Memory.

Barsegyan A, Atsak P, Hornberger WB, Jacobson PB, van Gaalen MM, Roozendaal B.

Neuropsychopharmacology. 2015 Jul;40(8):1979-89. doi: 10.1038/npp.2015.48. Epub 2015 Feb 11.

9.

Critical involvement of 5-HT2C receptor function in amphetamine-induced 50-kHz ultrasonic vocalizations in rats.

Wöhr M, Rippberger H, Schwarting RK, van Gaalen MM.

Psychopharmacology (Berl). 2015 May;232(10):1817-29. doi: 10.1007/s00213-014-3814-9. Epub 2014 Nov 25.

PMID:
25417553
10.

NOGO-66 receptor deficient mice show slow acquisition of spatial memory task performance.

van Gaalen MM, Relo AL, Mueller BK, Gross G, Mezler M.

Neurosci Lett. 2012 Feb 21;510(1):58-61. doi: 10.1016/j.neulet.2012.01.004. Epub 2012 Jan 11.

PMID:
22260793
11.

On the improvement of inhibitory response control and visuospatial attention by indirect and direct adrenoceptor agonists.

Pattij T, Schetters D, Schoffelmeer AN, van Gaalen MM.

Psychopharmacology (Berl). 2012 Jan;219(2):327-40. doi: 10.1007/s00213-011-2405-2. Epub 2011 Jul 19.

12.

Potent and selective oxindole-based vasopressin 1b receptor antagonists with improved pharmacokinetic properties.

Oost T, Backfisch G, Bhowmik S, van Gaalen MM, Geneste H, Hornberger W, Lubisch W, Netz A, Unger L, Wernet W.

Bioorg Med Chem Lett. 2011 Jun 15;21(12):3828-31. doi: 10.1016/j.bmcl.2011.03.012. Epub 2011 Mar 6.

PMID:
21605973
13.

Reduced spine density in specific regions of CA1 pyramidal neurons in two transgenic mouse models of Alzheimer's disease.

Perez-Cruz C, Nolte MW, van Gaalen MM, Rustay NR, Termont A, Tanghe A, Kirchhoff F, Ebert U.

J Neurosci. 2011 Mar 9;31(10):3926-34. doi: 10.1523/JNEUROSCI.6142-10.2011.

14.

Antidepressant treatment in anxiety disorders.

Bespalov AY, van Gaalen MM, Gross G.

Curr Top Behav Neurosci. 2010;2:361-90. Review.

PMID:
21309117
15.

Effects of a positive allosteric modulator of group II metabotropic glutamate receptors, LY487379, on cognitive flexibility and impulsive-like responding in rats.

Nikiforuk A, Popik P, Drescher KU, van Gaalen M, Relo AL, Mezler M, Marek G, Schoemaker H, Gross G, Bespalov A.

J Pharmacol Exp Ther. 2010 Dec;335(3):665-73. doi: 10.1124/jpet.110.170506. Epub 2010 Aug 25.

PMID:
20739457
16.

Generation and therapeutic efficacy of highly oligomer-specific beta-amyloid antibodies.

Hillen H, Barghorn S, Striebinger A, Labkovsky B, Müller R, Nimmrich V, Nolte MW, Perez-Cruz C, van der Auwera I, van Leuven F, van Gaalen M, Bespalov AY, Schoemaker H, Sullivan JP, Ebert U.

J Neurosci. 2010 Aug 4;30(31):10369-79. doi: 10.1523/JNEUROSCI.5721-09.2010.

17.

5-HT6 antagonism attenuates cue-induced relapse to cocaine seeking without affecting cocaine reinforcement.

van Gaalen MM, Schetters D, Schoffelmeer AN, De Vries TJ.

Int J Neuropsychopharmacol. 2010 Aug;13(7):961-5. doi: 10.1017/S1461145710000428. Epub 2010 Apr 29.

PMID:
20426879
18.

Amphetamine decreases behavioral inhibition by stimulation of dopamine D2, but not D3, receptors.

van Gaalen MM, Unger L, Jongen-Rêlo AL, Schoemaker H, Gross G.

Behav Pharmacol. 2009 Sep;20(5-6):484-91. doi: 10.1097/FBP.0b013e3283305e3b.

PMID:
19696659
19.

Dopamine receptor D1/D5 gene expression in the medial prefrontal cortex predicts impulsive choice in rats.

Loos M, Pattij T, Janssen MC, Counotte DS, Schoffelmeer AN, Smit AB, Spijker S, van Gaalen MM.

Cereb Cortex. 2010 May;20(5):1064-70. doi: 10.1093/cercor/bhp167. Epub 2009 Aug 18.

PMID:
19690230
20.

SSR149415, a non-peptide vasopressin V1b receptor antagonist, has long-lasting antidepressant effects in the olfactory bulbectomy-induced hyperactivity depression model.

Breuer ME, van Gaalen MM, Wernet W, Claessens SE, Oosting RS, Behl B, Korte SM, Schoemaker H, Gross G, Olivier B, Groenink L.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Jan;379(1):101-6. doi: 10.1007/s00210-008-0336-1. Epub 2008 Jul 31.

PMID:
18668225
21.

Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression.

Bespalov AY, van Gaalen MM, Sukhotina IA, Wicke K, Mezler M, Schoemaker H, Gross G.

Eur J Pharmacol. 2008 Sep 11;592(1-3):96-102. doi: 10.1016/j.ejphar.2008.06.089. Epub 2008 Jul 2.

PMID:
18634781
22.

AMPA receptor antagonists reverse effects of extended habit training on signaled food approach responding in rats.

Bespalov AY, Harich S, Jongen-Rêlo AL, van Gaalen MM, Gross G.

Psychopharmacology (Berl). 2007 Nov;195(1):11-8. Epub 2007 Jul 19.

PMID:
17634927
23.

Habituation deficits induced by metabotropic glutamate receptors 2/3 receptor blockade in mice: reversal by antipsychotic drugs.

Bespalov A, Jongen-Rêlo AL, van Gaalen M, Harich S, Schoemaker H, Gross G.

J Pharmacol Exp Ther. 2007 Feb;320(2):944-50. Epub 2006 Nov 29.

PMID:
17135347
24.

Strain specificity and cholinergic modulation of visuospatial attention in three inbred mouse strains.

Pattij T, Janssen MC, Loos M, Smit AB, Schoffelmeer AN, van Gaalen MM.

Genes Brain Behav. 2007 Aug;6(6):579-87. Epub 2006 Nov 17.

25.

Involvement of dopamine D1 and D2 receptors in the nucleus accumbens core and shell in inhibitory response control.

Pattij T, Janssen MC, Vanderschuren LJ, Schoffelmeer AN, van Gaalen MM.

Psychopharmacology (Berl). 2007 Apr;191(3):587-98. Epub 2006 Sep 14.

PMID:
16972104
26.

Behavioral disinhibition requires dopamine receptor activation.

van Gaalen MM, Brueggeman RJ, Bronius PF, Schoffelmeer AN, Vanderschuren LJ.

Psychopharmacology (Berl). 2006 Jul;187(1):73-85. Epub 2006 Apr 25.

PMID:
16767417
27.

Critical involvement of dopaminergic neurotransmission in impulsive decision making.

van Gaalen MM, van Koten R, Schoffelmeer AN, Vanderschuren LJ.

Biol Psychiatry. 2006 Jul 1;60(1):66-73. Epub 2005 Aug 25.

PMID:
16125144
28.

Mice overexpressing CRH show reduced responsiveness in plasma corticosterone after a5-HT1A receptor challenge.

van Gaalen MM, Reul JH, Gesing A, Stenzel-Poore MP, Holsboer F, Steckler T.

Genes Brain Behav. 2002 Aug;1(3):174-7.

PMID:
12884973
29.

Reduced attention in mice overproducing corticotropin-releasing hormone.

van Gaalen MM, Stenzel-Poore M, Holsboer F, Steckler T.

Behav Brain Res. 2003 Jun 16;142(1-2):69-79.

PMID:
12798267
30.

Effects of transgenic overproduction of CRH on anxiety-like behaviour.

van Gaalen MM, Stenzel-Poore MP, Holsboer F, Steckler T.

Eur J Neurosci. 2002 Jun;15(12):2007-15. Erratum in: Eur J Neurosci 2002 Oct;16(7):1407.

PMID:
12099906
31.

Molecular characterisation of antidepressant effects in the mouse brain using gene expression profiling.

Landgrebe J, Welzl G, Metz T, van Gaalen MM, Ropers H, Wurst W, Holsboer F.

J Psychiatr Res. 2002 May-Jun;36(3):119-29.

PMID:
11886689
32.

Functional analysis of the hexose transporter homologue HXT5 in Saccharomyces cerevisiae.

Diderich JA, Schuurmans JM, Van Gaalen MC, Kruckeberg AL, Van Dam K.

Yeast. 2001 Dec;18(16):1515-24.

33.

Regulation of the hypothalamic-pituitary-adrenocortical system in mice deficient for CRH receptors 1 and 2.

Preil J, Müller MB, Gesing A, Reul JM, Sillaber I, van Gaalen MM, Landgrebe J, Holsboer F, Stenzel-Poore M, Wurst W.

Endocrinology. 2001 Nov;142(11):4946-55.

PMID:
11606463
34.

Co-consumption of sugars or ethanol and glucose in a Saccharomyces cerevisiae strain deleted in the HXK2 gene.

Raamsdonk LM, Diderich JA, Kuiper A, van Gaalen M, Kruckeberg AL, Berden JA, Van Dam K.

Yeast. 2001 Aug;18(11):1023-33. Erratum in: Yeast 2002 Jan 30;19(2):183. Kruckberg AL [corrected to Kruckeberg AL].

35.

Effects of the monoamine oxidase A inhibitor moclobemide on hippocampal plasticity in GR-impaired transgenic mice.

Steckler T, Rammes G, Sauvage M, van Gaalen MM, Weis C, Zieglgänsberger W, Holsboer F.

J Psychiatr Res. 2001 Jan-Feb;35(1):29-42.

PMID:
11287054
36.

Behavioural analysis of four mouse strains in an anxiety test battery.

van Gaalen MM, Steckler T.

Behav Brain Res. 2000 Oct;115(1):95-106.

PMID:
10996412
37.

The locus coeruleus noradrenergic system in the rat brain studied by dual-probe microdialysis.

Van Gaalen M, Kawahara H, Kawahara Y, Westerink BH.

Brain Res. 1997 Jul 18;763(1):56-62.

PMID:
9272828
38.
39.
40.

New evidence for the dimeric nature of NADH:Q oxidoreductase in bovine-heart submitochondrial particles.

van Belzen R, van Gaalen MC, Cuypers PA, Albracht SP.

Biochim Biophys Acta. 1990 Jun 1;1017(2):152-9.

PMID:
2112409
41.

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