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Items: 44

1.

Modulating antibody-dependent cellular cytotoxicity of epidermal growth factor receptor-specific heavy-chain antibodies through hinge engineering.

D'Eall C, Pon RA, Rossotti MA, Krahn N, Spearman M, Callaghan D, van Faassen H, Hussack G, Stetefeld J, Butler M, Durocher Y, Zhang J, Henry KA, Tanha J.

Immunol Cell Biol. 2019 Jan 25. doi: 10.1111/imcb.12238. [Epub ahead of print]

PMID:
30680791
2.

Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phenotypically indistinguishable but immunogenetically distinct.

Henry KA, van Faassen H, Harcus D, Marcil A, Hill JJ, Muyldermans S, Roger MacKenzie C.

Immunogenetics. 2019 Jan 18. doi: 10.1007/s00251-018-01102-9. [Epub ahead of print]

PMID:
30656359
3.

Neutralization of Clostridium difficile toxin B with VHH-Fc fusions targeting the delivery and CROPs domains.

Hussack G, Ryan S, van Faassen H, Rossotti M, MacKenzie CR, Tanha J.

PLoS One. 2018 Dec 12;13(12):e0208978. doi: 10.1371/journal.pone.0208978. eCollection 2018.

4.

Camelid single-domain antibodies raised by DNA immunization are potent inhibitors of EGFR signaling.

Rossotti MA, Henry KA, van Faassen H, Tanha J, Callaghan D, Hussack G, Arbabi-Ghahroudi M, MacKenzie CR.

Biochem J. 2019 Jan 7;476(1):39-50. doi: 10.1042/BCJ20180795.

PMID:
30455372
5.

Towards optimal personalized diet and vitamin supplementation in NET patients.

de Hosson LD, Stelwagen J, Bouma G, Sijtema B, Huitema S, van Faassen HJR, de Bock GH, de Groot DJA, Campmans-Kuijpers MJE, Kema IP, de Vries EGE, Walenkamp AME.

Endocr Relat Cancer. 2018 Mar;25(3):L23-L26. doi: 10.1530/ERC-17-0549. No abstract available.

PMID:
29431642
6.

A Novel Affinity Tag, ABTAG, and Its Application to the Affinity Screening of Single-Domain Antibodies Selected by Phage Display.

Hussack G, Baral TN, Baardsnes J, van Faassen H, Raphael S, Henry KA, Zhang J, MacKenzie CR.

Front Immunol. 2017 Oct 30;8:1406. doi: 10.3389/fimmu.2017.01406. eCollection 2017.

7.

A disulfide-stabilized human VL single-domain antibody library is a source of soluble and highly thermostable binders.

Henry KA, Kandalaft H, Lowden MJ, Rossotti MA, van Faassen H, Hussack G, Durocher Y, Kim DY, Tanha J.

Mol Immunol. 2017 Oct;90:190-196. doi: 10.1016/j.molimm.2017.07.006. Epub 2017 Aug 15.

PMID:
28820969
8.

A Rational Engineering Strategy for Designing Protein A-Binding Camelid Single-Domain Antibodies.

Henry KA, Sulea T, van Faassen H, Hussack G, Purisima EO, MacKenzie CR, Arbabi-Ghahroudi M.

PLoS One. 2016 Sep 15;11(9):e0163113. doi: 10.1371/journal.pone.0163113. eCollection 2016.

9.

Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin.

Haji-Ghassemi O, Gilbert M, Spence J, Schur MJ, Parker MJ, Jenkins ML, Burke JE, van Faassen H, Young NM, Evans SV.

J Biol Chem. 2016 Nov 11;291(46):24085-24095. Epub 2016 Sep 6.

10.

An observational study on disturbed peripheral circadian rhythms in hemodialysis patients.

Russcher M, Chaves I, Lech K, Koch BC, Nagtegaal JE, Dorsman KF, Jong A', Kayser M, van Faassen HM, Kema IP, van der Horst GT, Gaillard CA.

Chronobiol Int. 2015;32(6):848-57. doi: 10.3109/07420528.2015.1048868. Epub 2015 Jun 23.

PMID:
26101944
11.

Targeting surface-layer proteins with single-domain antibodies: a potential therapeutic approach against Clostridium difficile-associated disease.

Kandalaft H, Hussack G, Aubry A, van Faassen H, Guan Y, Arbabi-Ghahroudi M, MacKenzie R, Logan SM, Tanha J.

Appl Microbiol Biotechnol. 2015 Oct;99(20):8549-62. doi: 10.1007/s00253-015-6594-1. Epub 2015 May 5.

12.

High affinity anti-Internalin B VHH antibody fragments isolated from naturally and artificially immunized repertoires.

Gene RW, Kumaran J, Aroche C, van Faassen H, Hall JC, MacKenzie CR, Arbabi-Ghahroudi M.

J Immunol Methods. 2015 Jan;416:29-39. doi: 10.1016/j.jim.2014.10.009. Epub 2014 Nov 8.

PMID:
25450000
13.

Protease-resistant single-domain antibodies inhibit Campylobacter jejuni motility.

Hussack G, Riazi A, Ryan S, van Faassen H, MacKenzie R, Tanha J, Arbabi-Ghahroudi M.

Protein Eng Des Sel. 2014 Jun;27(6):191-8. doi: 10.1093/protein/gzu011. Epub 2014 Apr 16.

PMID:
24742504
14.

Antibody light chain variable domains and their biophysically improved versions for human immunotherapy.

Kim DY, To R, Kandalaft H, Ding W, van Faassen H, Luo Y, Schrag JD, St-Amant N, Hefford M, Hirama T, Kelly JF, MacKenzie R, Tanha J.

MAbs. 2014 Jan-Feb;6(1):219-35. doi: 10.4161/mabs.26844.

15.

Pentavalent single-domain antibodies reduce Campylobacter jejuni motility and colonization in chickens.

Riazi A, Strong PC, Coleman R, Chen W, Hirama T, van Faassen H, Henry M, Logan SM, Szymanski CM, Mackenzie R, Ghahroudi MA.

PLoS One. 2013 Dec 31;8(12):e83928. doi: 10.1371/journal.pone.0083928. eCollection 2013.

16.

Monoclonal antibodies recognizing the surface autolysin IspC of Listeria monocytogenes serotype 4b: epitope localization, kinetic characterization, and cross-reaction studies.

Ronholm J, van Faassen H, MacKenzie R, Zhang Z, Cao X, Lin M.

PLoS One. 2013;8(2):e55098. doi: 10.1371/journal.pone.0055098. Epub 2013 Feb 4.

17.

Disulfide linkage engineering for improving biophysical properties of human VH domains.

Kim DY, Kandalaft H, Ding W, Ryan S, van Faassen H, Hirama T, Foote SJ, MacKenzie R, Tanha J.

Protein Eng Des Sel. 2012 Oct;25(10):581-9. Epub 2012 Aug 30.

PMID:
22942392
18.

A V(L) single-domain antibody library shows a high-propensity to yield non-aggregating binders.

Hussack G, Keklikian A, Alsughayyir J, Hanifi-Moghaddam P, Arbabi-Ghahroudi M, van Faassen H, Hou ST, Sad S, MacKenzie R, Tanha J.

Protein Eng Des Sel. 2012 Jun;25(6):313-8. doi: 10.1093/protein/gzs014. Epub 2012 Apr 6.

PMID:
22490957
19.

Specificity analysis of the C-type lectin from rattlesnake venom, and its selectivity towards Gal- or GalNAc-terminated glycoproteins.

Young NM, van Faassen H, Watson DC, Mackenzie CR.

Glycoconj J. 2011 Aug;28(6):427-35. doi: 10.1007/s10719-011-9342-5. Epub 2011 Jul 30.

PMID:
21805077
20.

Neutralization of Clostridium difficile toxin A with single-domain antibodies targeting the cell receptor binding domain.

Hussack G, Arbabi-Ghahroudi M, van Faassen H, Songer JG, Ng KK, MacKenzie R, Tanha J.

J Biol Chem. 2011 Mar 18;286(11):8961-76. doi: 10.1074/jbc.M110.198754. Epub 2011 Jan 7.

21.

Single-domain antibody-nanoparticles: promising architectures for increased staphylococcus aureus detection specificity and sensitivity.

Ryan S, Kell AJ, van Faassen H, Tay LL, Simard B, MacKenzie R, Gilbert M, Tanha J.

Bioconjug Chem. 2009 Oct 21;20(10):1966-74. doi: 10.1021/bc900332r. Epub 2009 Sep 14.

PMID:
19751063
22.

Pathogen proliferation governs the magnitude but compromises the function of CD8 T cells.

Sad S, Dudani R, Gurnani K, Russell M, van Faassen H, Finlay B, Krishnan L.

J Immunol. 2008 May 1;180(9):5853-61.

23.

Mutation in the Fas pathway impairs CD8+ T cell memory.

Dudani R, Russell M, van Faassen H, Krishnan L, Sad S.

J Immunol. 2008 Mar 1;180(5):2933-41.

24.

Neutrophils play an important role in host resistance to respiratory infection with Acinetobacter baumannii in mice.

van Faassen H, KuoLee R, Harris G, Zhao X, Conlan JW, Chen W.

Infect Immun. 2007 Dec;75(12):5597-608. Epub 2007 Oct 1.

25.
26.

Delayed expansion and contraction of CD8+ T cell response during infection with virulent Salmonella typhimurium.

Luu RA, Gurnani K, Dudani R, Kammara R, van Faassen H, Sirard JC, Krishnan L, Sad S.

J Immunol. 2006 Aug 1;177(3):1516-25.

27.
28.
29.

Cross-reactive antigen is required to prevent erosion of established T cell memory and tumor immunity: a heterologous bacterial model of attrition.

Smith DK, Dudani R, Pedras-Vasconcelos JA, Chapdelaine Y, van Faassen H, Sad S.

J Immunol. 2002 Aug 1;169(3):1197-206.

30.
31.

Preexisting inflammation due to Mycobacterium bovis BCG infection differentially modulates T-cell priming against a replicating or nonreplicating immunogen.

Dudani R, Chapdelaine Y, van Faassen H, Smith DK, Shen H, Krishnan L, Sad S.

Infect Immun. 2002 Apr;70(4):1957-64.

32.

Development of Bacillus thuringiensis CryIC Resistance by Spodoptera exigua (Hubner) (Lepidoptera: Noctuidae).

Moar WJ, Pusztai-Carey M, Van Faassen H, Bosch D, Frutos R, Rang C, Luo K, Adang MJ.

Appl Environ Microbiol. 1995 Jun;61(6):2086-92.

33.

Crystallization and preliminary X-ray diffraction studies of the lepidopteran-specific insecticidal crystal protein CrylA(a).

Borisova S, Grochulski P, van Faassen H, Pusztai-Carey M, Masson L, Cygler M.

J Mol Biol. 1994 Oct 28;243(3):530-2.

PMID:
7966278
34.

Hereditary tyrosinaemia type I: a long-term study of the relationship between the urinary excretions of succinylacetone and delta-aminolevulinic acid.

Schierbeek H, Beukeveld GJ, van Faassen H, van Spronsen FJ, Bijsterveld K, Venekamp-Hoolsema EE, Wolthers BG, Smit GP.

J Inherit Metab Dis. 1993;16(6):1034-40.

PMID:
8127053
35.

The human fumarylacetoacetase gene: characterisation of restriction fragment length polymorphisms and identification of haplotypes in tyrosinemia type 1 and pseudodeficiency.

Rootwelt H, Kvittingen EA, Høie K, Agsteribbe E, Hartog M, van Faassen H, Berger R.

Hum Genet. 1992 May;89(2):229-33.

PMID:
1350265
36.

Hereditary tyrosinemia type I: lack of correlation between clinical findings and amount of immunoreactive fumarylacetoacetase protein.

Kvittingen EA, Rootwelt H, van Dam T, van Faassen H, Berger R.

Pediatr Res. 1992 Jan;31(1):43-6.

PMID:
1594329
37.

Nucleotide sequence of cDNA encoding human fumarylacetoacetase.

Agsteribbe E, van Faassen H, Hartog MV, Reversma T, Taanman JW, Pannekoek H, Evers RF, Welling GM, Berger R.

Nucleic Acids Res. 1990 Apr 11;18(7):1887. No abstract available.

38.

Purification of human liver fumarylacetoacetase using immunoaffinity chromatography.

van Faassen H, van den Berg IE, Berger R.

J Biochem Biophys Methods. 1990 Apr-May;20(4):317-24.

PMID:
2195095
39.

Separation of different forms of S-adenosylmethionine synthetase by fast protein liquid chromatography.

van Faassen H, Berger R.

J Biochem Biophys Methods. 1990 Mar;20(3):189-94.

PMID:
2345265
40.

Tyrosinaemia type I: orthotopic liver transplantation as the only definitive answer to a metabolic as well as an oncological problem.

van Spronsen FJ, Berger R, Smit GP, de Klerk JB, Duran M, Bijleveld CM, van Faassen H, Slooff MJ, Heymans HS.

J Inherit Metab Dis. 1989;12 Suppl 2:339-42. Review. No abstract available.

PMID:
2556611
41.

Type I tyrosinemia: lack of immunologically detectable fumarylacetoacetase enzyme protein in tissues and cell extracts.

Berger R, Van Faassen H, Taanman JW, De Vries H, Agsteribbe E.

Pediatr Res. 1987 Oct;22(4):394-8.

PMID:
3317254
42.

Biochemical studies on the enzymatic deficiencies in hereditary tyrosinemia.

Berger R, van Faassen H, Smith GP.

Clin Chim Acta. 1983 Oct 31;134(1-2):129-41.

PMID:
6652907
43.

Effect of hormones on the development of creatine kinase activity in rat skeletal muscle.

Kloosterboer HJ, van Faassen H, Stoker-De Vries SA, Hommes FA.

Biol Neonate. 1979;35(3-4):156-74.

PMID:
435592
44.

Effect of cyclic nucleotides on weight of gastrocnemius and creatine kinase activity after denervation of muscle in young rats.

Kloosterboer HJ, van Faassen H, Stoker-de Vries SA, Hommes FA.

Biol Neonate. 1979;36(3-4):160-7.

PMID:
226186

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