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Items: 1 to 50 of 86

1.

MenB-4C vaccine induces effective opsonophagocytic killing in children with a complement deficiency.

van den Broek B, van Els CACM, Kuipers B, van Aerde K, Henriet SS, de Groot R, de Jonge M, Langereis JD, van der Flier M.

Clin Exp Immunol. 2019 Sep 5. doi: 10.1111/cei.13368. [Epub ahead of print]

PMID:
31487400
2.

Superior B. pertussis Specific CD4+ T-Cell Immunity Imprinted by Natural Infection.

Lambert EE, Buisman AM, van Els CACM.

Adv Exp Med Biol. 2019 Jul 19. doi: 10.1007/5584_2019_405. [Epub ahead of print]

PMID:
31321753
3.

Prediction and Validation of Immunogenic Domains of Pneumococcal Proteins Recognized by Human CD4+ T Cells.

van de Garde MDB, van Westen E, Poelen MCM, Rots NY, van Els CACM.

Infect Immun. 2019 May 21;87(6). pii: e00098-19. doi: 10.1128/IAI.00098-19. Print 2019 Jun.

4.

Discovery of Salmonella trehalose phospholipids reveals functional convergence with mycobacteria.

Reinink P, Buter J, Mishra VK, Ishikawa E, Cheng TY, Willemsen PTJ, Porwollik S, Brennan PJ, Heinz E, Mayfield JA, Dougan G, van Els CA, Cerundolo V, Napolitani G, Yamasaki S, Minnaard AJ, McClelland M, Moody DB, Van Rhijn I.

J Exp Med. 2019 Apr 1;216(4):757-771. doi: 10.1084/jem.20181812. Epub 2019 Feb 25.

PMID:
30804000
5.

The Human CD4+ T Cell Response against Mumps Virus Targets a Broadly Recognized Nucleoprotein Epitope.

de Wit J, Emmelot ME, Poelen MCM, Lanfermeijer J, Han WGH, van Els CACM, Kaaijk P.

J Virol. 2019 Mar 5;93(6). pii: e01883-18. doi: 10.1128/JVI.01883-18. Print 2019 Mar 15.

6.

Serotype-Specific IgG Antibody Waning after Pneumococcal Conjugate Primary Series Vaccinations with either the 10-Valent or the 13-Valent Vaccine.

van Westen E, Knol MJ, Wijmenga-Monsuur AJ, Tcherniaeva I, Schouls LM, Sanders EAM, van Els CACM, Berbers GAM, Rots NY.

Vaccines (Basel). 2018 Dec 11;6(4). pii: E82. doi: 10.3390/vaccines6040082.

7.

Detection of opsonizing antibodies directed against a recently circulating Bordetella pertussis strain in paired plasma samples from symptomatic and recovered pertussis patients.

Hovingh ES, Kuipers B, Bonačić Marinović AA, Jan Hamstra H, Hijdra D, Mughini Gras L, van Twillert I, Jongerius I, van Els CACM, Pinelli E.

Sci Rep. 2018 Aug 13;8(1):12039. doi: 10.1038/s41598-018-30558-8.

8.

Vaccine antigens modulate the innate response of monocytes to Al(OH)3.

Kooijman S, Brummelman J, van Els CACM, Marino F, Heck AJR, van Riet E, Metz B, Kersten GFA, Pennings JLA, Meiring HD.

PLoS One. 2018 May 29;13(5):e0197885. doi: 10.1371/journal.pone.0197885. eCollection 2018.

9.

Immunodominance in T cell responses elicited against different domains of detoxified pneumolysin PlyD1.

van Westen E, Poelen MCM, van den Dobbelsteen GPJM, Oloo EO, Ochs MM, Rots NY, van Els CACM.

PLoS One. 2018 Mar 6;13(3):e0193650. doi: 10.1371/journal.pone.0193650. eCollection 2018.

10.

Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination.

Raeven RHM, Brummelman J, Pennings JLA, van der Maas L, Helm K, Tilstra W, van der Ark A, Sloots A, van der Ley P, van Eden W, Jiskoot W, van Riet E, van Els CACM, Kersten GFA, Han WGH, Metz B.

Mucosal Immunol. 2018 May;11(3):1009. doi: 10.1038/mi.2017.110. Epub 2018 Feb 7.

PMID:
29411776
11.

Mumps infection but not childhood vaccination induces persistent polyfunctional CD8+ T-cell memory.

de Wit J, Emmelot ME, Poelen MCM, van Binnendijk RS, van der Lee S, van Baarle D, Han WGH, van Els CACM, Kaaijk P.

J Allergy Clin Immunol. 2018 May;141(5):1908-1911.e12. doi: 10.1016/j.jaci.2017.11.047. Epub 2018 Jan 12. No abstract available.

12.

Novel identified aluminum hydroxide-induced pathways prove monocyte activation and pro-inflammatory preparedness.

Kooijman S, Brummelman J, van Els CACM, Marino F, Heck AJR, Mommen GPM, Metz B, Kersten GFA, Pennings JLA, Meiring HD.

J Proteomics. 2018 Mar 20;175:144-155. doi: 10.1016/j.jprot.2017.12.021. Epub 2018 Jan 6.

13.

Diversity of aging of the immune system classified in the cotton rat (Sigmodon hispidus) model of human infectious diseases.

Guichelaar T, van Erp EA, Hoeboer J, Smits NAM, van Els CACM, Pieren DKJ, Luytjes W.

Dev Comp Immunol. 2018 May;82:39-48. doi: 10.1016/j.dci.2017.12.026. Epub 2018 Jan 2.

14.

The SysteMHC Atlas project.

Shao W, Pedrioli PGA, Wolski W, Scurtescu C, Schmid E, Vizcaíno JA, Courcelles M, Schuster H, Kowalewski D, Marino F, Arlehamn CSL, Vaughan K, Peters B, Sette A, Ottenhoff THM, Meijgaarden KE, Nieuwenhuizen N, Kaufmann SHE, Schlapbach R, Castle JC, Nesvizhskii AI, Nielsen M, Deutsch EW, Campbell DS, Moritz RL, Zubarev RA, Ytterberg AJ, Purcell AW, Marcilla M, Paradela A, Wang Q, Costello CE, Ternette N, van Veelen PA, van Els CACM, Heck AJR, de Souza GA, Sollid LM, Admon A, Stevanovic S, Rammensee HG, Thibault P, Perreault C, Bassani-Sternberg M, Aebersold R, Caron E.

Nucleic Acids Res. 2018 Jan 4;46(D1):D1237-D1247. doi: 10.1093/nar/gkx664.

15.

Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination.

Raeven RH, Brummelman J, Pennings JLA, van der Maas L, Helm K, Tilstra W, van der Ark A, Sloots A, van der Ley P, van Eden W, Jiskoot W, van Riet E, van Els CA, Kersten GF, Han WG, Metz B.

Mucosal Immunol. 2018 May;11(3):979-993. doi: 10.1038/mi.2017.81. Epub 2017 Sep 20. Erratum in: Mucosal Immunol. 2018 Feb 07;:.

PMID:
28930286
16.

Erratum for Carbonetti et al., "Highlights of the 11th International Bordetella Symposium: from Basic Biology to Vaccine Development".

Carbonetti NH, Wirsing von König CH, Lan R, Jacob-Dubuisson F, Cotter PA, Deora R, Merkel TJ, van Els CA, Locht C, Hozbor D, Rodriguez ME.

Clin Vaccine Immunol. 2017 May 5;24(5). pii: e00071-17. doi: 10.1128/CVI.00071-17. Print 2017 May. No abstract available.

17.

Impact of age and vaccination history on long-term serological responses after symptomatic B. pertussis infection, a high dimensional data analysis.

van Twillert I, Bonačić Marinović AA, Kuipers B, van Gaans-van den Brink JA, Sanders EA, van Els CA.

Sci Rep. 2017 Jan 16;7:40328. doi: 10.1038/srep40328.

18.

Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine.

Raeven RH, Brummelman J, Pennings JL, van der Maas L, Tilstra W, Helm K, van Riet E, Jiskoot W, van Els CA, Han WG, Kersten GF, Metz B.

Sci Rep. 2016 Dec 1;6:38240. doi: 10.1038/srep38240.

19.

Immunological Signatures after Bordetella pertussis Infection Demonstrate Importance of Pulmonary Innate Immune Cells.

Raeven RH, Brummelman J, van der Maas L, Tilstra W, Pennings JL, Han WG, van Els CA, van Riet E, Kersten GF, Metz B.

PLoS One. 2016 Oct 6;11(10):e0164027. doi: 10.1371/journal.pone.0164027. eCollection 2016.

20.

Highlights of the 11th International Bordetella Symposium: from Basic Biology to Vaccine Development.

Carbonetti NH, Wirsing von König CH, Lan R, Jacob-Dubuisson F, Cotter PA, Deora R, Merkel TJ, van Els CA, Locht C, Hozbor D, Rodriguez ME.

Clin Vaccine Immunol. 2016 Nov 4;23(11):842-850. Print 2016 Nov. Erratum in: Clin Vaccine Immunol. 2017 May 5;24(5):.

21.

Arginine (Di)methylated Human Leukocyte Antigen Class I Peptides Are Favorably Presented by HLA-B*07.

Marino F, Mommen GP, Jeko A, Meiring HD, van Gaans-van den Brink JA, Scheltema RA, van Els CA, Heck AJ.

J Proteome Res. 2017 Jan 6;16(1):34-44. doi: 10.1021/acs.jproteome.6b00528. Epub 2016 Aug 25.

PMID:
27503676
22.

Adaptive immune response to whole cell pertussis vaccine reflects vaccine quality: A possible complementation to the Pertussis Serological Potency test.

Hoonakker ME, Verhagen LM, van der Maas L, Metz B, Uittenbogaard JP, van de Waterbeemd B, van Els CA, van Eden W, Hendriksen CF, Sloots A, Han WG.

Vaccine. 2016 Aug 17;34(37):4429-36. doi: 10.1016/j.vaccine.2016.07.011. Epub 2016 Jul 21.

PMID:
27452867
23.

Mumps-specific cross-neutralization by MMR vaccine-induced antibodies predicts protection against mumps virus infection.

Gouma S, Ten Hulscher HI, Schurink-van 't Klooster TM, de Melker HE, Boland GJ, Kaaijk P, van Els CACM, Koopmans MPG, van Binnendijk RS.

Vaccine. 2016 Jul 29;34(35):4166-4171. doi: 10.1016/j.vaccine.2016.06.063. Epub 2016 Jun 29.

PMID:
27372154
24.

Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4(+) T cell responses through TLR4 ligation.

Brummelman J, Raeven RH, Helm K, Pennings JL, Metz B, van Eden W, van Els CA, Han WG.

Sci Rep. 2016 Apr 27;6:25064. doi: 10.1038/srep25064.

25.

Association of Vitamin D Receptor Polymorphism with Susceptibility to Symptomatic Pertussis.

Han WG, Hodemaekers HM, Nagarajah B, Poelen MM, Helm K, Janssen R, van Els CA.

PLoS One. 2016 Feb 19;11(2):e0149576. doi: 10.1371/journal.pone.0149576. eCollection 2016.

26.

Development of an IFNγ ELISPOT for the analysis of the human T cell response against mumps virus.

Han WG, Emmelot ME, Jaadar H, Ten Hulscher HI, van Els CA, Kaaijk P.

J Immunol Methods. 2016 Apr;431:52-9. doi: 10.1016/j.jim.2016.02.010. Epub 2016 Feb 9.

27.

The Use of Innovative Two-Component Cluster Analysis and Serodiagnostic Cut-Off Methods to Estimate Prevalence of Pertussis Reinfections.

van Twillert I, Bonačić Marinović AA, van Gaans-van den Brink JA, Kuipers B, Berbers GA, van der Maas NA, Verheij TJ, Versteegh FG, Teunis PF, van Els CA.

PLoS One. 2016 Feb 5;11(2):e0148507. doi: 10.1371/journal.pone.0148507. eCollection 2016.

28.

Sampling From the Proteome to the Human Leukocyte Antigen-DR (HLA-DR) Ligandome Proceeds Via High Specificity.

Mommen GP, Marino F, Meiring HD, Poelen MC, van Gaans-van den Brink JA, Mohammed S, Heck AJ, van Els CA.

Mol Cell Proteomics. 2016 Apr;15(4):1412-23. doi: 10.1074/mcp.M115.055780. Epub 2016 Jan 13.

29.

Measles Virus Epitope Presentation by HLA: Novel Insights into Epitope Selection, Dominance, and Microvariation.

Schellens IM, Meiring HD, Hoof I, Spijkers SN, Poelen MC, van Gaans-van den Brink JA, Costa AI, Vennema H, Keşmir C, van Baarle D, van Els CA.

Front Immunol. 2015 Nov 2;6:546. doi: 10.3389/fimmu.2015.00546. eCollection 2015.

30.

Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome.

Schellens IM, Hoof I, Meiring HD, Spijkers SN, Poelen MC, van Gaans-van den Brink JA, van der Poel K, Costa AI, van Els CA, van Baarle D, Kesmir C.

PLoS One. 2015 Sep 16;10(9):e0136417. doi: 10.1371/journal.pone.0136417. eCollection 2015.

31.

Waning and aging of cellular immunity to Bordetella pertussis.

van Twillert I, Han WG, van Els CA.

Pathog Dis. 2015 Nov;73(8):ftv071. doi: 10.1093/femspd/ftv071. Epub 2015 Sep 13. Review.

32.

Roads to the development of improved pertussis vaccines paved by immunology.

Brummelman J, Wilk MM, Han WG, van Els CA, Mills KH.

Pathog Dis. 2015 Nov;73(8):ftv067. doi: 10.1093/femspd/ftv067. Epub 2015 Sep 6. Review.

33.

Extended O-GlcNAc on HLA Class-I-Bound Peptides.

Marino F, Bern M, Mommen GPM, Leney AC, van Gaans-van den Brink JAM, Bonvin AMJJ, Becker C, van Els CACM, Heck AJR.

J Am Chem Soc. 2015 Sep 2;137(34):10922-10925. doi: 10.1021/jacs.5b06586. Epub 2015 Aug 19.

34.

Dynamics of the serologic response in vaccinated and unvaccinated mumps cases during an epidemic.

Kaaijk P, Gouma S, Hulscher HI, Han WG, Kleijne DE, van Binnendijk RS, van Els CA.

Hum Vaccin Immunother. 2015;11(7):1754-61. doi: 10.1080/21645515.2015.1040967.

35.

Differential B-cell memory around the 11-month booster in children vaccinated with a 10- or 13-valent pneumococcal conjugate vaccine.

van Westen E, Wijmenga-Monsuur AJ, van Dijken HH, van Gaans-van den Brink JA, Kuipers B, Knol MJ, Berbers GA, Sanders EA, Rots NY, van Els CA.

Clin Infect Dis. 2015 Aug 1;61(3):342-9. doi: 10.1093/cid/civ274. Epub 2015 Apr 1.

36.

Identification of pertussis-specific effector memory T cells in preschool children.

de Rond L, Schure RM, Öztürk K, Berbers G, Sanders E, van Twillert I, Carollo M, Mascart F, Ausiello CM, van Els CA, Smits K, Buisman AM.

Clin Vaccine Immunol. 2015 May;22(5):561-9. doi: 10.1128/CVI.00695-14. Epub 2015 Mar 18.

37.

Mumps serum antibody levels before and after an outbreak to assess infection and immunity in vaccinated students.

Gouma S, Schurink-Van't Klooster TM, de Melker HE, Kerkhof J, Smits GP, Hahné SJ, van Els CA, Boland GJ, Vossen AC, Goswami PR, Koopmans MP, van Binnendijk RS.

Open Forum Infect Dis. 2014 Nov 13;1(3):ofu101. doi: 10.1093/ofid/ofu101. eCollection 2014 Dec.

38.

Ex vivo peptide-MHC II tetramer analysis reveals distinct end-differentiation patterns of human pertussis-specific CD4(+) T cells following clinical infection.

Han WG, Helm K, Poelen MM, Otten HG, van Els CA.

Clin Immunol. 2015 Apr;157(2):205-15. doi: 10.1016/j.clim.2015.02.009. Epub 2015 Feb 27.

PMID:
25728491
39.

Modulation of the CD4(+) T cell response after acellular pertussis vaccination in the presence of TLR4 ligation.

Brummelman J, Helm K, Hamstra HJ, van der Ley P, Boog CJ, Han WG, van Els CA.

Vaccine. 2015 Mar 17;33(12):1483-91. doi: 10.1016/j.vaccine.2015.01.063. Epub 2015 Feb 7.

PMID:
25659267
40.

In vitro innate immune cell based models to assess whole cell Bordetella pertussis vaccine quality: a proof of principle.

Hoonakker ME, Verhagen LM, Hendriksen CF, van Els CA, Vandebriel RJ, Sloots A, Han WG.

Biologicals. 2015 Mar;43(2):100-9. doi: 10.1016/j.biologicals.2014.12.002. Epub 2015 Jan 26.

PMID:
25633359
41.

Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells.

Brummelman J, Veerman RE, Hamstra HJ, Deuss AJ, Schuijt TJ, Sloots A, Kuipers B, van Els CA, van der Ley P, Mooi FR, Han WG, Pinelli E.

Infect Immun. 2015 Jan;83(1):227-38. doi: 10.1128/IAI.02197-14. Epub 2014 Oct 27.

42.

Toward Understanding the Essence of Post-Translational Modifications for the Mycobacterium tuberculosis Immunoproteome.

van Els CA, Corbière V, Smits K, van Gaans-van den Brink JA, Poelen MC, Mascart F, Meiring HD, Locht C.

Front Immunol. 2014 Aug 11;5:361. doi: 10.3389/fimmu.2014.00361. eCollection 2014. Review.

43.

Molecular signatures of the evolving immune response in mice following a Bordetella pertussis infection.

Raeven RH, Brummelman J, Pennings JL, Nijst OE, Kuipers B, Blok LE, Helm K, van Riet E, Jiskoot W, van Els CA, Han WG, Kersten GF, Metz B.

PLoS One. 2014 Aug 19;9(8):e104548. doi: 10.1371/journal.pone.0104548. eCollection 2014.

44.

Impaired immune response to vaccination against infection with human respiratory syncytial virus at advanced age.

Guichelaar T, Hoeboer J, Widjojoatmodjo MN, Reemers SS, van Els CA, Otten R, van Remmerden Y, Boes J, Luytjes W.

J Virol. 2014 Sep 1;88(17):9744-50. doi: 10.1128/JVI.01101-14. Epub 2014 Jun 11.

45.

Expanding the detectable HLA peptide repertoire using electron-transfer/higher-energy collision dissociation (EThcD).

Mommen GP, Frese CK, Meiring HD, van Gaans-van den Brink J, de Jong AP, van Els CA, Heck AJ.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4507-12. doi: 10.1073/pnas.1321458111. Epub 2014 Mar 10.

46.

Bordetella pertussis proteins dominating the major histocompatibility complex class II-presented epitope repertoire in human monocyte-derived dendritic cells.

Stenger RM, Meiring HD, Kuipers B, Poelen M, van Gaans-van den Brink JA, Boog CJ, de Jong AP, van Els CA.

Clin Vaccine Immunol. 2014 May;21(5):641-50. doi: 10.1128/CVI.00665-13. Epub 2014 Mar 5.

47.

Age related differences in dynamics of specific memory B cell populations after clinical pertussis infection.

van Twillert I, van Gaans-van den Brink JA, Poelen MC, Helm K, Kuipers B, Schipper M, Boog CJ, Verheij TJ, Versteegh FG, van Els CA.

PLoS One. 2014 Jan 13;9(1):e85227. doi: 10.1371/journal.pone.0085227. eCollection 2014.

48.

Loss of multi-epitope specificity in memory CD4(+) T cell responses to B. pertussis with age.

Han WG, van Twillert I, Poelen MC, Helm K, van de Kassteele J, Verheij TJ, Versteegh FG, Boog CJ, van Els CA.

PLoS One. 2013 Dec 31;8(12):e83583. doi: 10.1371/journal.pone.0083583. eCollection 2013.

49.

Resurgence of pertussis calls for re-evaluation of pertussis animal models.

van der Ark AA, Hozbor DF, Boog CJ, Metz B, van den Dobbelsteen GP, van Els CA.

Expert Rev Vaccines. 2012 Sep;11(9):1121-37. doi: 10.1586/erv.12.83. Review.

PMID:
23151168
50.

Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis.

van Herwijnen MJ, Wieten L, van der Zee R, van Kooten PJ, Wagenaar-Hilbers JP, Hoek A, den Braber I, Anderton SM, Singh M, Meiring HD, van Els CA, van Eden W, Broere F.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14134-9. doi: 10.1073/pnas.1206803109. Epub 2012 Aug 13.

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