Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 83


TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells.

Arhatte M, Gunaratne GS, El Boustany C, Kuo IY, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-Gervais S, Ehrlich BE, Marchant JS, Savage AM, van Eeden FJM, Wilkinson RN, Demolombe S, Honoré E, Patel A.

Nat Commun. 2019 May 2;10(1):2024. doi: 10.1038/s41467-019-10045-y.


tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis.

Savage AM, Kurusamy S, Chen Y, Jiang Z, Chhabria K, MacDonald RB, Kim HR, Wilson HL, van Eeden FJM, Armesilla AL, Chico TJA, Wilkinson RN.

Nat Commun. 2019 Feb 13;10(1):732. doi: 10.1038/s41467-019-08590-7.


The Zebrafish as an Emerging Model to Study DNA Damage in Aging, Cancer and Other Diseases.

Cayuela ML, Claes KBM, Ferreira MG, Henriques CM, van Eeden F, Varga M, Vierstraete J, Mione MC.

Front Cell Dev Biol. 2019 Jan 10;6:178. doi: 10.3389/fcell.2018.00178. eCollection 2018.


A resistance exercise set for a total body workout for adults with intellectual disabilities, a pilot study.

Weterings S, Oppewal A, van Eeden FMM, Hilgenkamp TIM.

J Appl Res Intellect Disabil. 2019 May;32(3):730-736. doi: 10.1111/jar.12552. Epub 2018 Dec 10.


The von Hippel-Lindau Gene Is Required to Maintain Renal Proximal Tubule and Glomerulus Integrity in Zebrafish Larvae.

van Rooijen E, van de Hoek G, Logister I, Ajzenberg H, Knoers NVAM, van Eeden F, Voest EE, Schulte-Merker S, Giles RH.

Nephron. 2018;138(4):310-323. doi: 10.1159/000484096. Epub 2018 Jan 17.


Nitric oxide interacts with monoamine oxidase to modulate aggression and anxiety-like behaviour.

Carreño Gutiérrez H, O'Leary A, Freudenberg F, Fedele G, Wilkinson R, Markham E, van Eeden F, Reif A, Norton WHJ.

Eur Neuropsychopharmacol. 2017 Sep 23. pii: S0924-977X(17)30906-9. doi: 10.1016/j.euroneuro.2017.09.004. [Epub ahead of print]


Glucocorticoids promote Von Hippel Lindau degradation and Hif-1α stabilization.

Vettori A, Greenald D, Wilson GK, Peron M, Facchinello N, Markham E, Sinnakaruppan M, Matthews LC, McKeating JA, Argenton F, van Eeden FJM.

Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9948-9953. doi: 10.1073/pnas.1705338114. Epub 2017 Aug 29.


The Power of Zebrafish in Personalised Medicine.

Baxendale S, van Eeden F, Wilkinson R.

Adv Exp Med Biol. 2017;1007:179-197. doi: 10.1007/978-3-319-60733-7_10. Review.


Zebrafish as a model for von Hippel Lindau and hypoxia-inducible factor signaling.

Kim HR, Greenald D, Vettori A, Markham E, Santhakumar K, Argenton F, van Eeden F.

Methods Cell Biol. 2017;138:497-523. doi: 10.1016/bs.mcb.2016.07.001. Epub 2016 Sep 6. Review.


Hedgehog signalling acts upstream of Laminin alpha1 transcription in the zebrafish paraxial mesoderm.

Pickering J, Cunliffe VT, Van Eeden F, Borycki AG.

Matrix Biol. 2017 Oct;62:58-74. doi: 10.1016/j.matbio.2016.11.004. Epub 2016 Nov 14.


Euthanizing zebrafish legally in Europe: Are the approved methods of euthanizing zebrafish appropriate to research reality and animal welfare?

Valentim AM, van Eeden FJ, Strähle U, Olsson IA.

EMBO Rep. 2016 Dec;17(12):1688-1689. Epub 2016 Oct 18. No abstract available.


Efficacy and Safety of Leg-Press Training With Moderate Vibration After Total Knee Arthroplasty Remains Unclear.

van Eeden FM, van Halewijn KF, Swart NM, Festen DA.

Arch Phys Med Rehabil. 2016 Nov;97(11):2018. doi: 10.1016/j.apmr.2016.06.025. No abstract available.


Genome-wide mapping of Hif-1α binding sites in zebrafish.

Greenald D, Jeyakani J, Pelster B, Sealy I, Mathavan S, van Eeden FJ.

BMC Genomics. 2015 Nov 11;16:923. doi: 10.1186/s12864-015-2169-x.


Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models.

Elks PM, Renshaw SA, Meijer AH, Walmsley SR, van Eeden FJ.

Dis Model Mech. 2015 Nov;8(11):1349-60. doi: 10.1242/dmm.021865. Review.


klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes.

Novodvorsky P, Watson O, Gray C, Wilkinson RN, Reeve S, Smythe C, Beniston R, Plant K, Maguire R, M K Rothman A, Elworthy S, van Eeden FJ, Chico TJ.

PLoS One. 2015 Oct 27;10(10):e0141611. doi: 10.1371/journal.pone.0141611. eCollection 2015.


The zebrafish as a model of vascular development and disease.

Wilkinson RN, van Eeden FJ.

Prog Mol Biol Transl Sci. 2014;124:93-122. doi: 10.1016/B978-0-12-386930-2.00005-7. Review.


Zebrafish as a model of cardiac disease.

Wilkinson RN, Jopling C, van Eeden FJ.

Prog Mol Biol Transl Sci. 2014;124:65-91. doi: 10.1016/B978-0-12-386930-2.00004-5. Review.


Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism.

Elks PM, Brizee S, van der Vaart M, Walmsley SR, van Eeden FJ, Renshaw SA, Meijer AH.

PLoS Pathog. 2013;9(12):e1003789. doi: 10.1371/journal.ppat.1003789. Epub 2013 Dec 19.


A method for high-throughput PCR-based genotyping of larval zebrafish tail biopsies.

Wilkinson RN, Elworthy S, Ingham PW, van Eeden FJ.

Biotechniques. 2013 Dec;55(6):314-6. doi: 10.2144/000114116.


Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

Maurya AK, Ben J, Zhao Z, Lee RT, Niah W, Ng AS, Iyu A, Yu W, Elworthy S, van Eeden FJ, Ingham PW.

PLoS Genet. 2013;9(12):e1003955. doi: 10.1371/journal.pgen.1003955. Epub 2013 Dec 5.


Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish.

Thompson AA, Elks PM, Marriott HM, Eamsamarng S, Higgins KR, Lewis A, Williams L, Parmar S, Shaw G, McGrath EE, Formenti F, Van Eeden FJ, Kinnula VL, Pugh CW, Sabroe I, Dockrell DH, Chilvers ER, Robbins PA, Percy MJ, Simon MC, Johnson RS, Renshaw SA, Whyte MK, Walmsley SR.

Blood. 2014 Jan 16;123(3):366-76. doi: 10.1182/blood-2013-05-500207. Epub 2013 Nov 6.


Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling.

Watson O, Novodvorsky P, Gray C, Rothman AM, Lawrie A, Crossman DC, Haase A, McMahon K, Gering M, Van Eeden FJ, Chico TJ.

Cardiovasc Res. 2013 Nov 1;100(2):252-61. doi: 10.1093/cvr/cvt170. Epub 2013 Jul 30.


Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases.

Chowdhury R, Candela-Lena JI, Chan MC, Greenald DJ, Yeoh KK, Tian YM, McDonough MA, Tumber A, Rose NR, Conejo-Garcia A, Demetriades M, Mathavan S, Kawamura A, Lee MK, van Eeden F, Pugh CW, Ratcliffe PJ, Schofield CJ.

ACS Chem Biol. 2013 Jul 19;8(7):1488-96. doi: 10.1021/cb400088q. Epub 2013 Jun 12.


Mutations in LRRC50 predispose zebrafish and humans to seminomas.

Basten SG, Davis EE, Gillis AJ, van Rooijen E, Stoop H, Babala N, Logister I, Heath ZG, Jonges TN, Katsanis N, Voest EE, van Eeden FJ, Medema RH, Ketting RF, Schulte-Merker S, Looijenga LH, Giles RH.

PLoS Genet. 2013 Apr;9(4):e1003384. doi: 10.1371/journal.pgen.1003384. Epub 2013 Apr 11.


A systematic genome-wide analysis of zebrafish protein-coding gene function.

Kettleborough RN, Busch-Nentwich EM, Harvey SA, Dooley CM, de Bruijn E, van Eeden F, Sealy I, White RJ, Herd C, Nijman IJ, Fényes F, Mehroke S, Scahill C, Gibbons R, Wali N, Carruthers S, Hall A, Yen J, Cuppen E, Stemple DL.

Nature. 2013 Apr 25;496(7446):494-7. doi: 10.1038/nature11992. Epub 2013 Apr 17.


Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish.

Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ.

Blood. 2012 Jul 12;120(2):477-88. doi: 10.1182/blood-2011-10-383729. Epub 2012 Jun 5.


A zebrafish model to study and therapeutically manipulate hypoxia signaling in tumorigenesis.

Santhakumar K, Judson EC, Elks PM, McKee S, Elworthy S, van Rooijen E, Walmsley SS, Renshaw SA, Cross SS, van Eeden FJ.

Cancer Res. 2012 Aug 15;72(16):4017-27. doi: 10.1158/0008-5472.CAN-11-3148. Epub 2012 Jun 4.


Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants.

Sapetto-Rebow B, McLoughlin SC, O'Shea LC, O'Leary O, Willer JR, Alvarez Y, Collery R, O'Sullivan J, Van Eeden F, Hensey C, Kennedy BN.

BMC Dev Biol. 2011 Nov 23;11:71. doi: 10.1186/1471-213X-11-71.


Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates.

Ben J, Elworthy S, Ng AS, van Eeden F, Ingham PW.

Development. 2011 Nov;138(22):4969-78. doi: 10.1242/dev.070862.


A zebrafish model for VHL and hypoxia signaling.

van Rooijen E, Santhakumar K, Logister I, Voest E, Schulte-Merker S, Giles R, van Eeden F.

Methods Cell Biol. 2011;105:163-90. doi: 10.1016/B978-0-12-381320-6.00007-2.


Activation of hypoxia-inducible factor-1α (Hif-1α) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model.

Elks PM, van Eeden FJ, Dixon G, Wang X, Reyes-Aldasoro CC, Ingham PW, Whyte MK, Walmsley SR, Renshaw SA.

Blood. 2011 Jul 21;118(3):712-22. doi: 10.1182/blood-2010-12-324186. Epub 2011 May 9.


von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish.

van Rooijen E, Voest EE, Logister I, Bussmann J, Korving J, van Eeden FJ, Giles RH, Schulte-Merker S.

Dis Model Mech. 2010 May-Jun;3(5-6):343-53. doi: 10.1242/dmm.004036. Epub 2010 Mar 24.


Repression of Hedgehog signalling is required for the acquisition of dorsolateral cell fates in the zebrafish otic vesicle.

Hammond KL, van Eeden FJ, Whitfield TT.

Development. 2010 Apr;137(8):1361-71. doi: 10.1242/dev.045666. Epub 2010 Mar 10.


Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia.

van Rooijen E, Voest EE, Logister I, Korving J, Schwerte T, Schulte-Merker S, Giles RH, van Eeden FJ.

Blood. 2009 Jun 18;113(25):6449-60. doi: 10.1182/blood-2008-07-167890. Epub 2009 Mar 20.


Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential.

Thomas NA, Koudijs M, van Eeden FJ, Joyner AL, Yelon D.

Development. 2008 Nov;135(22):3789-99. doi: 10.1242/dev.024083. Epub 2008 Oct 8.


LRRC50, a conserved ciliary protein implicated in polycystic kidney disease.

van Rooijen E, Giles RH, Voest EE, van Rooijen C, Schulte-Merker S, van Eeden FJ.

J Am Soc Nephrol. 2008 Jun;19(6):1128-38. doi: 10.1681/ASN.2007080917. Epub 2008 Apr 2.


Genetic analysis of the two zebrafish patched homologues identifies novel roles for the hedgehog signaling pathway.

Koudijs MJ, den Broeder MJ, Groot E, van Eeden FJ.

BMC Dev Biol. 2008 Feb 19;8:15. doi: 10.1186/1471-213X-8-15.


Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells.

Knöll R, Postel R, Wang J, Krätzner R, Hennecke G, Vacaru AM, Vakeel P, Schubert C, Murthy K, Rana BK, Kube D, Knöll G, Schäfer K, Hayashi T, Holm T, Kimura A, Schork N, Toliat MR, Nürnberg P, Schultheiss HP, Schaper W, Schaper J, Bos E, Den Hertog J, van Eeden FJ, Peters PJ, Hasenfuss G, Chien KR, Bakkers J.

Circulation. 2007 Jul 31;116(5):515-25. Epub 2007 Jul 23.


Genetic variation in the zebrafish.

Guryev V, Koudijs MJ, Berezikov E, Johnson SL, Plasterk RH, van Eeden FJ, Cuppen E.

Genome Res. 2006 Apr;16(4):491-7. Epub 2006 Mar 13.


The zebrafish mutants dre, uki, and lep encode negative regulators of the hedgehog signaling pathway.

Koudijs MJ, den Broeder MJ, Keijser A, Wienholds E, Houwing S, van Rooijen EM, Geisler R, van Eeden FJ.

PLoS Genet. 2005 Aug;1(2):e19. Epub 2005 Aug 19.


Zebrafish rx3 and mab21l2 are required during eye morphogenesis.

Kennedy BN, Stearns GW, Smyth VA, Ramamurthy V, van Eeden F, Ankoudinova I, Raible D, Hurley JB, Brockerhoff SE.

Dev Biol. 2004 Jun 15;270(2):336-49.


Efficient target-selected mutagenesis in zebrafish.

Wienholds E, van Eeden F, Kosters M, Mudde J, Plasterk RH, Cuppen E.

Genome Res. 2003 Dec;13(12):2700-7. Epub 2003 Nov 12.


The Wnt/beta-catenin pathway regulates cardiac valve formation.

Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H.

Nature. 2003 Oct 9;425(6958):633-7.


The microRNA-producing enzyme Dicer1 is essential for zebrafish development.

Wienholds E, Koudijs MJ, van Eeden FJ, Cuppen E, Plasterk RH.

Nat Genet. 2003 Nov;35(3):217-8. Epub 2003 Oct 5.


Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections.

van der Sar AM, Musters RJ, van Eeden FJ, Appelmelk BJ, Vandenbroucke-Grauls CM, Bitter W.

Cell Microbiol. 2003 Sep;5(9):601-11.


Barentsz is essential for the posterior localization of oskar mRNA and colocalizes with it to the posterior pole.

van Eeden FJ, Palacios IM, Petronczki M, Weston MJ, St Johnston D.

J Cell Biol. 2001 Aug 6;154(3):511-23. Epub 2001 Jul 30.


Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways.

Odenthal J, van Eeden FJ, Haffter P, Ingham PW, Nüsslein-Volhard C.

Dev Biol. 2000 Mar 15;219(2):350-63.


The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis.

van Eeden F, St Johnston D.

Curr Opin Genet Dev. 1999 Aug;9(4):396-404. Review.


Developmental mutant screens in the zebrafish.

van Eeden FJ, Granato M, Odenthal J, Haffter P.

Methods Cell Biol. 1999;60:21-41. Review. No abstract available.


Supplemental Content

Loading ...
Support Center