Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 267


Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis.

Spiering R, Jansen MAA, Wood MJ, Fath AA, Eltherington O, Anderson AE, Pratt AG, van Eden W, Isaacs JD, Broere F, Hilkens CMU.

J Transl Med. 2019 Nov 14;17(1):375. doi: 10.1186/s12967-019-2128-4.


Matured Tolerogenic Dendritic Cells Effectively Inhibit Autoantigen Specific CD4+ T Cells in a Murine Arthritis Model.

Jansen MAA, Spiering R, Ludwig IS, van Eden W, Hilkens CMU, Broere F.

Front Immunol. 2019 Aug 28;10:2068. doi: 10.3389/fimmu.2019.02068. eCollection 2019.


Lipidoid-polymer hybrid nanoparticles loaded with TNF siRNA suppress inflammation after intra-articular administration in a murine experimental arthritis model.

Jansen MAA, Klausen LH, Thanki K, Lyngsø J, Skov Pedersen J, Franzyk H, Nielsen HM, van Eden W, Dong M, Broere F, Foged C, Zeng X.

Eur J Pharm Biopharm. 2019 Sep;142:38-48. doi: 10.1016/j.ejpb.2019.06.009. Epub 2019 Jun 11.


Factors influencing long-term survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei originating from appendiceal neoplasms.

van Eden WJ, Kok NFM, Snaebjornsson P, Jóźwiak K, Woensdregt K, Bottenberg PD, Boot H, Aalbers AGJ.

BJS Open. 2019 Feb 19;3(3):376-386. doi: 10.1002/bjs5.50134. eCollection 2019 Jun.


Vaccination against autoimmune diseases moves closer to the clinic.

van Eden W.

Hum Vaccin Immunother. 2019 Mar 22:1-5. doi: 10.1080/21645515.2019.1593085. [Epub ahead of print]


Heat Shock Proteins Can Be Surrogate Autoantigens for Induction of Antigen Specific Therapeutic Tolerance in Rheumatoid Arthritis.

van Eden W, Jansen MAA, Ludwig IS, Leufkens P, van der Goes MC, van Laar JM, Broere F.

Front Immunol. 2019 Feb 22;10:279. doi: 10.3389/fimmu.2019.00279. eCollection 2019. Review.


Editorial: Stress and Immunity.

Bae YS, Shin EC, Bae YS, Van Eden W.

Front Immunol. 2019 Feb 14;10:245. doi: 10.3389/fimmu.2019.00245. eCollection 2019. No abstract available.


Diffusion-weighted MRI assessment of the peritoneal cancer index before cytoreductive surgery.

van 't Sant I, van Eden WJ, Engbersen MP, Kok NFM, Woensdregt K, Lambregts DMJ, Shanmuganathan S, Beets-Tan RGH, Aalbers AGJ, Lahaye MJ.

Br J Surg. 2019 Mar;106(4):491-498. doi: 10.1002/bjs.10989. Epub 2018 Oct 24.


The Well-Developed Mucosal Immune Systems of Birds and Mammals Allow for Similar Approaches of Mucosal Vaccination in Both Types of Animals.

Nochi T, Jansen CA, Toyomizu M, van Eden W.

Front Nutr. 2018 Jul 12;5:60. doi: 10.3389/fnut.2018.00060. eCollection 2018. Review.


Lactobacillus rhamnosus GG-Derived Soluble Mediators Modulate Adaptive Immune Cells.

Ludwig IS, Broere F, Manurung S, Lambers TT, van der Zee R, van Eden W.

Front Immunol. 2018 Jul 10;9:1546. doi: 10.3389/fimmu.2018.01546. eCollection 2018.


Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design.

de Groot AM, Thanki K, Gangloff M, Falkenberg E, Zeng X, van Bijnen DCJ, van Eden W, Franzyk H, Nielsen HM, Broere F, Gay NJ, Foged C, Sijts AJAM.

Mol Ther Nucleic Acids. 2018 Jun 1;11:159-169. doi: 10.1016/j.omtn.2018.02.003. Epub 2018 Feb 13.


Treatment of Isolated Peritoneal Recurrences in Patients with Colorectal Peritoneal Metastases Previously Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.

van Eden WJ, Elekonawo FMK, Starremans BJ, Kok NFM, Bremers AJA, de Wilt JHW, Aalbers AGJ.

Ann Surg Oncol. 2018 Jul;25(7):1992-2001. doi: 10.1245/s10434-018-6423-8. Epub 2018 Apr 18.


Immunobiotics for the Bovine Host: Their Interaction with Intestinal Epithelial Cells and Their Effect on Antiviral Immunity.

Villena J, Aso H, Rutten VPMG, Takahashi H, van Eden W, Kitazawa H.

Front Immunol. 2018 Mar 2;9:326. doi: 10.3389/fimmu.2018.00326. eCollection 2018. Review.


Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination.

Raeven RHM, Brummelman J, Pennings JLA, van der Maas L, Helm K, Tilstra W, van der Ark A, Sloots A, van der Ley P, van Eden W, Jiskoot W, van Riet E, van Els CACM, Kersten GFA, Han WGH, Metz B.

Mucosal Immunol. 2018 May;11(3):1009. doi: 10.1038/mi.2017.110. Epub 2018 Feb 7.


Routing dependent immune responses after experimental R848-adjuvated vaccination.

van Aalst S, Jansen MAA, Ludwig IS, van der Zee R, van Eden W, Broere F.

Vaccine. 2018 Mar 7;36(11):1405-1413. doi: 10.1016/j.vaccine.2018.01.077.


Histopathological and molecular classification of colorectal cancer and corresponding peritoneal metastases.

Ubink I, van Eden WJ, Snaebjornsson P, Kok NFM, van Kuik J, van Grevenstein WMU, Laclé MM, Sanders J, Fijneman RJA, Elias SG, Borel Rinkes IHM, Aalbers AGJ, Kranenburg O.

Br J Surg. 2018 Jan;105(2):e204-e211. doi: 10.1002/bjs.10788.


Safety of intraperitoneal Mitomycin C versus intraperitoneal oxaliplatin in patients with peritoneal carcinomatosis of colorectal cancer undergoing cytoreductive surgery and HIPEC.

van Eden WJ, Kok NFM, Woensdregt K, Huitema ADR, Boot H, Aalbers AGJ.

Eur J Surg Oncol. 2018 Feb;44(2):220-227. doi: 10.1016/j.ejso.2017.10.216. Epub 2017 Nov 15.


The Immunomodulatory Potential of tolDCs Loaded with Heat Shock Proteins.

van Eden W, Jansen MAA, de Wolf ACM, Ludwig IS, Leufkens P, Broere F.

Front Immunol. 2017 Nov 30;8:1690. doi: 10.3389/fimmu.2017.01690. eCollection 2017. Review.


The Enigma of Heat Shock Proteins in Immune Tolerance.

van Eden W, Jansen MAA, Ludwig I, van Kooten P, van der Zee R, Broere F.

Front Immunol. 2017 Nov 21;8:1599. doi: 10.3389/fimmu.2017.01599. eCollection 2017. Review.


Immune tolerance therapies for autoimmune diseases based on heat shock protein T-cell epitopes.

van Eden W.

Philos Trans R Soc Lond B Biol Sci. 2018 Jan 19;373(1738). pii: 20160531. doi: 10.1098/rstb.2016.0531. Review.


An Unexpected Major Role for Proteasome-Catalyzed Peptide Splicing in Generation of T Cell Epitopes: Is There Relevance for Vaccine Development?

Platteel ACM, Liepe J, van Eden W, Mishto M, Sijts AJAM.

Front Immunol. 2017 Nov 3;8:1441. doi: 10.3389/fimmu.2017.01441. eCollection 2017. Review.


T Cell-Mediated Chronic Inflammatory Diseases Are Candidates for Therapeutic Tolerance Induction with Heat Shock Proteins.

Barbera Betancourt A, Lyu Q, Broere F, Sijts A, Rutten VPMG, van Eden W.

Front Immunol. 2017 Oct 26;8:1408. doi: 10.3389/fimmu.2017.01408. eCollection 2017. Review.


Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination.

Raeven RH, Brummelman J, Pennings JLA, van der Maas L, Helm K, Tilstra W, van der Ark A, Sloots A, van der Ley P, van Eden W, Jiskoot W, van Riet E, van Els CA, Kersten GF, Han WG, Metz B.

Mucosal Immunol. 2018 May;11(3):979-993. doi: 10.1038/mi.2017.81. Epub 2017 Sep 20. Erratum in: Mucosal Immunol. 2018 Feb 07;:.


Targeting of tolerogenic dendritic cells towards heat-shock proteins: a novel therapeutic strategy for autoimmune diseases?

Jansen MAA, Spiering R, Broere F, van Laar JM, Isaacs JD, van Eden W, Hilkens CMU.

Immunology. 2018 Jan;153(1):51-59. doi: 10.1111/imm.12811. Epub 2017 Sep 18. Review.


Regulatory T cell frequencies and phenotypes following anti-viral vaccination.

de Wolf ACMT, van Aalst S, Ludwig IS, Bodinham CL, Lewis DJ, van der Zee R, van Eden W, Broere F.

PLoS One. 2017 Jun 28;12(6):e0179942. doi: 10.1371/journal.pone.0179942. eCollection 2017.


Bystander activation of irrelevant CD4+ T cells following antigen-specific vaccination occurs in the presence and absence of adjuvant.

van Aalst S, Ludwig IS, van der Zee R, van Eden W, Broere F.

PLoS One. 2017 May 10;12(5):e0177365. doi: 10.1371/journal.pone.0177365. eCollection 2017.


Timing of Systemic Chemotherapy in Patients With Colorectal Peritoneal Carcinomatosis Treated With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.

van Eden WJ, Kok NF, Jóźwiak K, Lahaye ML, Beets GL, van Leerdam ME, Boot H, Aalbers AG.

Dis Colon Rectum. 2017 May;60(5):477-487. doi: 10.1097/DCR.0000000000000774.


Dynamics of APC recruitment at the site of injection following injection of vaccine adjuvants.

van Aalst S, Ludwig IS, van Kooten PJS, van der Zee R, van Eden W, Broere F.

Vaccine. 2017 Mar 14;35(12):1622-1629. doi: 10.1016/j.vaccine.2017.02.005. Epub 2017 Feb 17.


Adaptive immune response to whole cell pertussis vaccine reflects vaccine quality: A possible complementation to the Pertussis Serological Potency test.

Hoonakker ME, Verhagen LM, van der Maas L, Metz B, Uittenbogaard JP, van de Waterbeemd B, van Els CA, van Eden W, Hendriksen CF, Sloots A, Han WG.

Vaccine. 2016 Aug 17;34(37):4429-36. doi: 10.1016/j.vaccine.2016.07.011. Epub 2016 Jul 21.


Heat shock proteins and their immunomodulatory role in inflammatory arthritis.

Spierings J, van Eden W.

Rheumatology (Oxford). 2017 Feb;56(2):198-208. doi: 10.1093/rheumatology/kew266. Epub 2016 Jul 13. Review.


[Impaired immunity: risk groups and consequences for general practice].

Opstelten W, Bijlsma JW, Gelinck LB, Hielkema CM, Verheij TJ, van Eden W.

Ned Tijdschr Geneeskd. 2016;160:A9752. Review. Dutch.


APL1, an altered peptide ligand derived from human heat-shock protein 60, increases the frequency of Tregs and its suppressive capacity against antigen responding effector CD4 + T cells from rheumatoid arthritis patients.

Barberá A, Lorenzo N, van Kooten P, van Roon J, de Jager W, Prada D, Gómez J, Padrón G, van Eden W, Broere F, Del Carmen Domínguez M.

Cell Stress Chaperones. 2016 Jul;21(4):735-44. doi: 10.1007/s12192-016-0698-0. Epub 2016 May 30.


Reduced TCR-dependent activation through citrullination of a T-cell epitope enhances Th17 development by disruption of the STAT3/5 balance.

Tibbitt C, Falconer J, Stoop J, van Eden W, Robinson JH, Hilkens CM.

Eur J Immunol. 2016 Jul;46(7):1633-43. doi: 10.1002/eji.201546217.


Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4(+) T cell responses through TLR4 ligation.

Brummelman J, Raeven RH, Helm K, Pennings JL, Metz B, van Eden W, van Els CA, Han WG.

Sci Rep. 2016 Apr 27;6:25064. doi: 10.1038/srep25064.


Generation of the First TCR Transgenic Mouse with CD4(+) T Cells Recognizing an Anti-inflammatory Regulatory T Cell-Inducing Hsp70 Peptide.

Jansen MA, van Herwijnen MJ, van Kooten PJ, Hoek A, van der Zee R, van Eden W, Broere F.

Front Immunol. 2016 Mar 9;7:90. doi: 10.3389/fimmu.2016.00090. eCollection 2016.


Surface coating of siRNA-peptidomimetic nano-self-assemblies with anionic lipid bilayers: enhanced gene silencing and reduced adverse effects in vitro.

Zeng X, de Groot AM, Sijts AJ, Broere F, Oude Blenke E, Colombo S, van Eden W, Franzyk H, Nielsen HM, Foged C.

Nanoscale. 2015 Dec 14;7(46):19687-98. doi: 10.1039/c5nr04807a.


Goals in Nutrition Science 2015-2020.

Allison DB, Bassaganya-Riera J, Burlingame B, Brown AW, le Coutre J, Dickson SL, van Eden W, Garssen J, Hontecillas R, Khoo CS, Knorr D, Kussmann M, Magistretti PJ, Mehta T, Meule A, Rychlik M, Vögele C.

Front Nutr. 2015 Sep 8;2:26. doi: 10.3389/fnut.2015.00026. eCollection 2015. No abstract available.


An Arthritis-Suppressive and Treg Cell-Inducing CD4+ T Cell Epitope Is Functional in the Context of HLA-Restricted T Cell Responses.

de Wolf C, van der Zee R, den Braber I, Glant T, Maillère B, Favry E, van Lummel M, Koning F, Hoek A, Ludwig I, van Eden W, Broere F.

Arthritis Rheumatol. 2016 Mar;68(3):639-47. doi: 10.1002/art.39444.


In Vivo Induction of Functionally Suppressive Induced Regulatory T Cells from CD4+CD25- T Cells Using an Hsp70 Peptide.

van Herwijnen MJ, van der Zee R, van Eden W, Broere F.

PLoS One. 2015 Jun 24;10(6):e0128373. doi: 10.1371/journal.pone.0128373. eCollection 2015.


DEC205+ Dendritic Cell-Targeted Tolerogenic Vaccination Promotes Immune Tolerance in Experimental Autoimmune Arthritis.

Spiering R, Margry B, Keijzer C, Petzold C, Hoek A, Wagenaar-Hilbers J, van der Zee R, van Eden W, Kretschmer K, Broere F.

J Immunol. 2015 May 15;194(10):4804-13. doi: 10.4049/jimmunol.1400986. Epub 2015 Apr 10.


Diet and the anti-inflammatory effect of heat shock proteins.

van Eden W.

Endocr Metab Immune Disord Drug Targets. 2015;15(1):31-6. Review.


[Vaccination during pregnancy: safe or not?].

van Eden W.

Ned Tijdschr Geneeskd. 2014;158:A7293. Review. Dutch.


Inactivated influenza vaccine adjuvanted with bacterium-like particles induce systemic and mucosal influenza A virus specific T-cell and B-cell responses after nasal administration in a TLR2 dependent fashion.

Keijzer C, Haijema BJ, Meijerhof T, Voorn P, de Haan A, Leenhouts K, van Roosmalen ML, van Eden W, Broere F.

Vaccine. 2014 May 19;32(24):2904-10. doi: 10.1016/j.vaccine.2014.02.019. Epub 2014 Mar 2.


Activated peritoneal cavity B-1a cells possess regulatory B cell properties.

Margry B, Kersemakers SC, Hoek A, Arkesteijn GJ, Wieland WH, van Eden W, Broere F.

PLoS One. 2014 Feb 13;9(2):e88869. doi: 10.1371/journal.pone.0088869. eCollection 2014.


T cell recognition of naturally presented epitopes of self-heat shock protein 70.

de Jong H, Koffeman EC, Meerding JM, Scholman RC, Wieten L, de Jager W, Klein M, Otten H, van Wijk F, van der Zee R, Bijlsma JW, Broere F, van Eden W, Prakken BJ.

Cell Stress Chaperones. 2014 Jul;19(4):569-78. doi: 10.1007/s12192-013-0484-1. Epub 2014 Jan 15.


Membrane-bound metallothionein 1 of murine dendritic cells promotes the expansion of regulatory T cells in vitro.

Spiering R, Wagenaar-Hilbers J, Huijgen V, van der Zee R, van Kooten PJ, van Eden W, Broere F.

Toxicol Sci. 2014 Mar;138(1):69-75. doi: 10.1093/toxsci/kft268. Epub 2013 Nov 27.


APL-1, an altered peptide ligand derived from human heat-shock protein 60, selectively induces apoptosis in activated CD4+ CD25+ T cells from peripheral blood of rheumatoid arthritis patients.

Barberá A, Lorenzo N, Garrido G, Mazola Y, Falcón V, Torres AM, Hernández MI, Hernández MV, Margry B, de Groot AM, van Roon J, van der Zee R, Broere F, van Eden W, Padrón G, Domínguez Mdel C.

Int Immunopharmacol. 2013 Dec;17(4):1075-83. doi: 10.1016/j.intimp.2013.10.010. Epub 2013 Oct 29.


Antigen-specific B lymphocytes acquire proteoglycan aggrecan from cartilage extracellular matrix resulting in antigen presentation and CD4+ T-cell activation.

Ciechomska M, Wilson CL, Floudas A, Hui W, Rowan AD, van Eden W, Robinson JH, Knight AM.

Immunology. 2014 Jan;141(1):70-8. doi: 10.1111/imm.12169.


Treg inducing adjuvants for therapeutic vaccination against chronic inflammatory diseases.

Keijzer C, van der Zee R, van Eden W, Broere F.

Front Immunol. 2013 Aug 20;4:245. doi: 10.3389/fimmu.2013.00245. eCollection 2013.


Differential lung NK cell responses in avian influenza virus infected chickens correlate with pathogenicity.

Jansen CA, de Geus ED, van Haarlem DA, van de Haar PM, Löndt BZ, Graham SP, Göbel TW, van Eden W, Brookes SM, Vervelde L.

Sci Rep. 2013;3:2478. doi: 10.1038/srep02478.

Supplemental Content

Loading ...
Support Center