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Role of Critical Care Medicine Training in the Cardiovascular Intensive Care Unit: Survey Responses From Dual Certified Critical Care Cardiologists.

Brusca SB, Barnett C, Barnhart BJ, Weng W, Morrow DA, Soble JS, Katz JN, Wiley BM, van Diepen S, Gomez AD, Solomon MA.

J Am Heart Assoc. 2019 Mar 19;8(6):e011721. doi: 10.1161/JAHA.118.011721.


Epidemiology of Shock in Contemporary Cardiac Intensive Care Units.

Berg DD, Bohula EA, van Diepen S, Katz JN, Alviar CL, Baird-Zars VM, Barnett CF, Barsness GW, Burke JA, Cremer PC, Cruz J, Daniels LB, DeFilippis AP, Haleem A, Hollenberg SM, Horowitz JM, Keller N, Kontos MC, Lawler PR, Menon V, Metkus TS, Ng J, Orgel R, Overgaard CB, Park JG, Phreaner N, Roswell RO, Schulman SP, Jeffrey Snell R, Solomon MA, Ternus B, Tymchak W, Vikram F, Morrow DA.

Circ Cardiovasc Qual Outcomes. 2019 Mar;12(3):e005618. doi: 10.1161/CIRCOUTCOMES.119.005618.


2019 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Guidelines on the Acute Management of ST-Elevation Myocardial Infarction: Focused Update on Regionalization and Reperfusion.

Wong GC, Welsford M, Ainsworth C, Abuzeid W, Fordyce CB, Greene J, Huynh T, Lambert L, Le May M, Lutchmedial S, Mehta SR, Natarajan M, Norris CM, Overgaard CB, Perry Arnesen M, Quraishi A, Tanguay JF, Traboulsi M, van Diepen S, Welsh R, Wood DA, Cantor WJ; members of the Secondary Panel.

Can J Cardiol. 2019 Feb;35(2):107-132. doi: 10.1016/j.cjca.2018.11.031.


Variables Associated With Cardiac Surgical Waitlist Mortality From a Population-Based Cohort.

Senaratne JM, Norris CM, Youngson E, McClure RS, Nagendran J, Butler CR, Meyer SR, Anderson TJ, van Diepen S.

Can J Cardiol. 2019 Jan;35(1):61-67. doi: 10.1016/j.cjca.2018.10.007. Epub 2018 Oct 19.


Patterns of use of targeted temperature management for acute myocardial infarction patients following out-of-hospital cardiac arrest: Insights from the National Cardiovascular Data Registry.

Fordyce CB, Chen AY, Wang TY, Lucas J, Goyal A, Wong GC, van Diepen S, Kontos MC, Henry TD, Granger CB, Roe MT.

Am Heart J. 2018 Dec;206:131-133. doi: 10.1016/j.ahj.2018.08.013. Epub 2018 Sep 24.


Pulmonary capillary blood volume response to exercise is diminished in mild chronic obstructive pulmonary disease.

Tedjasaputra V, van Diepen S, Phillips DB, Wong EYL, Bhutani M, Michaelchuk WW, Bryan TL, Stickland MK.

Respir Med. 2018 Dec;145:57-65. doi: 10.1016/j.rmed.2018.10.015. Epub 2018 Oct 19.


Comparison of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Management Strategies Before Cardiac Surgery: A Pilot Randomized Controlled Registry Trial.

van Diepen S, Norris CM, Zheng Y, Nagendran J, Graham MM, Gaete Ortega D, Townsend DR, Ezekowitz JA, Bagshaw SM.

J Am Heart Assoc. 2018 Oct 16;7(20):e009917. doi: 10.1161/JAHA.118.009917.


Acute Coronary Syndromes and Heart Failure Critical Care Units Utilization and Outcomes in Teaching and Community Hospitals: A National Population-Based Analysis.

Verma S, Kaul P, Lin M, Ezekowitz JA, Zygun DA, Fordyce CB, Wang TY, McAlister FA, van Diepen S.

Can J Cardiol. 2018 Oct;34(10):1365-1368. doi: 10.1016/j.cjca.2018.07.419. Epub 2018 Jul 29.


Positive Pressure Ventilation in the Cardiac Intensive Care Unit.

Alviar CL, Miller PE, McAreavey D, Katz JN, Lee B, Moriyama B, Soble J, van Diepen S, Solomon MA, Morrow DA; ACC Critical Care Cardiology Working Group.

J Am Coll Cardiol. 2018 Sep 25;72(13):1532-1553. doi: 10.1016/j.jacc.2018.06.074. Review.


Maternal cardioautonomic responses during and following exercise throughout pregnancy.

Purdy GM, James MA, Wakefield PK, Skow RJ, Van Diepen S, May LE, Davenport MH, Steinback CD.

Appl Physiol Nutr Metab. 2019 Mar;44(3):263-270. doi: 10.1139/apnm-2018-0397. Epub 2018 Aug 23.


Norepinephrine as a First-Line Inopressor in Cardiogenic Shock: Oversimplification or Best Practice?

van Diepen S.

J Am Coll Cardiol. 2018 Jul 10;72(2):183-186. doi: 10.1016/j.jacc.2018.04.052. No abstract available.


Influence of hospital volume on outcomes for patients with heart failure: Evidence from a Canadian national cohort study.

McAlister FA, Youngson E, van Diepen S, Ezekowitz JA, Kaul P.

Am Heart J. 2018 Aug;202:148-150. doi: 10.1016/j.ahj.2018.05.014. Epub 2018 May 27.


The high cost of critical care unit over-utilization for patients with NSTE ACS.

van Diepen S, Tran DT, Ezekowitz JA, Zygun DA, Katz JN, Lopes RD, Newby LK, McAlister FA, Kaul P.

Am Heart J. 2018 Aug;202:84-88. doi: 10.1016/j.ahj.2018.05.003. Epub 2018 May 19.


Defining an Intraoperative Hypotension Threshold in Association with Stroke in Cardiac Surgery.

Sun LY, Chung AM, Farkouh ME, van Diepen S, Weinberger J, Bourke M, Ruel M.

Anesthesiology. 2018 Sep;129(3):440-447. doi: 10.1097/ALN.0000000000002298.


Management of cardiogenic shock complicating myocardial infarction.

Mebazaa A, Combes A, van Diepen S, Hollinger A, Katz JN, Landoni G, Hajjar LA, Lassus J, Lebreton G, Montalescot G, Park JJ, Price S, Sionis A, Yannopolos D, Harjola VP, Levy B, Thiele H.

Intensive Care Med. 2018 Jun;44(6):760-773. doi: 10.1007/s00134-018-5214-9. Epub 2018 May 16. Review.


Systematic review and directors survey of quality indicators for the cardiovascular intensive care unit.

Goldfarb M, Bibas L, Newby LK, Henry TD, Katz J, van Diepen S, Cercek B.

Int J Cardiol. 2018 Jun 1;260:219-225. doi: 10.1016/j.ijcard.2018.02.113. Epub 2018 Feb 28. Review.


2018 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Focused Update of the Guidelines for the Use of Antiplatelet Therapy.

Mehta SR, Bainey KR, Cantor WJ, Lordkipanidzé M, Marquis-Gravel G, Robinson SD, Sibbald M, So DY, Wong GC, Abunassar JG, Ackman ML, Bell AD, Cartier R, Douketis JD, Lawler PR, McMurtry MS, Udell JA, van Diepen S, Verma S, Mancini GBJ, Cairns JA, Tanguay JF; members of the Secondary Panel.

Can J Cardiol. 2018 Mar;34(3):214-233. doi: 10.1016/j.cjca.2017.12.012. Epub 2017 Dec 19. Review.


Chemoreflex mediated arrhythmia during apnea at 5,050 m in low- but not high-altitude natives.

Busch SA, Davies H, van Diepen S, Simpson LL, Sobierajski F, Riske L, Stembridge M, Ainslie PN, Willie CK, Hoiland R, Moore JP, Steinback CD.

J Appl Physiol (1985). 2018 Apr 1;124(4):930-937. doi: 10.1152/japplphysiol.00774.2017. Epub 2017 Dec 21.


Noncardiovascular Disease and Critical Care Delivery in a Contemporary Cardiac and Medical Intensive Care Unit.

Goldfarb M, van Diepen S, Liszkowski M, Jentzer JC, Pedraza I, Cercek B.

J Intensive Care Med. 2017 Jan 1:885066617741873. doi: 10.1177/0885066617741873. [Epub ahead of print]


Association of Public Health Initiatives With Outcomes for Out-of-Hospital Cardiac Arrest at Home and in Public Locations.

Fordyce CB, Hansen CM, Kragholm K, Dupre ME, Jollis JG, Roettig ML, Becker LB, Hansen SM, Hinohara TT, Corbett CC, Monk L, Nelson RD, Pearson DA, Tyson C, van Diepen S, Anderson ML, McNally B, Granger CB.

JAMA Cardiol. 2017 Nov 1;2(11):1226-1235. doi: 10.1001/jamacardio.2017.3471.


Multistate 5-Year Initiative to Improve Care for Out-of-Hospital Cardiac Arrest: Primary Results From the HeartRescue Project.

van Diepen S, Girotra S, Abella BS, Becker LB, Bobrow BJ, Chan PS, Fahrenbruch C, Granger CB, Jollis JG, McNally B, White L, Yannopoulos D, Rea TD.

J Am Heart Assoc. 2017 Sep 22;6(9). pii: e005716. doi: 10.1161/JAHA.117.005716.


Contemporary Management of Cardiogenic Shock: A Scientific Statement From the American Heart Association.

van Diepen S, Katz JN, Albert NM, Henry TD, Jacobs AK, Kapur NK, Kilic A, Menon V, Ohman EM, Sweitzer NK, Thiele H, Washam JB, Cohen MG; American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Quality of Care and Outcomes Research; and Mission: Lifeline.

Circulation. 2017 Oct 17;136(16):e232-e268. doi: 10.1161/CIR.0000000000000525. Epub 2017 Sep 18. Review.


Clinical and Angiographic Outcomes in Coronary Artery Bypass Surgery with Multiple versus Single Distal Target Grafts.

Alherbish A, Norris CM, Shavadia J, Almutawa M, Abualnaja S, Nagendran J, Graham MM, Van Diepen S.

Heart Surg Forum. 2017 Aug 24;20(4):E132-E138. doi: 10.1532/hsf.1793.


Organizational Structure, Staffing, Resources, and Educational Initiatives in Cardiac Intensive Care Units in the United States: An American Heart Association Acute Cardiac Care Committee and American College of Cardiology Critical Care Cardiology Working Group Cross-Sectional Survey.

van Diepen S, Fordyce CB, Wegermann ZK, Granger CB, Stebbins A, Morrow DA, Solomon MA, Soble J, Henry TD, Gilchrist IC, Katz JN, Cohen MG, Newby LK.

Circ Cardiovasc Qual Outcomes. 2017 Aug;10(8):e003864. doi: 10.1161/CIRCOUTCOMES.117.003864. No abstract available.


Reply: Relevance of Indications for CABG in Evaluating the Effect of Dual Antiplatelet Therapy.

van Diepen S, Fuster V, Farkouh ME.

J Am Coll Cardiol. 2017 Jul 25;70(4):508-509. doi: 10.1016/j.jacc.2017.04.063. No abstract available.


Characterization of hemodynamically stable acute heart failure patients requiring a critical care unit admission: Derivation, validation, and refinement of a risk score.

Raslan IR, Brown P, Westerhout CM, Ezekowitz JA, Hernandez AF, Starling RC, O'Connor C, McAlister FA, Rowe BH, Armstrong PW, van Diepen S.

Am Heart J. 2017 Jun;188:127-135. doi: 10.1016/j.ahj.2017.03.014. Epub 2017 Mar 25.


Length of Stay, Mortality, Cost, and Perceptions of Care Associated With Transition From an Open to Closed Staffing Model in the Cardiac Intensive Care Unit.

Katz JN, Lishmanov A, van Diepen S, Yu D, Shen H, Pauley E, Bhatia J, Buntaine A, Das A, Dangerfield C, McLaughlin B, Stouffer GA, Kaul P.

Crit Pathw Cardiol. 2017 Jun;16(2):62-70. doi: 10.1097/HPC.0000000000000104.


Postoperative Complications and Outcomes Associated With a Transition to 24/7 Intensivist Management of Cardiac Surgery Patients.

Benoit MA, Bagshaw SM, Norris CM, Zibdawi M, Chin WD, Ross DB, van Diepen S.

Crit Care Med. 2017 Jun;45(6):993-1000. doi: 10.1097/CCM.0000000000002434.


Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery.

Mehta RH, Leimberger JD, van Diepen S, Meza J, Wang A, Jankowich R, Harrison RW, Hay D, Fremes S, Duncan A, Soltesz EG, Luber J, Park S, Argenziano M, Murphy E, Marcel R, Kalavrouziotis D, Nagpal D, Bozinovski J, Toller W, Heringlake M, Goodman SG, Levy JH, Harrington RA, Anstrom KJ, Alexander JH; LEVO-CTS Investigators.

N Engl J Med. 2017 May 25;376(21):2032-2042. doi: 10.1056/NEJMoa1616218. Epub 2017 Mar 19.


Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise.

Tedjasaputra V, van Diepen S, Collins SÉ, Michaelchuk WM, Stickland MK.

J Vis Exp. 2017 Feb 20;(120). doi: 10.3791/54949.


Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery.

van Diepen S, Merrill PD, Carrier M, Tardif JC, Podgoreanu M, Alexander JH, Lopes RD.

J Thromb Thrombolysis. 2017 May;43(4):446-453. doi: 10.1007/s11239-017-1480-6.


Dual Antiplatelet Therapy Versus Aspirin Monotherapy in Diabetics With Multivessel Disease Undergoing CABG: FREEDOM Insights.

van Diepen S, Fuster V, Verma S, Hamza TH, Siami FS, Goodman SG, Farkouh ME.

J Am Coll Cardiol. 2017 Jan 17;69(2):119-127. doi: 10.1016/j.jacc.2016.10.043.


Canadian Cardiovascular Society/Canadian Cardiovascular Critical Care Society/Canadian Association of Interventional Cardiology Position Statement on the Optimal Care of the Postarrest Patient.

Wong GC, van Diepen S, Ainsworth C, Arora RC, Diodati JG, Liszkowski M, Love M, Overgaard C, Schnell G, Tanguay JF, Wells G, Le May M; CCS Post Cardiac Arrest Guidelines Committee.

Can J Cardiol. 2017 Jan;33(1):1-16. doi: 10.1016/j.cjca.2016.10.021. Epub 2016 Nov 3. Review.


Interprovincial Differences in Canadian Coronary Care Unit Resource Use and Outcomes.

van Diepen S, Lin M, Ezekowitz JA, McAlister FA, Lee DS, Goodman SG, Armstrong PW, Kaul P.

Can J Cardiol. 2017 Jan;33(1):166-169. doi: 10.1016/j.cjca.2016.10.009. Epub 2016 Oct 19.


Levosimendan in patients with left ventricular systolic dysfunction undergoing cardiac surgery on cardiopulmonary bypass: Rationale and study design of the Levosimendan in Patients with Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery Requiring Cardiopulmonary Bypass (LEVO-CTS) trial.

Mehta RH, Van Diepen S, Meza J, Bokesch P, Leimberger JD, Tourt-Uhlig S, Swartz M, Parrotta J, Jankowich R, Hay D, Harrison RW, Fremes S, Goodman SG, Luber J, Toller W, Heringlake M, Anstrom KJ, Levy JH, Harrington RA, Alexander JH; LEVO-CTS Investigators.

Am Heart J. 2016 Dec;182:62-71. doi: 10.1016/j.ahj.2016.09.001. Epub 2016 Sep 9.


Prevention of Critical Care Complications in the Coronary Intensive Care Unit: Protocols, Bundles, and Insights From Intensive Care Studies.

van Diepen S, Sligl WI, Washam JB, Gilchrist IC, Arora RC, Katz JN.

Can J Cardiol. 2017 Jan;33(1):101-109. doi: 10.1016/j.cjca.2016.06.011. Epub 2016 Jul 1. Review.


The Genesis, Maturation, and Future of Critical Care Cardiology.

Katz JN, Minder M, Olenchock B, Price S, Goldfarb M, Washam JB, Barnett CF, Newby LK, van Diepen S.

J Am Coll Cardiol. 2016 Jul 5;68(1):67-79. doi: 10.1016/j.jacc.2016.04.036. Review.


Temporal changes in biomarkers and their relationships to reperfusion and to clinical outcomes among patients with ST segment elevation myocardial infarction.

van Diepen S, Alemayehu WG, Zheng Y, Theroux P, Newby LK, Mahaffey KW, Granger CB, Armstrong PW.

J Thromb Thrombolysis. 2016 Oct;42(3):376-85. doi: 10.1007/s11239-016-1390-z.


Do stable non-ST-segment elevation acute coronary syndromes require admission to coronary care units?

van Diepen S, Lin M, Bakal JA, McAlister FA, Kaul P, Katz JN, Fordyce CB, Southern DA, Graham MM, Wilton SB, Newby LK, Granger CB, Ezekowitz JA.

Am Heart J. 2016 May;175:184-92. doi: 10.1016/j.ahj.2015.11.020. Epub 2016 Jan 23.


Regional Variation in Out-of-Hospital Cardiac Arrest Survival in the United States.

Girotra S, van Diepen S, Nallamothu BK, Carrel M, Vellano K, Anderson ML, McNally B, Abella BS, Sasson C, Chan PS; CARES Surveillance Group and the HeartRescue Project.

Circulation. 2016 May 31;133(22):2159-68. doi: 10.1161/CIRCULATIONAHA.115.018175. Epub 2016 Apr 14.


From Coronary Care Units to Cardiac Intensive Care Units: Recommendations for Organizational, Staffing, and Educational Transformation.

Le May M, van Diepen S, Liszkowski M, Schnell G, Tanguay JF, Granger CB, Ainsworth C, Diodati JG, Fam N, Haichin R, Jassal D, Overgaard C, Tymchak W, Tyrrell B, Osborne C, Wong G.

Can J Cardiol. 2016 Oct;32(10):1204-1213. doi: 10.1016/j.cjca.2015.11.021. Epub 2015 Dec 8.


Renal failure in patients with ST-segment elevation acute myocardial infarction treated with primary percutaneous coronary intervention: Predictors, clinical and angiographic features, and outcomes.

Vavalle JP, van Diepen S, Clare RM, Hochman JS, Weaver WD, Mehta RH, Pieper KS, Patel MR, Patel UD, Armstrong PW, Granger CB, Lopes RD.

Am Heart J. 2016 Mar;173:57-66. doi: 10.1016/j.ahj.2015.12.001. Epub 2015 Dec 11.


Successful inter-hospital transfer for extracorporeal membrane oxygenation after an amniotic fluid embolism induced cardiac arrest.

Fang ZA, Van Diepen S; Royal Alexandra Hospital and University of Alberta Hospital Cardiac Arrest Teams.

Can J Anaesth. 2016 Apr;63(4):507-8. doi: 10.1007/s12630-015-0548-z. Epub 2016 Jan 29. No abstract available.


Clinical and angiographic outcomes associated with surgical revascularization of angiographically borderline 50-69% coronary artery stenoses.

Senaratne JM, Norris CM, Graham MM, Galbraith D, Nagendran J, Freed DH, Afilalo J, Van Diepen S; APPROACH Investigators.

Eur J Cardiothorac Surg. 2016 May;49(5):e112-8. doi: 10.1093/ejcts/ezw005. Epub 2016 Jan 29.


Efficacy and Safety of Vorapaxar in Non-ST-Segment Elevation Acute Coronary Syndrome Patients Undergoing Noncardiac Surgery.

van Diepen S, Tricoci P, Podder M, Westerhout CM, Aylward PE, Held C, Van de Werf F, Strony J, Wallentin L, Moliterno DJ, White HD, Mahaffey KW, Harrington RA, Armstrong PW.

J Am Heart Assoc. 2015 Dec 15;4(12). pii: e002546. doi: 10.1161/JAHA.115.002546.


Delirium is a robust predictor of morbidity and mortality among critically ill patients treated in the cardiac intensive care unit.

Pauley E, Lishmanov A, Schumann S, Gala GJ, van Diepen S, Katz JN.

Am Heart J. 2015 Jul;170(1):79-86, 86.e1. doi: 10.1016/j.ahj.2015.04.013. Epub 2015 Apr 17.


Is coronary intensive care unit volume a quality metric?

van Diepen S.

J Am Heart Assoc. 2015 Jun 11;4(6):002200. doi: 10.1161/JAHA.115.002200. No abstract available.


Cardiovascular Critical Care: A Perceived Deficiency Among U.S. Trainees.

Hill T, Means G, van Diepen S, Paul T, Katz JN.

Crit Care Med. 2015 Sep;43(9):1853-8. doi: 10.1097/CCM.0000000000001074.


Dopamine receptor blockade improves pulmonary gas exchange but decreases exercise performance in healthy humans.

Tedjasaputra V, Bryan TL, van Diepen S, Moore LE, Bouwsema MM, Welsh RC, Petersen SR, Stickland MK.

J Physiol. 2015 Jul 15;593(14):3147-57. doi: 10.1113/JP270238. Epub 2015 Jun 8.


Variation in critical care unit admission rates and outcomes for patients with acute coronary syndromes or heart failure among high- and low-volume cardiac hospitals.

van Diepen S, Bakal JA, Lin M, Kaul P, McAlister FA, Ezekowitz JA.

J Am Heart Assoc. 2015 Feb 27;4(3):e001708. doi: 10.1161/JAHA.114.001708.

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