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Items: 5

1.

CRISPR/Cas9, a powerful tool to target human herpesviruses.

van Diemen FR, Lebbink RJ.

Cell Microbiol. 2017 Feb;19(2). doi: 10.1111/cmi.12694. Epub 2016 Dec 23. Review.

PMID:
27860066
2.

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections.

van Diemen FR, Kruse EM, Hooykaas MJ, Bruggeling CE, Schürch AC, van Ham PM, Imhof SM, Nijhuis M, Wiertz EJ, Lebbink RJ.

PLoS Pathog. 2016 Jun 30;12(6):e1005701. doi: 10.1371/journal.ppat.1005701. eCollection 2016 Jun.

3.

Gene essentiality and synthetic lethality in haploid human cells.

Blomen VA, Májek P, Jae LT, Bigenzahn JW, Nieuwenhuis J, Staring J, Sacco R, van Diemen FR, Olk N, Stukalov A, Marceau C, Janssen H, Carette JE, Bennett KL, Colinge J, Superti-Furga G, Brummelkamp TR.

Science. 2015 Nov 27;350(6264):1092-6. doi: 10.1126/science.aac7557. Epub 2015 Oct 15.

4.

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome.

Tsvetkov P, Mendillo ML, Zhao J, Carette JE, Merrill PH, Cikes D, Varadarajan M, van Diemen FR, Penninger JM, Goldberg AL, Brummelkamp TR, Santagata S, Lindquist S.

Elife. 2015 Sep 1;4. doi: 10.7554/eLife.08467.

5.

LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins.

Schorch B, Song S, van Diemen FR, Bock HH, May P, Herz J, Brummelkamp TR, Papatheodorou P, Aktories K.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6431-6. doi: 10.1073/pnas.1323790111. Epub 2014 Apr 15.

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