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Items: 1 to 50 of 127

1.

Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression.

Ren J, Smid M, Iaria J, Salvatori DCF, van Dam H, Zhu HJ, Martens JWM, Ten Dijke P.

Breast Cancer Res. 2019 Sep 18;21(1):109. doi: 10.1186/s13058-019-1194-0.

2.

VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation.

Li Y, Cui C, Xie F, Kiełbasa S, Mei H, van Dinther M, van Dam H, Bauer A, Zhang L, Ten Dijke P.

J Mol Cell Biol. 2019 Jul 10. pii: mjz057. doi: 10.1093/jmcb/mjz057. [Epub ahead of print]

PMID:
31291647
3.

Squamous cell carcinoma arising from a nasojugal cyst.

Cantwell P, Van Dam H.

Med J Aust. 2019 Aug;211(4):165-165.e1. doi: 10.5694/mja2.50254. Epub 2019 Jun 28. No abstract available.

PMID:
31250921
4.

Acral Amelanotic Melanoma Mimicking a Non-Healing Arterial Ulcer.

Cantwell P, Van Dam H.

Case Rep Dermatol. 2019 Mar 28;11(1):77-81. doi: 10.1159/000499155. eCollection 2019 Jan-Apr.

5.

Advance care planning conversations with palliative patients: looking through the GP's eyes.

Wichmann AB, van Dam H, Thoonsen B, Boer TA, Engels Y, Groenewoud AS.

BMC Fam Pract. 2018 Nov 28;19(1):184. doi: 10.1186/s12875-018-0868-5.

6.

FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral Infection.

Dai T, Wu L, Wang S, Wang J, Xie F, Zhang Z, Fang X, Li J, Fang P, Li F, Jin K, Dai J, Yang B, Zhou F, van Dam H, Cai D, Huang H, Zhang L.

Cell Host Microbe. 2018 Dec 12;24(6):776-790.e5. doi: 10.1016/j.chom.2018.10.006. Epub 2018 Nov 21.

PMID:
30472208
7.

OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.

Zhang Z, Du J, Wang S, Shao L, Jin K, Li F, Wei B, Ding W, Fu P, van Dam H, Wang A, Jin J, Ding C, Yang B, Zheng M, Feng XH, Guan KL, Zhang L.

Mol Cell. 2019 Jan 3;73(1):7-21.e7. doi: 10.1016/j.molcel.2018.10.030. Epub 2018 Nov 21.

PMID:
30472188
8.

Inflammation induces endothelial-to-mesenchymal transition and promotes vascular calcification through downregulation of BMPR2.

Sánchez-Duffhues G, García de Vinuesa A, van de Pol V, Geerts ME, de Vries MR, Janson SG, van Dam H, Lindeman JH, Goumans MJ, Ten Dijke P.

J Pathol. 2019 Mar;247(3):333-346. doi: 10.1002/path.5193. Epub 2019 Jan 16.

9.

Epithelial-mesenchymal-transition-inducing transcription factors: new targets for tackling chemoresistance in cancer?

van Staalduinen J, Baker D, Ten Dijke P, van Dam H.

Oncogene. 2018 Nov;37(48):6195-6211. doi: 10.1038/s41388-018-0378-x. Epub 2018 Jul 12. Review.

PMID:
30002444
10.

Tumor-derived exosomes antagonize innate antiviral immunity.

Gao L, Wang L, Dai T, Jin K, Zhang Z, Wang S, Xie F, Fang P, Yang B, Huang H, van Dam H, Zhou F, Zhang L.

Nat Immunol. 2018 Mar;19(3):233-245. doi: 10.1038/s41590-017-0043-5. Epub 2018 Jan 22.

PMID:
29358709
11.

Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7.

Zhang Z, Fan Y, Xie F, Zhou H, Jin K, Shao L, Shi W, Fang P, Yang B, van Dam H, Ten Dijke P, Zheng X, Yan X, Jia J, Zheng M, Jin J, Ding C, Ye S, Zhou F, Zhang L.

Nat Commun. 2017 Dec 13;8(1):2116. doi: 10.1038/s41467-017-02029-7.

12.

TGF-β signaling in cancer metastasis.

Xie F, Ling L, van Dam H, Zhou F, Zhang L.

Acta Biochim Biophys Sin (Shanghai). 2018 Jan 1;50(1):121-132. doi: 10.1093/abbs/gmx123. Review.

PMID:
29190313
13.

JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion.

Sundqvist A, Morikawa M, Ren J, Vasilaki E, Kawasaki N, Kobayashi M, Koinuma D, Aburatani H, Miyazono K, Heldin CH, van Dam H, Ten Dijke P.

Nucleic Acids Res. 2018 Feb 16;46(3):1180-1195. doi: 10.1093/nar/gkx1190.

14.

Corrigendum: YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKKɛ-mediated phosphorylation.

Wang S, Xie F, Chu F, Zhang Z, Yang B, Dai T, Gao L, Wang L, Ling L, Jia J, van Dam H, Jin J, Zhang L, Zhou F.

Nat Immunol. 2017 Oct 18;18(11):1270. doi: 10.1038/ni1117-1270d.

PMID:
29044228
15.

YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKKɛ-mediated phosphorylation.

Wang S, Xie F, Chu F, Zhang Z, Yang B, Dai T, Gao L, Wang L, Ling L, Jia J, van Dam H, Jin J, Zhang L, Zhou F.

Nat Immunol. 2017 Jul;18(7):733-743. doi: 10.1038/ni.3744. Epub 2017 May 8. Erratum in: Nat Immunol. 2017 Oct 18;18(11):1270.

PMID:
28481329
16.

FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis.

Xie F, Jin K, Shao L, Fan Y, Tu Y, Li Y, Yang B, van Dam H, Ten Dijke P, Weng H, Dooley S, Wang S, Jia J, Jin J, Zhou F, Zhang L.

Nat Commun. 2017 Apr 26;8:15021. doi: 10.1038/ncomms15021.

17.

Molecular insights into tumour metastasis: tracing the dominant events.

Jin K, Li T, van Dam H, Zhou F, Zhang L.

J Pathol. 2017 Apr;241(5):567-577. doi: 10.1002/path.4871. Epub 2017 Mar 7. Review.

PMID:
28035672
18.

Ubiquitin-Specific Protease 4 Antagonizes Osteoblast Differentiation Through Dishevelled.

Zhou F, Li F, Fang P, Dai T, Yang B, van Dam H, Jia J, Zheng M, Zhang L.

J Bone Miner Res. 2016 Oct;31(10):1888-1898. doi: 10.1002/jbmr.2863. Epub 2016 May 20.

19.

c-Myb Enhances Breast Cancer Invasion and Metastasis through the Wnt/β-Catenin/Axin2 Pathway.

Li Y, Jin K, van Pelt GW, van Dam H, Yu X, Mesker WE, Ten Dijke P, Zhou F, Zhang L.

Cancer Res. 2016 Jun 1;76(11):3364-75. doi: 10.1158/0008-5472.CAN-15-2302. Epub 2016 Apr 5.

20.

Regulation of the TGF-β pathway by deubiquitinases in cancer.

Liu S, de Boeck M, van Dam H, Ten Dijke P.

Int J Biochem Cell Biol. 2016 Jul;76:135-45. doi: 10.1016/j.biocel.2016.05.001. Epub 2016 May 4. Review.

PMID:
27155333
21.

Describing Excited State Relaxation and Localization in TiO2 Nanoparticles Using TD-DFT.

Berardo E, Hu HS, van Dam HJ, Shevlin SA, Woodley SM, Kowalski K, Zwijnenburg MA.

J Chem Theory Comput. 2014 Dec 9;10(12):5538-48. doi: 10.1021/ct500787x. Epub 2014 Nov 17.

PMID:
26583237
22.

Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2.

Carthy JM, Sundqvist A, Heldin A, van Dam H, Kletsas D, Heldin CH, Moustakas A.

J Cell Physiol. 2015 Dec;230(12):3084-92. doi: 10.1002/jcp.25049.

PMID:
26096876
23.

Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models.

Li Y, Drabsch Y, Pujuguet P, Ren J, van Laar T, Zhang L, van Dam H, Clément-Lacroix P, Ten Dijke P.

Breast Cancer Res. 2015 Feb 25;17:28. doi: 10.1186/s13058-015-0537-8.

24.

14-3-3ζ turns TGF-β to the dark side.

ten Dijke P, van Dam H.

Cancer Cell. 2015 Feb 9;27(2):151-3. doi: 10.1016/j.ccell.2015.01.005.

25.

Regulation of TGF-β Superfamily Signaling by SMAD Mono-Ubiquitination.

Xie F, Zhang Z, van Dam H, Zhang L, Zhou F.

Cells. 2014 Oct 15;3(4):981-93. doi: 10.3390/cells3040981. Review.

26.

The regulation of TGF-β/SMAD signaling by protein deubiquitination.

Zhang J, Zhang X, Xie F, Zhang Z, van Dam H, Zhang L, Zhou F.

Protein Cell. 2014 Jul;5(7):503-17. doi: 10.1007/s13238-014-0058-8. Epub 2014 Apr 23. Review.

27.

Avoidance of recurrence of CRPS Type 1 in individuals requiring further surgery for Dupuytren's contracture.

Van Dam H, Elliot D.

J Plast Reconstr Aesthet Surg. 2014 Jun;67(6):878-9. doi: 10.1016/j.bjps.2013.12.024. Epub 2013 Dec 31. No abstract available.

PMID:
24529691
28.

Simulating One-Photon Absorption and Resonance Raman Scattering Spectra Using Analytical Excited State Energy Gradients within Time-Dependent Density Functional Theory.

Silverstein DW, Govind N, van Dam HJ, Jensen L.

J Chem Theory Comput. 2013 Dec 10;9(12):5490-503. doi: 10.1021/ct4007772. Epub 2013 Nov 23.

PMID:
26592284
29.

A Case for Soft Error Detection and Correction in Computational Chemistry.

van Dam HJ, Vishnu A, de Jong WA.

J Chem Theory Comput. 2013 Sep 10;9(9):3995-4005. doi: 10.1021/ct400489c. Epub 2013 Aug 13.

PMID:
26592395
30.

Sub-200 ps CRT in monolithic scintillator PET detectors using digital SiPM arrays and maximum likelihood interaction time estimation.

van Dam HT, Borghi G, Seifert S, Schaart DR.

Phys Med Biol. 2013 May 21;58(10):3243-57. doi: 10.1088/0031-9155/58/10/3243. Epub 2013 Apr 24.

PMID:
23611889
31.

First characterization of a digital SiPM based time-of-flight PET detector with 1 mm spatial resolution.

Seifert S, van der Lei G, van Dam HT, Schaart DR.

Phys Med Biol. 2013 May 7;58(9):3061-74. doi: 10.1088/0031-9155/58/9/3061. Epub 2013 Apr 15.

PMID:
23587636
32.

Noniterative Multireference Coupled Cluster Methods on Heterogeneous CPU-GPU Systems.

Bhaskaran-Nair K, Ma W, Krishnamoorthy S, Villa O, van Dam HJ, Aprà E, Kowalski K.

J Chem Theory Comput. 2013 Apr 9;9(4):1949-57. doi: 10.1021/ct301130u. Epub 2013 Mar 19.

PMID:
26583545
33.

UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination.

Zhang X, Zhang J, Zhang L, van Dam H, ten Dijke P.

Cell Res. 2013 Mar;23(3):366-77. doi: 10.1038/cr.2013.21. Epub 2013 Feb 5.

34.

Simulating Silicon Photomultiplier Response to Scintillation Light.

Jha AK, van Dam HT, Kupinski MA, Clarkson E.

IEEE Trans Nucl Sci. 2013 Feb;30(1):336-351.

35.

Implementation of the multireference Brillouin-Wigner and Mukherjee's coupled cluster methods with non-iterative triple excitations utilizing reference-level parallelism.

Bhaskaran-Nair K, Brabec J, Aprà E, van Dam HJ, Pittner J, Kowalski K.

J Chem Phys. 2012 Sep 7;137(9):094112.

PMID:
22957560
36.

Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion.

Sundqvist A, Zieba A, Vasilaki E, Herrera Hidalgo C, Söderberg O, Koinuma D, Miyazono K, Heldin CH, Landegren U, Ten Dijke P, van Dam H.

Oncogene. 2013 Aug 1;32(31):3606-15. doi: 10.1038/onc.2012.370. Epub 2012 Aug 27.

PMID:
22926518
37.

Free jejunum reconstruction of upper esophageal defects.

Laing TA, Van Dam H, Rakshit K, Dilkes M, Ghufoor K, Patel H.

Microsurgery. 2013 Jan;33(1):3-8. doi: 10.1002/micr.21992. Epub 2012 Jul 23.

PMID:
22821641
38.

The statistical distribution of the number of counted scintillation photons in digital silicon photomultipliers: model and validation.

van Dam HT, Seifert S, Schaart DR.

Phys Med Biol. 2012 Aug 7;57(15):4885-903. doi: 10.1088/0031-9155/57/15/4885. Epub 2012 Jul 13.

PMID:
22796633
39.

Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradation.

Zhang L, Zhou F, Li Y, Drabsch Y, Zhang J, van Dam H, ten Dijke P.

J Biol Chem. 2012 Aug 31;287(36):30701-10. doi: 10.1074/jbc.M112.353524. Epub 2012 Jun 22.

40.

RNF12 controls embryonic stem cell fate and morphogenesis in zebrafish embryos by targeting Smad7 for degradation.

Zhang L, Huang H, Zhou F, Schimmel J, Pardo CG, Zhang T, Barakat TS, Sheppard KA, Mickanin C, Porter JA, Vertegaal AC, van Dam H, Gribnau J, Lu CX, ten Dijke P.

Mol Cell. 2012 Jun 8;46(5):650-61. doi: 10.1016/j.molcel.2012.04.003. Epub 2012 May 3. Erratum in: Mol Cell. 2012 Jul 27;47(2):330.

41.

Universal state-selective corrections to multi-reference coupled-cluster theories with single and double excitations.

Brabec J, van Dam HJ, Pittner J, Kowalski K.

J Chem Phys. 2012 Mar 28;136(12):124102. doi: 10.1063/1.3692969.

PMID:
22462830
42.

Monolithic LaBr₃:Ce crystals on silicon photomultiplier arrays for time-of-flight positron emission tomography.

Seifert S, van Dam HT, Huizenga J, Vinke R, Dendooven P, Löhner H, Schaart DR.

Phys Med Biol. 2012 Apr 21;57(8):2219-33. doi: 10.1088/0031-9155/57/8/2219. Epub 2012 Mar 29.

PMID:
22455977
43.

The lower bound on the timing resolution of scintillation detectors.

Seifert S, van Dam HT, Schaart DR.

Phys Med Biol. 2012 Apr 7;57(7):1797-814. doi: 10.1088/0031-9155/57/7/1797. Epub 2012 Mar 13.

PMID:
22410975
44.

Parallel Implementation of Multireference Coupled-Cluster Theories Based on the Reference-Level Parallelism.

Brabec J, Pittner J, van Dam HJ, Aprà E, Kowalski K.

J Chem Theory Comput. 2012 Feb 14;8(2):487-97. doi: 10.1021/ct200809m. Epub 2012 Feb 1.

PMID:
26596599
45.

Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity.

Sundqvist A, Ten Dijke P, van Dam H.

Breast Cancer Res. 2012 Feb 8;14(1):204. Review.

46.

Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation.

Zhou F, Zhang X, van Dam H, Ten Dijke P, Huang H, Zhang L.

J Biol Chem. 2012 Mar 30;287(14):11002-10. doi: 10.1074/jbc.M111.328187. Epub 2012 Jan 19.

47.

BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β(3) expression.

Naber HP, Wiercinska E, Pardali E, van Laar T, Nirmala E, Sundqvist A, van Dam H, van der Horst G, van der Pluijm G, Heckmann B, Danen EH, Ten Dijke P.

Cell Oncol (Dordr). 2012 Feb;35(1):19-28. doi: 10.1007/s13402-011-0058-0. Epub 2011 Sep 21.

48.

GSK3β inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb.

Zhou F, Zhang L, van Laar T, van Dam H, Ten Dijke P.

Mol Biol Cell. 2011 Sep;22(18):3533-40. doi: 10.1091/mbc.E11-06-0483. Epub 2011 Jul 27.

49.

A practical method for depth of interaction determination in monolithic scintillator PET detectors.

van Dam HT, Seifert S, Vinke R, Dendooven P, Löhner H, Beekman FJ, Schaart DR.

Phys Med Biol. 2011 Jul 7;56(13):4135-45. doi: 10.1088/0031-9155/56/13/025. Epub 2011 Jun 21.

PMID:
21693789
50.

Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation.

Zhang L, Zhou F, van Laar T, Zhang J, van Dam H, Ten Dijke P.

Mol Biol Cell. 2011 May;22(9):1617-24. doi: 10.1091/mbc.E10-12-0985. Epub 2011 Mar 16.

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