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Items: 1 to 50 of 277


Coagulopathy After Synthetic Cannabinoid Use: A Case Report.

Rasin A, Devgun JM, Nosal DG, Meehan TJ, van Breemen RB, Thompson TM.

Ann Intern Med. 2019 Aug 27. doi: 10.7326/L19-0321. [Epub ahead of print] No abstract available.


Correction to The Multiple Biological Targets of Hops and Bioactive Compounds.

Bolton JL, Dunlap TL, Hajirahimkhan A, Mbachu O, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM.

Chem Res Toxicol. 2019 Aug 19;32(8):1732. doi: 10.1021/acs.chemrestox.9b00300. Epub 2019 Aug 8. No abstract available.


Ion mobility-mass spectrometry for the separation and analysis of procyanidins.

Rue EA, Glinski JA, Glinski VB, van Breemen RB.

J Mass Spectrom. 2019 May 30. doi: 10.1002/jms.4377. [Epub ahead of print]


The Multiple Biological Targets of Hops and Bioactive Compounds.

Bolton JL, Dunlap TL, Hajirahimkhan A, Mbachu O, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM.

Chem Res Toxicol. 2019 Feb 18;32(2):222-233. doi: 10.1021/acs.chemrestox.8b00345. Epub 2019 Jan 22. Erratum in: Chem Res Toxicol. 2019 Aug 19;32(8):1732.


Finding the bad actor: Challenges in identifying toxic constituents in botanical dietary supplements.

Roberts GK, Gardner D, Foster PM, Howard PC, Lui E, Walker L, van Breemen RB, Auerbach SS, Rider C.

Food Chem Toxicol. 2019 Feb;124:431-438. doi: 10.1016/j.fct.2018.12.026. Epub 2018 Dec 21. Review.


Evidence for Chemopreventive and Resilience Activity of Licorice: Glycyrrhiza Glabra and G. Inflata Extracts Modulate Estrogen Metabolism in ACI Rats.

Wang S, Dunlap TL, Huang L, Liu Y, Simmler C, Lantvit DD, Crosby J, Howell CE, Dong H, Chen SN, Pauli GF, van Breemen RB, Dietz BM, Bolton JL.

Cancer Prev Res (Phila). 2018 Dec;11(12):819-830. doi: 10.1158/1940-6207.CAPR-18-0178. Epub 2018 Oct 4.


Rapid Determination of Procyanidins Using MALDI-ToF/ToF Mass Spectrometry.

Rush MD, Rue EA, Wong A, Kowalski P, Glinski JA, van Breemen RB.

J Agric Food Chem. 2018 Oct 31;66(43):11355-11361. doi: 10.1021/acs.jafc.8b04258. Epub 2018 Oct 16.


Analysis of lanthionine ketimine ethyl ester in mouse serum, whole blood and tissues using ultrahigh-pressure liquid chromatography/tandem mass spectrometry.

Muchiri RN, Kowal KE, Hensley K, Feinstein DL, van Breemen RB.

Rapid Commun Mass Spectrom. 2018 Nov 30;32(22):1941-1948. doi: 10.1002/rcm.8263.


Matrix-Assisted Laser Desorption/Ionization Imaging Portrays Locoregional Drug Delivery.

Gaba RC, Kowalski PJ, van Breemen RB.

J Vasc Interv Radiol. 2018 Aug;29(8):1109. doi: 10.1016/j.jvir.2017.12.003. No abstract available.


Procyanidins: a comprehensive review encompassing structure elucidation via mass spectrometry.

Rue EA, Rush MD, van Breemen RB.

Phytochem Rev. 2018 Feb;17(1):1-16. doi: 10.1007/s11101-017-9507-3. Epub 2017 May 9.


Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication.

Hajirahimkhan A, Mbachu O, Simmler C, Ellis SG, Dong H, Nikolic D, Lankin DC, van Breemen RB, Chen SN, Pauli GF, Dietz BM, Bolton JL.

J Nat Prod. 2018 Apr 27;81(4):966-975. doi: 10.1021/acs.jnatprod.7b01070. Epub 2018 Apr 11.


Analysis of age-related changes in psychosine metabolism in the human brain.

Marshall MS, Jakubauskas B, Bogue W, Stoskute M, Hauck Z, Rue E, Nichols M, DiAntonio LL, van Breemen RB, Kordower JH, Saavedra-Matiz CA, Bongarzone ER.

PLoS One. 2018 Feb 26;13(2):e0193438. doi: 10.1371/journal.pone.0193438. eCollection 2018.


Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy.

Marshall MS, Issa Y, Jakubauskas B, Stoskute M, Elackattu V, Marshall JN, Bogue W, Nguyen D, Hauck Z, Rue E, Karumuthil-Melethil S, Zaric V, Bosland M, van Breemen RB, Givogri MI, Gray SJ, Crocker SJ, Bongarzone ER.

Mol Ther. 2018 Mar 7;26(3):874-889. doi: 10.1016/j.ymthe.2018.01.009. Epub 2018 Jan 17.


Does doxorubicin survive thermal ablation? Results of an ex vivo bench top study.

Morrison JD, Schlager CK, Lee AE, van Breemen RB, Gaba RC.

Diagn Interv Radiol. 2018 Jan-Feb;24(1):28-30. doi: 10.5152/dir.2018.17382.


Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry.

Huang L, Nikolic D, van Breemen RB.

Anal Bioanal Chem. 2017 Dec;409(30):6937-6948. doi: 10.1007/s00216-017-0642-x. Epub 2017 Nov 10.


Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats.

Keiler AM, Macejova D, Dietz BM, Bolton JL, Pauli GF, Chen SN, van Breemen RB, Nikolic D, Goerl F, Muders MH, Zierau O, Vollmer G.

J Steroid Biochem Mol Biol. 2017 Nov;174:234-241. doi: 10.1016/j.jsbmb.2017.09.020. Epub 2017 Sep 28.


A standardized Humulus lupulus (L.) ethanol extract partially prevents ovariectomy-induced bone loss in the rat without induction of adverse effects in the uterus.

Keiler AM, Helle J, Bader MI, Ehrhardt T, Nestler K, Kretzschmar G, Bernhardt R, Vollmer G, Nikolić D, Bolton JL, Pauli GF, Chen SN, Dietz BM, van Breemen RB, Zierau O.

Phytomedicine. 2017 Oct 15;34:50-58. doi: 10.1016/j.phymed.2017.08.001. Epub 2017 Aug 2.


DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women's Health.

Dietz BM, Chen SN, Alvarenga RFR, Dong H, Nikolić D, Biendl M, van Breemen RB, Bolton JL, Pauli GF.

J Nat Prod. 2017 Aug 25;80(8):2284-2294. doi: 10.1021/acs.jnatprod.7b00284. Epub 2017 Aug 16.


Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents.

Li G, Simmler C, Chen L, Nikolic D, Chen SN, Pauli GF, van Breemen RB.

Eur J Pharm Sci. 2017 Nov 15;109:182-190. doi: 10.1016/j.ejps.2017.07.034. Epub 2017 Jul 31.


Prostate Cancer Risk and DNA Methylation Signatures in Aging Rats following Developmental BPA Exposure: A Dose-Response Analysis.

Prins GS, Ye SH, Birch L, Zhang X, Cheong A, Lin H, Calderon-Gierszal E, Groen J, Hu WY, Ho SM, van Breemen RB.

Environ Health Perspect. 2017 Jul 11;125(7):077007. doi: 10.1289/EHP1050.


Isolation and structural characterization of dihydrobenzofuran congeners of licochalcone A.

Simmler C, Lankin DC, Nikolić D, van Breemen RB, Pauli GF.

Fitoterapia. 2017 Sep;121:6-15. doi: 10.1016/j.fitote.2017.06.017. Epub 2017 Jun 21.


Collision-induced dissociation of phenethylamides: role of ion-neutral complexes.

Nikolić D, Macias C, Lankin DC, van Breemen RB.

Rapid Commun Mass Spectrom. 2017 Sep 15;31(17):1385-1395. doi: 10.1002/rcm.7915.


Development of a Magnetic Microbead Affinity Selection Screen (MagMASS) Using Mass Spectrometry for Ligands to the Retinoid X Receptor-α.

Rush MD, Walker EM, Prehna G, Burton T, van Breemen RB.

J Am Soc Mass Spectrom. 2017 Mar;28(3):479-485. doi: 10.1007/s13361-016-1564-0. Epub 2016 Dec 13.


Role of ammonium in the ionization of phosphatidylcholines during electrospray mass spectrometry.

Rush MD, van Breemen RB.

Rapid Commun Mass Spectrom. 2017 Feb 15;31(3):264-268. doi: 10.1002/rcm.7788.


Magnetic Microbead Affinity Selection Screening (MagMASS) of Botanical Extracts for Inhibitors of 15-Lipoxygenase.

Rush MD, Walker EM, Burton T, van Breemen RB.

J Nat Prod. 2016 Nov 23;79(11):2898-2902. Epub 2016 Nov 1.


Sulfatides in extracellular vesicles isolated from plasma of multiple sclerosis patients.

Moyano AL, Li G, Boullerne AI, Feinstein DL, Hartman E, Skias D, Balavanov R, van Breemen RB, Bongarzone ER, Månsson JE, Givogri MI.

J Neurosci Res. 2016 Dec;94(12):1579-1587. doi: 10.1002/jnr.23899. Epub 2016 Aug 25.


Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS.

Li G, Nikolic D, van Breemen RB.

J Agric Food Chem. 2016 Oct 26;64(42):8062-8070. doi: 10.1021/acs.jafc.6b02954. Epub 2016 Oct 14.


Evidence supporting the conceptual framework of cancer chemoprevention in canines.

Kondratyuk TP, Adrian JA, Wright B, Park EJ, van Breemen RB, Morris KR, Pezzuto JM.

Sci Rep. 2016 May 24;6:26500. doi: 10.1038/srep26500.


Comment on "Optimal Exposure Biomarkers for Nonpersistent Chemicals in Environmental Epidemiology".

Stahlhut RW, van Breemen RB, Gerona RR, Taylor JA, Welshons WV, vom Saal FS.

Environ Health Perspect. 2016 Apr;124(4):A66. doi: 10.1289/ehp.1511057. No abstract available.


Botanical Integrity: Part 2: Traditional and Modern Analytical Approaches.

Simmler C, Chen SN, Anderson J, Lankin DC, Phansalkar R, Krause E, Dietz B, Bolton JL, Nikolic D, van Breemen RB, Pauli GF.

HerbalGram. 2016 Spring;109:60-64.


Erratum to: A round robin approach to the analysis of bisphenol a (BPA) in human blood samples.

Vandenberg LN, Gerona RR, Kannan K, Taylor JA, van Breemen RB, Dickenson CA, Liao C, Yuan Y, Newbold RR, Padmanabhan V, Vom Saal FS, Woodruff TJ.

Environ Health. 2016 Mar 8;15:43. doi: 10.1186/s12940-016-0126-z. No abstract available.


Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer.

Kataria Y, Deaton RJ, Enk E, Jin M, Petrauskaite M, Dong L, Goldenberg JR, Cotler SJ, Jensen DM, van Breemen RB, Gann PH.

BMC Gastroenterol. 2016 Feb 29;16:30. doi: 10.1186/s12876-016-0432-5.


LC-MS-MS Analysis of Brodifacoum Isomers in Rat Tissue.

Hauck ZZ, Feinstein DL, van Breemen RB.

J Anal Toxicol. 2016 May;40(4):304-9. doi: 10.1093/jat/bkw008. Epub 2016 Feb 23.


Improved Quantification of Free and Ester-Bound Gallic Acid in Foods and Beverages by UHPLC-MS/MS.

Newsome AG, Li Y, van Breemen RB.

J Agric Food Chem. 2016 Feb 17;64(6):1326-34. doi: 10.1021/acs.jafc.5b04966. Epub 2016 Feb 3.


Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa.

Imai A, Lankin DC, Nikolić D, Ahn S, van Breemen RB, Farnsworth NR, McAlpine JB, Chen SN, Pauli GF.

J Nat Prod. 2016 Mar 25;79(3):541-54. doi: 10.1021/acs.jnatprod.5b00927. Epub 2016 Jan 13.


Determination of bisphenol A-glucuronide in human urine using ultrahigh-pressure liquid chromatography/tandem mass spectrometry.

Hauck ZZ, Huang K, Li G, van Breemen RB.

Rapid Commun Mass Spectrom. 2016 Feb 15;30(3):400-6. doi: 10.1002/rcm.7450.


Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis.

Zhou Q, Chen T, Zhang W, Bozkanat M, Li Y, Xiao L, van Breemen RB, Christman JW, Sznajder JI, Zhou G.

Am J Respir Cell Mol Biol. 2016 May;54(5):728-39. doi: 10.1165/rcmb.2015-0111OC.


Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.

Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen SN, Nikolić D, Pauli GF, van Breemen RB, Dietz BM, Bolton JL.

Chem Res Toxicol. 2015 Nov 16;28(11):2130-41. doi: 10.1021/acs.chemrestox.5b00310. Epub 2015 Nov 5.


Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements.

Sprouse AA, van Breemen RB.

Drug Metab Dispos. 2016 Feb;44(2):162-71. doi: 10.1124/dmd.115.066902. Epub 2015 Oct 5. Review.


A Phase II Randomized Trial of Lycopene-Rich Tomato Extract Among Men with High-Grade Prostatic Intraepithelial Neoplasia.

Gann PH, Deaton RJ, Rueter EE, van Breemen RB, Nonn L, Macias V, Han M, Ananthanarayanan V.

Nutr Cancer. 2015;67(7):1104-12. doi: 10.1080/01635581.2015.1075560.


High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions.

Li G, Huang K, Nikolic D, van Breemen RB.

Drug Metab Dispos. 2015 Nov;43(11):1670-8. doi: 10.1124/dmd.115.065987. Epub 2015 Aug 18.


Development of Safe and Effective Botanical Dietary Supplements.

van Breemen RB.

J Med Chem. 2015 Nov 12;58(21):8360-72. doi: 10.1021/acs.jmedchem.5b00417. Epub 2015 Jul 21.


Botanical Integrity: The Importance of the Integration of Chemical, Biological, and Botanical Analyses, and the Role of DNA Barcoding.

Simmler C, Chen SN, Anderson J, Lankin DC, Phansalkar R, Krause E, Dietz B, Bolton JL, Nikolic D, van Breemen RB, Pauli GF.

HerbalGram. 2015 Summer;106:58-60.


Species-specific Standardisation of Licorice by Metabolomic Profiling of Flavanones and Chalcones.

Simmler C, Jones T, Anderson JR, Nikolić DC, van Breemen RB, Soejarto DD, Chen SN, Pauli GF.

Phytochem Anal. 2014 Jul-Aug;25(4):378-88. doi: 10.1002/pca.2472. Epub 2013 Nov 13.


Pharmacokinetic study of conventional sorafenib chemoembolization in a rabbit VX2 liver tumor model.

Parvinian A, Casadaban LC, Hauck ZZ, van Breemen RB, Gaba RC.

Diagn Interv Radiol. 2015 May-Jun;21(3):235-40. doi: 10.5152/dir.2014.14394.


Nitrogen-Containing Constituents of Black Cohosh: Chemistry, Structure Elucidation, and Biological Activities.

Nikolić D, Lankin DC, Cisowska T, Chen SN, Pauli GF, van Breemen RB.

Recent Adv Phytochem. 2015;45:31-75.


The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile.

Yu LF, Brek Eaton J, Zhang HK, Sabath E, Hanania T, Li GN, van Breemen RB, Whiteaker P, Liu Q, Wu J, Chang YC, Lukas RJ, Brunner D, Kozikowski AP.

Pharmacol Res Perspect. 2014 Apr;2(2):e00026. doi: 10.1002/prp2.26. Epub 2014 Mar 12.


Distribution of C16:0, C18:0, C24:1, and C24:0 sulfatides in central nervous system lipid rafts by quantitative ultra-high-pressure liquid chromatography tandem mass spectrometry.

Moyano AL, Li G, Lopez-Rosas A, Månsson JE, van Breemen RB, Givogri MI.

Anal Biochem. 2014 Dec 15;467:31-9. doi: 10.1016/j.ab.2014.08.033. Epub 2014 Sep 7.


Orthogonal Analysis Underscores the Relevance of Primary and Secondary Metabolites in Licorice.

Simmler C, Nikolić D, Lankin DC, Yu Y, Friesen JB, van Breemen RB, Lecomte A, Le Quémener C, Audo G, Pauli GF.

J Nat Prod. 2014 Aug 22;77(8):1806-16. doi: 10.1021/np5001945. Epub 2014 Jul 31.

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