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Items: 1 to 50 of 93

1.

Hypokalaemia in healthy volunteers after single and multiple doses of formoterol or salbutamol.

van den Berg BT, Louwerse RT, Luiken GJ, Jonkers RE, van Boxtel CJ.

Clin Drug Investig. 1998;15(6):523-9.

PMID:
18370510
2.

Steady-state pharmacokinetics of pravastatin in children with familial hypercholesterolaemia.

Wiersma HE, Wiegman A, Koopmans RP, Bakker HD, Kastelein JJ, van Boxtel CJ.

Clin Drug Investig. 2004;24(2):113-20.

PMID:
17516697
3.

Pharmacokinetics of mesalazine pellets in children with inflammatory bowel disease.

Wiersma H, Escher JC, Dilger K, Trenk D, Benninga MA, van Boxtel CJ, Taminiau J.

Inflamm Bowel Dis. 2004 Sep;10(5):626-31.

PMID:
15472525
4.
5.

Distinct actions of prednisolone and dexamethasone towards osteocalcin and eosinophilic cationic protein in assumed clinically equivalent doses: a study in healthy men.

Dubois EF, Derks MG, Zwinderman AH, Dekhuijzen PN, Van Boxtel CJ, Schweitzer DH.

Eur J Clin Pharmacol. 2003 Mar;58(11):733-7. Epub 2003 Feb 15.

PMID:
12634979
6.

Lack of relationships between cumulative methylprednisolone dose and bone mineral density in healthy men and postmenopausal women with chronic low back pain.

Dubois EF, Wagemans MF, Verdouw BC, Zwinderman AH, Van Boxtel CJ, Dekhuijzen PN, Schweitzer DH.

Clin Rheumatol. 2003 Feb;22(1):12-7.

PMID:
12605311
7.

Pharmacokinetics of a single oral dose of baclofen in pediatric patients with gastroesophageal reflux disease.

Wiersma HE, van Boxtel CJ, Butter JJ, van Aalderen WM, Omari T, Benninga MA.

Ther Drug Monit. 2003 Feb;25(1):93-8.

PMID:
12548151
8.

Beat-to-Beat Measurement of Cardiovascular Effects of a Single Subcutaneous Dose of Terbutaline in Healthy Subjects.

Mulder WMC, de Klerk S, Settels JJ, van Boxtel CJ.

Clin Drug Investig. 2002 Sep;22(9):593-600. doi: 10.2165/00044011-200222090-00004.

PMID:
29492853
9.

Effect of grapefruit juice or cimetidine coadministration on albendazole bioavailability.

Nagy J, Schipper HG, Koopmans RP, Butter JJ, Van Boxtel CJ, Kager PA.

Am J Trop Med Hyg. 2002 Mar;66(3):260-3.

PMID:
12139218
10.

Effect of dose increase or cimetidine co-administration on albendazole bioavailability.

Schipper HG, Koopmans RP, Nagy J, Butter JJ, Kager PA, Van Boxtel CJ.

Am J Trop Med Hyg. 2000 Nov-Dec;63(5-6):270-3.

PMID:
11421376
11.

Prevention by theophylline of beta-2-receptor down regulation in healthy subjects.

Derks MG, Koopmans RP, Oosterhoff E, Van Boxtel CJ.

Eur J Drug Metab Pharmacokinet. 2000 Jul-Dec;25(3-4):179-88.

PMID:
11420887
12.

The effect of grapefruit juice on the time-dependent decline of artemether plasma levels in healthy subjects.

van Agtmael MA, Gupta V, van der Graaf CA, van Boxtel CJ.

Clin Pharmacol Ther. 1999 Oct;66(4):408-14.

PMID:
10546925
13.

The development of an immunoassay for the detection of artemisinin compounds in urine.

Eggelte TA, van Agtmael MA, Vuong TD, van Boxtel CJ.

Am J Trop Med Hyg. 1999 Sep;61(3):449-56.

PMID:
10497989
14.

Grapefruit juice increases the bioavailability of artemether.

van Agtmael MA, Gupta V, van der Wösten TH, Rutten JP, van Boxtel CJ.

Eur J Clin Pharmacol. 1999 Jul;55(5):405-10.

PMID:
10456492
15.

Pharmacokinetic/pharmacodynamic modelling of the eosinopenic and hypokalemic effects of formoterol and theophylline combination in healthy men.

van den Berg BT, Derks MG, Koolen MG, Braat MC, Butter JJ, van Boxtel CJ.

Pulm Pharmacol Ther. 1999;12(3):185-92.

PMID:
10419838
16.

Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria.

van Agtmael MA, Cheng-Qi S, Qing JX, Mull R, van Boxtel CJ.

Int J Antimicrob Agents. 1999 Jul;12(2):151-8.

PMID:
10418761
17.

Artemisinin drugs in the treatment of malaria: from medicinal herb to registered medication.

van Agtmael MA, Eggelte TA, van Boxtel CJ.

Trends Pharmacol Sci. 1999 May;20(5):199-205. Review.

PMID:
10354615
18.

Simultaneous determination of fentanyl and midazolam using high-performance liquid chromatography with ultraviolet detection.

Portier EJ, de Blok K, Butter JJ, van Boxtel CJ.

J Chromatogr B Biomed Sci Appl. 1999 Feb 19;723(1-2):313-8.

PMID:
10080661
19.

The pharmacokinetics of artemisinin after administration of two different suppositories to healthy Vietnamese subjects.

Koopmans R, Ha LD, Duc DD, Dien TK, Kager PA, Khanh NX, van Boxtel CJ, De Vries PJ.

Am J Trop Med Hyg. 1999 Feb;60(2):244-7.

PMID:
10072143
20.

Declining concentrations of dihydroartemisinin in plasma during 5-day oral treatment with artesunate for Falciparum malaria.

Khanh NX, de Vries PJ, Ha LD, van Boxtel CJ, Koopmans R, Kager PA.

Antimicrob Agents Chemother. 1999 Mar;43(3):690-2.

21.

The pharmacokinetics of artemisinin suppositories in Vietnamese patients with malaria.

Koopmans R, Duc DD, Kager PA, Khanh NX, Dien TK, de Vries PJ, van Boxtel CJ.

Trans R Soc Trop Med Hyg. 1998 Jul-Aug;92(4):434-6.

PMID:
9850402
22.

The contribution of the enzymes CYP2D6 and CYP2C19 in the demethylation of artemether in healthy subjects.

van Agtmael MA, Van Der Graaf CA, Dien TK, Koopmans RP, van Boxtel CJ.

Eur J Drug Metab Pharmacokinet. 1998 Jul-Sep;23(3):429-36.

PMID:
9842988
23.

Pharmacokinetics and effects of formoterol fumarate in healthy human subjects after oral dosing.

van den Berg BT, Braat MC, van Boxtel CJ.

Eur J Clin Pharmacol. 1998 Aug;54(6):463-8.

PMID:
9776436
24.

Quinine pharmacokinetics: ototoxic and cardiotoxic effects in healthy Caucasian subjects and in patients with falciparum malaria.

Claessen FA, van Boxtel CJ, Perenboom RM, Tange RA, Wetsteijn JC, Kager PA.

Trop Med Int Health. 1998 Jun;3(6):482-9.

25.

Some observations on pharmacoepidemiology in Europe.

van Boxtel CJ, Wang G.

Neth J Med. 1997 Dec;51(6):205-12. Review.

PMID:
9499691
27.

The pharmacokinetics of a single dose of artemisinin in subjects with liver cirrhosis. Bach Mai-Amsterdam Research Group on Artemisinin.

de Vries PJ, Nguyen XK, Tran KD, Le Nguyen B, Nguyen TY, Dao DD, van Boxtel CJ, Kager PA.

Trop Med Int Health. 1997 Oct;2(10):957-62.

28.

Biphasic effect-time courses in man after formoterol inhalation: eosinopenic and hypokalemic effects and inhibition of allergic skin reactions.

Derks MG, van den Berg BT, van der Zee JS, Braat MC, van Boxtel CJ.

J Pharmacol Exp Ther. 1997 Nov;283(2):824-32.

29.

The pharmacokinetics of a single dose of artemisinin in patients with uncomplicated falciparum malaria.

De Vries PJ, Tran KD, Nguyen XK, Le Nguyen B, Pham TY, Dao DD, Van Boxtel CJ, Kager PA.

Am J Trop Med Hyg. 1997 May;56(5):503-7.

PMID:
9180598
30.

Effect of food intake on pharmacokinetics of oral artemisinin in healthy Vietnamese subjects.

Dien TK, de Vries PJ, Khanh NX, Koopmans R, Binh LN, Duc DD, Kager PA, van Boxtel CJ.

Antimicrob Agents Chemother. 1997 May;41(5):1069-72.

31.

Quinine pharmacokinetics in young children with severe malaria.

van Hensbroek MB, Kwiatkowski D, van den Berg B, Hoek FJ, van Boxtel CJ, Kager PA.

Am J Trop Med Hyg. 1996 Mar;54(3):237-42.

PMID:
8600757
32.

Pharmacokinetic-pharmacodynamic modelling as applied to bronchial asthma.

Koopmans RP, Jonkers RE, Braat MC, van Boxtel CJ.

Clin Pharmacokinet. 1995 Oct;29(4):213-20. Review. No abstract available.

PMID:
8549023
33.

The pharmacokinetics of three multiple dose regimens of chloroquine: implications for malaria chemoprophylaxis.

Wetsteyn JC, De Vries PJ, Oosterhuis B, Van Boxtel CJ.

Br J Clin Pharmacol. 1995 Jun;39(6):696-9.

34.

Evaluation of different doses of formoterol from a newly developed powder inhalation device in asthmatic patients.

van den Berg BT, Smeets JJ, van Boxtel CJ, Maesen FP.

Fundam Clin Pharmacol. 1995;9(6):593-603.

PMID:
8808181
36.

The pharmacokinetics of a single dose of artemisinin in healthy Vietnamese subjects.

Duc DD, de Vries PJ, Nguyen XK, Le Nguyen B, Kager PA, van Boxtel CJ.

Am J Trop Med Hyg. 1994 Dec;51(6):785-90.

PMID:
7810812
37.

Arteether administration in humans: preliminary studies of pharmacokinetics, safety and tolerance.

Kager PA, Schultz MJ, Zijlstra EE, van den Berg B, van Boxtel CJ.

Trans R Soc Trop Med Hyg. 1994 Jun;88 Suppl 1:S53-4.

PMID:
8053029
38.

Clinical laboratory manifestations of exposure to background levels of dioxins in the perinatal period.

Pluim HJ, Koppe JG, Olie K, van der Slikke JW, Slot PC, van Boxtel CJ.

Acta Paediatr. 1994 Jun;83(6):583-7.

PMID:
7919753
39.

First high-performance liquid chromatography assay of formoterol concentrations in the low-picogram-per-milliliter range.

van den Berg BT, Portier EJ, van den Berg M, Braat MC, van Boxtel CJ.

Ther Drug Monit. 1994 Apr;16(2):196-9.

PMID:
7912013
40.

The effect of oxprenolol dosage time on its pharmacokinetics and haemodynamic effects during exercise in man.

Koopmans R, Oosterhuis B, Karemaker JM, Wemer J, van Boxtel CJ.

Eur J Clin Pharmacol. 1993;44(2):171-6.

PMID:
8453962
41.
42.

Time-dependent effects of dexamethasone administration on the suppression of plasma hydrocortisone, assessed with a pharmacokinetic model.

Koopmans RP, Braat MC, Oosterhuis B, van Boxtel CJ.

J Pharmacol Exp Ther. 1992 Aug;262(2):503-8.

PMID:
1501110
43.

Quantification of theophylline-induced eosinopenia and hypokalaemia in healthy volunteers.

Braat MC, Jonkers RE, Bel EH, Van Boxtel CJ.

Clin Pharmacokinet. 1992 Mar;22(3):231-7.

PMID:
1559313
44.

Itraconazole compared with amphotericin B plus flucytosine in AIDS patients with cryptococcal meningitis.

de Gans J, Portegies P, Tiessens G, Eeftinck Schattenkerk JK, van Boxtel CJ, van Ketel RJ, Stam J.

AIDS. 1992 Feb;6(2):185-90.

PMID:
1313682
45.
46.

The influence of dosage time of midazolam on its pharmacokinetics and effects in humans.

Koopmans R, Dingemanse J, Danhof M, Horsten GP, van Boxtel CJ.

Clin Pharmacol Ther. 1991 Jul;50(1):16-24.

PMID:
1855349
47.

Debrisoquine phenotype and the pharmacokinetics and beta-2 receptor pharmacodynamics of metoprolol and its enantiomers.

Jonkers RE, Koopmans RP, Portier EJ, van Boxtel CJ.

J Pharmacol Exp Ther. 1991 Mar;256(3):959-66.

PMID:
1848636
48.

Pharmacodynamic modeling of lymphocytopenia and whole blood lymphocyte cultures in prednisolone-treated individuals.

Bloemena E, Koopmans RP, Weinreich S, van Boxtel CJ, Schellekens PT.

Clin Immunol Immunopathol. 1990 Dec;57(3):374-86.

PMID:
2147133
49.

Cyclosporin A levels in suction-blister fluid of patients with psoriasis treated systemically.

Meinardi MM, Van Eendenburg JP, Oosting J, Van Boxtel CJ, De Rie MA, Bos JD.

Br J Dermatol. 1990 May;122(5):671-6.

PMID:
2354118
50.

A nonsteady-state agonist antagonist interaction model using plasma potassium concentrations to quantify the beta-2 selectivity of beta blockers.

Jonkers R, van Boxtel CJ, Koopmans RP, Oosterhuis B.

J Pharmacol Exp Ther. 1989 Apr;249(1):297-302.

PMID:
2565392

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