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Items: 46

1.

8OHdG levels in brain do not indicate oxidative DNA damage in Alzheimer's disease.

Te Koppele JM, Lucassen PJ, Sakkee AN, Van Asten JG, Ravid R, Swaab DF, Van Bezooijen CF.

Neurobiol Aging. 1996 Nov-Dec;17(6):819-26.

PMID:
9363791
2.

The influence of dietary restriction on the metabolism of theophylline and antipyrine in the ageing female BN/BiRij rat.

Groen K, Breimer DD, Brouwer A, Schijff G, Jansen EJ, van Bezooijen CF.

J Pharmacol Exp Ther. 1995 Jul;274(1):143-7.

PMID:
7616391
4.

Cortisol production rate and the urinary excretion of 17-hydroxycorticosteroids, free cortisol, and 6 beta-hydroxycortisol in healthy elderly men and women.

Barton RN, Horan MA, Weijers JW, Sakkee AN, Roberts NA, van Bezooijen CF.

J Gerontol. 1993 Sep;48(5):M213-8. Erratum in: J Gerontol 1994 Jan;49(1):following B35.

PMID:
8366263
5.

The relationship between phenazone (antipyrine) metabolite formation and theophylline metabolism in healthy and frail elderly women.

Groen K, Horan MA, Roberts NA, Gulati RS, Miljkovic B, Jansen EJ, Paramsothy V, Breimer DD, van Bezooijen CF.

Clin Pharmacokinet. 1993 Aug;25(2):136-44.

PMID:
8403737
6.

Increased sensitivity to the anticonvulsant effect of valproate in aging BN/BiRij rats.

Stijnen AM, Hovinga S, Langemeijer MW, Hoogerkamp A, van Bezooijen CF, Danhof M.

Pharm Res. 1993 Jul;10(7):1046-51.

PMID:
8378246
7.
8.

Disposition of heptabarbitone in the rat: identification of a new metabolite by tandem mass spectrometry.

Stijnen AM, Heeremans CE, Van Bezooijen CF, Niessen WM, Danhof M.

J Pharm Pharmacol. 1992 Nov;44(11):907-10.

PMID:
1361535
9.

Pharmacokinetic-EEG effect relationship of midazolam in aging BN/BiRij rats.

Hovinga S, Stijnen AM, Langemeijer MW, Mandema JW, van Bezooijen CF, Danhof M.

Br J Pharmacol. 1992 Sep;107(1):171-7.

10.

Pharmacodynamics of the anticonvulsant effect of oxazepam in aging BN/BiRij rats.

Stijnen AM, Postel-Westra I, Langemeijer MW, Hoogerkamp A, Voskuyl RA, van Bezooijen CF, Danhof M.

Br J Pharmacol. 1992 Sep;107(1):165-70.

11.
12.

The effect of age on inducibility of various types of rat liver cytochrome P-450.

Horbach GJ, Van Asten JG, Rietjens IM, Kremers P, Van Bezooijen CF.

Xenobiotica. 1992 May;22(5):515-22.

PMID:
1413866
13.

Increased sensitivity to the anesthetic effect of phenobarbital in aging BN/BiRij rats.

Stijnen AM, Danhof M, Van Bezooijen CF.

J Pharmacol Exp Ther. 1992 Apr;261(1):81-7.

PMID:
1560386
14.

Effect of the aging process on the gender and phenobarbital dependent expression of glutathione S-transferase subunits in brown Norway rat liver.

Rogiers V, Coecke S, Vandenberghe Y, Morel F, Callaerts A, Verleye G, Van Bezooijen CF, Guillouzo A, Vercruysse A.

Biochem Pharmacol. 1991 Jul 15;42(3):491-8.

PMID:
1859462
15.

The influence of ageing on the induction of the mRNAs of rat liver cytochromes P450IIB1 and P450IIB2.

Horbach GJ, van Asten JG, van Bezooijen CF.

Biochem Pharmacol. 1990 Aug 1;40(3):529-33.

PMID:
2383285
16.

Hepatic cytosolic glutathione S-transferase activities in ageing brown Norway rats--importance of sex differences and phenobarbital treatment for studies of ageing.

Coecke S, Vandenberghe Y, Callaerts A, Sonck W, Verleye G, Van Bezooijen CF, Vercruysse A, Rogiers V.

Mech Ageing Dev. 1990 Aug;55(2):189-98.

PMID:
2232911
17.

Age-related changes in distribution of cytochrome P-450 in the hepatic lobule of the rat.

Machida T, Miyatake M, van Bezooijen CF.

Arch Gerontol Geriatr. 1990 Jul-Aug;11(1):43-52.

PMID:
15374492
19.

The influence of age on the inducibility of rat liver cytochrome P450IA1 (CYPIA1) and P450IA2 (CYPIA2) mRNAs.

Horbach GJ, Van Asten JG, Van Bezooijen CF.

Mutat Res. 1990 May-Jul;237(3-4):117-21.

PMID:
2233817
20.

The effect of age on the oxidative metabolism of antipyrine by uninduced microsomal fractions of rat liver.

Van Geel CA, Van Bezooijen CF.

Mech Ageing Dev. 1990 Apr 9;53(2):169-77.

PMID:
2342384
21.

Morphology, ultrastructure, and function of hepatocytes during liver drug metabolism.

van Bezooijen CF.

J Electron Microsc Tech. 1990 Feb;14(2):152-74. Review. No abstract available.

PMID:
2406389
22.

Pharmacokinetics of hexobarbital in young and old rats.

Boonstra-Nieveld IH, van Bezooijen CF.

Mech Ageing Dev. 1989 Dec;50(3):289-98.

PMID:
2630837
23.

The effect of age on antipyrine pharmacokinetics and metabolite formation in rats.

van Bezooijen CF, van Oorschot RM.

J Pharmacol Exp Ther. 1989 Nov;251(2):683-6.

PMID:
2810117
24.

The effect of age on antipyrine metabolism by liver microsomes isolated from phenobarbital-treated rats.

Henderson DJ, van Bezooijen CF.

Mech Ageing Dev. 1989 Sep;49(3):287-94.

PMID:
2811495
25.

Albumin elimination in female WAG/Rij rats with age: a longitudinal study.

Horbach GJ, Durham SK, Yap SH, van Bezooijen CF.

Mech Ageing Dev. 1988 May;43(2):137-52.

PMID:
3398603
26.
27.

Molecular aspects of age-related changes in albumin synthesis in female WAG/Rij rats.

Horbach GJ, van der Boom H, van Bezooijen CF, Yap SH.

Life Sci. 1988;43(21):1707-14.

PMID:
2461503
28.

Biomedical gerontology in the Netherlands.

van Bezooijen CF.

Tijdschr Gerontol Geriatr. 1987 May;18(2A):139-46. Review.

PMID:
3303472
29.

Anatomy, function and aging in the mouse liver.

Hollander CF, van Bezooijen CF, Solleveld HA.

Arch Toxicol Suppl. 1987;10:244-50. Review.

PMID:
3555415
30.

Changes in fluid-phase endocytosis in the rat with age and their relation to total albumin elimination.

Horbach GJ, van Leeuwen RE, Yap SH, van Bezooijen CF.

Mech Ageing Dev. 1986 Feb;33(3):305-12.

PMID:
3713267
31.

[Side effects of drugs in the elderly. A review of various possible causes].

van Bezooijen CF.

Tijdschr Gerontol Geriatr. 1985 Oct;16(5):191-8. Review. Dutch.

PMID:
3909542
32.

A decrease in the capacity of hepatocytes isolated from aged male BN/BiRij rats to metabolize digitoxin.

van Bezooijen CF, Boonstra-Nieveld IH, Sakkee AN, Knook DL.

Biochem Pharmacol. 1984 Nov 15;33(22):3709-11. No abstract available.

PMID:
6508826
33.

Changes in the sequence content of albumin mRNA and in its translational activity in the rat liver with age.

Horbach GJ, Princen HM, Van der Kroef M, Van Bezooijen CF, Yap SH.

Biochim Biophys Acta. 1984 Oct 5;783(1):60-6.

PMID:
6548156
34.
35.

Age-related changes in albumin elimination in female WAG/Rij rats.

Horbach GJ, Yap SH, van Bezooijen CF.

Biochem J. 1983 Nov 15;216(2):309-15.

36.

Meclofenoxate decreases protein and albumin synthesis in hepatocytes isolated from old rats.

van Bezooijen CF, Sakkee AN, Knook DL.

Biochem Pharmacol. 1983 Jul 15;32(14):2281-3. No abstract available.

PMID:
6409120
37.

Functional properties of rat liver protein synthesizing machinery in relation to aging.

Claes-Reckinger N, Vandenhaute J, van Bezooijen CF, Delcour J.

Exp Gerontol. 1982;17(4):281-6.

PMID:
7160446
38.

Sex and strain dependency of age-related changes in protein synthesis of isolated rat hepatocytes.

van Bezooijen CF, Sakkee AN, Knook DL.

Mech Ageing Dev. 1981 Sep;17(1):11-8.

PMID:
7311615
39.

Metabolism of digitoxin by isolated rat hepatocytes.

van Bezooijen CF, Soekawa Y, Ohta M, Nokubo M, Kitani K.

Biochem Pharmacol. 1980 Nov 1;29(21):3023-5. No abstract available.

PMID:
7458954
40.

The effect of age on protein synthesis by isolated liver parenchymal cells.

Van Bezooijen CF, Grell T, Knook DL.

Mech Ageing Dev. 1977 Jul-Aug;6(4):293-304.

PMID:
875490
41.

Respiratory activities of hepatocytes isolated from rats of various ages. A brief note.

Brouwer A, Van Bezooijen CF, Knook DL.

Mech Ageing Dev. 1977 Jul-Aug;6(4):265-9.

PMID:
875487
42.

Albumin synthesis by liver parenchymal cells isolated from young, adult and old rats.

van Bezooijen CF, Grell T, Knook DL.

Biochem Biophys Res Commun. 1976 Jul 26;71(2):513-9. No abstract available.

PMID:
822851
43.

Bromsulfophthalein uptake by isolated liver parenchymal cells.

van Bezooijen CF, Grell T, Knook DL.

Biochem Biophys Res Commun. 1976 Mar 22;69(2):354-61. No abstract available.

PMID:
1267791
44.

The viability of parenchymal liver cells isolated from young and old rats.

Van Bezooijen CF, Van Noord MJ, Knook DL.

Mech Ageing Dev. 1974 Jul-Aug;3(2):107-19. No abstract available.

PMID:
4140263
45.

On the role of hepatic cell ploidy in changes in liver function with age and following partial hepatectomy.

van Bezooijen CF, de Leeuw-Israel FR, Hollander CF.

Mech Ageing Dev. 1973 Mar;1(5):351-6. No abstract available.

PMID:
4723095
46.

Ploidy as a possible explanation for the variation in liver function during the life span of the rat.

de Leeuw-Israel FR, van Bezooijen CF, Hollander CF.

Z Alternsforsch. 1972;26(1):29-33 passim. No abstract available.

PMID:
4651460

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