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Items: 1 to 50 of 109

1.

Platelet-Dense Granules Worsen Pre-Infection Thrombocytopenia during Gram-Negative Pneumonia-Derived Sepsis.

Claushuis TAM, de Vos AF, Roelofs JJTH, de Boer OJ, van 't Veer C, van der Poll T.

J Innate Immun. 2019;11(2):168-180. doi: 10.1159/000494147. Epub 2018 Dec 17.

2.

Kinase activity is impaired in neutrophils of sepsis patients.

Hoogendijk AJ, van Vught LA, Wiewel MA, Fuhler GM, Belkasim-Bohoudi H, Horn J, Schultz MJ, Scicluna BP, Peppelenbosch MP, van 't Veer C, de Vos AF, van der Poll T.

Haematologica. 2019 Jun;104(6):e233-e235. doi: 10.3324/haematol.2018.201913. Epub 2018 Dec 4. No abstract available.

3.

Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite-induced murine asthma model.

Yang J, van 't Veer C, Roelofs JJTH, van Heijst JWJ, de Vos AF, McCrae KR, Revenko AS, Crosby J, van der Poll T.

Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L187-L196. doi: 10.1152/ajplung.00162.2018. Epub 2018 Oct 25.

PMID:
30358441
4.

Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis).

Birnie E, Claushuis TAM, Koh GCKW, Limmathurotsakul D, Day NPJ, Roelofs JJTH, Ware J, Hou B, de Vos AF, van der Poll T, van 't Veer C, Wiersinga WJ.

J Infect Dis. 2019 Jan 29;219(4):648-659. doi: 10.1093/infdis/jiy541.

5.

Inhibition of the extrinsic or intrinsic coagulation pathway during pneumonia-derived sepsis.

Stroo I, Ding C, Novak A, Yang J, Roelofs JJTH, Meijers JCM, Revenko AS, van 't Veer C, Zeerleder S, Crosby JR, van der Poll T.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L799-L809. doi: 10.1152/ajplung.00014.2018. Epub 2018 Aug 23.

PMID:
30136609
6.

Intravenous Infusion of Human Adipose Mesenchymal Stem Cells Modifies the Host Response to Lipopolysaccharide in Humans: A Randomized, Single-Blind, Parallel Group, Placebo Controlled Trial.

Perlee D, van Vught LA, Scicluna BP, Maag A, Lutter R, Kemper EM, van 't Veer C, Punchard MA, González J, Richard MP, Dalemans W, Lombardo E, de Vos AF, van der Poll T.

Stem Cells. 2018 Nov;36(11):1778-1788. doi: 10.1002/stem.2891. Epub 2018 Aug 20.

PMID:
30063804
7.

Role of Peptidylarginine Deiminase 4 in Neutrophil Extracellular Trap Formation and Host Defense during Klebsiella pneumoniae-Induced Pneumonia-Derived Sepsis.

Claushuis TAM, van der Donk LEH, Luitse AL, van Veen HA, van der Wel NN, van Vught LA, Roelofs JJTH, de Boer OJ, Lankelma JM, Boon L, de Vos AF, van 't Veer C, van der Poll T.

J Immunol. 2018 Aug 15;201(4):1241-1252. doi: 10.4049/jimmunol.1800314. Epub 2018 Jul 9.

PMID:
29987161
8.

Platelet Toll-like receptor expression and activation induced by lipopolysaccharide and sepsis.

Claushuis TAM, Van Der Veen AIP, Horn J, Schultz MJ, Houtkooper RH, Van 't Veer C, Van Der Poll T.

Platelets. 2019;30(3):296-304. doi: 10.1080/09537104.2018.1445841. Epub 2018 Mar 12.

PMID:
29528268
9.

Protease-Activated Receptor 2 Facilitates Bacterial Dissemination in Pneumococcal Pneumonia.

van den Boogaard FE, Brands X, Duitman J, de Stoppelaar SF, Borensztajn KS, Roelofs JJTH, Hollenberg MD, Spek CA, Schultz MJ, van 't Veer C, van der Poll T.

J Infect Dis. 2018 Apr 11;217(9):1462-1471. doi: 10.1093/infdis/jiy010.

PMID:
29415278
10.

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.

Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts SABM, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slütter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E.

J Am Coll Cardiol. 2018 Feb 6;71(5):527-542. doi: 10.1016/j.jacc.2017.11.055.

11.

Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria.

Claushuis TAM, de Vos AF, Nieswandt B, Boon L, Roelofs JJTH, de Boer OJ, van 't Veer C, van der Poll T.

Blood. 2018 Feb 22;131(8):864-876. doi: 10.1182/blood-2017-06-788067. Epub 2017 Nov 29.

12.

Limited role of kininogen in the host response during gram-negative pneumonia-derived sepsis.

Ding C, van 't Veer C, Roelofs JJTH, Shukla M, McCrae KR, Revenko AS, Crosby J, van der Poll T.

Am J Physiol Lung Cell Mol Physiol. 2018 Mar 1;314(3):L397-L405. doi: 10.1152/ajplung.00288.2017. Epub 2017 Nov 9.

13.

Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice.

Stroo I, Yang J, Anas AA, de Boer JD, van Mierlo G, Roem D, Wouters D, Engel R, Roelofs JJTH, van 't Veer C, van der Poll T, Zeerleder S.

PLoS One. 2017 Oct 16;12(10):e0186652. doi: 10.1371/journal.pone.0186652. eCollection 2017.

14.

Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation.

Stroo I, Zeerleder S, Ding C, Luken BM, Roelofs JJTH, de Boer OJ, Meijers JCM, Castellino FJ, van 't Veer C, van der Poll T.

Thromb Haemost. 2017 Jul 26;117(8):1601-1614. doi: 10.1160/TH16-12-0920. Epub 2017 May 11.

PMID:
28492700
15.

Sepsis Patients Display a Reduced Capacity to Activate Nuclear Factor-κB in Multiple Cell Types.

Hoogendijk AJ, Garcia-Laorden MI, van Vught LA, Wiewel MA, Belkasim-Bohoudi H, Duitman J, Horn J, Schultz MJ, Scicluna BP, van 't Veer C, de Vos AF, van der Poll T.

Crit Care Med. 2017 May;45(5):e524-e531. doi: 10.1097/CCM.0000000000002294.

PMID:
28240686
16.

Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII.

Stroo I, Yang J, de Boer JD, Roelofs JJ, van 't Veer C, Castellino FJ, Zeerleder S, van der Poll T.

Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L163-L171. doi: 10.1152/ajplung.00320.2016. Epub 2016 Dec 2.

17.

Borrelia burgdorferi Induces TLR2-Mediated Migration of Activated Dendritic Cells in an Ex Vivo Human Skin Model.

Mason LM, Wagemakers A, van 't Veer C, Oei A, van der Pot WJ, Ahmed K, van der Poll T, Geijtenbeek TB, Hovius JW.

PLoS One. 2016 Oct 3;11(10):e0164040. doi: 10.1371/journal.pone.0164040. eCollection 2016.

18.

Toll-Like Receptor Signalling Is Not Involved in Platelet Response to Streptococcus pneumoniae In Vitro or In Vivo.

de Stoppelaar SF, Claushuis TA, Schaap MC, Hou B, van der Poll T, Nieuwland R, van 't Veer C.

PLoS One. 2016 Jun 2;11(6):e0156977. doi: 10.1371/journal.pone.0156977. eCollection 2016.

19.

Impact of HIV infection on the haemostatic response during sepsis and malaria.

Huson MA, Kalkman R, Hoogendijk AJ, Alabi AS, van 't Veer C, Grobusch MP, Meijers JC, van der Poll T.

Br J Haematol. 2016 Jun;173(6):918-26. doi: 10.1111/bjh.14006. Epub 2016 Mar 11.

PMID:
26970408
20.

An Ixodes ricinus Tick Salivary Lectin Pathway Inhibitor Protects Borrelia burgdorferi sensu lato from Human Complement.

Wagemakers A, Coumou J, Schuijt TJ, Oei A, Nijhof AM, van 't Veer C, van der Poll T, Bins AD, Hovius JW.

Vector Borne Zoonotic Dis. 2016 Apr;16(4):223-8. doi: 10.1089/vbz.2015.1901. Epub 2016 Feb 22.

PMID:
26901751
21.

Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia.

Achouiti A, de Vos AF, van 't Veer C, Florquin S, Tanck MW, Nawroth PP, Bierhaus A, van der Poll T, van Zoelen MA.

PLoS One. 2016 Jan 29;11(1):e0141000. doi: 10.1371/journal.pone.0141000. eCollection 2016.

22.

Differential Toll-Like Receptor-Signalling of Burkholderia pseudomallei Lipopolysaccharide in Murine and Human Models.

Weehuizen TA, Prior JL, van der Vaart TW, Ngugi SA, Nepogodiev SA, Field RA, Kager LM, van 't Veer C, de Vos AF, Wiersinga WJ.

PLoS One. 2015 Dec 21;10(12):e0145397. doi: 10.1371/journal.pone.0145397. eCollection 2015.

23.

Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia.

Hommes TJ, van Lieshout MH, van 't Veer C, Florquin S, Bootsma HJ, Hermans PW, de Vos AF, van der Poll T.

PLoS One. 2015 Dec 16;10(12):e0145138. doi: 10.1371/journal.pone.0145138. eCollection 2015.

24.

Endoplasmic reticulum chaperone gp96 in macrophages is essential for protective immunity during Gram-negative pneumonia.

Anas AA, de Vos AF, Hoogendijk AJ, van Lieshout MH, van Heijst JW, Florquin S, Li Z, van 't Veer C, van der Poll T.

J Pathol. 2016 Jan;238(1):74-84. doi: 10.1002/path.4637. Epub 2015 Oct 19.

25.

The role of platelet MyD88 in host response during gram-negative sepsis.

de Stoppelaar SF, Claushuis TA, Jansen MP, Hou B, Roelofs JJ, van 't Veer C, van der Poll T.

J Thromb Haemost. 2015 Sep;13(9):1709-20. doi: 10.1111/jth.13048. Epub 2015 Aug 6.

26.

Feasibility and Safety of Local Treatment with Recombinant Human Tissue Factor Pathway Inhibitor in a Rat Model of Streptococcus pneumoniae Pneumonia.

van den Boogaard FE, Hofstra JJ, van 't Veer C, Levi MM, Roelofs JJ, van der Poll T, Schultz MJ.

PLoS One. 2015 May 18;10(5):e0127261. doi: 10.1371/journal.pone.0127261. eCollection 2015.

27.

Expression of inhibitory regulators of innate immunity in patients with active tuberculosis.

Blok DC, Kager LM, Hoogendijk AJ, Lede IO, Rahman W, Afroz R, Bresser P, van der Zee JS, Ghose A, Visser CE, de Jong MD, Zahed AS, Husain MA, Alam KM, Barua PC, Hassan M, Hossain A, Tayab MA, Lutter R, Day N, Dondorp AM, de Vos AF, van 't Veer C, van der Poll T.

BMC Infect Dis. 2015 Feb 26;15:98. doi: 10.1186/s12879-015-0833-z.

28.

Endogenous tissue factor pathway inhibitor has a limited effect on host defence in murine pneumococcal pneumonia.

van den Boogaard FE, van 't Veer C, Roelofs JJ, Meijers JC, Schultz MJ, Broze GJ Jr, van der Poll T.

Thromb Haemost. 2015 Jul;114(1):115-22. doi: 10.1160/TH14-12-1053. Epub 2015 Apr 2.

29.

Myeloid-related protein-14 deficiency promotes inflammation in staphylococcal pneumonia.

Achouiti A, Vogl T, Van der Meer AJ, Stroo I, Florquin S, de Boer OJ, Roth J, Zeerleder S, van 't Veer C, de Vos AF, van der Poll T.

Eur Respir J. 2015 Aug;46(2):464-73. doi: 10.1183/09031936.00183814. Epub 2015 Mar 18.

30.

The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice.

de Vos AF, Dessing MC, Lammers AJ, de Porto AP, Florquin S, de Boer OJ, de Beer R, Terpstra S, Bootsma HJ, Hermans PW, van 't Veer C, van der Poll T.

PLoS One. 2015 Feb 20;10(2):e0118181. doi: 10.1371/journal.pone.0118181. eCollection 2015.

31.

The cytoprotective effects of endogenous activated protein C reduce activation of coagulation during murine pneumococcal pneumonia and sepsis.

Schouten M, van 't Veer C, Poulussen N, Meijers JC, Levi M, Esmon CT, van der Poll T.

Thromb Res. 2015 Mar;135(3):537-43. doi: 10.1016/j.thromres.2014.12.020. Epub 2015 Jan 2.

PMID:
25586194
32.

The structure function of the death domain of human IRAK-M.

Du J, Nicolaes GA, Kruijswijk D, Versloot M, van der Poll T, van 't Veer C.

Cell Commun Signal. 2014 Dec 7;12:77. doi: 10.1186/s12964-014-0077-3.

33.

Overexpression of activated protein C hampers bacterial dissemination during pneumococcal pneumonia.

de Boer JD, Kager LM, Roelofs JJ, Meijers JC, de Boer OJ, Weiler H, Isermann B, van 't Veer C, van der Poll T.

BMC Infect Dis. 2014 Nov 4;14:559. doi: 10.1186/s12879-014-0559-3.

34.

Thrombocytopenia impairs host defense in gram-negative pneumonia-derived sepsis in mice.

de Stoppelaar SF, van 't Veer C, Claushuis TA, Albersen BJ, Roelofs JJ, van der Poll T.

Blood. 2014 Dec 11;124(25):3781-90. doi: 10.1182/blood-2014-05-573915. Epub 2014 Oct 9.

35.

Myeloid-related protein-8/14 facilitates bacterial growth during pneumococcal pneumonia.

Achouiti A, Vogl T, Endeman H, Mortensen BL, Laterre PF, Wittebole X, van Zoelen MA, Zhang Y, Hoogerwerf JJ, Florquin S, Schultz MJ, Grutters JC, Biesma DH, Roth J, Skaar EP, van 't Veer C, de Vos AF, van der Poll T.

Thorax. 2014 Nov;69(11):1034-42. doi: 10.1136/thoraxjnl-2014-205668. Epub 2014 Sep 1.

PMID:
25179663
36.

The role of platelets in sepsis.

de Stoppelaar SF, van 't Veer C, van der Poll T.

Thromb Haemost. 2014 Oct;112(4):666-77. doi: 10.1160/TH14-02-0126. Epub 2014 Jun 26. Review.

PMID:
24966015
37.

Mast cells impair host defense during murine Streptococcus pneumoniae pneumonia.

van den Boogaard FE, Brands X, Roelofs JJ, de Beer R, de Boer OJ, van 't Veer C, van der Poll T.

J Infect Dis. 2014 Nov 1;210(9):1376-84. doi: 10.1093/infdis/jiu285. Epub 2014 May 13.

PMID:
24823624
38.

A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis).

Kager LM, Wiersinga WJ, Roelofs JJ, de Boer OJ, Weiler H, van 't Veer C, van der Poll T.

PLoS Negl Trop Dis. 2014 Apr 24;8(4):e2819. doi: 10.1371/journal.pntd.0002819. eCollection 2014 Apr.

39.

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis.

van der Meer JH, van der Poll T, van 't Veer C.

Blood. 2014 Apr 17;123(16):2460-9. doi: 10.1182/blood-2013-09-528752. Epub 2014 Mar 4. Review.

40.

The endothelial protein C receptor impairs the antibacterial response in murine pneumococcal pneumonia and sepsis.

Schouten M, de Boer JD, Kager LM, Roelofs JJ, Meijers JC, Esmon CT, Levi M, van 't Veer C, van der Poll T.

Thromb Haemost. 2014 May 5;111(5):970-80. doi: 10.1160/TH13-10-0859. Epub 2014 Jan 9.

PMID:
24401906
41.

Mice lacking the lectin-like domain of thrombomodulin are protected against melioidosis.

Kager LM, Wiersinga WJ, Roelofs JJ, Stroo I, Achouiti A, van 't Veer C, Conway EM, van der Poll T.

Crit Care Med. 2014 Mar;42(3):e221-30. doi: 10.1097/CCM.0000000000000134.

PMID:
24399241
42.

High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia.

Achouiti A, van der Meer AJ, Florquin S, Yang H, Tracey KJ, van 't Veer C, de Vos AF, van der Poll T.

Crit Care. 2013 Dec 16;17(6):R296. doi: 10.1186/cc13162.

43.

Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.

de Stoppelaar SF, Bootsma HJ, Zomer A, Roelofs JJ, Hermans PW, van 't Veer C, van der Poll T.

PLoS One. 2013 Nov 11;8(11):e80062. doi: 10.1371/journal.pone.0080062. eCollection 2013.

44.

Deficiency of protease-activated receptor-1 limits bacterial dissemination during severe Gram-negative sepsis (melioidosis).

Kager LM, Wiersinga WJ, Roelofs JJ, van 't Veer C, van der Poll T.

Microbes Infect. 2014 Feb;16(2):171-4. doi: 10.1016/j.micinf.2013.11.001. Epub 2013 Nov 13.

PMID:
24239704
45.

Role of tumor necrosis factor-α in the human systemic endotoxin-induced transcriptome.

Scicluna BP, van 't Veer C, Nieuwdorp M, Felsmann K, Wlotzka B, Stroes ES, van der Poll T.

PLoS One. 2013 Nov 13;8(11):e79051. doi: 10.1371/journal.pone.0079051. eCollection 2013.

46.

Limited role of nuclear receptor Nur77 in Escherichia coli-induced peritonitis.

Hamers AA, Uleman S, van Tiel CM, Kruijswijk D, van Stalborch AM, Huveneers S, de Vries CJ, van 't Veer C.

Infect Immun. 2014 Jan;82(1):253-64. doi: 10.1128/IAI.00721-13. Epub 2013 Oct 28.

47.

Mast cell-deficient kit mice develop house dust mite-induced lung inflammation despite impaired eosinophil recruitment.

de Boer JD, Yang J, van den Boogaard FE, Hoogendijk AJ, de Beer R, van der Zee JS, Roelofs JJ, van 't Veer C, de Vos AF, van der Poll T.

J Innate Immun. 2014;6(2):219-26. doi: 10.1159/000354984. Epub 2013 Oct 18.

48.

Endogenous α2-antiplasmin is protective during severe gram-negative sepsis (melioidosis).

Kager LM, Weehuizen TA, Wiersinga WJ, Roelofs JJ, Meijers JC, Dondorp AM, van 't Veer C, van der Poll T.

Am J Respir Crit Care Med. 2013 Oct 15;188(8):967-75. doi: 10.1164/rccm.201307-1344OC.

PMID:
23992406
49.

Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis).

Kager LM, Schouten M, Wiersinga WJ, de Boer JD, Lattenist LC, Roelofs JJ, Meijers JC, Levi M, Dondorp AM, Esmon CT, van 't Veer C, van der Poll T.

PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2306. doi: 10.1371/journal.pntd.0002306. Print 2013.

50.

Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein.

Schuijt TJ, Bakhtiari K, Daffre S, Deponte K, Wielders SJ, Marquart JA, Hovius JW, van der Poll T, Fikrig E, Bunce MW, Camire RM, Nicolaes GA, Meijers JC, van 't Veer C.

Circulation. 2013 Jul 16;128(3):254-66. doi: 10.1161/CIRCULATIONAHA.113.003191. Epub 2013 Jul 1.

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