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Items: 20

1.

IgA-Mediated Killing of Tumor Cells by Neutrophils Is Enhanced by CD47-SIRPα Checkpoint Inhibition.

Treffers LW, Ten Broeke T, Rösner T, Jansen JHM, van Houdt M, Kahle S, Schornagel K, Verkuijlen PJJH, Prins JM, Franke K, Kuijpers TW, van den Berg TK, Valerius T, Leusen JHW, Matlung HL.

Cancer Immunol Res. 2020 Jan;8(1):120-130. doi: 10.1158/2326-6066.CIR-19-0144. Epub 2019 Nov 5.

PMID:
31690649
2.

Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG.

Brandsma AM, Bondza S, Evers M, Koutstaal R, Nederend M, Jansen JHM, Rösner T, Valerius T, Leusen JHW, Ten Broeke T.

Front Immunol. 2019 Apr 11;10:704. doi: 10.3389/fimmu.2019.00704. eCollection 2019.

3.

FcαRI Dynamics Are Regulated by GSK-3 and PKCζ During Cytokine Mediated Inside-Out Signaling.

Ten Broeke T, Honing H, Brandsma AM, Jacobino S, Bakema JE, Kanters D, van der Linden JAM, Bracke M, Koenderman L, Leusen JHW.

Front Immunol. 2019 Jan 31;9:3191. doi: 10.3389/fimmu.2018.03191. eCollection 2018.

4.

Mechanisms of inside-out signaling of the high-affinity IgG receptor FcγRI.

Brandsma AM, Schwartz SL, Wester MJ, Valley CC, Blezer GLA, Vidarsson G, Lidke KA, Ten Broeke T, Lidke DS, Leusen JHW.

Sci Signal. 2018 Jul 24;11(540). pii: eaaq0891. doi: 10.1126/scisignal.aaq0891.

PMID:
30042128
5.

New insights in Type I and II CD20 antibody mechanisms-of-action with a panel of novel CD20 antibodies.

Meyer S, Evers M, Jansen JHM, Buijs J, Broek B, Reitsma SE, Moerer P, Amini M, Kretschmer A, Ten Broeke T, den Hartog MT, Rijke M, Klein C, Valerius T, Boross P, Leusen JHW.

Br J Haematol. 2018 Mar;180(6):808-820. doi: 10.1111/bjh.15132. Epub 2018 Feb 22.

PMID:
29468712
6.

Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions.

Brandsma AM, Ten Broeke T, van Dueren den Hollander E, Caniels TG, Kardol-Hoefnagel T, Kuball J, Leusen JHW.

J Immunol. 2017 Oct 1;199(7):2432-2439. doi: 10.4049/jimmunol.1601929. Epub 2017 Aug 16.

7.

Effector mechanisms of IgA antibodies against CD20 include recruitment of myeloid cells for antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity.

Lohse S, Loew S, Kretschmer A, Jansen JHM, Meyer S, Ten Broeke T, Rösner T, Dechant M, Derer S, Klausz K, Kellner C, Schwanbeck R, French RR, Tipton TRW, Cragg MS, Schewe DM, Peipp M, Leusen JHW, Valerius T.

Br J Haematol. 2018 May;181(3):413-417. doi: 10.1111/bjh.14624. Epub 2017 Apr 27. No abstract available.

PMID:
28449349
8.

Fc receptor inside-out signaling and possible impact on antibody therapy.

Brandsma AM, Jacobino SR, Meyer S, ten Broeke T, Leusen JH.

Immunol Rev. 2015 Nov;268(1):74-87. doi: 10.1111/imr.12332. Review.

PMID:
26497514
9.

Simultaneous Targeting of FcγRs and FcαRI Enhances Tumor Cell Killing.

Brandsma AM, Ten Broeke T, Nederend M, Meulenbroek LA, van Tetering G, Meyer S, Jansen JH, Beltrán Buitrago MA, Nagelkerke SQ, Németh I, Ubink R, Rouwendal G, Lohse S, Valerius T, Leusen JH, Boross P.

Cancer Immunol Res. 2015 Dec;3(12):1316-24. doi: 10.1158/2326-6066.CIR-15-0099-T. Epub 2015 Sep 25.

10.

Meeting report on immunoreceptors 2014.

Ten Broeke T, van Spriel A, Sun P, Leusen J.

FASEB J. 2015 Mar;29(3):740-4. doi: 10.1096/fj.15-0302ufm. No abstract available.

PMID:
25733692
11.

MHC class II antigen presentation by dendritic cells regulated through endosomal sorting.

ten Broeke T, Wubbolts R, Stoorvogel W.

Cold Spring Harb Perspect Biol. 2013 Dec 1;5(12):a016873. doi: 10.1101/cshperspect.a016873. Review.

12.

Endosome-mediated autophagy: an unconventional MIIC-driven autophagic pathway operational in dendritic cells.

Kondylis V, van Nispen Tot Pannerden HE, van Dijk S, Ten Broeke T, Wubbolts R, Geerts WJ, Seinen C, Mutis T, Heijnen HF.

Autophagy. 2013 Jun 1;9(6):861-80. doi: 10.4161/auto.24111. Epub 2013 Mar 12.

13.

Endosomally stored MHC class II does not contribute to antigen presentation by dendritic cells at inflammatory conditions.

ten Broeke T, van Niel G, Wauben MH, Wubbolts R, Stoorvogel W.

Traffic. 2011 Aug;12(8):1025-36. doi: 10.1111/j.1600-0854.2011.01212.x. Epub 2011 May 13.

14.

Trafficking of MHC class II in dendritic cells is dependent on but not regulated by degradation of its associated invariant chain.

ten Broeke T, de Graaff A, van't Veld EM, Wauben MH, Stoorvogel W, Wubbolts R.

Traffic. 2010 Mar;11(3):324-31. doi: 10.1111/j.1600-0854.2009.01024.x. Epub 2009 Dec 3.

15.

MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways.

Buschow SI, Nolte-'t Hoen EN, van Niel G, Pols MS, ten Broeke T, Lauwen M, Ossendorp F, Melief CJ, Raposo G, Wubbolts R, Wauben MH, Stoorvogel W.

Traffic. 2009 Oct;10(10):1528-42. doi: 10.1111/j.1600-0854.2009.00963.x. Epub 2009 Jul 14.

16.

Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells.

Young LJ, Wilson NS, Schnorrer P, Proietto A, ten Broeke T, Matsuki Y, Mount AM, Belz GT, O'Keeffe M, Ohmura-Hoshino M, Ishido S, Stoorvogel W, Heath WR, Shortman K, Villadangos JA.

Nat Immunol. 2008 Nov;9(11):1244-52. doi: 10.1038/ni.1665. Epub 2008 Oct 12.

PMID:
18849989
17.

Dendritic cells regulate exposure of MHC class II at their plasma membrane by oligoubiquitination.

van Niel G, Wubbolts R, Ten Broeke T, Buschow SI, Ossendorp FA, Melief CJ, Raposo G, van Balkom BW, Stoorvogel W.

Immunity. 2006 Dec;25(6):885-94.

18.

Endocytosed transferrin receptors recycle via distinct dynamin and phosphatidylinositol 3-kinase-dependent pathways.

van Dam EM, Ten Broeke T, Jansen K, Spijkers P, Stoorvogel W.

J Biol Chem. 2002 Dec 13;277(50):48876-83. Epub 2002 Oct 7.

19.

Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2.

Alves dos Santos CM, ten Broeke T, Strous GJ.

J Biol Chem. 2001 Aug 31;276(35):32635-41. Epub 2001 Jun 19.

20.

Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

Govers R, ten Broeke T, van Kerkhof P, Schwartz AL, Strous GJ.

EMBO J. 1999 Jan 4;18(1):28-36.

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