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Items: 1 to 50 of 97

1.

In vitro-Induced Human IL-10+ B Cells Do Not Show a Subset-Defining Marker Signature and Plastically Co-express IL-10 With Pro-Inflammatory Cytokines.

Lighaam LC, Unger PA, Vredevoogd DW, Verhoeven D, Vermeulen E, Turksma AW, Ten Brinke A, Rispens T, van Ham SM.

Front Immunol. 2018 Sep 5;9:1913. doi: 10.3389/fimmu.2018.01913. eCollection 2018.

2.

Storage-Induced Platelet Apoptosis Is a Potential Risk Factor for Alloimmunization Upon Platelet Transfusion.

Saris A, Peyron I, van der Meer PF, Stuge TB, Zwaginga JJ, van Ham SM, Ten Brinke A.

Front Immunol. 2018 Jun 5;9:1251. doi: 10.3389/fimmu.2018.01251. eCollection 2018.

3.

Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ.

Hrdinová J, Verbij FC, Kaijen PHP, Hartholt RB, van Alphen F, Lardy N, Ten Brinke A, Vanhoorelbeke K, Hindocha PJ, De Groot AS, Meijer AB, Voorberg J, Peyron I.

Haematologica. 2018 Jun;103(6):1083-1092. doi: 10.3324/haematol.2017.179119. Epub 2018 Mar 22.

4.

Corrigendum: Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses.

Ten Brinke A, Marek-Trzonkowska N, Mansilla MJ, Turksma AW, Piekarska K, Iwaszkiewicz-Grześ D, Passerini L, Locafaro G, Puñet-Ortiz J, van Ham SM, Hernandez-Fuentes MP, Martínez-Cáceres EM, Gregori S.

Front Immunol. 2018 Feb 22;9:343. doi: 10.3389/fimmu.2018.00343. eCollection 2018.

5.

Repeated vaccination with tetanus toxoid of plasma donors with pre-existing specific IgE transiently elevates tetanus-specific IgE but does not induce allergic symptoms.

Unger PP, Makuch M, Aalbers M, Derksen NIL, Ten Brinke A, Aalberse RC, Rispens T, van Ham SM.

Clin Exp Allergy. 2018 Apr;48(4):479-482. doi: 10.1111/cea.13107. Epub 2018 Mar 7. No abstract available.

PMID:
29383792
6.

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, Cuturi MC, Geissler E, Giannoukakis N, Gołab K, Hafler DA, van Ham SM, Hester J, Hippen K, Di Ianni M, Ilic N, Isaacs J, Issa F, Iwaszkiewicz-Grześ D, Jaeckel E, Joosten I, Klatzmann D, Koenen H, van Kooten C, Korsgren O, Kretschmer K, Levings M, Marek-Trzonkowska NM, Martinez-Llordella M, Miljkovic D, Mills KHG, Miranda JP, Piccirillo CA, Putnam AL, Ritter T, Roncarolo MG, Sakaguchi S, Sánchez-Ramón S, Sawitzki B, Sofronic-Milosavljevic L, Sykes M, Tang Q, Vives-Pi M, Waldmann H, Witkowski P, Wood KJ, Gregori S, Hilkens CMU, Lombardi G, Lord P, Martinez-Caceres EM, Trzonkowski P.

Front Immunol. 2018 Jan 15;8:1844. doi: 10.3389/fimmu.2017.01844. eCollection 2017.

7.

Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses.

Ten Brinke A, Marek-Trzonkowska N, Mansilla MJ, Turksma AW, Piekarska K, Iwaszkiewicz-Grześ D, Passerini L, Locafaro G, Puñet-Ortiz J, van Ham SM, Hernandez-Fuentes MP, Martínez-Cáceres EM, Gregori S.

Front Immunol. 2017 Dec 21;8:1870. doi: 10.3389/fimmu.2017.01870. eCollection 2017. Erratum in: Front Immunol. 2018 Feb 22;9:343.

8.

The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages.

Verbij FC, Sorvillo N, Kaijen PHP, Hrdinova J, Peyron I, Fijnheer R, Ten Brinke A, Meijer AB, van Alphen FPJ, van den Berg TK, Graversen JJH, Moestrup SK, Voorberg J.

Blood Adv. 2017 Jan 16;1(5):293-305. doi: 10.1182/bloodadvances.2016001321. eCollection 2017 Jan 24.

9.

Platelets from donors with consistently low HLA-B8, -B12, or -B35 expression do not undergo antibody-mediated internalization.

Saris A, Tomson B, Brand A, Mulder A, Claas FH, Lorinser J, Scharenberg J, van Ham SM, Ten Brinke A, Zwaginga JJ, van der Meer PF.

Blood. 2018 Jan 4;131(1):144-152. doi: 10.1182/blood-2017-07-799270. Epub 2017 Nov 1.

PMID:
29092829
10.

Anaphylatoxin C5a Regulates 6-Sulfo-LacNAc Dendritic Cell Function in Human through Crosstalk with Toll-Like Receptor-Induced CREB Signaling.

Zaal A, Dieker M, Oudenampsen M, Turksma AW, Lissenberg-Thunnissen SN, Wouters D, van Ham SM, Ten Brinke A.

Front Immunol. 2017 Jul 14;8:818. doi: 10.3389/fimmu.2017.00818. eCollection 2017.

11.

TLR4 and C5aR crosstalk in dendritic cells induces a core regulatory network of RSK2, PI3Kβ, SGK1, and FOXO transcription factors.

Zaal A, Nota B, Moore KS, Dieker M, van Ham SM, Ten Brinke A.

J Leukoc Biol. 2017 Oct;102(4):1035-1054. doi: 10.1189/jlb.2MA0217-058R. Epub 2017 Jul 21.

PMID:
28733463
12.

To serve and protect: The modulatory role of von Willebrand factor on factor VIII immunogenicity.

Hartholt RB, van Velzen AS, Peyron I, Ten Brinke A, Fijnvandraat K, Voorberg J.

Blood Rev. 2017 Sep;31(5):339-347. doi: 10.1016/j.blre.2017.07.001. Epub 2017 Jul 4. Review.

PMID:
28716211
13.

New Anti-Eosinophil Drugs for Asthma and COPD: Targeting the Trait!

Bel EH, Ten Brinke A.

Chest. 2017 Dec;152(6):1276-1282. doi: 10.1016/j.chest.2017.05.019. Epub 2017 Jun 2. Review.

PMID:
28583618
14.

Efficacy of mepolizumab add-on therapy on health-related quality of life and markers of asthma control in severe eosinophilic asthma (MUSCA): a randomised, double-blind, placebo-controlled, parallel-group, multicentre, phase 3b trial.

Chupp GL, Bradford ES, Albers FC, Bratton DJ, Wang-Jairaj J, Nelsen LM, Trevor JL, Magnan A, Ten Brinke A.

Lancet Respir Med. 2017 May;5(5):390-400. doi: 10.1016/S2213-2600(17)30125-X. Epub 2017 Apr 5.

PMID:
28395936
15.

Enhanced uptake of blood coagulation factor VIII containing immune complexes by antigen presenting cells.

Hartholt RB, Wroblewska A, Herczenik E, Peyron I, Ten Brinke A, Rispens T, Nolte MA, Slot E, Claassens JW, Nimmerjahn F, Verbeek JS, Voorberg J.

J Thromb Haemost. 2017 Feb;15(2):329-340. doi: 10.1111/jth.13570. Epub 2017 Jan 19.

PMID:
27868337
16.

Clinical profile of patients with adult-onset eosinophilic asthma.

de Groot JC, Storm H, Amelink M, de Nijs SB, Eichhorn E, Reitsma BH, Bel EH, Ten Brinke A.

ERJ Open Res. 2016 May 26;2(2). pii: 00100-2015. eCollection 2016 Apr.

17.

Management of the patient with eosinophilic asthma: a new era begins.

de Groot JC, Ten Brinke A, Bel EH.

ERJ Open Res. 2015 Sep 23;1(1). pii: 00024-2015. eCollection 2015 May. Review. Erratum in: ERJ Open Res. 2016 Aug 25;2(3):.

18.

Clinically Relevant Reactivation of Polyomavirus BK (BKPyV) in HLA-A02-Positive Renal Transplant Recipients Is Associated with Impaired Effector-Memory Differentiation of BKPyV-Specific CD8+ T Cells.

van Aalderen MC, Remmerswaal EB, Heutinck KM, Ten Brinke A, Feltkamp MC, van der Weerd NC, van der Pant KA, Bemelman FJ, van Lier RA, Ten Berge IJ.

PLoS Pathog. 2016 Oct 10;12(10):e1005903. doi: 10.1371/journal.ppat.1005903. eCollection 2016 Oct.

19.

Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies.

Lord P, Spiering R, Aguillon JC, Anderson AE, Appel S, Benitez-Ribas D, Ten Brinke A, Broere F, Cools N, Cuturi MC, Diboll J, Geissler EK, Giannoukakis N, Gregori S, van Ham SM, Lattimer S, Marshall L, Harry RA, Hutchinson JA, Isaacs JD, Joosten I, van Kooten C, Lopez Diaz de Cerio A, Nikolic T, Oral HB, Sofronic-Milosavljevic L, Ritter T, Riquelme P, Thomson AW, Trucco M, Vives-Pi M, Martinez-Caceres EM, Hilkens CMU.

PeerJ. 2016 Aug 30;4:e2300. doi: 10.7717/peerj.2300. eCollection 2016.

20.

Predictors of frequent exacerbations in (ex)smoking and never smoking adults with severe asthma.

Westerhof GA, de Groot JC, Amelink M, de Nijs SB, Ten Brinke A, Weersink EJ, Bel EH.

Respir Med. 2016 Sep;118:122-127. doi: 10.1016/j.rmed.2016.08.006. Epub 2016 Aug 9.

21.

A 1-day visit in a severe asthma centre: effect on asthma control, quality of life and healthcare use.

van der Meer AN, Pasma H, Kempenaar-Okkema W, Pelinck JA, Schutten M, Storm H, Ten Brinke A.

Eur Respir J. 2016 Sep;48(3):726-33. doi: 10.1183/13993003.00220-2016. Epub 2016 Jun 23.

22.

Adaptation to replating of dendritic cells synergizes with Toll-like receptor stimuli and enhances the pro-inflammatory cytokine profile.

Kolanowski ST, van Schijndel GM, van Ham SM, Ten Brinke A.

Cytotherapy. 2016 Jul;18(7):902-10. doi: 10.1016/j.jcyt.2016.03.298. Epub 2016 May 18.

PMID:
27209277
23.

Monophosphoryl lipid A-induced pro-inflammatory cytokine expression does not require CD14 in primary human dendritic cells.

Kolanowski ST, Lissenberg-Thunnissen SN, Emal D, van Ham SM, Ten Brinke A.

Inflamm Res. 2016 Jun;65(6):449-58. doi: 10.1007/s00011-016-0927-0. Epub 2016 Mar 18.

PMID:
26994069
24.

Clinical Use of Tolerogenic Dendritic Cells-Harmonization Approach in European Collaborative Effort.

Ten Brinke A, Hilkens CM, Cools N, Geissler EK, Hutchinson JA, Lombardi G, Lord P, Sawitzki B, Trzonkowski P, Van Ham SM, Martinez-Caceres EM.

Mediators Inflamm. 2015;2015:471719. doi: 10.1155/2015/471719. Epub 2015 Dec 24. Review.

25.

CD4+ T cells from patients with acquired thrombotic thrombocytopenic purpura recognize CUB2 domain-derived peptides.

Verbij FC, Turksma AW, de Heij F, Kaijen P, Lardy N, Fijnheer R, Sorvillo N, ten Brinke A, Voorberg J.

Blood. 2016 Mar 24;127(12):1606-9. doi: 10.1182/blood-2015-10-668053. Epub 2016 Jan 8.

26.

IL-10/IFNγ co-expressing CD4(+) T cells induced by IL-10 DC display a regulatory gene profile and downmodulate T cell responses.

Boks MA, Kager-Groenland JR, van Ham SM, ten Brinke A.

Clin Immunol. 2016 Jan;162:91-9. doi: 10.1016/j.clim.2015.11.011. Epub 2015 Nov 27.

PMID:
26639194
27.

von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.

Sorvillo N, Hartholt RB, Bloem E, Sedek M, ten Brinke A, van der Zwaan C, van Alphen FP, Meijer AB, Voorberg J.

Haematologica. 2016 Mar;101(3):309-18. doi: 10.3324/haematol.2015.137067. Epub 2015 Dec 3.

28.

Risk factors for frequent severe exacerbations in late-onset eosinophilic asthma.

de Groot JC, Amelink M, de Nijs SB, Plaat R, Reitsma BH, Storm H, Bel EH, Ten Brinke A.

Am J Respir Crit Care Med. 2015 Oct 1;192(7):899-902. doi: 10.1164/rccm.201505-1003LE. No abstract available.

PMID:
26426787
29.

Hurdles in therapy with regulatory T cells.

Trzonkowski P, Bacchetta R, Battaglia M, Berglund D, Bohnenkamp HR, ten Brinke A, Bushell A, Cools N, Geissler EK, Gregori S, Marieke van Ham S, Hilkens C, Hutchinson JA, Lombardi G, Madrigal JA, Marek-Trzonkowska N, Martinez-Caceres EM, Roncarolo MG, Sanchez-Ramon S, Saudemont A, Sawitzki B.

Sci Transl Med. 2015 Sep 9;7(304):304ps18. doi: 10.1126/scitranslmed.aaa7721. Review.

PMID:
26355029
30.

Biomarkers to identify sputum eosinophilia in different adult asthma phenotypes.

Westerhof GA, Korevaar DA, Amelink M, de Nijs SB, de Groot JC, Wang J, Weersink EJ, ten Brinke A, Bossuyt PM, Bel EH.

Eur Respir J. 2015 Sep;46(3):688-96. doi: 10.1183/09031936.00012415. Epub 2015 Jun 25.

31.

Reply: To PMID 25617224.

de Groot JC, ten Brinke A, Bel EH.

J Allergy Clin Immunol. 2015 Aug;136(2):516. doi: 10.1016/j.jaci.2015.04.035. Epub 2015 Jun 9. No abstract available.

PMID:
26070881
32.

Reply: To PMID 25617224.

de Groot JC, ten Brinke A, Bel EH.

J Allergy Clin Immunol. 2015 Aug;136(2):517-8. doi: 10.1016/j.jaci.2015.04.036. Epub 2015 Jun 9. No abstract available.

PMID:
26070880
33.

Infection history determines the differentiation state of human CD8+ T cells.

van Aalderen MC, Remmerswaal EB, Verstegen NJ, Hombrink P, ten Brinke A, Pircher H, Kootstra NA, ten Berge IJ, van Lier RA.

J Virol. 2015 May;89(9):5110-23. doi: 10.1128/JVI.03478-14. Epub 2015 Feb 25.

34.

Vitamin D reduces eosinophilic airway inflammation in nonatopic asthma.

de Groot JC, van Roon EN, Storm H, Veeger NJ, Zwinderman AH, Hiemstra PS, Bel EH, ten Brinke A.

J Allergy Clin Immunol. 2015 Mar;135(3):670-5.e3. doi: 10.1016/j.jaci.2014.11.033. Epub 2015 Jan 21.

PMID:
25617224
35.

A central role for Notch in effector CD8(+) T cell differentiation.

Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF, ten Brinke A, Willemsen AM, van Kampen AH, Kaech SM, Blander JM, van Gisbergen K, Amsen D.

Nat Immunol. 2014 Dec;15(12):1143-51. doi: 10.1038/ni.3027. Epub 2014 Oct 26.

36.

Clonal evolution of CD8+ T cell responses against latent viruses: relationship among phenotype, localization, and function.

Remmerswaal EB, Klarenbeek PL, Alves NL, Doorenspleet ME, van Schaik BD, Esveldt RE, Idu MM, van Leeuwen EM, van der Bom-Baylon N, van Kampen AH, Koch SD, Pircher H, Bemelman FJ, Ten Brinke A, Baas F, Ten Berge IJ, van Lier RA, de Vries N.

J Virol. 2015 Jan;89(1):568-80. doi: 10.1128/JVI.02003-14. Epub 2014 Oct 22.

37.

Redefining Strategies to Introduce Tolerance-Inducing Cellular Therapy in Human beings to Combat Autoimmunity and Transplantation Reactions.

Ten Brinke A, Joosten I, van Ham SM, van Kooten C, Prakken BJ.

Front Immunol. 2014 Aug 15;5:392. doi: 10.3389/fimmu.2014.00392. eCollection 2014. Review.

38.

Inhibition of TNF receptor signaling by anti-TNFα biologicals primes naïve CD4(+) T cells towards IL-10(+) T cells with a regulatory phenotype and function.

Boks MA, Kager-Groenland JR, Mousset CM, van Ham SM, ten Brinke A.

Clin Immunol. 2014 Apr;151(2):136-45. doi: 10.1016/j.clim.2014.02.008. Epub 2014 Feb 22.

PMID:
24568737
39.

Comparison of media and serum supplementation for generation of monophosphoryl lipid A/interferon-γ-matured type I dendritic cells for immunotherapy.

Kolanowski ST, Sritharan L, Lissenberg-Thunnissen SN, Van Schijndel GM, Van Ham SM, ten Brinke A.

Cytotherapy. 2014 Jun;16(6):826-34. doi: 10.1016/j.jcyt.2013.12.005. Epub 2014 Feb 12.

PMID:
24529557
40.

Anxiety, depression and personality traits in severe, prednisone-dependent asthma.

Amelink M, Hashimoto S, Spinhoven P, Pasma HR, Sterk PJ, Bel EH, ten Brinke A.

Respir Med. 2014 Mar;108(3):438-44. doi: 10.1016/j.rmed.2013.12.012. Epub 2014 Jan 2.

41.

Frequent exacerbators--a distinct phenotype of severe asthma.

Kupczyk M, ten Brinke A, Sterk PJ, Bel EH, Papi A, Chanez P, Nizankowska-Mogilnicka E, Gjomarkaj M, Gaga M, Brusselle G, Dahlén B, Dahlén SE; BIOAIR investigators.

Clin Exp Allergy. 2014 Feb;44(2):212-21. doi: 10.1111/cea.12179.

PMID:
24447083
42.

Limited promiscuity of HLA-DRB1 presented peptides derived of blood coagulation factor VIII.

van Haren SD, Wroblewska A, Herczenik E, Kaijen PH, Ruminska A, ten Brinke A, Meijer AB, Voorberg J.

PLoS One. 2013 Nov 14;8(11):e80239. doi: 10.1371/journal.pone.0080239. eCollection 2013.

43.

TLR4-mediated pro-inflammatory dendritic cell differentiation in humans requires the combined action of MyD88 and TRIF.

Kolanowski ST, Dieker MC, Lissenberg-Thunnissen SN, van Schijndel GM, van Ham SM, ten Brinke A.

Innate Immun. 2014 May;20(4):423-30. doi: 10.1177/1753425913498626. Epub 2013 Aug 13.

PMID:
23941760
44.

Phenotypic and functional characterization of circulating polyomavirus BK VP1-specific CD8+ T cells in healthy adults.

van Aalderen MC, Remmerswaal EB, Heutinck KM, ten Brinke A, Pircher H, van Lier RA, ten Berge IJ.

J Virol. 2013 Sep;87(18):10263-72. doi: 10.1128/JVI.01540-13. Epub 2013 Jul 17.

45.

Severe adult-onset asthma: A distinct phenotype.

Amelink M, de Groot JC, de Nijs SB, Lutter R, Zwinderman AH, Sterk PJ, ten Brinke A, Bel EH.

J Allergy Clin Immunol. 2013 Aug;132(2):336-41. doi: 10.1016/j.jaci.2013.04.052. Epub 2013 Jun 24.

PMID:
23806634
46.

NKG2D induces Mcl-1 expression and mediates survival of CD8 memory T cell precursors via phosphatidylinositol 3-kinase.

Wensveen FM, Lenartic M, Jelencic V, Lemmermann NA, ten Brinke A, Jonjic S, Polic B.

J Immunol. 2013 Aug 1;191(3):1307-15. doi: 10.4049/jimmunol.1300670. Epub 2013 Jun 26.

47.

Three phenotypes of adult-onset asthma.

Amelink M, de Nijs SB, de Groot JC, van Tilburg PM, van Spiegel PI, Krouwels FH, Lutter R, Zwinderman AH, Weersink EJ, ten Brinke A, Sterk PJ, Bel EH.

Allergy. 2013;68(5):674-80. doi: 10.1111/all.12136.

PMID:
23590217
48.

Preferential HLA-DRB1*11-dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells.

Sorvillo N, van Haren SD, Kaijen PH, ten Brinke A, Fijnheer R, Meijer AB, Voorberg J.

Blood. 2013 Apr 25;121(17):3502-10. doi: 10.1182/blood-2012-09-456780. Epub 2013 Jan 31.

49.

Pro-apoptotic protein Noxa regulates memory T cell population size and protects against lethal immunopathology.

Wensveen FM, Klarenbeek PL, van Gisbergen KP, Pascutti MF, Derks IA, van Schaik BD, Ten Brinke A, de Vries N, Cekinovic D, Jonjic S, van Lier RA, Eldering E.

J Immunol. 2013 Feb 1;190(3):1180-91. doi: 10.4049/jimmunol.1202304. Epub 2012 Dec 31.

50.

Risk of deep vein thrombosis and pulmonary embolism in asthma.

Majoor CJ, Kamphuisen PW, Zwinderman AH, Ten Brinke A, Amelink M, Rijssenbeek-Nouwens L, Sterk PJ, Büller HR, Bel EH.

Eur Respir J. 2013 Sep;42(3):655-61. doi: 10.1183/09031936.00150312. Epub 2012 Dec 20.

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