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Items: 35


Flu transcription captured in action.

Te Velthuis AJW.

Nat Struct Mol Biol. 2019 Jun;26(6):393-395. doi: 10.1038/s41594-019-0243-9. No abstract available.


Single-Cell Virus Sequencing of Influenza Infections That Trigger Innate Immunity.

Russell AB, Elshina E, Kowalsky JR, Te Velthuis AJW, Bloom JD.

J Virol. 2019 Jun 28;93(14). pii: e00500-19. doi: 10.1128/JVI.00500-19. Print 2019 Jul 15.


Real-time analysis of single influenza virus replication complexes reveals large promoter-dependent differences in initiation dynamics.

Robb NC, Te Velthuis AJW, Fodor E, Kapanidis AN.

Nucleic Acids Res. 2019 Jul 9;47(12):6466-6477. doi: 10.1093/nar/gkz313.


The mechanism of resistance to favipiravir in influenza.

Goldhill DH, Te Velthuis AJW, Fletcher RA, Langat P, Zambon M, Lackenby A, Barclay WS.

Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11613-11618. doi: 10.1073/pnas.1811345115. Epub 2018 Oct 23.


Mini viral RNAs act as innate immune agonists during influenza virus infection.

Te Velthuis AJW, Long JC, Bauer DLV, Fan RLY, Yen HL, Sharps J, Siegers JY, Killip MJ, French H, Oliva-Martín MJ, Randall RE, de Wit E, van Riel D, Poon LLM, Fodor E.

Nat Microbiol. 2018 Nov;3(11):1234-1242. doi: 10.1038/s41564-018-0240-5. Epub 2018 Sep 17.


Assays to Measure the Activity of Influenza Virus Polymerase.

Te Velthuis AJW, Long JS, Barclay WS.

Methods Mol Biol. 2018;1836:343-374. doi: 10.1007/978-1-4939-8678-1_17.


Initiation, Elongation, and Realignment during Influenza Virus mRNA Synthesis.

Te Velthuis AJW, Oymans J.

J Virol. 2018 Jan 17;92(3). pii: e01775-17. doi: 10.1128/JVI.01775-17. Print 2018 Feb 1.


A Mechanism for Priming and Realignment during Influenza A Virus Replication.

Oymans J, Te Velthuis AJW.

J Virol. 2018 Jan 17;92(3). pii: e01773-17. doi: 10.1128/JVI.01773-17. Print 2018 Feb 1.


Erratum for Nilsson et al., "Role of the PB2 627 Domain in Influenza A Virus Polymerase Function".

Nilsson BE, Te Velthuis AJW, Fodor E.

J Virol. 2017 May 26;91(12). pii: e00523-17. doi: 10.1128/JVI.00523-17. Print 2017 Jun 15. No abstract available.


Nidovirus RNA polymerases: Complex enzymes handling exceptional RNA genomes.

Posthuma CC, Te Velthuis AJW, Snijder EJ.

Virus Res. 2017 Apr 15;234:58-73. doi: 10.1016/j.virusres.2017.01.023. Epub 2017 Feb 6. Review.


Role of the PB2 627 Domain in Influenza A Virus Polymerase Function.

Nilsson BE, Te Velthuis AJW, Fodor E.

J Virol. 2017 Mar 13;91(7). pii: e02467-16. doi: 10.1128/JVI.02467-16. Print 2017 Apr 1. Erratum in: J Virol. 2017 May 26;91(12 ):.


Single-molecule FRET reveals the pre-initiation and initiation conformations of influenza virus promoter RNA.

Robb NC, Te Velthuis AJ, Wieneke R, Tampé R, Cordes T, Fodor E, Kapanidis AN.

Nucleic Acids Res. 2016 Dec 1;44(21):10304-10315. Epub 2016 Sep 30.


The role of the priming loop in influenza A virus RNA synthesis.

Te Velthuis AJ, Robb NC, Kapanidis AN, Fodor E.

Nat Microbiol. 2016 Mar 21;1:16029. doi: 10.1038/nmicrobiol.2016.29.


Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis.

Te Velthuis AJ, Fodor E.

Nat Rev Microbiol. 2016 Aug;14(8):479-93. doi: 10.1038/nrmicro.2016.87. Epub 2016 Jul 11. Review.


The role of the priming loop in Influenza A virus RNA synthesis.

Te Velthuis AJ, Robb NC, Kapanidis AN, Fodor E.

Nat Microbiol. 2016 May;1(5). pii: 16029. Epub 2016 Mar 21.


The RNA-dependent RNA polymerase of the influenza A virus.

Stubbs TM, Te Velthuis AJ.

Future Virol. 2014 Sep;9(9):863-876.


Common and unique features of viral RNA-dependent polymerases.

te Velthuis AJ.

Cell Mol Life Sci. 2014 Nov;71(22):4403-20. doi: 10.1007/s00018-014-1695-z. Epub 2014 Aug 1. Review.


Host restriction of influenza virus polymerase activity by PB2 627E is diminished on short viral templates in a nucleoprotein-independent manner.

Paterson D, te Velthuis AJ, Vreede FT, Fodor E.

J Virol. 2014 Jan;88(1):339-44. doi: 10.1128/JVI.02022-13. Epub 2013 Oct 23.


Uncoupling of influenza A virus transcription and replication through mutation of the unpaired adenosine in the viral RNA promoter.

te Velthuis AJ, Turrell L, Vreede FT, Fodor E.

J Virol. 2013 Sep;87(18):10381-4. doi: 10.1128/JVI.00636-13. Epub 2013 Jul 17.


Mechanism of nucleic acid unwinding by SARS-CoV helicase.

Adedeji AO, Marchand B, Te Velthuis AJ, Snijder EJ, Weiss S, Eoff RL, Singh K, Sarafianos SG.

PLoS One. 2012;7(5):e36521. doi: 10.1371/journal.pone.0036521. Epub 2012 May 15.


The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension.

te Velthuis AJ, van den Worm SH, Snijder EJ.

Nucleic Acids Res. 2012 Feb;40(4):1737-47. doi: 10.1093/nar/gkr893. Epub 2011 Oct 29.


The nature of protein domain evolution: shaping the interaction network.

Bagowski CP, Bruins W, Te Velthuis AJ.

Curr Genomics. 2010 Aug;11(5):368-76. doi: 10.2174/138920210791616725.


Genome-wide analysis of PDZ domain binding reveals inherent functional overlap within the PDZ interaction network.

te Velthuis AJ, Sakalis PA, Fowler DA, Bagowski CP.

PLoS One. 2011 Jan 24;6(1):e16047. doi: 10.1371/journal.pone.0016047.


Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture.

te Velthuis AJ, van den Worm SH, Sims AC, Baric RS, Snijder EJ, van Hemert MJ.

PLoS Pathog. 2010 Nov 4;6(11):e1001176. doi: 10.1371/journal.ppat.1001176.


Quantitative guidelines for force calibration through spectral analysis of magnetic tweezers data.

te Velthuis AJ, Kerssemakers JW, Lipfert J, Dekker NH.

Biophys J. 2010 Aug 9;99(4):1292-302. doi: 10.1016/j.bpj.2010.06.008.


Integrity of the early secretory pathway promotes, but is not required for, severe acute respiratory syndrome coronavirus RNA synthesis and virus-induced remodeling of endoplasmic reticulum membranes.

Knoops K, Swett-Tapia C, van den Worm SH, Te Velthuis AJ, Koster AJ, Mommaas AM, Snijder EJ, Kikkert M.

J Virol. 2010 Jan;84(2):833-46. doi: 10.1128/JVI.01826-09. Epub 2009 Nov 4.


The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent.

te Velthuis AJ, Arnold JJ, Cameron CE, van den Worm SH, Snijder EJ.

Nucleic Acids Res. 2010 Jan;38(1):203-14. doi: 10.1093/nar/gkp904. Epub 2009 Oct 29. Erratum in: Nucleic Acids Res. 2011 Nov;39(21):9458.


Linking fold, function and phylogeny: a comparative genomics view on protein (domain) evolution.

Te Velthuis AJ, Bagowski CP.

Curr Genomics. 2008 Apr;9(2):88-96. doi: 10.2174/138920208784139537.


The lim domain only protein 7 is important in zebrafish heart development.

Ott EB, van den Akker NM, Sakalis PA, Gittenberger-de Groot AC, Te Velthuis AJ, Bagowski CP.

Dev Dyn. 2008 Dec;237(12):3940-52. doi: 10.1002/dvdy.21807.


PDZ and LIM domain-encoding genes: molecular interactions and their role in development.

te Velthuis AJ, Bagowski CP.

ScientificWorldJournal. 2007 Sep 1;7:1470-92. Review.


Molecular evolution of the MAGUK family in metazoan genomes.

te Velthuis AJ, Admiraal JF, Bagowski CP.

BMC Evol Biol. 2007 Aug 2;7:129.


The nested open reading frame in the Epstein-Barr virus nuclear antigen-1 mRNA encodes a protein capable of inhibiting antigen presentation in cis.

Ossevoort M, Zaldumbide A, te Velthuis AJ, Melchers M, Ressing ME, Wiertz EJ, Hoeben RC.

Mol Immunol. 2007 Jul;44(14):3588-96. Epub 2007 Apr 20.


Comparative analysis of splice form-specific expression of LIM Kinases during zebrafish development.

Ott EB, Te Velthuis AJ, Bagowski CP.

Gene Expr Patterns. 2007 Apr;7(5):620-9. Epub 2006 Dec 29.


Gene expression patterns of the ALP family during zebrafish development.

te Velthuis AJ, Ott EB, Marques IJ, Bagowski CP.

Gene Expr Patterns. 2007 Jan;7(3):297-305. Epub 2006 Sep 7.


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