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Items: 18


Vps34 and the Armus/TBC-2 Rab GAPs: Putting the brakes on the endosomal Rab5 and Rab7 GTPases.

Law F, Rocheleau CE.

Cell Logist. 2017 Dec 19;7(4):e1403530. doi: 10.1080/21592799.2017.1403530. eCollection 2017. Review.


C. elegans Vulva Induction: An In Vivo Model to Study Epidermal Growth Factor Receptor Signaling and Trafficking.

Gauthier K, Rocheleau CE.

Methods Mol Biol. 2017;1652:43-61. doi: 10.1007/978-1-4939-7219-7_3. Review.


The VPS34 PI3K negatively regulates RAB-5 during endosome maturation.

Law F, Seo JH, Wang Z, DeLeon JL, Bolis Y, Brown A, Zong WX, Du G, Rocheleau CE.

J Cell Sci. 2017 Jun 15;130(12):2007-2017. doi: 10.1242/jcs.194746. Epub 2017 Apr 28.


Dynein-mediated trafficking negatively regulates LET-23 EGFR signaling.

Skorobogata O, Meng J, Gauthier K, Rocheleau CE.

Mol Biol Cell. 2016 Sep 21. pii: mbc.E15-11-0757. [Epub ahead of print]


An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signaling during C. elegans vulva induction.

Skorobogata O, Escobar-Restrepo JM, Rocheleau CE.

PLoS Genet. 2014 Oct 16;10(10):e1004728. doi: 10.1371/journal.pgen.1004728. eCollection 2014 Oct.


RNA interference: Systemic RNAi SIDes with endosomes.

Rocheleau CE.

Curr Biol. 2012 Oct 23;22(20):R873-5. doi: 10.1016/j.cub.2012.08.039.


CED-10/Rac1 regulates endocytic recycling through the RAB-5 GAP TBC-2.

Sun L, Liu O, Desai J, Karbassi F, Sylvain MA, Shi A, Zhou Z, Rocheleau CE, Grant BD.

PLoS Genet. 2012;8(7):e1002785. doi: 10.1371/journal.pgen.1002785. Epub 2012 Jul 12.


RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans.

Skorobogata O, Rocheleau CE.

PLoS One. 2012;7(4):e36489. doi: 10.1371/journal.pone.0036489. Epub 2012 Apr 30.


TBC-2 is required for embryonic yolk protein storage and larval survival during L1 diapause in Caenorhabditis elegans.

Chotard L, Skorobogata O, Sylvain MA, Shrivastava S, Rocheleau CE.

PLoS One. 2010 Dec 28;5(12):e15662. doi: 10.1371/journal.pone.0015662.


TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans.

Chotard L, Mishra AK, Sylvain MA, Tuck S, Lambright DG, Rocheleau CE.

Mol Biol Cell. 2010 Jul 1;21(13):2285-96. doi: 10.1091/mbc.E09-11-0947. Epub 2010 May 12.


The Caenorhabditis elegans ekl (enhancer of ksr-1 lethality) genes include putative components of a germline small RNA pathway.

Rocheleau CE, Cullison K, Huang K, Bernstein Y, Spilker AC, Sundaram MV.

Genetics. 2008 Mar;178(3):1431-43. doi: 10.1534/genetics.107.084608. Epub 2008 Feb 3.


Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling.

Rocheleau CE, Rönnlund A, Tuck S, Sundaram MV.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11757-62. Epub 2005 Aug 5.


SRC-1 and Wnt signaling act together to specify endoderm and to control cleavage orientation in early C. elegans embryos.

Bei Y, Hogan J, Berkowitz LA, Soto M, Rocheleau CE, Pang KM, Collins J, Mello CC.

Dev Cell. 2002 Jul;3(1):113-25.


A lin-45 raf enhancer screen identifies eor-1, eor-2 and unusual alleles of Ras pathway genes in Caenorhabditis elegans.

Rocheleau CE, Howard RM, Goldman AP, Volk ML, Girard LJ, Sundaram MV.

Genetics. 2002 May;161(1):121-31.


C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation.

Ohmachi M, Rocheleau CE, Church D, Lambie E, Schedl T, Sundaram MV.

Curr Biol. 2002 Mar 5;12(5):427-33.


MOM-4, a MAP kinase kinase kinase-related protein, activates WRM-1/LIT-1 kinase to transduce anterior/posterior polarity signals in C. elegans.

Shin TH, Yasuda J, Rocheleau CE, Lin R, Soto M, Bei Y, Davis RJ, Mello CC.

Mol Cell. 1999 Aug;4(2):275-80.


WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans.

Rocheleau CE, Yasuda J, Shin TH, Lin R, Sawa H, Okano H, Priess JR, Davis RJ, Mello CC.

Cell. 1999 Jun 11;97(6):717-26.


Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos.

Rocheleau CE, Downs WD, Lin R, Wittmann C, Bei Y, Cha YH, Ali M, Priess JR, Mello CC.

Cell. 1997 Aug 22;90(4):707-16.

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