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Items: 1 to 20 of 202

1.

The road to long-term survival: Surgical approach and longitudinal treatments of long-term survivors of advanced-stage serous ovarian cancer.

Javellana M, Hoppenot C, Lengyel E.

Gynecol Oncol. 2018 Nov 21. pii: S0090-8258(18)31404-5. doi: 10.1016/j.ygyno.2018.11.007. [Epub ahead of print]

PMID:
30471899
2.

A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns.

Loessner D, Rockstroh A, Shokoohmand A, Holzapfel BM, Wagner F, Baldwin J, Boxberg M, Schmalfeldt B, Lengyel E, Clements JA, Hutmacher DW.

Biomaterials. 2018 Oct 16;190-191:63-75. doi: 10.1016/j.biomaterials.2018.10.014. [Epub ahead of print]

PMID:
30396040
3.

Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer.

Coscia F, Lengyel E, Duraiswamy J, Ashcroft B, Bassani-Sternberg M, Wierer M, Johnson A, Wroblewski K, Montag A, Yamada SD, López-Méndez B, Nilsson J, Mund A, Mann M, Curtis M.

Cell. 2018 Sep 20;175(1):159-170.e16. doi: 10.1016/j.cell.2018.08.065.

PMID:
30241606
4.

Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis.

Curtis M, Kenny HA, Ashcroft B, Mukherjee A, Johnson A, Zhang Y, Helou Y, Batlle R, Liu X, Gutierrez N, Gao X, Yamada SD, Lastra R, Montag A, Ahsan N, Locasale JW, Salomon AR, Nebreda AR, Lengyel E.

Cell Metab. 2018 Aug 28. pii: S1550-4131(18)30508-4. doi: 10.1016/j.cmet.2018.08.007. [Epub ahead of print]

PMID:
30174305
5.

m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.

Liu J, Eckert MA, Harada BT, Liu SM, Lu Z, Yu K, Tienda SM, Chryplewicz A, Zhu AC, Yang Y, Huang JT, Chen SM, Xu ZG, Leng XH, Yu XC, Cao J, Zhang Z, Liu J, Lengyel E, He C.

Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.

PMID:
30154548
6.

The Tumor Microenvironment Takes Center Stage in Ovarian Cancer Metastasis.

Curtis M, Mukherjee A, Lengyel E.

Trends Cancer. 2018 Aug;4(8):517-519. doi: 10.1016/j.trecan.2018.06.002. Epub 2018 Jun 22.

PMID:
30064659
7.

Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor-Engineered T Cells for Ovarian Cancer.

Matsuda T, Leisegang M, Park JH, Ren L, Kato T, Ikeda Y, Harada M, Kiyotani K, Lengyel E, Fleming GF, Nakamura Y.

Clin Cancer Res. 2018 Nov 1;24(21):5357-5367. doi: 10.1158/1078-0432.CCR-18-0142. Epub 2018 May 2.

PMID:
29720506
8.

Cancer as a Matter of Fat: The Crosstalk between Adipose Tissue and Tumors.

Lengyel E, Makowski L, DiGiovanni J, Kolonin MG.

Trends Cancer. 2018 May;4(5):374-384. doi: 10.1016/j.trecan.2018.03.004. Epub 2018 Apr 5. Review.

PMID:
29709261
9.

Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis.

Ladanyi A, Mukherjee A, Kenny HA, Johnson A, Mitra AK, Sundaresan S, Nieman KM, Pascual G, Benitah SA, Montag A, Yamada SD, Abumrad NA, Lengyel E.

Oncogene. 2018 Apr;37(17):2285-2301. doi: 10.1038/s41388-017-0093-z. Epub 2018 Feb 5.

10.

An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells.

Li G, Montgomery JE, Eckert MA, Chang JW, Tienda SM, Lengyel E, Moellering RE.

Nat Commun. 2017 Nov 24;8(1):1775. doi: 10.1038/s41467-017-01854-0.

11.

Who are the long-term survivors of high grade serous ovarian cancer?

Hoppenot C, Eckert MA, Tienda SM, Lengyel E.

Gynecol Oncol. 2018 Jan;148(1):204-212. doi: 10.1016/j.ygyno.2017.10.032. Epub 2017 Nov 8. Review.

PMID:
29128106
12.

High glucocorticoid receptor expression predicts short progression-free survival in ovarian cancer.

Veneris JT, Darcy KM, Mhawech-Fauceglia P, Tian C, Lengyel E, Lastra RR, Pejovic T, Conzen SD, Fleming GF.

Gynecol Oncol. 2017 Jul;146(1):153-160. doi: 10.1016/j.ygyno.2017.04.012. Epub 2017 Apr 26.

13.

A High-Throughput Screening Model of the Tumor Microenvironment for Ovarian Cancer Cell Growth.

Lal-Nag M, McGee L, Guha R, Lengyel E, Kenny HA, Ferrer M.

SLAS Discov. 2017 Jun;22(5):494-506. doi: 10.1177/2472555216687082. Epub 2017 Jan 31.

14.

Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.

Chiyoda T, Hart PC, Eckert MA, McGregor SM, Lastra RR, Hamamoto R, Nakamura Y, Yamada SD, Olopade OI, Lengyel E, Romero IL.

Cancer Prev Res (Phila). 2017 Apr;10(4):255-266. doi: 10.1158/1940-6207.CAPR-16-0281. Epub 2017 Mar 6.

15.

Unsaturated Fatty Acids Maintain Cancer Cell Stemness.

Mukherjee A, Kenny HA, Lengyel E.

Cell Stem Cell. 2017 Mar 2;20(3):291-292. doi: 10.1016/j.stem.2017.02.008.

16.

Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity.

Sundaram KM, Zhang Y, Mitra AK, Kouadio JK, Gwin K, Kossiakoff AA, Roman BB, Lengyel E, Piccirilli JA.

Cancer Res. 2017 Apr 1;77(7):1684-1696. doi: 10.1158/0008-5472.CAN-16-1454. Epub 2017 Feb 15.

17.

Genomics of Ovarian Cancer Progression Reveals Diverse Metastatic Trajectories Including Intraepithelial Metastasis to the Fallopian Tube.

Eckert MA, Pan S, Hernandez KM, Loth RM, Andrade J, Volchenboum SL, Faber P, Montag A, Lastra R, Peter ME, Yamada SD, Lengyel E.

Cancer Discov. 2016 Dec;6(12):1342-1351. Epub 2016 Oct 7.

18.

Exosomes Promote Ovarian Cancer Cell Invasion through Transfer of CD44 to Peritoneal Mesothelial Cells.

Nakamura K, Sawada K, Kinose Y, Yoshimura A, Toda A, Nakatsuka E, Hashimoto K, Mabuchi S, Morishige KI, Kurachi H, Lengyel E, Kimura T.

Mol Cancer Res. 2017 Jan;15(1):78-92. doi: 10.1158/1541-7786.MCR-16-0191. Epub 2016 Oct 6.

19.

Metformin Targets Central Carbon Metabolism and Reveals Mitochondrial Requirements in Human Cancers.

Liu X, Romero IL, Litchfield LM, Lengyel E, Locasale JW.

Cell Metab. 2016 Nov 8;24(5):728-739. doi: 10.1016/j.cmet.2016.09.005. Epub 2016 Oct 13.

20.

Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.

Coscia F, Watters KM, Curtis M, Eckert MA, Chiang CY, Tyanova S, Montag A, Lastra RR, Lengyel E, Mann M.

Nat Commun. 2016 Aug 26;7:12645. doi: 10.1038/ncomms12645.

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