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Items: 9

1.

Alpha-methylated polyamines as potential drugs and experimental tools in enzymology.

Keinänen TA, Järvinen A, Uimari A, Vepsäläinen J, Khomutov AR, Grigorenko NA, Hyvönen MT, Cerrada-Gimenez M, Alhonen L, Jänne J.

Mini Rev Med Chem. 2007 Aug;7(8):813-20. Review.

PMID:
17692042
2.

Genetic manipulation of polyamine catabolism in rodents.

Jänne J, Alhonen L, Pietilä M, Keinänen TA, Uimari A, Hyvönen MT, Pirinen E, Järvinen A.

J Biochem. 2006 Feb;139(2):155-60. Review.

PMID:
16452302
3.

Alpha-methyl polyamines: efficient synthesis and tolerance studies in vivo and in vitro. First evidence for dormant stereospecificity of polyamine oxidase.

Järvinen AJ, Cerrada-Gimenez M, Grigorenko NA, Khomutov AR, Vepsäläinen JJ, Sinervirta RM, Keinänen TA, Alhonen LI, Jänne JE.

J Med Chem. 2006 Jan 12;49(1):399-406.

PMID:
16392825
4.

Animal disease models generated by genetic engineering of polyamine metabolism.

Jänne J, Alhonen L, Keinänen TA, Pietilä M, Uimari A, Pirinen E, Hyvönen MT, Järvinen A.

J Cell Mol Med. 2005 Oct-Dec;9(4):865-82. Review.

5.

Guide molecule-driven stereospecific degradation of alpha-methylpolyamines by polyamine oxidase.

Järvinen A, Keinänen TA, Grigorenko NA, Khomutov AR, Uimari A, Vepsäläinen J, Närvänen A, Alhonen L, Jänne J.

J Biol Chem. 2006 Feb 24;281(8):4589-95. Epub 2005 Dec 14.

6.

[New syntheses of alpha-methyl- and alpha,alpha'-dimethylspermine].

Grigorenko NA, Vepsalainen J, Jarvinen A, Keinanen TA, Alhonen L, Janne J, Khomutov AR.

Bioorg Khim. 2005 Mar-Apr;31(2):200-5. Russian.

PMID:
15889795
7.

Metabolic stability of alpha-methylated polyamine derivatives and their use as substitutes for the natural polyamines.

Järvinen A, Grigorenko N, Khomutov AR, Hyvönen MT, Uimari A, Vepsäläinen J, Sinervirta R, Keinänen TA, Vujcic S, Alhonen L, Porter CW, Jänne J.

J Biol Chem. 2005 Feb 25;280(8):6595-601. Epub 2004 Dec 16.

8.

[A new synthesis of alpha-methylspermidine].

Grigorenko NA, Vepsalainen J, Jarvinen A, Keinanen TA, Alhonen L, Janne J, Kritsyn AM, Khomutov AR.

Bioorg Khim. 2004 Jul-Aug;30(4):441-5. Russian.

PMID:
15469020
9.

Targeted disruption of spermidine/spermine N1-acetyltransferase gene in mouse embryonic stem cells. Effects on polyamine homeostasis and sensitivity to polyamine analogues.

Niiranen K, Pietilä M, Pirttilä TJ, Järvinen A, Halmekytö M, Korhonen VP, Keinänen TA, Alhonen L, Jänne J.

J Biol Chem. 2002 Jul 12;277(28):25323-8. Epub 2002 May 8.

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