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Items: 1 to 50 of 82

1.

Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen.

Deygas M, Gadet R, Gillet G, Rimokh R, Gonzalo P, Mikaelian I.

Nat Commun. 2018 Oct 31;9(1):4545. doi: 10.1038/s41467-018-06988-3.

2.

A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target.

Srivastava PK, van Eyll J, Godard P, Mazzuferi M, Delahaye-Duriez A, Steenwinckel JV, Gressens P, Danis B, Vandenplas C, Foerch P, Leclercq K, Mairet-Coello G, Cardenas A, Vanclef F, Laaniste L, Niespodziany I, Keaney J, Gasser J, Gillet G, Shkura K, Chong SA, Behmoaras J, Kadiu I, Petretto E, Kaminski RM, Johnson MR.

Nat Commun. 2018 Sep 3;9(1):3561. doi: 10.1038/s41467-018-06008-4.

3.

Improved IRE1 and PERK Pathway Sensors for Multiplex Endoplasmic Reticulum Stress Assay Reveal Stress Response to Nuclear Dyes Used for Image Segmentation.

Nougarède A, Tesnière C, Ylanko J, Rimokh R, Gillet G, Andrews DW.

Assay Drug Dev Technol. 2018 Aug/Sep;16(6):350-360. doi: 10.1089/adt.2018.862. Epub 2018 Aug 8.

PMID:
30088945
4.

Subcellular Localization and Dynamics of the Bcl-2 Family of Proteins.

Popgeorgiev N, Jabbour L, Gillet G.

Front Cell Dev Biol. 2018 Feb 13;6:13. doi: 10.3389/fcell.2018.00013. eCollection 2018. Review.

5.

Breast Cancer Targeting through Inhibition of the Endoplasmic Reticulum-Based Apoptosis Regulator Nrh/BCL2L10.

Nougarede A, Popgeorgiev N, Kassem L, Omarjee S, Borel S, Mikaelian I, Lopez J, Gadet R, Marcillat O, Treilleux I, Villoutreix BO, Rimokh R, Gillet G.

Cancer Res. 2018 Mar 15;78(6):1404-1417. doi: 10.1158/0008-5472.CAN-17-0846. Epub 2018 Jan 12.

PMID:
29330143
6.

Was Mesopithecus a seed eating colobine? Assessment of cracking, grinding and shearing ability using dental topography.

Thiery G, Gillet G, Lazzari V, Merceron G, Guy F.

J Hum Evol. 2017 Nov;112:79-92. doi: 10.1016/j.jhevol.2017.09.002. Epub 2017 Oct 7.

PMID:
29037418
7.

Mitochondrial Ca2+ uptake controls actin cytoskeleton dynamics during cell migration.

Prudent J, Popgeorgiev N, Gadet R, Deygas M, Rimokh R, Gillet G.

Sci Rep. 2016 Nov 9;6:36570. doi: 10.1038/srep36570.

8.

Bcl-2 proteins, cell migration and embryonic development: lessons from zebrafish.

Prudent J, Popgeorgiev N, Bonneau B, Gillet G.

Cell Death Dis. 2015 Oct 15;6:e1910. doi: 10.1038/cddis.2015.286. No abstract available.

9.

TIF1γ interferes with TGFβ1/SMAD4 signaling to promote poor outcome in operable breast cancer patients.

Kassem L, Deygas M, Fattet L, Lopez J, Goulvent T, Lavergne E, Chabaud S, Carrabin N, Chopin N, Bachelot T, Gillet G, Treilleux I, Rimokh R.

BMC Cancer. 2015 Jun 4;15:453. doi: 10.1186/s12885-015-1471-y.

10.

DICER1 and FOXL2 mutations in ovarian sex cord-stromal tumours: a GINECO Group study.

Goulvent T, Ray-Coquard I, Borel S, Haddad V, Devouassoux-Shisheboran M, Vacher-Lavenu MC, Pujade-Laurraine E, Savina A, Maillet D, Gillet G, Treilleux I, Rimokh R.

Histopathology. 2016 Jan;68(2):279-85. doi: 10.1111/his.12747. Epub 2015 Jul 21.

PMID:
26033501
11.

Combination of a discovery LC-MS/MS analysis and a label-free quantification for the characterization of an epithelial-mesenchymal transition signature.

Biarc J, Gonzalo P, Mikaelian I, Fattet L, Deygas M, Gillet G, Lemoine J, Rimokh R.

J Proteomics. 2014 Oct 14;110:183-94. doi: 10.1016/j.jprot.2014.05.026. Epub 2014 Jun 12.

PMID:
25242195
12.

SRC: marker or actor in prostate cancer aggressiveness.

Vlaeminck-Guillem V, Gillet G, Rimokh R.

Front Oncol. 2014 Aug 18;4:222. doi: 10.3389/fonc.2014.00222. eCollection 2014. Review.

13.

Nrz but not zBcl-xL antagonizes Bcl-wav pro-apoptotic activity in zebrafish.

Prudent J, Gillet G, Popgeorgiev N.

Commun Integr Biol. 2014 Jan 1;7(1):e28008. doi: 10.4161/cib.28008. Epub 2014 Feb 6.

14.

The Bcl-2 homolog Nrz inhibits binding of IP3 to its receptor to control calcium signaling during zebrafish epiboly.

Bonneau B, Nougarède A, Prudent J, Popgeorgiev N, Peyriéras N, Rimokh R, Gillet G.

Sci Signal. 2014 Feb 11;7(312):ra14. doi: 10.1126/scisignal.2004480.

PMID:
24518293
15.

Emulsification by high frequency ultrasound using piezoelectric transducer: formation and stability of emulsifier free emulsion.

Kaci M, Meziani S, Arab-Tehrany E, Gillet G, Desjardins-Lavisse I, Desobry S.

Ultrason Sonochem. 2014 May;21(3):1010-7. doi: 10.1016/j.ultsonch.2013.11.006. Epub 2013 Nov 20.

PMID:
24315670
16.

Genetic and pharmacologic inhibition of mTORC1 promotes EMT by a TGF-β-independent mechanism.

Mikaelian I, Malek M, Gadet R, Viallet J, Garcia A, Girard-Gagnepain A, Hesling C, Gillet G, Gonzalo P, Rimokh R, Billaud M.

Cancer Res. 2013 Nov 15;73(22):6621-31. doi: 10.1158/0008-5472.CAN-13-0560. Epub 2013 Sep 27.

17.

Bcl-wav and the mitochondrial calcium uniporter drive gastrula morphogenesis in zebrafish.

Prudent J, Popgeorgiev N, Bonneau B, Thibaut J, Gadet R, Lopez J, Gonzalo P, Rimokh R, Manon S, Houart C, Herbomel P, Aouacheria A, Gillet G.

Nat Commun. 2013;4:2330. doi: 10.1038/ncomms3330.

PMID:
23942336
18.

TIF1γ requires sumoylation to exert its repressive activity on TGFβ signaling.

Fattet L, Ay AS, Bonneau B, Jallades L, Mikaelian I, Treilleux I, Gillet G, Hesling C, Rimokh R.

J Cell Sci. 2013 Aug 15;126(Pt 16):3713-23. doi: 10.1242/jcs.126748. Epub 2013 Jun 20.

19.

Data-driven modeling of SRC control on the mitochondrial pathway of apoptosis: implication for anticancer therapy optimization.

Ballesta A, Lopez J, Popgeorgiev N, Gonzalo P, Doumic M, Gillet G.

PLoS Comput Biol. 2013 Apr;9(4):e1003011. doi: 10.1371/journal.pcbi.1003011. Epub 2013 Apr 4.

20.

Non-apoptotic roles of Bcl-2 family: the calcium connection.

Bonneau B, Prudent J, Popgeorgiev N, Gillet G.

Biochim Biophys Acta. 2013 Jul;1833(7):1755-65. doi: 10.1016/j.bbamcr.2013.01.021. Epub 2013 Jan 27. Review.

21.

Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition.

Hesling C, Lopez J, Fattet L, Gonzalo P, Treilleux I, Blanchard D, Losson R, Goffin V, Pigat N, Puisieux A, Mikaelian I, Gillet G, Rimokh R.

Development. 2013 Jan 1;140(1):167-75. doi: 10.1242/dev.085068. Epub 2012 Nov 15.

22.

Cytoskeleton dynamics in early zebrafish development: A matter of phosphorylation?

Bonneau B, Popgeorgiev N, Prudent J, Gillet G.

Bioarchitecture. 2011 Sep 1;1(5):216-220.

23.

µ-Calpain conversion of antiapoptotic Bfl-1 (BCL2A1) into a prodeath factor reveals two distinct alpha-helices inducing mitochondria-mediated apoptosis.

Valero JG, Cornut-Thibaut A, Jugé R, Debaud AL, Giménez D, Gillet G, Bonnefoy-Bérard N, Salgado J, Salles G, Aouacheria A, Kucharczak J.

PLoS One. 2012;7(6):e38620. doi: 10.1371/journal.pone.0038620. Epub 2012 Jun 20.

24.

Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik.

Lopez J, Hesling C, Prudent J, Popgeorgiev N, Gadet R, Mikaelian I, Rimokh R, Gillet G, Gonzalo P.

Cell Death Differ. 2012 Sep;19(9):1459-69. doi: 10.1038/cdd.2012.21. Epub 2012 Mar 2.

25.

A novel assay for the detection of anti-human platelet antigen antibodies (HPA-1a) based on peptide aptamer technology.

Thibaut J, Mérieux Y, Rigal D, Gillet G.

Haematologica. 2012 May;97(5):696-704. doi: 10.3324/haematol.2011.051276. Epub 2011 Dec 1.

26.

The yolk cell of the zebrafish blastula harbors functional apoptosis machinery.

Popgeorgiev N, Prudent J, Bonneau B, Gillet G.

Commun Integr Biol. 2011 Sep;4(5):549-551. doi: 10.4161/cib.4.5.16697. Epub 2011 Sep 1.

27.

Characterization of unique signature sequences in the divergent maternal protein Bcl2l10.

Guillemin Y, Cornut-Thibaut A, Gillet G, Penin F, Aouacheria A.

Mol Biol Evol. 2011 Dec;28(12):3271-83. doi: 10.1093/molbev/msr152. Epub 2011 Jun 24.

PMID:
21705382
28.

Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells.

Hesling C, Fattet L, Teyre G, Jury D, Gonzalo P, Lopez J, Vanbelle C, Morel AP, Gillet G, Mikaelian I, Rimokh R.

EMBO Rep. 2011 Jul 1;12(7):665-72. doi: 10.1038/embor.2011.78.

29.

The apoptotic regulator Nrz controls cytoskeletal dynamics via the regulation of Ca2+ trafficking in the zebrafish blastula.

Popgeorgiev N, Bonneau B, Ferri KF, Prudent J, Thibaut J, Gillet G.

Dev Cell. 2011 May 17;20(5):663-76. doi: 10.1016/j.devcel.2011.03.016.

30.

Bax-derived membrane-active peptides act as potent and direct inducers of apoptosis in cancer cells.

Valero JG, Sancey L, Kucharczak J, Guillemin Y, Gimenez D, Prudent J, Gillet G, Salgado J, Coll JL, Aouacheria A.

J Cell Sci. 2011 Feb 15;124(Pt 4):556-64. doi: 10.1242/jcs.076745. Epub 2011 Jan 18.

31.

Cellular processes of v-Src transformation revealed by gene profiling of primary cells--implications for human cancer.

Maślikowski BM, Néel BD, Wu Y, Wang L, Rodrigues NA, Gillet G, Bédard PA.

BMC Cancer. 2010 Feb 12;10:41. doi: 10.1186/1471-2407-10-41.

32.

Development of decision tools to assess migration from plastic materials in contact with food.

Gillet G, Vitrac O, Tissier D, Saillard P, Desobry S.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2009 Dec;26(12):1556-73.

PMID:
19938329
33.

Lithium suppresses motility and invasivity of v-src-transformed cells by glutathione-dependent activation of phosphotyrosine phosphatases.

Néel BD, Lopez J, Chabadel A, Gillet G.

Oncogene. 2009 Sep 10;28(36):3246-60. doi: 10.1038/onc.2009.190. Epub 2009 Jul 13.

PMID:
19597466
34.

Oocytes and early embryos selectively express the survival factor BCL2L10.

Guillemin Y, Lalle P, Gillet G, Guerin JF, Hamamah S, Aouacheria A.

J Mol Med (Berl). 2009 Sep;87(9):923-40. doi: 10.1007/s00109-009-0495-7. Epub 2009 Jun 24.

PMID:
19551325
35.

Modulating mitochondria-mediated apoptotic cell death through targeting of Bcl-2 family proteins.

Aouacheria A, Cibiel A, Guillemin Y, Gillet G, Lalle P.

Recent Pat DNA Gene Seq. 2007;1(1):43-61. Review.

PMID:
19075918
36.

Modulation of Nr-13 antideath activity by peptide aptamers.

Nouvion AL, Thibaut J, Lohez OD, Venet S, Colas P, Gillet G, Lalle P.

Oncogene. 2007 Feb 1;26(5):701-10. Epub 2006 Aug 14.

PMID:
16909120
37.

The zebrafish bcl-2 homologue Nrz controls development during somitogenesis and gastrulation via apoptosis-dependent and -independent mechanisms.

Arnaud E, Ferri KF, Thibaut J, Haftek-Terreau Z, Aouacheria A, Le Guellec D, Lorca T, Gillet G.

Cell Death Differ. 2006 Jul;13(7):1128-37. Epub 2005 Nov 11.

38.

Distinct protease pathways control cell shape and apoptosis in v-src-transformed quail neuroretina cells.

Néel BD, Aouacheria A, Nouvion AL, Ronot X, Gillet G.

Exp Cell Res. 2005 Nov 15;311(1):106-16. Epub 2005 Oct 3.

PMID:
16202997
39.

The ethical status of whistle-blowers.

Gillet G.

Monash Bioeth Rev. 2005 Jan;24(1):59-64. No abstract available.

PMID:
16007757
40.

Specific interaction of the antiapoptotic protein Nr-13 with phospholipid monolayers is prevented by the BH3 domain of Bax.

Girard-Egrot A, Chauvet JP, Gillet G, Moradi-Améli M.

J Mol Biol. 2004 Jan 2;335(1):321-31.

PMID:
14659760
41.

Characterization of vnr-13, the first alphaherpesvirus gene of the bcl-2 family.

Aouacheria A, Banyai M, Rigal D, Schmidt CJ, Gillet G.

Virology. 2003 Nov 25;316(2):256-66.

42.

Carbazolequinone induction of caspase-dependent cell death in Src-overexpressing cells.

Aouacheria A, Néel B, Bouaziz Z, Dominique R, Walchshofer N, Paris J, Fillion H, Gillet G.

Biochem Pharmacol. 2002 Dec 1;64(11):1605-16.

PMID:
12429350
43.

Evidence for crucial electrostatic interactions between Bcl-2 homology domains BH3 and BH4 in the anti-apoptotic Nr-13 protein.

Lalle P, Aouacheria A, Dumont-Miscopein A, Jambon M, Venet S, Bobichon H, Colas P, Deléage G, Geourjon C, Gillet G.

Biochem J. 2002 Nov 15;368(Pt 1):213-21.

44.

Interaction between the antiapoptotic protein Nr-13 and cytochrome c. Antagonistic effect of the BH3 domain of Bax.

Moradi-Améli M, Lorca T, Ficheux D, di Pietro A, Gillet G.

Biochemistry. 2002 Jul 9;41(27):8540-50.

PMID:
12093270
45.

p60(v-src) and serum control cell shape and apoptosis via distinct pathways in quail neuroretina cells.

Aouacheria A, Ory S, Schmitt JR, Rigal D, Jurdic P, Gillet G.

Oncogene. 2002 Feb 14;21(8):1171-86.

46.

Nrh, a human homologue of Nr-13 associates with Bcl-Xs and is an inhibitor of apoptosis.

Aouacheria A, Arnaud E, Venet S, Lalle P, Gouy M, Rigal D, Gillet G.

Oncogene. 2001 Sep 13;20(41):5846-55.

47.

Regulation of cdc2 gene expression by the upstream stimulatory factors (USFs).

North S, Espanel X, Bantignies F, Viollet B, Vallet V, Jalinot P, Brun G, Gillet G.

Oncogene. 1999 Mar 18;18(11):1945-55.

48.

Role of Nr13 in regulation of programmed cell death in the bursa of Fabricius.

Lee RM, Gillet G, Burnside J, Thomas SJ, Neiman P.

Genes Dev. 1999 Mar 15;13(6):718-28.

49.

Regulation of E2F-1 gene expression in avian cells.

Espanel X, Le Cam L, North S, Sardet C, Brun G, Gillet G.

Oncogene. 1998 Aug 6;17(5):585-94.

50.

p34(cdc2) and mitotic cyclin expression in the developing quail neuroretina.

Espanel X, Kastner A, Stettler O, Tavitian B, Brun G, Gillet G.

Int J Dev Biol. 1997 Jun;41(3):469-76.

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