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Items: 1 to 20 of 8058

1.

Involvement of pazopanib and sunitinib aldehyde reactive metabolites in toxicity and drug-drug interactions in vitro and in patient samples.

Paludetto MN, Stigliani JL, Robert A, Bernardes-Genisson V, Chatelut E, Puisset F, Arellano C.

Chem Res Toxicol. 2019 Sep 19. doi: 10.1021/acs.chemrestox.9b00205. [Epub ahead of print]

PMID:
31535851
2.

Predicting Drug-Induced Liver Injury with Bayesian Machine Learning.

Williams DP, Lazic S, Foster AJ, Semenova E, Morgan P.

Chem Res Toxicol. 2019 Sep 19. doi: 10.1021/acs.chemrestox.9b00264. [Epub ahead of print]

PMID:
31535850
3.

The Variant at TGFBRAP1 but Not TGFBR2 Is Associated with Antituberculosis Drug-Induced Liver Injury.

Zhang J, Zhao Z, Bai H, Jiao L, Wu Q, Wu T, Liu T, Hu X, Song J, Lyv M, Ying B.

Evid Based Complement Alternat Med. 2019 Aug 22;2019:1685128. doi: 10.1155/2019/1685128. eCollection 2019.

4.

MOVING BEYOND BINARY PREDICTIONS OF HUMAN DRUG-INDUCED LIVER INJURY (DILI) TOWARDS CONTRASTING RELATIVE RISK POTENTIAL.

Aleo MD, Shah F, Allen S, Barton HA, Costales C, Lazzaro S, Leung L, Nilson A, Obach RS, Rodrigues AD, Will Y.

Chem Res Toxicol. 2019 Sep 18. doi: 10.1021/acs.chemrestox.9b00262. [Epub ahead of print]

PMID:
31532188
5.

Metabolic Comorbidities and Risk of Development and Severity of Drug-Induced Liver Injury.

Li X, Gao P, Niu J.

Biomed Res Int. 2019 Aug 18;2019:8764093. doi: 10.1155/2019/8764093. eCollection 2019. Review.

6.

Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells.

Martí-Rodrigo A, Alegre F, Moragrega ÁB, García-García F, Martí-Rodrigo P, Fernández-Iglesias A, Gracia-Sancho J, Apostolova N, Esplugues JV, Blas-García A.

Gut. 2019 Sep 17. pii: gutjnl-2019-318372. doi: 10.1136/gutjnl-2019-318372. [Epub ahead of print]

PMID:
31530714
7.

Hypoxia-Inducible Factor (HIF)-2α Reprograms Liver Macrophages to Protect Against Acute Liver Injury via the Production of Interleukin-6.

Gao RY, Wang M, Liu Q, Feng D, Wen Y, Xia Y, Colgan SP, Eltzschig HK, Ju C.

Hepatology. 2019 Sep 17. doi: 10.1002/hep.30954. [Epub ahead of print]

PMID:
31529728
8.

Kratom-Induced Cholestatic Liver Injury Mimicking Anti-Mitochondrial Antibody-Negative Primary Biliary Cholangitis: A Case Report and Review of Literature.

Aldyab M, Ells PF, Bui R, Chapman TD, Lee H.

Gastroenterology Res. 2019 Aug;12(4):211-215. doi: 10.14740/gr1204. Epub 2019 Aug 25.

9.

Fenofibrate-induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database.

Ma S, Liu S, Wang Q, Chen L, Yang P, Sun H.

J Clin Pharm Ther. 2019 Sep 13. doi: 10.1111/jcpt.13042. [Epub ahead of print]

PMID:
31518450
10.

Autoimmune hepatitis in patients with human immunodeficiency virus infection: A systematic review of the published literature.

Mubder M, Azab M, Jayaraj M, Cross C, Lankarani D, Dhindsa B, Pan JJ, Ohning G.

Medicine (Baltimore). 2019 Sep;98(37):e17094. doi: 10.1097/MD.0000000000017094.

11.

Histone methyltransferase G9a protects against acute liver injury through GSTP1.

Zhang Y, Xue W, Zhang W, Yuan Y, Zhu X, Wang Q, Wei Y, Yang D, Yang C, Chen Y, Sun Y, Wang S, Huang K, Zheng L.

Cell Death Differ. 2019 Sep 12. doi: 10.1038/s41418-019-0412-8. [Epub ahead of print]

PMID:
31515511
12.

Nationwide analysis of treatment outcomes in children and adolescents routinely treated for tuberculosis in The Netherlands.

Gafar F, Van't Boveneind-Vrubleuskaya N, Akkerman OW, Wilffert B, Alffenaar JC.

Eur Respir J. 2019 Sep 12. pii: 1901402. doi: 10.1183/13993003.01402-2019. [Epub ahead of print]

PMID:
31515410
13.

A hepatoprotection study of Radix Bupleuri on acetaminophen-induced liver injury based on CYP450 inhibition.

Wang YX, DU Y, Liu XF, Yang FX, Wu X, Tan L, Lu YH, Zhang JW, Zhou F, Wang GJ.

Chin J Nat Med. 2019 Jul;17(7):517-524. doi: 10.1016/S1875-5364(19)30073-1.

PMID:
31514983
14.

Comprehensive Evaluation of Bile Acid Homeostasis in Human Hepatocyte Co-Culture in the Presence of Troglitazone, Pioglitazone and Acetylsalicylic Acid.

Chang JH, Sangaraju D, Liu N, Jaochico A, Plise E.

Mol Pharm. 2019 Sep 11. doi: 10.1021/acs.molpharmaceut.9b00562. [Epub ahead of print]

PMID:
31509422
15.

Local and systemic effects caused by Crotalus durissus terrificus, Crotalus durissus collilineatus, and Crotalus durissus cascavella snake venoms in swiss mice.

Carvalho LH, Teixeira LF, Zaqueo KD, Bastos JF, Nery NM, Setúbal SS, Pontes AS, Butzke D, Cavalcante W, Gallacci M, Fernandes CFC, Stabeli RG, Soares AM, Zuliani JP.

Rev Soc Bras Med Trop. 2019 Sep 5;52:e20180526. doi: 10.1590/0037-8682-0526-2018.

16.

Identification of Candidate Risk Factor Genes for Human Idelalisib Toxicity Using a Collaborative Cross Approach.

Mosedale M, Cai Y, Eaddy JS, Corty RW, Nautiyal M, Watkins PB, Valdar W.

Toxicol Sci. 2019 Sep 10. pii: kfz199. doi: 10.1093/toxsci/kfz199. [Epub ahead of print]

PMID:
31501888
17.

Acute liver failure.

Stravitz RT, Lee WM.

Lancet. 2019 Sep 7;394(10201):869-881. doi: 10.1016/S0140-6736(19)31894-X. Review.

PMID:
31498101
18.

A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice.

Wang X, Sommerfeld MR, Jahn-Hofmann K, Cai B, Filliol A, Remotti HE, Schwabe RF, Kannt A, Tabas I.

Hepatol Commun. 2019 Jul 23;3(9):1221-1234. doi: 10.1002/hep4.1405. eCollection 2019 Sep.

19.

A Rare Case of Drug-Induced Liver Injury Caused by Levetiracetam.

Kawaguchi T, Tominaga T.

Asian J Neurosurg. 2019 Jul-Sep;14(3):878-882. doi: 10.4103/ajns.AJNS_246_17.

20.

Quantitative Evaluation of Reactivity and Toxicity of Acyl Glucuronides by [35S]Cysteine Trapping.

Harada H, Toyoda Y, Abe Y, Endo T, Takeda H.

Chem Res Toxicol. 2019 Sep 9. doi: 10.1021/acs.chemrestox.9b00111. [Epub ahead of print]

PMID:
31496220

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