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Items: 20


Predictors of sick leave and improved worker productivity after 52 weeks of intensive treatment in patients with early rheumatoid arthritis.

Blomjous BS, Boers M, Den Uyl D, Twisk J, Van Schaardenburg D, Voskuyl AE, Lems WF, Ter Wee MM.

Scand J Rheumatol. 2019 Jul;48(4):271-278. doi: 10.1080/03009742.2019.1570549. Epub 2019 May 28.


Cost-utility of COBRA-light versus COBRA therapy in patients with early rheumatoid arthritis: the COBRA-light trial.

Ter Wee MM, Coupé VM, den Uyl D, Blomjous BS, Kooijmans E, Kerstens PJ, Nurmohamed MT, van Schaardenburg D, Voskuyl AE, Boers M, Lems WF.

RMD Open. 2017 Oct 25;3(2):e000502. doi: 10.1136/rmdopen-2017-000502. eCollection 2017.


Similar efficacy and safety of initial COBRA-light and COBRA therapy in rheumatoid arthritis: 4-year results from the COBRA-light trial.

Konijn NPC, van Tuyl LHD, Boers M, den Uyl D, Ter Wee MM, van der Wijden LKM, Bultink IEM, Kerstens PJSM, Voskuyl AE, van Schaardenburg D, Nurmohamed MT, Lems WF.

Rheumatology (Oxford). 2017 Sep 1;56(9):1586-1596. doi: 10.1093/rheumatology/kex223.


Do Short and Sustained Periods of American College of Rheumatology/European League Against Rheumatism Remission Predict Functional and Radiographic Outcome in Early Rheumatoid Arthritis Patients With Low Overall Damage Progression?

Konijn NPC, van Tuyl LHD, Boers M, den Uyl D, Ter Wee MM, Kerstens P, Voskuyl AE, van Schaardenburg D, Nurmohamed MT, Lems WF.

Arthritis Care Res (Hoboken). 2017 Jul;69(7):989-996. doi: 10.1002/acr.23112. Epub 2017 Jun 7.


The short-term effects of two high-dose, step-down prednisolone regimens on body composition in early rheumatoid arthritis.

Konijn NP, van Tuyl LH, Boers M, van de Ven PM, den Uyl D, Ter Wee MM, Kerstens P, Voskuyl AE, van Schaardenburg D, Lems WF, Nurmohamed MT.

Rheumatology (Oxford). 2016 Sep;55(9):1615-22. doi: 10.1093/rheumatology/kew221. Epub 2016 May 31.


Subclinical synovitis detected by macrophage PET, but not MRI, is related to short-term flare of clinical disease activity in early RA patients: an exploratory study.

Gent YY, Ter Wee MM, Voskuyl AE, den Uyl D, Ahmadi N, Dowling C, van Kuijk C, Hoekstra OS, Boers M, Lems WF, van der Laken CJ.

Arthritis Res Ther. 2015 Sep 25;17:266. doi: 10.1186/s13075-015-0770-7.


Effective Treatment for Rapid Improvement of Both Disease Activity and Self-Reported Physical Activity in Early Rheumatoid Arthritis.

Konijn NP, van Tuyl LH, Boers M, den Uyl D, Ter Wee MM, Kerstens P, Voskuyl AE, Nurmohamed M, van Schaardenburg D, Lems WF.

Arthritis Care Res (Hoboken). 2016 Feb;68(2):280-4. doi: 10.1002/acr.22668.


Low grade inflammation is associated with lower velocity of sound and broadband ultrasound attenuation in older men, but not with bone loss or fracture risk in a longitudinal aging study.

den Uyl D, van Schoor NM, Bravenboer N, Lips P, Lems WF.

Bone. 2015 Dec;81:270-276. doi: 10.1016/j.bone.2015.07.017. Epub 2015 Jul 16.


Intensive combination treatment regimens, including prednisolone, are effective in treating patients with early rheumatoid arthritis regardless of additional etanercept: 1-year results of the COBRA-light open-label, randomised, non-inferiority trial.

ter Wee MM, den Uyl D, Boers M, Kerstens P, Nurmohamed M, van Schaardenburg D, Voskuyl AE, Lems WF.

Ann Rheum Dis. 2015 Jun;74(6):1233-40. doi: 10.1136/annrheumdis-2013-205143. Epub 2014 May 12.


Water lubricates hydrogen-bonded molecular machines.

Panman MR, Bakker BH, den Uyl D, Kay ER, Leigh DA, Buma WJ, Brouwer AM, Geenevasen JA, Woutersen S.

Nat Chem. 2013 Nov;5(11):929-34. doi: 10.1038/nchem.1744. Epub 2013 Sep 1.


A non-inferiority trial of an attenuated combination strategy ('COBRA-light') compared to the original COBRA strategy: clinical results after 26 weeks.

den Uyl D, ter Wee M, Boers M, Kerstens P, Voskuyl A, Nurmohamed M, Raterman H, van Schaardenburg D, van Dillen N, Dijkmans B, Lems W.

Ann Rheum Dis. 2014 Jun;73(6):1071-8. doi: 10.1136/annrheumdis-2012-202818. Epub 2013 Apr 19.


Inactivating PSMB5 mutations and P-glycoprotein (multidrug resistance-associated protein/ATP-binding cassette B1) mediate resistance to proteasome inhibitors: ex vivo efficacy of (immuno)proteasome inhibitors in mononuclear blood cells from patients with rheumatoid arthritis.

Verbrugge SE, Assaraf YG, Dijkmans BA, Scheffer GL, Al M, den Uyl D, Oerlemans R, Chan ET, Kirk CJ, Peters GJ, van der Heijden JW, de Gruijl TD, Scheper RJ, Jansen G.

J Pharmacol Exp Ther. 2012 Apr;341(1):174-82. doi: 10.1124/jpet.111.187542. Epub 2012 Jan 10.


Glucocorticoid-induced osteoporosis.

den Uyl D, Bultink IE, Lems WF.

Clin Exp Rheumatol. 2011 Sep-Oct;29(5 Suppl 68):S93-8. Epub 2011 Oct 21. Review.


Metabolic effects of high-dose prednisolone treatment in early rheumatoid arthritis: balance between diabetogenic effects and inflammation reduction.

den Uyl D, van Raalte DH, Nurmohamed MT, Lems WF, Bijlsma JW, Hoes JN, Dijkmans BA, Diamant M.

Arthritis Rheum. 2012 Mar;64(3):639-46. doi: 10.1002/art.33378.


Glucose tolerance, insulin sensitivity and β-cell function in patients with rheumatoid arthritis treated with or without low-to-medium dose glucocorticoids.

Hoes JN, van der Goes MC, van Raalte DH, van der Zijl NJ, den Uyl D, Lems WF, Lafeber FP, Jacobs JW, Welsing PM, Diamant M, Bijlsma JW.

Ann Rheum Dis. 2011 Nov;70(11):1887-94. doi: 10.1136/ard.2011.151464. Epub 2011 Sep 10.


Advances in glucocorticoid-induced osteoporosis.

den Uyl D, Bultink IE, Lems WF.

Curr Rheumatol Rep. 2011 Jun;13(3):233-40. doi: 10.1007/s11926-011-0173-y. Review.


(Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis.

den Uyl D, Nurmohamed MT, van Tuyl LH, Raterman HG, Lems WF.

Arthritis Res Ther. 2011 Jan 17;13(1):R5. doi: 10.1186/ar3224. Review.


Exercise-induced changes in interleukin-10 in patients with knee osteoarthritis: new perspectives?

Lems WF, den Uyl D.

Arthritis Res Ther. 2010;12(4):131. doi: 10.1186/ar3084. Epub 2010 Jul 29.


Patient preference and acceptability of calcium plus vitamin D3 supplementation: a randomised, open, cross-over trial.

den Uyl D, Geusens PP, van Berkum FN, Houben HH, Jebbink MC, Lems WF.

Clin Rheumatol. 2010 May;29(5):465-72. doi: 10.1007/s10067-009-1328-3. Epub 2009 Dec 22.


Progression of HIV to AIDS: a protective role for HLA-B27?

den Uyl D, van der Horst-Bruinsma IE, van Agtmael M.

AIDS Rev. 2004 Apr-Jun;6(2):89-96. Review.


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