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Items: 29


Human papillomavirus oncogenes reprogram the cervical cancer microenvironment independently of and synergistically with estrogen.

Spurgeon ME, den Boon JA, Horswill M, Barthakur S, Forouzan O, Rader JS, Beebe DJ, Roopra A, Ahlquist P, Lambert PF.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9076-E9085. doi: 10.1073/pnas.1712018114. Epub 2017 Oct 9.


Cryo-electron tomography reveals novel features of a viral RNA replication compartment.

Ertel KJ, Benefield D, CastaƱo-Diez D, Pennington JG, Horswill M, den Boon JA, Otegui MS, Ahlquist P.

Elife. 2017 Jun 27;6. pii: e25940. doi: 10.7554/eLife.25940.


Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer.

Bodelon C, Vinokurova S, Sampson JN, den Boon JA, Walker JL, Horswill MA, Korthauer K, Schiffman M, Sherman ME, Zuna RE, Mitchell J, Zhang X, Boland JF, Chaturvedi AK, Dunn ST, Newton MA, Ahlquist P, Wang SS, Wentzensen N.

Carcinogenesis. 2016 Feb;37(2):188-196. doi: 10.1093/carcin/bgv171. Epub 2015 Dec 9. No abstract available.


Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling.

den Boon JA, Pyeon D, Wang SS, Horswill M, Schiffman M, Sherman M, Zuna RE, Wang Z, Hewitt SM, Pearson R, Schott M, Chung L, He Q, Lambert P, Walker J, Newton MA, Wentzensen N, Ahlquist P.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):E3255-64. doi: 10.1073/pnas.1509322112. Epub 2015 Jun 8.


Intersection of the multivesicular body pathway and lipid homeostasis in RNA replication by a positive-strand RNA virus.

Wang X, Diaz A, Hao L, Gancarz B, den Boon JA, Ahlquist P.

J Virol. 2011 Jun;85(11):5494-503. doi: 10.1128/JVI.02031-10. Epub 2011 Mar 23.


Organelle-like membrane compartmentalization of positive-strand RNA virus replication factories.

den Boon JA, Ahlquist P.

Annu Rev Microbiol. 2010;64:241-56. doi: 10.1146/annurev.micro.112408.134012. Review.


Cytoplasmic viral replication complexes.

den Boon JA, Diaz A, Ahlquist P.

Cell Host Microbe. 2010 Jul 22;8(1):77-85. doi: 10.1016/j.chom.2010.06.010. Review.


An amphipathic alpha-helix controls multiple roles of brome mosaic virus protein 1a in RNA replication complex assembly and function.

Liu L, Westler WM, den Boon JA, Wang X, Diaz A, Steinberg HA, Ahlquist P.

PLoS Pathog. 2009 Mar;5(3):e1000351. doi: 10.1371/journal.ppat.1000351. Epub 2009 Mar 27.


MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins.

Sengupta S, den Boon JA, Chen IH, Newton MA, Stanhope SA, Cheng YJ, Chen CJ, Hildesheim A, Sugden B, Ahlquist P.

Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5874-8. doi: 10.1073/pnas.0801130105. Epub 2008 Apr 4.


Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers.

Pyeon D, Newton MA, Lambert PF, den Boon JA, Sengupta S, Marsit CJ, Woodworth CD, Connor JP, Haugen TH, Smith EM, Kelsey KT, Turek LP, Ahlquist P.

Cancer Res. 2007 May 15;67(10):4605-19.


Genes involved in DNA repair and nitrosamine metabolism and those located on chromosome 14q32 are dysregulated in nasopharyngeal carcinoma.

Dodd LE, Sengupta S, Chen IH, den Boon JA, Cheng YJ, Westra W, Newton MA, Mittl BF, McShane L, Chen CJ, Ahlquist P, Hildesheim A.

Cancer Epidemiol Biomarkers Prev. 2006 Nov;15(11):2216-25.


Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma.

Sengupta S, den Boon JA, Chen IH, Newton MA, Dahl DB, Chen M, Cheng YJ, Westra WH, Chen CJ, Hildesheim A, Sugden B, Ahlquist P.

Cancer Res. 2006 Aug 15;66(16):7999-8006.


Lack of association between EBV and breast carcinoma.

Perrigoue JG, den Boon JA, Friedl A, Newton MA, Ahlquist P, Sugden B.

Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):809-14.


An infectious arterivirus cDNA clone: identification of a replicase point mutation that abolishes discontinuous mRNA transcription.

van Dinten LC, den Boon JA, Wassenaar AL, Spaan WJ, Snijder EJ.

Proc Natl Acad Sci U S A. 1997 Feb 4;94(3):991-6.


Processing and evolution of the N-terminal region of the arterivirus replicase ORF1a protein: identification of two papainlike cysteine proteases.

den Boon JA, Faaberg KS, Meulenberg JJ, Wassenaar AL, Plagemann PG, Gorbalenya AE, Snijder EJ.

J Virol. 1995 Jul;69(7):4500-5.


Proteolytic processing of the arterivirus replicase.

Snijder E, Wassenaar AL, Den Boon JA, Spaan WJ.

Adv Exp Med Biol. 1995;380:443-51. Review. No abstract available.


Responsiveness of the increase in C-fos mRNA levels depends on the inducer and the cell's past.

Tuijl MJ, Den Boon JA, Van Grunsven WM, Van Wijk R.

J Cell Physiol. 1991 Oct;149(1):44-9.


Characterization of defective interfering RNAs of Berne virus.

Snijder EJ, den Boon JA, Horzinek MC, Spaan WJ.

J Gen Virol. 1991 Jul;72 ( Pt 7):1635-43.


Another triple-spanning envelope protein among intracellularly budding RNA viruses: the torovirus E protein.

Den Boon JA, Snijder EJ, Locker JK, Horzinek MC, Rottier PJ.

Virology. 1991 Jun;182(2):655-63.


Equine arteritis virus is not a togavirus but belongs to the coronaviruslike superfamily.

den Boon JA, Snijder EJ, Chirnside ED, de Vries AA, Horzinek MC, Spaan WJ.

J Virol. 1991 Jun;65(6):2910-20.


Primary structure and post-translational processing of the Berne virus peplomer protein.

Snijder EJ, Den Boon JA, Spaan WJ, Weiss M, Horzinek MC.

Virology. 1990 Oct;178(2):355-63.


The polymerase gene of corona- and toroviruses: evidence for an evolutionary relationship.

Bredenbeek PJ, Snijder EJ, Noten FH, den Boon JA, Schaaper WM, Horzinek MC, Spaan WJ.

Adv Exp Med Biol. 1990;276:307-16.


Identification and primary structure of the gene encoding the Berne virus nucleocapsid protein.

Snijder EJ, den Boon JA, Spaan WJ, Verjans GM, Horzinek MC.

J Gen Virol. 1989 Dec;70 ( Pt 12):3363-70.


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