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Items: 28


Translation of cancer immunotherapy from the bench to the bedside.

Guo Q, Huang F, Goncalves C, Del Rincón SV, Miller WH Jr.

Adv Cancer Res. 2019;143:1-62. doi: 10.1016/bs.acr.2019.03.001. Epub 2019 May 2.


CKS1 Germ Line Exclusion Is Essential for the Transition from Meiosis to Early Embryonic Development.

Ellederova Z, Del Rincon S, Koncicka M, Susor A, Kubelka M, Sun D, Spruck C.

Mol Cell Biol. 2019 Jun 13;39(13). pii: e00590-18. doi: 10.1128/MCB.00590-18. Print 2019 Jul 1.


MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ.

Guo Q, Li VZ, Nichol JN, Huang F, Yang W, Preston SEJ, Talat Z, Lefrère H, Yu H, Zhang G, Basik M, Gonçalves C, Zhan Y, Plourde D, Su J, Torres J, Marques M, Habyan SA, Bijian K, Amant F, Witcher M, Behbod F, McCaffrey L, Alaoui-Jamali M, Giannakopoulos NV, Brackstone M, Postovit LM, Del Rincón SV, Miller WH Jr.

Cancer Res. 2019 Apr 1;79(7):1646-1657. doi: 10.1158/0008-5472.CAN-18-1602. Epub 2019 Jan 18.


Oncogenic activity of poly (ADP-ribose) glycohydrolase.

Marques M, Jangal M, Wang LC, Kazanets A, da Silva SD, Zhao T, Lovato A, Yu H, Jie S, Del Rincon S, Mackey J, Damaraju S, Alaoui-Jamali M, Witcher M.

Oncogene. 2019 Mar;38(12):2177-2191. doi: 10.1038/s41388-018-0568-6. Epub 2018 Nov 20.


Peroxisomes and cancer: The role of a metabolic specialist in a disease of aberrant metabolism.

Dahabieh MS, Di Pietro E, Jangal M, Goncalves C, Witcher M, Braverman NE, Del Rincón SV.

Biochim Biophys Acta Rev Cancer. 2018 Aug;1870(1):103-121. doi: 10.1016/j.bbcan.2018.07.004. Epub 2018 Aug 6. Review.


Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils.

Robichaud N, Hsu BE, Istomine R, Alvarez F, Blagih J, Ma EH, Morales SV, Dai DL, Li G, Souleimanova M, Guo Q, Del Rincon SV, Miller WH Jr, Ramón Y Cajal S, Park M, Jones RG, Piccirillo CA, Siegel PM, Sonenberg N.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2202-E2209. doi: 10.1073/pnas.1717439115. Epub 2018 Feb 20.


The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity.

Zahreddine HA, Culjkovic-Kraljacic B, Emond A, Pettersson F, Midura R, Lauer M, Del Rincon S, Cali V, Assouline S, Miller WH, Hascall V, Borden KL.

Elife. 2017 Nov 7;6. pii: e29830. doi: 10.7554/eLife.29830.


MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma.

Zhan Y, Guo J, Yang W, Goncalves C, Rzymski T, Dreas A, Żyłkiewicz E, Mikulski M, Brzózka K, Golas A, Kong Y, Ma M, Huang F, Huor B, Guo Q, da Silva SD, Torres J, Cai Y, Topisirovic I, Su J, Bijian K, Alaoui-Jamali MA, Huang S, Journe F, Ghanem GE, Miller WH Jr, Del Rincón SV.

J Clin Invest. 2017 Nov 1;127(11):4179-4192. doi: 10.1172/JCI91258. Epub 2017 Oct 16.


Peroxisomes protect lymphoma cells from HDAC inhibitor-mediated apoptosis.

Dahabieh MS, Ha Z, Di Pietro E, Nichol JN, Bolt AM, Goncalves C, Dupéré-Richer D, Pettersson F, Mann KK, Braverman NE, Del Rincón SV, Miller WH Jr.

Cell Death Differ. 2017 Nov;24(11):1912-1924. doi: 10.1038/cdd.2017.115. Epub 2017 Jul 21.


Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I.

Peña-Hernández R, Marques M, Hilmi K, Zhao T, Saad A, Alaoui-Jamali MA, del Rincon SV, Ashworth T, Roy AL, Emerson BM, Witcher M.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E677-86. doi: 10.1073/pnas.1416674112. Epub 2015 Feb 2.


The role of eIF4E in response and acquired resistance to vemurafenib in melanoma.

Zhan Y, Dahabieh MS, Rajakumar A, Dobocan MC, M'Boutchou MN, Goncalves C, Lucy SL, Pettersson F, Topisirovic I, van Kempen L, Del Rincón SV, Miller WH Jr.

J Invest Dermatol. 2015 May;135(5):1368-1376. doi: 10.1038/jid.2015.11. Epub 2015 Jan 23.


Genetic and pharmacologic inhibition of eIF4E reduces breast cancer cell migration, invasion, and metastasis.

Pettersson F, Del Rincon SV, Emond A, Huor B, Ngan E, Ng J, Dobocan MC, Siegel PM, Miller WH Jr.

Cancer Res. 2015 Mar 15;75(6):1102-12. doi: 10.1158/0008-5472.CAN-14-1996. Epub 2015 Jan 21.


Eukaryotic translation initiation factor 4E as a novel therapeutic target in hematological malignancies and beyond.

Pettersson F, Del Rincon SV, Miller WH Jr.

Expert Opin Ther Targets. 2014 Sep;18(9):1035-48. doi: 10.1517/14728222.2014.937426. Epub 2014 Jul 8. Review.


Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3.

Robichaud N, del Rincon SV, Huor B, Alain T, Petruccelli LA, Hearnden J, Goncalves C, Grotegut S, Spruck CH, Furic L, Larsson O, Muller WJ, Miller WH, Sonenberg N.

Oncogene. 2015 Apr 16;34(16):2032-42. doi: 10.1038/onc.2014.146. Epub 2014 Jun 9.


Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints.

del Rincón SV, Widschwendter M, Sun D, Ekholm-Reed S, Tat J, Teixeira LK, Ellederova Z, Grolieres E, Reed SI, Spruck C.

Oncogene. 2015 Apr 9;34(15):1961-7. doi: 10.1038/onc.2014.137. Epub 2014 May 26.


Gallotannin imposes S phase arrest in breast cancer cells and suppresses the growth of triple-negative tumors in vivo.

Zhao T, Sun Q, del Rincon SV, Lovato A, Marques M, Witcher M.

PLoS One. 2014 Mar 21;9(3):e92853. doi: 10.1371/journal.pone.0092853. eCollection 2014.


The novel arsenical darinaparsin is transported by cystine importing systems.

Garnier N, Redstone GG, Dahabieh MS, Nichol JN, del Rincon SV, Gu Y, Bohle DS, Sun Y, Conklin DS, Mann KK, Miller WH Jr.

Mol Pharmacol. 2014 Apr;85(4):576-85. doi: 10.1124/mol.113.089433. Epub 2014 Jan 15.


Coordinate transcriptional and translational repression of p53 by TGF-β1 impairs the stress response.

López-Díaz FJ, Gascard P, Balakrishnan SK, Zhao J, Del Rincon SV, Spruck C, Tlsty TD, Emerson BM.

Mol Cell. 2013 May 23;50(4):552-64. doi: 10.1016/j.molcel.2013.04.029.


Expression of leukemia-associated fusion proteins increases sensitivity to histone deacetylase inhibitor-induced DNA damage and apoptosis.

Petruccelli LA, Pettersson F, Del Rincón SV, Guilbert C, Licht JD, Miller WH Jr.

Mol Cancer Ther. 2013 Aug;12(8):1591-604. doi: 10.1158/1535-7163.MCT-12-1039. Epub 2013 Mar 27.


The novel arsenical Darinaparsin circumvents BRG1-dependent, HO-1-mediated cytoprotection in leukemic cells.

Garnier N, Petruccelli LA, Molina MF, Kourelis M, Kwan S, Diaz Z, Schipper HM, Gupta A, del Rincon SV, Mann KK, Miller WH Jr.

Leukemia. 2013 Nov;27(11):2220-8. doi: 10.1038/leu.2013.54. Epub 2013 Feb 21.


Vorinostat-induced autophagy switches from a death-promoting to a cytoprotective signal to drive acquired resistance.

Dupéré-Richer D, Kinal M, Ménasché V, Nielsen TH, Del Rincon S, Pettersson F, Miller WH Jr.

Cell Death Dis. 2013 Feb 7;4:e486. doi: 10.1038/cddis.2012.210.


Development and validation of a method for profiling post-translational modification activities using protein microarrays.

Del Rincón SV, Rogers J, Widschwendter M, Sun D, Sieburg HB, Spruck C.

PLoS One. 2010 Jun 28;5(6):e11332. doi: 10.1371/journal.pone.0011332.


Retinoic acid mediates degradation of IRS-1 by the ubiquitin-proteasome pathway, via a PKC-dependant mechanism.

del Rincón SV, Guo Q, Morelli C, Shiu HY, Surmacz E, Miller WH.

Oncogene. 2004 Dec 9;23(57):9269-79.


Expression of SMRTbeta promotes ligand-induced activation of mutated and wild-type retinoid receptors.

Côté S, McNamara S, Brambilla D, Bianchini A, Rizzo G, del Rincón SV, Grignani F, Nervi C, Miller WH Jr.

Blood. 2004 Dec 15;104(13):4226-35. Epub 2004 Aug 19.


Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters.

Morelli C, Garofalo C, Sisci D, del Rincon S, Cascio S, Tu X, Vecchione A, Sauter ER, Miller WH Jr, Surmacz E.

Oncogene. 2004 Sep 30;23(45):7517-26.


Retinoic acid-induced growth arrest of MCF-7 cells involves the selective regulation of the IRS-1/PI 3-kinase/AKT pathway.

del Rincón SV, Rousseau C, Samanta R, Miller WH Jr.

Oncogene. 2003 May 29;22(22):3353-60.


Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformation.

Aznar S, Valerón PF, del Rincon SV, Pérez LF, Perona R, Lacal JC.

Mol Biol Cell. 2001 Oct;12(10):3282-94.

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