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Items: 44

1.

Lis1 dysfunction leads to traction force reduction and cytoskeletal disorganization during cell migration.

Jheng GW, Hur SS, Chang CM, Wu CC, Cheng JS, Lee HH, Chung BC, Wang YK, Lin KH, Del Álamo JC, Chien S, Tsai JW.

Biochem Biophys Res Commun. 2018 Mar 11;497(3):869-875. doi: 10.1016/j.bbrc.2018.02.151. Epub 2018 Feb 20.

PMID:
29470990
2.

Three-dimensional forces exerted by leukocytes and vascular endothelial cells dynamically facilitate diapedesis.

Yeh YT, Serrano R, François J, Chiu JJ, Li YJ, Del Álamo JC, Chien S, Lasheras JC.

Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):133-138. doi: 10.1073/pnas.1717489115. Epub 2017 Dec 18.

3.

Stasis Mapping Using Ultrasound: A Prospective Study in Acute Myocardial Infarction.

Martinez-Legazpi P, Rossini L, Pérez Del Villar C, Benito Y, Devesa-Cordero C, Yotti R, Delgado-Montero A, Gonzalez-Mansilla A, Kahn AM, Fernandez-Avilés F, Del Álamo JC, Bermejo J.

JACC Cardiovasc Imaging. 2018 Mar;11(3):514-515. doi: 10.1016/j.jcmg.2017.06.012. Epub 2017 Oct 5. No abstract available.

PMID:
28917683
4.

Mechanosensitive Adhesion Explains Stepping Motility in Amoeboid Cells.

Copos CA, Walcott S, Del Álamo JC, Bastounis E, Mogilner A, Guy RD.

Biophys J. 2017 Jun 20;112(12):2672-2682. doi: 10.1016/j.bpj.2017.04.033.

5.

High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.

Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC.

Sci Transl Med. 2017 Feb 15;9(377). pii: eaaf2584. doi: 10.1126/scitranslmed.aaf2584.

6.

Two-Layer Elastographic 3-D Traction Force Microscopy.

Álvarez-González B, Zhang S, Gómez-González M, Meili R, Firtel RA, Lasheras JC, Del Álamo JC.

Sci Rep. 2017 Jan 11;7:39315. doi: 10.1038/srep39315.

7.

Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread.

Lamason RL, Bastounis E, Kafai NM, Serrano R, Del Álamo JC, Theriot JA, Welch MD.

Cell. 2016 Oct 20;167(3):670-683.e10. doi: 10.1016/j.cell.2016.09.023.

8.

Bio- chemical and physical characterizations of mesenchymal stromal cells along the time course of directed differentiation.

Chen YQ, Liu YS, Liu YA, Wu YC, Del Álamo JC, Chiou A, Lee OK.

Sci Rep. 2016 Aug 16;6:31547. doi: 10.1038/srep31547.

9.

Two-point particle tracking microrheology of nematic complex fluids.

Gómez-González M, Del Álamo JC.

Soft Matter. 2016 Jun 29;12(26):5758-79. doi: 10.1039/c6sm00769d.

PMID:
27270816
10.

High throughput physiological screening of iPSC-derived cardiomyocytes for drug development.

Del Álamo JC, Lemons D, Serrano R, Savchenko A, Cerignoli F, Bodmer R, Mercola M.

Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1717-27. doi: 10.1016/j.bbamcr.2016.03.003. Epub 2016 Mar 4. Review.

11.

Cooperative cell motility during tandem locomotion of amoeboid cells.

Bastounis E, Álvarez-González B, del Álamo JC, Lasheras JC, Firtel RA.

Mol Biol Cell. 2016 Apr 15;27(8):1262-71. doi: 10.1091/mbc.E15-12-0836. Epub 2016 Feb 24.

12.

A clinical method for mapping and quantifying blood stasis in the left ventricle.

Rossini L, Martinez-Legazpi P, Vu V, Fernández-Friera L, Pérez Del Villar C, Rodríguez-López S, Benito Y, Borja MG, Pastor-Escuredo D, Yotti R, Ledesma-Carbayo MJ, Kahn AM, Ibáñez B, Fernández-Avilés F, May-Newman K, Bermejo J, Del Álamo JC.

J Biomech. 2016 Jul 26;49(11):2152-2161. doi: 10.1016/j.jbiomech.2015.11.049. Epub 2015 Nov 30.

13.

Reply: Comments on Defining the Contribution of Diastolic Vortex Ring to Left Ventricular Filling.

Martínez-Legazpi P, Bermejo J, Benito Y, Yotti R, Pérez Del Villar C, González-Mansilla A, Barrio A, Villacorta E, Sánchez PL, Fernández-Avilés F, Del Álamo JC.

J Am Coll Cardiol. 2015 Jun 16;65(23):2574-5. doi: 10.1016/j.jacc.2015.01.068. No abstract available.

14.

Coordination of contractility, adhesion and flow in migrating Physarum amoebae.

Lewis OL, Zhang S, Guy RD, del Álamo JC.

J R Soc Interface. 2015 May 6;12(106). pii: 20141359. doi: 10.1098/rsif.2014.1359.

15.

Three-dimensional balance of cortical tension and axial contractility enables fast amoeboid migration.

Álvarez-González B, Meili R, Bastounis E, Firtel RA, Lasheras JC, Del Álamo JC.

Biophys J. 2015 Feb 17;108(4):821-832. doi: 10.1016/j.bpj.2014.11.3478.

16.

The role of elastic restoring forces in right-ventricular filling.

Pérez Del Villar C, Bermejo J, Rodríguez-Pérez D, Martínez-Legazpi P, Benito Y, Antoranz JC, Desco MM, Ortuño JE, Barrio A, Mombiela T, Yotti R, Ledesma-Carbayo MJ, Del Álamo JC, Fernández-Avilés F.

Cardiovasc Res. 2015 Jul 1;107(1):45-55. doi: 10.1093/cvr/cvv047. Epub 2015 Feb 17.

17.

3D traction stresses activate protease-dependent invasion of cancer cells.

Aung A, Seo YN, Lu S, Wang Y, Jamora C, del Álamo JC, Varghese S.

Biophys J. 2014 Dec 2;107(11):2528-37. doi: 10.1016/j.bpj.2014.07.078. Epub 2014 Dec 2.

18.

Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling.

Banerjee I, Carrion K, Serrano R, Dyo J, Sasik R, Lund S, Willems E, Aceves S, Meili R, Mercola M, Chen J, Zambon A, Hardiman G, Doherty TA, Lange S, del Álamo JC, Nigam V.

J Mol Cell Cardiol. 2015 Feb;79:133-44. doi: 10.1016/j.yjmcc.2014.11.003. Epub 2014 Nov 13.

19.

The effect of enterohemorrhagic E. coli infection on the cell mechanics of host cells.

Chen YQ, Su PT, Chen YH, Wei MT, Huang CH, Osterday K, del Álamo JC, Syu WJ, Chiou A.

PLoS One. 2014 Nov 4;9(11):e112137. doi: 10.1371/journal.pone.0112137. eCollection 2014.

20.

Cytoskeletal Mechanics Regulating Amoeboid Cell Locomotion.

Alvarez-González B, Meili R, Firtel R, Bastounis E, Del Álamo JC, Lasheras JC.

Appl Mech Rev. 2014 Jun 5;66(5). pii: 050804.

21.

Contribution of the diastolic vortex ring to left ventricular filling.

Martínez-Legazpi P, Bermejo J, Benito Y, Yotti R, Pérez Del Villar C, González-Mansilla A, Barrio A, Villacorta E, Sánchez PL, Fernández-Avilés F, del Álamo JC.

J Am Coll Cardiol. 2014 Oct 21;64(16):1711-21. doi: 10.1016/j.jacc.2014.06.1205.

22.

GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment.

Huang IH, Hsiao CT, Wu JC, Shen RF, Liu CY, Wang YK, Chen YC, Huang CM, del Álamo JC, Chang ZF, Tang MJ, Khoo KH, Kuo JC.

J Cell Sci. 2014 Oct 1;127(Pt 19):4186-200. doi: 10.1242/jcs.150227. Epub 2014 Aug 8.

23.

Both contractile axial and lateral traction force dynamics drive amoeboid cell motility.

Bastounis E, Meili R, Álvarez-González B, Francois J, del Álamo JC, Firtel RA, Lasheras JC.

J Cell Biol. 2014 Mar 17;204(6):1045-61. doi: 10.1083/jcb.201307106.

24.

Intraventricular flow patterns and stasis in the LVAD-assisted heart.

Wong K, Samaroo G, Ling I, Dembitsky W, Adamson R, del Álamo JC, May-Newman K.

J Biomech. 2014 Apr 11;47(6):1485-94. doi: 10.1016/j.jbiomech.2013.12.031. Epub 2014 Feb 1.

PMID:
24612721
25.

Intraventricular vortex properties in nonischemic dilated cardiomyopathy.

Bermejo J, Benito Y, Alhama M, Yotti R, Martínez-Legazpi P, Del Villar CP, Pérez-David E, González-Mansilla A, Santa-Marta C, Barrio A, Fernández-Avilés F, Del Álamo JC.

Am J Physiol Heart Circ Physiol. 2014 Mar 1;306(5):H718-29. doi: 10.1152/ajpheart.00697.2013. Epub 2014 Jan 10.

26.

Bicuspid aortic valves experience increased strain as compared to tricuspid aortic valves.

Szeto K, Pastuszko P, del Álamo JC, Lasheras J, Nigam V.

World J Pediatr Congenit Heart Surg. 2013 Oct;4(4):362-6. doi: 10.1177/2150135113501901.

PMID:
24327628
27.

Three-dimensional quantification of cellular traction forces and mechanosensing of thin substrata by fourier traction force microscopy.

del Álamo JC, Meili R, Álvarez-González B, Alonso-Latorre B, Bastounis E, Firtel R, Lasheras JC.

PLoS One. 2013 Sep 4;8(9):e69850. doi: 10.1371/journal.pone.0069850. eCollection 2013.

28.

In situ mechanotransduction via vinculin regulates stem cell differentiation.

Holle AW, Tang X, Vijayraghavan D, Vincent LG, Fuhrmann A, Choi YS, del Álamo JC, Engler AJ.

Stem Cells. 2013 Nov;31(11):2467-77. doi: 10.1002/stem.1490.

29.

Topology of blood transport in the human left ventricle by novel processing of Doppler echocardiography.

Hendabadi S, Bermejo J, Benito Y, Yotti R, Fernández-Avilés F, del Álamo JC, Shadden SC.

Ann Biomed Eng. 2013 Dec;41(12):2603-16. doi: 10.1007/s10439-013-0853-z. Epub 2013 Jul 2.

30.

Diastolic chamber properties of the left ventricle assessed by global fitting of pressure-volume data: improving the gold standard of diastolic function.

Bermejo J, Yotti R, Pérez del Villar C, del Álamo JC, Rodríguez-Pérez D, Martínez-Legazpi P, Benito Y, Antoranz JC, Desco MM, González-Mansilla A, Barrio A, Elízaga J, Fernández-Avilés F.

J Appl Physiol (1985). 2013 Aug 15;115(4):556-68. doi: 10.1152/japplphysiol.00363.2013. Epub 2013 Jun 6.

31.

Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength.

Vincent LG, Choi YS, Alonso-Latorre B, del Álamo JC, Engler AJ.

Biotechnol J. 2013 Apr;8(4):472-84. doi: 10.1002/biot.201200205. Epub 2013 Feb 28.

32.

Shp2 plays a crucial role in cell structural orientation and force polarity in response to matrix rigidity.

Lee HH, Lee HC, Chou CC, Hur SS, Osterday K, del Álamo JC, Lasheras JC, Chien S.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2840-5. doi: 10.1073/pnas.1222164110. Epub 2013 Jan 28.

33.

Dynamic and reversible surface topography influences cell morphology.

Kiang JD, Wen JH, del Álamo JC, Engler AJ.

J Biomed Mater Res A. 2013 Aug;101(8):2313-21. doi: 10.1002/jbm.a.34543. Epub 2013 Jan 27.

34.

Roles of cell confluency and fluid shear in 3-dimensional intracellular forces in endothelial cells.

Hur SS, del Álamo JC, Park JS, Li YS, Nguyen HA, Teng D, Wang KC, Flores L, Alonso-Latorre B, Lasheras JC, Chien S.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11110-5. doi: 10.1073/pnas.1207326109. Epub 2012 Jun 4.

35.

An Oscillatory Contractile Pole-Force Component Dominates the Traction Forces Exerted by Migrating Amoeboid Cells.

Alonso-Latorre B, Del Álamo JC, Meili R, Firtel RA, Lasheras JC.

Cell Mol Bioeng. 2011 Dec;4(4):603-615. Epub 2011 Jun 29.

36.

The SCAR/WAVE complex is necessary for proper regulation of traction stresses during amoeboid motility.

Bastounis E, Meili R, Alonso-Latorre B, del Álamo JC, Lasheras JC, Firtel RA.

Mol Biol Cell. 2011 Nov;22(21):3995-4003. doi: 10.1091/mbc.E11-03-0278. Epub 2011 Sep 7.

37.

The mechanics of the adhesive locomotion of terrestrial gastropods.

Lai JH, del Alamo JC, Rodríguez-Rodríguez J, Lasheras JC.

J Exp Biol. 2010 Nov 15;213(Pt 22):3920-33. doi: 10.1242/jeb.046706.

38.

Two-dimensional intraventricular flow mapping by digital processing conventional color-Doppler echocardiography images.

Garcia D, Del Alamo JC, Tanne D, Yotti R, Cortina C, Bertrand E, Antoranz JC, Perez-David E, Rieu R, Fernandez-Aviles F, Bermejo J.

IEEE Trans Med Imaging. 2010 Oct;29(10):1701-13. doi: 10.1109/TMI.2010.2049656. Epub 2010 Jun 17.

PMID:
20562044
39.

Resolution and uniqueness of estimated parameters of a model of thin filament regulation in solution.

Mijailovich SM, Li X, del Alamo JC, Griffiths RH, Kecman V, Geeves MA.

Comput Biol Chem. 2010 Feb;34(1):19-33. doi: 10.1016/j.compbiolchem.2009.11.002. Epub 2009 Dec 6.

PMID:
20060364
40.

Distribution of traction forces associated with shape changes during amoeboid cell migration.

Alonso-Latorre B, Meili R, Bastounis E, Del Alamo JC, Firtel R, Lasheras JC.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:3346-9. doi: 10.1109/IEMBS.2009.5333191.

PMID:
19964075
41.

Myosin II is essential for the spatiotemporal organization of traction forces during cell motility.

Meili R, Alonso-Latorre B, del Alamo JC, Firtel RA, Lasheras JC.

Mol Biol Cell. 2010 Feb 1;21(3):405-17. doi: 10.1091/mbc.E09-08-0703. Epub 2009 Dec 2.

42.

Recent advances in the application of computational mechanics to the diagnosis and treatment of cardiovascular disease.

Del Alamo JC, Marsden AL, Lasheras JC.

Rev Esp Cardiol. 2009 Jul;62(7):781-805. English, Spanish.

43.

Anisotropic rheology and directional mechanotransduction in vascular endothelial cells.

del Alamo JC, Norwich GN, Li YS, Lasheras JC, Chien S.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15411-6. doi: 10.1073/pnas.0804573105.

44.

Spatio-temporal analysis of eukaryotic cell motility by improved force cytometry.

Del Alamo JC, Meili R, Alonso-Latorre B, Rodríguez-Rodríguez J, Aliseda A, Firtel RA, Lasheras JC.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13343-8. Epub 2007 Aug 7.

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