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Items: 1 to 50 of 68

1.

Formative research to inform development of a new diagnostic for soil-transmitted helminths: Going beyond the laboratory to ensure access to a needed product.

Storey HL, Agarwal N, Cantera J, Golden A, Gallo K, Herrick T, Belizario V Jr, Kihara J, Mwandawiro C, Cadwallader B, de Los Santos T.

PLoS Negl Trop Dis. 2019 May 31;13(5):e0007372. doi: 10.1371/journal.pntd.0007372. eCollection 2019 May.

2.

The VP1 G-H loop hypervariable epitope contributes to protective immunity against Foot and Mouth Disease Virus in swine.

Fernandez-Sainz I, Gavitt TD, Koster M, Ramirez-Medina E, Rodriguez YY, Wu P, Silbart LK, de Los Santos T, Szczepanek SM.

Vaccine. 2019 Jun 6;37(26):3435-3442. doi: 10.1016/j.vaccine.2019.05.019. Epub 2019 May 10.

PMID:
31085001
3.

Predictive Value of Ov16 Antibody Prevalence in Different Subpopulations for Elimination of African Onchocerciasis.

Coffeng LE, Stolk WA, Golden A, de Los Santos T, Domingo GJ, de Vlas SJ.

Am J Epidemiol. 2019 Sep 1;188(9):1723-1732. doi: 10.1093/aje/kwz109.

4.

Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80.

Chen X, Gaglione R, Leong T, Bednor L, de Los Santos T, Luk E, Airola M, Hollingsworth NM.

PLoS Genet. 2018 Nov 29;14(11):e1007832. doi: 10.1371/journal.pgen.1007832. eCollection 2018 Nov.

5.

The Different Tactics of Foot-and-Mouth Disease Virus to Evade Innate Immunity.

Medina GN, Segundo FD, Stenfeldt C, Arzt J, de Los Santos T.

Front Microbiol. 2018 Nov 12;9:2644. doi: 10.3389/fmicb.2018.02644. eCollection 2018. Review.

6.

Foot-and-Mouth Disease Virus Leader Protease Cleaves G3BP1 and G3BP2 and Inhibits Stress Granule Formation.

Visser LJ, Medina GN, Rabouw HH, de Groot RJ, Langereis MA, de Los Santos T, van Kuppeveld FJM.

J Virol. 2019 Jan 4;93(2). pii: e00922-18. doi: 10.1128/JVI.00922-18. Print 2019 Jan 15.

7.

The need for improved vaccines against foot-and-mouth disease.

de Los Santos T, Diaz-San Segundo F, Rodriguez LL.

Curr Opin Virol. 2018 Apr;29:16-25. doi: 10.1016/j.coviro.2018.02.005. Epub 2018 Mar 12. Review.

PMID:
29544088
8.

Feasibility of utilizing the SD BIOLINE Onchocerciasis IgG4 rapid test in onchocerciasis surveillance in Senegal.

Dieye Y, Storey HL, Barrett KL, Gerth-Guyette E, Di Giorgio L, Golden A, Faulx D, Kalnoky M, Ndiaye MKN, Sy N, Mané M, Faye B, Sarr M, Dioukhane EM, Peck RB, Guinot P, de Los Santos T.

PLoS Negl Trop Dis. 2017 Oct 3;11(10):e0005884. doi: 10.1371/journal.pntd.0005884. eCollection 2017 Oct.

9.

Foot-and-mouth disease virus 5'-terminal S fragment is required for replication and modulation of the innate immune response in host cells.

Kloc A, Diaz-San Segundo F, Schafer EA, Rai DK, Kenney M, de Los Santos T, Rieder E.

Virology. 2017 Dec;512:132-143. doi: 10.1016/j.virol.2017.08.036.

10.

Recombinant human adenovirus-5 expressing capsid proteins of Indian vaccine strains of foot-and-mouth disease virus elicits effective antibody response in cattle.

Sreenivasa BP, Mohapatra JK, Pauszek SJ, Koster M, Dhanya VC, Tamil Selvan RP, Hosamani M, Saravanan P, Basagoudanavar SH, de Los Santos T, Venkataramanan R, Rodriguez LL, Grubman MJ.

Vet Microbiol. 2017 May;203:196-201. doi: 10.1016/j.vetmic.2017.03.019. Epub 2017 Mar 18.

PMID:
28619144
11.

Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity.

Rai DK, Diaz-San Segundo F, Campagnola G, Keith A, Schafer EA, Kloc A, de Los Santos T, Peersen O, Rieder E.

J Virol. 2017 Jul 12;91(15). pii: e00081-17. doi: 10.1128/JVI.00081-17. Print 2017 Aug 1.

12.

Interaction between FMDV Lpro and transcription factor ADNP is required for optimal viral replication.

Medina GN, Knudsen GM, Greninger AL, Kloc A, Díaz-San Segundo F, Rieder E, Grubman MJ, DeRisi JL, de Los Santos T.

Virology. 2017 May;505:12-22. doi: 10.1016/j.virol.2017.02.010. Epub 2017 Feb 17.

13.

Host microRNA-203a Is antagonistic to the progression of foot-and-mouth disease virus infection.

Gutkoska J, LaRocco M, Ramirez-Medina E, de Los Santos T, Lawrence P.

Virology. 2017 Apr;504:52-62. doi: 10.1016/j.virol.2017.01.019. Epub 2017 Jan 31.

14.

Modelling Anti-Ov16 IgG4 Antibody Prevalence as an Indicator for Evaluation and Decision Making in Onchocerciasis Elimination Programmes.

Lont YL, Coffeng LE, de Vlas SJ, Golden A, de Los Santos T, Domingo GJ, Stolk WA.

PLoS Negl Trop Dis. 2017 Jan 23;11(1):e0005314. doi: 10.1371/journal.pntd.0005314. eCollection 2017 Jan.

15.

Foot-and-mouth disease vaccines.

Diaz-San Segundo F, Medina GN, Stenfeldt C, Arzt J, de Los Santos T.

Vet Microbiol. 2017 Jul;206:102-112. doi: 10.1016/j.vetmic.2016.12.018. Epub 2016 Dec 19. Review.

PMID:
28040311
16.

Adenovirus-vectored foot-and-mouth disease vaccine confers early and full protection against FMDV O1 Manisa in swine.

Fernandez-Sainz I, Medina GN, Ramirez-Medina E, Koster MJ, Grubman MJ, de Los Santos T.

Virology. 2017 Feb;502:123-132. doi: 10.1016/j.virol.2016.12.021. Epub 2016 Dec 28.

17.

Diagnostic Tests to Support Late-Stage Control Programs for Schistosomiasis and Soil-Transmitted Helminthiases.

Hawkins KR, Cantera JL, Storey HL, Leader BT, de Los Santos T.

PLoS Negl Trop Dis. 2016 Dec 22;10(12):e0004985. doi: 10.1371/journal.pntd.0004985. eCollection 2016 Dec. Review.

18.

Combination of Adt-O1Manisa and Ad5-boIFNλ3 induces early protective immunity against foot-and-mouth disease in cattle.

Diaz-San Segundo F, Montiel NA, Sturza DF, Perez-Martin E, Hickman D, Ramirez-Medina E, Grubman MJ, de Los Santos T.

Virology. 2016 Dec;499:340-349. doi: 10.1016/j.virol.2016.09.027. Epub 2016 Oct 12.

19.

Constitutively Active IRF7/IRF3 Fusion Protein Completely Protects Swine against Foot-and-Mouth Disease.

Ramírez-Carvajal L, Diaz-San Segundo F, Ramirez-Medina E, Rodríguez LL, de Los Santos T.

J Virol. 2016 Sep 12;90(19):8809-21. doi: 10.1128/JVI.00800-16. Print 2016 Oct 1.

20.

Analysis of age-dependent trends in Ov16 IgG4 seroprevalence to onchocerciasis.

Golden A, Faulx D, Kalnoky M, Stevens E, Yokobe L, Peck R, Karabou P, Banla M, Rao R, Adade K, Gantin RG, Komlan K, Soboslay PT, de Los Santos T, Domingo GJ.

Parasit Vectors. 2016 Jun 13;9(1):338. doi: 10.1186/s13071-016-1623-1.

21.

The Pathogenesis of Foot-and-Mouth Disease in Pigs.

Stenfeldt C, Diaz-San Segundo F, de Los Santos T, Rodriguez LL, Arzt J.

Front Vet Sci. 2016 May 23;3:41. doi: 10.3389/fvets.2016.00041. eCollection 2016. Review.

22.

Novel 6xHis tagged foot-and-mouth disease virus vaccine bound to nanolipoprotein adjuvant via metal ions provides antigenic distinction and effective protective immunity.

Rai DK, Segundo FD, Schafer E, Burrage TG, Rodriguez LL, de Los Santos T, Hoeprich PD, Rieder E.

Virology. 2016 Aug;495:136-47. doi: 10.1016/j.virol.2016.04.027. Epub 2016 May 20.

23.

A Recombinant Positive Control for Serology Diagnostic Tests Supporting Elimination of Onchocerca volvulus.

Golden A, Stevens EJ, Yokobe L, Faulx D, Kalnoky M, Peck R, Valdez M, Steel C, Karabou P, Banla M, Soboslay PT, Adade K, Tekle AH, Cama VA, Fischer PU, Nutman TB, Unnasch TR, de los Santos T, Domingo GJ.

PLoS Negl Trop Dis. 2016 Jan 8;10(1):e0004292. doi: 10.1371/journal.pntd.0004292. eCollection 2016 Jan.

24.

Evaluation of a Fiber-Modified Adenovirus Vector Vaccine against Foot-and-Mouth Disease in Cattle.

Medina GN, Montiel N, Diaz-San Segundo F, Sturza D, Ramirez-Medina E, Grubman MJ, de los Santos T.

Clin Vaccine Immunol. 2015 Nov 25;23(2):125-36. doi: 10.1128/CVI.00426-15.

25.

Depletion of elongation initiation factor 4E binding proteins by CRISPR/Cas9 enhances the antiviral response in porcine cells.

Ramírez-Carvajal L, Singh N, de los Santos T, Rodríguez LL, Long CR.

Antiviral Res. 2016 Jan;125:8-13. doi: 10.1016/j.antiviral.2015.11.002. Epub 2015 Nov 22.

PMID:
26592975
26.

Synonymous Deoptimization of Foot-and-Mouth Disease Virus Causes Attenuation In Vivo while Inducing a Strong Neutralizing Antibody Response.

Diaz-San Segundo F, Medina GN, Ramirez-Medina E, Velazquez-Salinas L, Koster M, Grubman MJ, de los Santos T.

J Virol. 2015 Nov 18;90(3):1298-310. doi: 10.1128/JVI.02167-15. Print 2016 Feb 1.

27.

A Meta-Analysis of Typhoid Diagnostic Accuracy Studies: A Recommendation to Adopt a Standardized Composite Reference.

Storey HL, Huang Y, Crudder C, Golden A, de los Santos T, Hawkins K.

PLoS One. 2015 Nov 13;10(11):e0142364. doi: 10.1371/journal.pone.0142364. eCollection 2015.

28.

Inhibition of EHMT2 Induces a Robust Antiviral Response Against Foot-and-Mouth Disease and Vesicular Stomatitis Virus Infections in Bovine Cells.

Singh N, Ramĩrez-Carvajal L, de Los Santos T, Golding MC, Long CR.

J Interferon Cytokine Res. 2016 Jan;36(1):37-47. doi: 10.1089/jir.2015.0006. Epub 2015 Sep 29.

29.

Rapid Point-of-Contact Tool for Mapping and Integrated Surveillance of Wuchereria bancrofti and Onchocerca volvulus Infection.

Steel C, Golden A, Stevens E, Yokobe L, Domingo GJ, de los Santos T, Nutman TB.

Clin Vaccine Immunol. 2015 Aug;22(8):896-901. doi: 10.1128/CVI.00227-15. Epub 2015 May 27.

30.

Treatment with interferon-alpha delays disease in swine infected with a highly virulent CSFV strain.

Fernandez-Sainz I, Ramanathan P, O'Donnell V, Diaz-San Segundo F, Velazquez-Salinas L, Sturza DF, Zhu J, de los Santos T, Borca MV.

Virology. 2015 Sep;483:284-90. doi: 10.1016/j.virol.2015.04.024. Epub 2015 May 21.

31.

Poly ICLC increases the potency of a replication-defective human adenovirus vectored foot-and-mouth disease vaccine.

Diaz-San Segundo F, Dias CC, Moraes MP, Weiss M, Perez-Martin E, Salazar AM, Grubman MJ, de Los Santos T.

Virology. 2014 Nov;468-470:283-292. doi: 10.1016/j.virol.2014.08.012. Epub 2014 Sep 12.

32.

Expression of porcine fusion protein IRF7/3(5D) efficiently controls foot-and-mouth disease virus replication.

Ramírez-Carvajal L, Díaz-San Segundo F, Hickman D, Long CR, Zhu J, Rodríguez LL, de los Santos T.

J Virol. 2014 Oct;88(19):11140-53. doi: 10.1128/JVI.00372-14. Epub 2014 Jul 16.

33.

Type III interferon protects swine against foot-and-mouth disease.

Perez-Martin E, Diaz-San Segundo F, Weiss M, Sturza DF, Dias CC, Ramirez-Medina E, Grubman MJ, de los Santos T.

J Interferon Cytokine Res. 2014 Oct;34(10):810-21. doi: 10.1089/jir.2013.0112. Epub 2014 Apr 30.

PMID:
24786495
34.

Foot-and-mouth disease virus virulence in cattle is co-determined by viral replication dynamics and route of infection.

Arzt J, Pacheco JM, Smoliga GR, Tucker MT, Bishop E, Pauszek SJ, Hartwig EJ, de los Santos T, Rodriguez LL.

Virology. 2014 Mar;452-453:12-22. doi: 10.1016/j.virol.2014.01.001. Epub 2014 Jan 25.

35.

Extended result reading window in lateral flow tests detecting exposure to Onchocerca volvulus: a new technology to improve epidemiological surveillance tools.

Golden A, Steel C, Yokobe L, Jackson E, Barney R, Kubofcik J, Peck R, Unnasch TR, Nutman TB, de los Santos T, Domingo GJ.

PLoS One. 2013 Jul 23;8(7):e69231. doi: 10.1371/journal.pone.0069231. Print 2013.

36.

Rapid Wuchereria bancrofti-specific antigen Wb123-based IgG4 immunoassays as tools for surveillance following mass drug administration programs on lymphatic filariasis.

Steel C, Golden A, Kubofcik J, LaRue N, de Los Santos T, Domingo GJ, Nutman TB.

Clin Vaccine Immunol. 2013 Aug;20(8):1155-61. doi: 10.1128/CVI.00252-13. Epub 2013 Jun 5.

37.

Venezuelan equine encephalitis replicon particles can induce rapid protection against foot-and-mouth disease virus.

Diaz-San Segundo F, Dias CC, Moraes MP, Weiss M, Perez-Martin E, Owens G, Custer M, Kamrud K, de los Santos T, Grubman MJ.

J Virol. 2013 May;87(10):5447-60. doi: 10.1128/JVI.03462-12. Epub 2013 Mar 6.

38.

Novel antiviral therapeutics to control foot-and-mouth disease.

Dias CC, Moraes MP, Weiss M, Diaz-San Segundo F, Perez-Martin E, Salazar AM, de los Santos T, Grubman MJ.

J Interferon Cytokine Res. 2012 Oct;32(10):462-73. doi: 10.1089/jir.2012.0012. Epub 2012 Aug 27.

PMID:
22924938
39.

The Value of Clinical Needs Assessments for Point-of-Care Diagnostics.

Weigl BH, Gaydos CA, Kost G, Beyette FR Jr, Sabourin S, Rompalo A, de Los Santos T, McMullan JT, Haller J.

Point Care. 2012 Jun;11(2):108-113.

40.

Bovine type III interferon significantly delays and reduces the severity of foot-and-mouth disease in cattle.

Perez-Martin E, Weiss M, Diaz-San Segundo F, Pacheco JM, Arzt J, Grubman MJ, de los Santos T.

J Virol. 2012 Apr;86(8):4477-87. doi: 10.1128/JVI.06683-11. Epub 2012 Feb 1.

41.

Management of the HIV epidemic in Nicaragua: the need to improve information systems and access to affordable diagnostics.

Espinoza H, Sequeira M, Domingo G, Amador JJ, Quintanilla M, de los Santos T.

Bull World Health Organ. 2011 Aug 1;89(8):619-20. doi: 10.2471/BLT.11.086124. No abstract available.

42.

Evidence of activation and suppression during the early immune response to foot-and-mouth disease virus.

Golde WT, de Los Santos T, Robinson L, Grubman MJ, Sevilla N, Summerfield A, Charleston B.

Transbound Emerg Dis. 2011 Aug;58(4):283-90. doi: 10.1111/j.1865-1682.2011.01223.x. Epub 2011 Apr 18. Review.

PMID:
21501424
43.

Antiviral activity of bovine type III interferon against foot-and-mouth disease virus.

Díaz-San Segundo F, Weiss M, Perez-Martín E, Koster MJ, Zhu J, Grubman MJ, de los Santos T.

Virology. 2011 May 10;413(2):283-92. doi: 10.1016/j.virol.2011.02.023. Epub 2011 Mar 24.

44.

Cost analysis of centralized viral load testing for antiretroviral therapy monitoring in Nicaragua, a low-HIV prevalence, low-resource setting.

Gerlach J, Sequeira M, Alvarado V, Cerpas C, Balmaseda A, Gonzalez A, de Los Santos T, Levin CE, Amador JJ, Domingo GJ.

J Int AIDS Soc. 2010 Nov 5;13:43. doi: 10.1186/1758-2652-13-43.

45.

Porcine type I interferon rapidly protects swine against challenge with multiple serotypes of foot-and-mouth disease virus.

Dias CC, Moraes MP, Segundo FD, de los Santos T, Grubman MJ.

J Interferon Cytokine Res. 2011 Feb;31(2):227-36. doi: 10.1089/jir.2010.0055. Epub 2010 Sep 28.

PMID:
20874428
46.

Introduction of tag epitopes in the inter-AUG region of foot and mouth disease virus: effect on the L protein.

Piccone ME, Diaz-San Segundo F, Kramer E, Rodriguez LL, de los Santos T.

Virus Res. 2011 Jan;155(1):91-7. doi: 10.1016/j.virusres.2010.09.004. Epub 2010 Sep 16.

PMID:
20849893
47.

Differential gene expression in bovine cells infected with wild type and leaderless foot-and-mouth disease virus.

Zhu J, Weiss M, Grubman MJ, de los Santos T.

Virology. 2010 Aug 15;404(1):32-40. doi: 10.1016/j.virol.2010.04.021. Epub 2010 May 23.

48.

Interferon-induced protection against foot-and-mouth disease virus infection correlates with enhanced tissue-specific innate immune cell infiltration and interferon-stimulated gene expression.

Diaz-San Segundo F, Moraes MP, de Los Santos T, Dias CC, Grubman MJ.

J Virol. 2010 Feb;84(4):2063-77. doi: 10.1128/JVI.01874-09. Epub 2009 Dec 2.

49.

Simplicity of use: a critical feature for widespread adoption of diagnostic technologies in low-resource settings.

Weigl BH, Boyle DS, de los Santos T, Peck RB, Steele MS.

Expert Rev Med Devices. 2009 Sep;6(5):461-4. doi: 10.1586/erd.09.31. No abstract available.

PMID:
19751117
50.

A conserved domain in the leader proteinase of foot-and-mouth disease virus is required for proper subcellular localization and function.

de los Santos T, Segundo FD, Zhu J, Koster M, Dias CC, Grubman MJ.

J Virol. 2009 Feb;83(4):1800-10. doi: 10.1128/JVI.02112-08. Epub 2008 Dec 3.

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