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Items: 46

1.

High-Density Lipoprotein Proteomic Composition, and not Efflux Capacity, Reflects Differential Modulation of Reverse Cholesterol Transport by Saturated and Monounsaturated Fat Diets.

O'Reilly M, Dillon E, Guo W, Finucane O, McMorrow A, Murphy A, Lyons C, Jones D, Ryan M, Gibney M, Gibney E, Brennan L, de la Llera Moya M, Reilly MP, Roche HM, McGillicuddy FC.

Circulation. 2016 May 10;133(19):1838-50. doi: 10.1161/CIRCULATIONAHA.115.020278. Epub 2016 Apr 14.

2.

Importance of evaluating cell cholesterol influx with efflux in determining the impact of human serum on cholesterol metabolism and atherosclerosis.

Weibel GL, Drazul-Schrader D, Shivers DK, Wade AN, Rothblat GH, Reilly MP, de la Llera-Moya M.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):17-25. doi: 10.1161/ATVBAHA.113.302437. Epub 2013 Nov 7.

3.

Serum albumin acts as a shuttle to enhance cholesterol efflux from cells.

Sankaranarayanan S, de la Llera-Moya M, Drazul-Schrader D, Phillips MC, Kellner-Weibel G, Rothblat GH.

J Lipid Res. 2013 Mar;54(3):671-6. doi: 10.1194/jlr.M031336. Epub 2013 Jan 3.

4.

Inflammation modulates human HDL composition and function in vivo.

de la Llera Moya M, McGillicuddy FC, Hinkle CC, Byrne M, Joshi MR, Nguyen V, Tabita-Martinez J, Wolfe ML, Badellino K, Pruscino L, Mehta NN, Asztalos BF, Reilly MP.

Atherosclerosis. 2012 Jun;222(2):390-4. doi: 10.1016/j.atherosclerosis.2012.02.032. Epub 2012 Feb 28.

5.

The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice.

Lagor WR, Fields DW, Khetarpal SA, Kumaravel A, Lin W, Weintraub N, Wu K, Hamm-Alvarez SF, Drazul-Schrader D, de la Llera-Moya M, Rothblat GH, Rader DJ.

PLoS One. 2012;7(2):e31616. doi: 10.1371/journal.pone.0031616. Epub 2012 Feb 20.

6.

A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol.

Sankaranarayanan S, Kellner-Weibel G, de la Llera-Moya M, Phillips MC, Asztalos BF, Bittman R, Rothblat GH.

J Lipid Res. 2011 Dec;52(12):2332-40. doi: 10.1194/jlr.D018051. Epub 2011 Sep 27.

7.

Disruption of the murine procollagen C-proteinase enhancer 2 gene causes accumulation of pro-apoA-I and increased HDL levels.

Francone OL, Ishida BY, de la Llera-Moya M, Royer L, Happe C, Zhu J, Chalkey RJ, Schaefer P, Cox C, Burlingame A, Kane JP, Rothblat GH.

J Lipid Res. 2011 Nov;52(11):1974-83. doi: 10.1194/jlr.M016527. Epub 2011 Jul 19.

8.

Update on HDL receptors and cellular cholesterol transport.

Kellner-Weibel G, de la Llera-Moya M.

Curr Atheroscler Rep. 2011 Jun;13(3):233-41. doi: 10.1007/s11883-011-0169-0. Review.

PMID:
21302003
9.

Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis.

Khera AV, Cuchel M, de la Llera-Moya M, Rodrigues A, Burke MF, Jafri K, French BC, Phillips JA, Mucksavage ML, Wilensky RL, Mohler ER, Rothblat GH, Rader DJ.

N Engl J Med. 2011 Jan 13;364(2):127-35. doi: 10.1056/NEJMoa1001689.

10.

Influence of apolipoprotein A-I domain structure on macrophage reverse cholesterol transport in mice.

Alexander ET, Vedhachalam C, Sankaranarayanan S, de la Llera-Moya M, Rothblat GH, Rader DJ, Phillips MC.

Arterioscler Thromb Vasc Biol. 2011 Feb;31(2):320-7. doi: 10.1161/ATVBAHA.110.216226. Epub 2010 Nov 11.

11.

Importance of macrophage cholesterol content on the flux of cholesterol mass.

Sankaranarayanan S, de la Llera-Moya M, Drazul-Schrader D, Asztalos BF, Weibel GL, Rothblat GH.

J Lipid Res. 2010 Nov;51(11):3243-9. doi: 10.1194/jlr.M008441. Epub 2010 Aug 16.

12.

Suppression of human prostate tumor growth by a unique prostate-specific monoclonal antibody F77 targeting a glycolipid marker.

Zhang G, Zhang H, Wang Q, Lal P, Carroll AM, de la Llera-Moya M, Xu X, Greene MI.

Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):732-7. doi: 10.1073/pnas.0911397107. Epub 2009 Dec 18.

13.

The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages.

de la Llera-Moya M, Drazul-Schrader D, Asztalos BF, Cuchel M, Rader DJ, Rothblat GH.

Arterioscler Thromb Vasc Biol. 2010 Apr;30(4):796-801. doi: 10.1161/ATVBAHA.109.199158. Epub 2010 Jan 14.

14.

Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages.

Cuchel M, Lund-Katz S, de la Llera-Moya M, Millar JS, Chang D, Fuki I, Rothblat GH, Phillips MC, Rader DJ.

Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):526-32. doi: 10.1161/ATVBAHA.109.196105. Epub 2009 Dec 17.

15.

Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano.

Alexander ET, Weibel GL, Joshi MR, Vedhachalam C, de la Llera-Moya M, Rothblat GH, Phillips MC, Rader DJ.

Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1496-501. doi: 10.1161/ATVBAHA.109.191379. Epub 2009 Aug 6.

16.

Inflammation impairs reverse cholesterol transport in vivo.

McGillicuddy FC, de la Llera Moya M, Hinkle CC, Joshi MR, Chiquoine EH, Billheimer JT, Rothblat GH, Reilly MP.

Circulation. 2009 Mar 3;119(8):1135-45. doi: 10.1161/CIRCULATIONAHA.108.810721. Epub 2009 Feb 16.

17.

Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo.

Sacks FM, Rudel LL, Conner A, Akeefe H, Kostner G, Baki T, Rothblat G, de la Llera-Moya M, Asztalos B, Perlman T, Zheng C, Alaupovic P, Maltais JA, Brewer HB.

J Lipid Res. 2009 May;50(5):894-907. doi: 10.1194/jlr.M800622-JLR200. Epub 2009 Jan 14.

18.

Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo.

Lagor WR, Brown RJ, Toh SA, Millar JS, Fuki IV, de la Llera-Moya M, Yuen T, Rothblat G, Billheimer JT, Rader DJ.

Arterioscler Thromb Vasc Biol. 2009 Jan;29(1):40-6. doi: 10.1161/ATVBAHA.108.177105. Epub 2008 Nov 13.

19.

Effects of niacin and Niaspan on HDL lipoprotein cellular SR-BI-mediated cholesterol efflux.

Morgan JM, de la Llera-Moya M, Capuzzi DM.

J Clin Lipidol. 2007 Dec;1(6):614-9. doi: 10.1016/j.jacl.2007.09.003. Epub 2007 Oct 5.

PMID:
21291703
20.

Effects of amino acid substitutions at glycine 420 on SR-BI cholesterol transport function.

Parathath S, Darlington YF, de la Llera Moya M, Drazul-Schrader D, Williams DL, Phillips MC, Rothblat GH, Connelly MA.

J Lipid Res. 2007 Jun;48(6):1386-95. Epub 2007 Mar 19.

21.

Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux.

Asztalos BF, de la Llera-Moya M, Dallal GE, Horvath KV, Schaefer EJ, Rothblat GH.

J Lipid Res. 2005 Oct;46(10):2246-53. Epub 2005 Aug 1.

22.

Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-BI mediate HDL-initiated signaling.

Assanasen C, Mineo C, Seetharam D, Yuhanna IS, Marcel YL, Connelly MA, Williams DL, de la Llera-Moya M, Shaul PW, Silver DL.

J Clin Invest. 2005 Apr;115(4):969-77. Epub 2005 Mar 24.

23.

Changes in plasma membrane properties and phosphatidylcholine subspecies of insect Sf9 cells due to expression of scavenger receptor class B, type I, and CD36.

Parathath S, Connelly MA, Rieger RA, Klein SM, Abumrad NA, De La Llera-Moya M, Iden CR, Rothblat GH, Williams DL.

J Biol Chem. 2004 Oct 1;279(40):41310-8. Epub 2004 Jul 27.

24.

Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure.

Thuahnai ST, Lund-Katz S, Dhanasekaran P, de la Llera-Moya M, Connelly MA, Williams DL, Rothblat GH, Phillips MC.

J Biol Chem. 2004 Mar 26;279(13):12448-55. Epub 2004 Jan 12.

25.

Separation of lipid transport functions by mutations in the extracellular domain of scavenger receptor class B, type I.

Connelly MA, De La Llera-Moya M, Peng Y, Drazul-Schrader D, Rothblat GH, Williams DL.

J Biol Chem. 2003 Jul 11;278(28):25773-82. Epub 2003 May 2.

26.

Importance of different pathways of cellular cholesterol efflux.

Yancey PG, Bortnick AE, Kellner-Weibel G, de la Llera-Moya M, Phillips MC, Rothblat GH.

Arterioscler Thromb Vasc Biol. 2003 May 1;23(5):712-9. Epub 2003 Jan 23. Review.

PMID:
12615688
27.

Cellular cholesterol flux studies: methodological considerations.

Rothblat GH, de la Llera-Moya M, Favari E, Yancey PG, Kellner-Weibel G.

Atherosclerosis. 2002 Jul;163(1):1-8.

PMID:
12048116
28.

Scavenger receptor class B type I affects cholesterol homeostasis by magnifying cholesterol flux between cells and HDL.

de La Llera-Moya M, Connelly MA, Drazul D, Klein SM, Favari E, Yancey PG, Williams DL, Rothblat GH.

J Lipid Res. 2001 Dec;42(12):1969-78.

29.

Analysis of chimeric receptors shows that multiple distinct functional activities of scavenger receptor, class B, type I (SR-BI), are localized to the extracellular receptor domain.

Connelly MA, de la Llera-Moya M, Monzo P, Yancey PG, Drazul D, Stoudt G, Fournier N, Klein SM, Rothblat GH, Williams DL.

Biochemistry. 2001 May 1;40(17):5249-59.

PMID:
11318648
30.

High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI.

Yancey PG, de la Llera-Moya M, Swarnakar S, Monzo P, Klein SM, Connelly MA, Johnson WJ, Williams DL, Rothblat GH.

J Biol Chem. 2000 Nov 24;275(47):36596-604.

31.

Binding and cross-linking studies show that scavenger receptor BI interacts with multiple sites in apolipoprotein A-I and identify the class A amphipathic alpha-helix as a recognition motif.

Williams DL, de La Llera-Moya M, Thuahnai ST, Lund-Katz S, Connelly MA, Azhar S, Anantharamaiah GM, Phillips MC.

J Biol Chem. 2000 Jun 23;275(25):18897-904.

32.

Expression of scavenger receptor BI in COS-7 cells alters cholesterol content and distribution.

Kellner-Weibel G, de La Llera-Moya M, Connelly MA, Stoudt G, Christian AE, Haynes MP, Williams DL, Rothblat GH.

Biochemistry. 2000 Jan 11;39(1):221-9.

PMID:
10625497
33.
34.

Scavenger receptor BI and cholesterol trafficking.

Williams DL, Connelly MA, Temel RE, Swarnakar S, Phillips MC, de la Llera-Moya M, Rothblat GH.

Curr Opin Lipidol. 1999 Aug;10(4):329-39. Review.

PMID:
10482136
35.

Cell cholesterol efflux: integration of old and new observations provides new insights.

Rothblat GH, de la Llera-Moya M, Atger V, Kellner-Weibel G, Williams DL, Phillips MC.

J Lipid Res. 1999 May;40(5):781-96. Review.

36.

Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface.

de la Llera-Moya M, Rothblat GH, Connelly MA, Kellner-Weibel G, Sakr SW, Phillips MC, Williams DL.

J Lipid Res. 1999 Mar;40(3):575-80.

37.

Dietary modification of high density lipoprotein phospholipid and influence on cellular cholesterol efflux.

Gillotte KL, Lund-Katz S, de la Llera-Moya M, Parks JS, Rudel LL, Rothblat GH, Phillips MC.

J Lipid Res. 1998 Oct;39(10):2065-75.

38.

Scavenger receptor class B type I as a mediator of cellular cholesterol efflux to lipoproteins and phospholipid acceptors.

Jian B, de la Llera-Moya M, Ji Y, Wang N, Phillips MC, Swaney JB, Tall AR, Rothblat GH.

J Biol Chem. 1998 Mar 6;273(10):5599-606.

39.

HDL phospholipid content and composition as a major factor determining cholesterol efflux capacity from Fu5AH cells to human serum.

Fournier N, Paul JL, Atger V, Cogny A, Soni T, de la Llera-Moya M, Rothblat G, Moatti N.

Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):2685-91.

PMID:
9409243
40.

Modification of the cholesterol efflux properties of human serum by enrichment with phospholipid.

Jian B, de la Llera-Moya M, Royer L, Rothblat G, Francone O, Swaney JB.

J Lipid Res. 1997 Apr;38(4):734-44.

41.

Cyclodextrins as catalysts for the removal of cholesterol from macrophage foam cells.

Atger VM, de la Llera Moya M, Stoudt GW, Rodrigueza WV, Phillips MC, Rothblat GH.

J Clin Invest. 1997 Feb 15;99(4):773-80.

42.

Role of HDL phospholipid in efflux of cell cholesterol to whole serum: studies with human apoA-I transgenic rats.

Fournier N, de la Llera Moya M, Burkey BF, Swaney JB, Paterniti J Jr, Moatti N, Atger V, Rothblat GH.

J Lipid Res. 1996 Aug;37(8):1704-11.

43.

Cholesterol efflux potential of sera from mice expressing human cholesteryl ester transfer protein and/or human apolipoprotein AI.

Atger V, de la Llera Moya M, Bamberger M, Francone O, Cosgrove P, Tall A, Walsh A, Moatti N, Rothblat G.

J Clin Invest. 1995 Dec;96(6):2613-22.

44.
45.

A cell culture system for screening human serum for ability to promote cellular cholesterol efflux. Relations between serum components and efflux, esterification, and transfer.

de la Llera Moya M, Atger V, Paul JL, Fournier N, Moatti N, Giral P, Friday KE, Rothblat G.

Arterioscler Thromb. 1994 Jul;14(7):1056-65.

PMID:
8018660
46.

Etoposide treatment suppresses atherosclerotic plaque development in cholesterol-fed rabbits.

de la Llera-Moya M, Rothblat GH, Glick JM, England JM.

Arterioscler Thromb. 1992 Nov;12(11):1363-70.

PMID:
1420096

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