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The Vascular Consequences of Metabolic Syndrome: Rodent Models, Endothelial Dysfunction, and Current Therapies.

Tran V, De Silva TM, Sobey CG, Lim K, Drummond GR, Vinh A, Jelinic M.

Front Pharmacol. 2020 Mar 4;11:148. doi: 10.3389/fphar.2020.00148. eCollection 2020. Review.


SpineCloud: image analytics for predictive modeling of spine surgery outcomes.

De Silva T, Vedula SS, Perdomo-Pantoja A, Vijayan R, Doerr SA, Uneri A, Han R, Ketcha MD, Skolasky RL, Witham T, Theodore N, Siewerdsen JH.

J Med Imaging (Bellingham). 2020 May;7(3):031502. doi: 10.1117/1.JMI.7.3.031502. Epub 2020 Feb 18.


A mobile isocentric C-arm for intraoperative cone-beam CT: Technical assessment of dose and 3D imaging performance.

Sheth NM, De Silva T, Uneri A, Ketcha M, Han R, Vijayan R, Osgood GM, Siewerdsen JH.

Med Phys. 2020 Mar;47(3):958-974. doi: 10.1002/mp.13983. Epub 2020 Jan 6.


Learning-based deformable image registration: effect of statistical mismatch between train and test images.

Ketcha MD, De Silva T, Han R, Uneri A, Vogt S, Kleinszig G, Siewerdsen JH.

J Med Imaging (Bellingham). 2019 Oct;6(4):044008. doi: 10.1117/1.JMI.6.4.044008. Epub 2019 Dec 17.


Respiratory syncytial, parainfluenza and influenza virus infection in young children with acute lower respiratory infection in rural Gambia.

Mackenzie GA, Vilane A, Salaudeen R, Hogerwerf L, van den Brink S, Wijsman LA, Overduin P, Janssens TKS, de Silva TI, van der Sande MAB, Kampmann B, Meijer A.

Sci Rep. 2019 Nov 29;9(1):17965. doi: 10.1038/s41598-019-54059-4.


Pyrenylpyridines: Sky-Blue Emitters for Organic Light-Emitting Diodes.

De Silva TPD, Youm SG, Tamas GG, Yang B, Wang CH, Fronczek FR, Sahasrabudhe G, Sterling S, Quarels RD, Chhotaray PK, Nesterov EE, Warner IM.

ACS Omega. 2019 Oct 3;4(16):16867-16877. doi: 10.1021/acsomega.9b01948. eCollection 2019 Oct 15.


Contributions of Aging to Cerebral Small Vessel Disease.

De Silva TM, Faraci FM.

Annu Rev Physiol. 2020 Feb 10;82:275-295. doi: 10.1146/annurev-physiol-021119-034338. Epub 2019 Oct 16.


Potential Unintended Effects of Standardized Pain Questionnaires: A Qualitative Study.

De Silva T, Hodges PW, Costa N, Setchell J.

Pain Med. 2020 Feb 1;21(2):e22-e33. doi: 10.1093/pm/pnz252.


High burden and seasonal variation of paediatric scabies and pyoderma prevalence in The Gambia: A cross-sectional study.

Armitage EP, Senghore E, Darboe S, Barry M, Camara J, Bah S, Marks M, Cerami C, Roca A, Antonio M, Turner CE, de Silva TI.

PLoS Negl Trop Dis. 2019 Oct 14;13(10):e0007801. doi: 10.1371/journal.pntd.0007801. eCollection 2019 Oct.


Crowned Dens Syndrome Illustrated by Dual Energy Computed Tomography Scan.

De Silva T, Rischin A.

J Clin Rheumatol. 2019 Sep 12. doi: 10.1097/RHU.0000000000001143. [Epub ahead of print] No abstract available.


Community-acquired Invasive Bacterial Disease in Urban Gambia, 2005-2015: A Hospital-based Surveillance.

Darboe S, Okomo U, Muhammad AK, Ceesay B, Jallow M, Usuf E, Tweed S, Akpalu E, Kwambana-Adams B, Kariuki S, Antonio M, Bradbury RS, Forrest K, de Silva TI, Lawal BJ, Nwakanma D, Secka O, Roca A.

Clin Infect Dis. 2019 Sep 5;69(Supplement_2):S105-S113. doi: 10.1093/cid/ciz463.


Coxsackievirus Type B3 Is a Potent Oncolytic Virus against KRAS-Mutant Lung Adenocarcinoma.

Deng H, Liu H, de Silva T, Xue Y, Mohamud Y, Ng CS, Qu J, Zhang J, Jia WWG, Lockwood WW, Luo H.

Mol Ther Oncolytics. 2019 Jul 23;14:266-278. doi: 10.1016/j.omto.2019.07.003. eCollection 2019 Sep 27.


Complexities in predicting the immunogenicity of live attenuated influenza vaccines.

Lindsey BB, Höschler K, de Silva TI.

Clin Infect Dis. 2019 Aug 14. pii: ciz773. doi: 10.1093/cid/ciz773. [Epub ahead of print] No abstract available.


Long noncoding RNAs are involved in multiple immunological pathways in response to vaccination.

de Lima DS, Cardozo LE, Maracaja-Coutinho V, Suhrbier A, Mane K, Jeffries D, Silveira ELV, Amaral PP, Rappuoli R, de Silva TI, Nakaya HI.

Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):17121-17126. doi: 10.1073/pnas.1822046116. Epub 2019 Aug 9.


Normality data of eGFR and validity of commonly used screening tests for CKD in an area with endemic CKD of unknown etiology; need for age and sex based precise cutoff values.

Herath N, Dassanayake R, Dissanayake M, Janitha C, Weerakoon K, Kumarasinghe C, de Silva TG, Agampodi S.

BMC Nephrol. 2019 Aug 5;20(1):298. doi: 10.1186/s12882-019-1477-9.


Tau and aging - Dialling up inflammation in the brain.

Kim HA, De Silva TM.

Brain Behav Immun. 2019 Oct;81:16-17. doi: 10.1016/j.bbi.2019.07.008. Epub 2019 Jul 6. No abstract available.


Automatic pedicle screw planning using atlas-based registration of anatomy and reference trajectories.

Vijayan R, De Silva T, Han R, Zhang X, Uneri A, Doerr S, Ketcha M, Perdomo-Pantoja A, Theodore N, Siewerdsen JH.

Phys Med Biol. 2019 Aug 21;64(16):165020. doi: 10.1088/1361-6560/ab2d66.


Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The Gambia: an open-label, observational, phase 4 study.

Lindsey BB, Jagne YJ, Armitage EP, Singanayagam A, Sallah HJ, Drammeh S, Senghore E, Mohammed NI, Jeffries D, Höschler K, Tregoning JS, Meijer A, Clarke E, Dong T, Barclay W, Kampmann B, de Silva TI.

Lancet Respir Med. 2019 Aug;7(8):665-676. doi: 10.1016/S2213-2600(19)30086-4. Epub 2019 Jun 21.


Prevalence of Panton-Valentine Leukocidin (PVL) and Antimicrobial Resistance in Community-Acquired Clinical Staphylococcus aureus in an Urban Gambian Hospital: A 11-Year Period Retrospective Pilot Study.

Darboe S, Dobreniecki S, Jarju S, Jallow M, Mohammed NI, Wathuo M, Ceesay B, Tweed S, Basu Roy R, Okomo U, Kwambana-Adams B, Antonio M, Bradbury RS, de Silva TI, Forrest K, Roca A, Lawal BJ, Nwakanma D, Secka O.

Front Cell Infect Microbiol. 2019 May 22;9:170. doi: 10.3389/fcimb.2019.00170. eCollection 2019.


Genomic and Epidemiological Evidence of a Dominant Panton-Valentine Leucocidin-Positive Methicillin Resistant Staphylococcus aureus Lineage in Sri Lanka and Presence Among Isolates From the United Kingdom and Australia.

McTavish SM, Snow SJ, Cook EC, Pichon B, Coleman S, Coombs GW, Pang S, Arias CA, Díaz L, Boldock E, Davies S, Udukala M, Kearns AM, Siribaddana S, de Silva TI.

Front Cell Infect Microbiol. 2019 Apr 26;9:123. doi: 10.3389/fcimb.2019.00123. eCollection 2019.


A Statistical Model for Rigid Image Registration Performance: The Influence of Soft-Tissue Deformation as a Confounding Noise Source.

Ketcha MD, De Silva T, Han R, Uneri A, Vogt S, Kleinszig G, Siewerdsen JH.

IEEE Trans Med Imaging. 2019 Sep;38(9):2016-2027. doi: 10.1109/TMI.2019.2907868. Epub 2019 Mar 27.


Atlas-based automatic planning and 3D-2D fluoroscopic guidance in pelvic trauma surgery.

Han R, Uneri A, De Silva T, Ketcha M, Goerres J, Vogt S, Kleinszig G, Osgood G, Siewerdsen JH.

Phys Med Biol. 2019 May 2;64(9):095022. doi: 10.1088/1361-6560/ab1456.


Reversible eruption of neurofibromatosis associated with tofacitinib therapy for rheumatoid arthritis.

Rischin A, De Silva T, Le Marshall K.

Rheumatology (Oxford). 2019 Jun 1;58(6):1111-1113. doi: 10.1093/rheumatology/kez012. No abstract available.


Influence of Anion Variations on Morphological, Spectral, and Physical Properties of the Propidium Luminophore.

De Silva TPD, Sahasrabudhe G, Yang B, Wang CH, Chhotaray PK, Nesterov EE, Warner IM.

J Phys Chem A. 2019 Jan 10;123(1):111-119. doi: 10.1021/acs.jpca.8b06948. Epub 2018 Dec 28.


A comparison of viral microneutralization and haemagglutination inhibition assays as measures of seasonal inactivated influenza vaccine immunogenicity in the first year after reduced intensity conditioning, lymphocyte depleted allogeneic haematopoietic stem cell transplant.

Miller PDE, de Silva TI, Leonard H, Anthias C, Hoschler K, Goddard K, Peggs K, Madrigal A, Snowden JA.

Vaccine. 2019 Jan 14;37(3):452-457. doi: 10.1016/j.vaccine.2018.11.061. Epub 2018 Dec 13.


The efficacy, effectiveness, and immunogenicity of influenza vaccines in Africa: a systematic review.

Lindsey BB, Armitage EP, Kampmann B, de Silva TI.

Lancet Infect Dis. 2019 Apr;19(4):e110-e119. doi: 10.1016/S1473-3099(18)30490-0. Epub 2018 Dec 12. Review. Erratum in: Lancet Infect Dis. 2019 Jun;19(6):e187.


Real-time, image-based slice-to-volume registration for ultrasound-guided spinal intervention.

De Silva T, Uneri A, Zhang X, Ketcha M, Han R, Sheth N, Martin A, Vogt S, Kleinszig G, Belzberg A, Sciubba DM, Siewerdsen JH.

Phys Med Biol. 2018 Oct 29;63(21):215016. doi: 10.1088/1361-6560/aae761.


A momentum-based diffeomorphic demons framework for deformable MR-CT image registration.

Han R, De Silva T, Ketcha M, Uneri A, Siewerdsen JH.

Phys Med Biol. 2018 Oct 24;63(21):215006. doi: 10.1088/1361-6560/aae66c.


Low-Bias RNA Sequencing of the HIV-2 Genome from Blood Plasma.

James KL, de Silva TI, Brown K, Whittle H, Taylor S, McVean G, Esbjörnsson J, Rowland-Jones SL.

J Virol. 2018 Dec 10;93(1). pii: e00677-18. doi: 10.1128/JVI.00677-18. Print 2019 Jan 1.


Sociodemographic and psychological determinants of influenza vaccine intention among recipients of autologous and allogeneic haematopoietic stem cell transplant: a cross-sectional survey of UK transplant recipients using a modified health belief model.

Miller PDE, Forster AS, de Silva TI, Leonard H, Anthias C, Mayhew M, Klammer M, Paskar S, Hurst E, Peggs K, Madrigal A, Snowden JA.

BMJ Open. 2018 Aug 8;8(8):e021222. doi: 10.1136/bmjopen-2017-021222.


Clinical Translation of the LevelCheck Decision Support Algorithm for Target Localization in Spine Surgery.

Manbachi A, De Silva T, Uneri A, Jacobson M, Goerres J, Ketcha M, Han R, Aygun N, Thompson D, Ye X, Vogt S, Kleinszig G, Molina C, Iyer R, Garzon-Muvdi T, Raber MR, Groves M, Wolinsky JP, Siewerdsen JH.

Ann Biomed Eng. 2018 Oct;46(10):1548-1557. doi: 10.1007/s10439-018-2099-2. Epub 2018 Jul 26.


Streamlining Decision Making in Contralateral Risk-Reducing Mastectomy: Impact of PREDICT and BOADICEA Computations.

de Silva TS, Russell VR, Henry FP, Thiruchelvam PTR, Hadjiminas DJ, Al-Mufti R, Hogben RK, Hunter J, Wood S, Jallali N, Leff DR.

Ann Surg Oncol. 2018 Oct;25(10):3057-3063. doi: 10.1245/s10434-018-6593-4. Epub 2018 Jul 17.


Potential impact of influenza vaccine roll-out on antibiotic use in Africa.

Knight GM, Clarkson M, de Silva TI.

J Antimicrob Chemother. 2018 Aug 1;73(8):2197-2200. doi: 10.1093/jac/dky172.


Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging.

De Silva TM, Li Y, Kinzenbaw DA, Sigmund CD, Faraci FM.

Hypertension. 2018 Jul;72(1):227-234. doi: 10.1161/HYPERTENSIONAHA.117.10799. Epub 2018 May 7.


Protocol for a cluster-randomised controlled trial evaluating the impact of a preschool-based capacity building intervention on intimate partner violence and substance misuse in Sri Lanka.

Lokuge K, Wallace P, Subasinghe K, Thurber K, De Silva T, Clarke N, Waas D, Liyanage N, Attygalle U, Carron-Arthur B, Rodrigo K, Banks E, D'Este C, Rajapakse T.

BMC Public Health. 2018 May 2;18(1):572. doi: 10.1186/s12889-018-5423-8.


Changes in Cerebral Arteries and Parenchymal Arterioles With Aging: Role of Rho Kinase 2 and Impact of Genetic Background.

De Silva TM, Modrick ML, Dabertrand F, Faraci FM.

Hypertension. 2018 May;71(5):921-927. doi: 10.1161/HYPERTENSIONAHA.118.10865. Epub 2018 Mar 12.


Virtual fluoroscopy for intraoperative C-arm positioning and radiation dose reduction.

De Silva T, Punnoose J, Uneri A, Mahesh M, Goerres J, Jacobson M, Ketcha MD, Manbachi A, Vogt S, Kleinszig G, Khanna AJ, Wolinksy JP, Siewerdsen JH, Osgood G.

J Med Imaging (Bellingham). 2018 Jan;5(1):015005. doi: 10.1117/1.JMI.5.1.015005. Epub 2018 Feb 13.


Acceptability of intranasal live attenuated influenza vaccine, influenza knowledge and vaccine intent in The Gambia.

Armitage EP, Camara J, Bah S, Forster AS, Clarke E, Kampmann B, de Silva TI.

Vaccine. 2018 Mar 20;36(13):1772-1780. doi: 10.1016/j.vaccine.2018.02.037. Epub 2018 Feb 23.


Vitamin D3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke.

Evans MA, Kim HA, Ling YH, Uong S, Vinh A, De Silva TM, Arumugam TV, Clarkson AN, Zosky GR, Drummond GR, Broughton BRS, Sobey CG.

Neuromolecular Med. 2018 Mar;20(1):147-159. doi: 10.1007/s12017-018-8484-z. Epub 2018 Feb 23.


Population Control Policies and Fertility Convergence.

de Silva T, Tenreyro S.

J Econ Perspect. 2017;31(4):205-28. No abstract available.


Getting the Ploceidae tree right.

De Silva TN, Bates JM, Peterson AT.

Mol Phylogenet Evol. 2019 Feb;131:228. doi: 10.1016/j.ympev.2018.02.004. Epub 2018 Feb 7. No abstract available.


Frailty Screening (FRAIL-NH) and Mortality in French Nursing Homes: Results From the Incidence of Pneumonia and Related Consequences in Nursing Home Residents Study.

De Silva TR, Theou O, Vellas B, Cesari M, Visvanathan R.

J Am Med Dir Assoc. 2018 May;19(5):411-414. doi: 10.1016/j.jamda.2017.12.101.


HLA-associated polymorphisms in the HIV-2 capsid highlight key differences between HIV-1 and HIV-2 immune adaptation.

de Silva TI, Leligdowicz A, Carlson J, Garcia-Knight M, Onyango C, Miller N, Yindom LM, Hué S, Jaye A, Dong T, Cotten M, Rowland-Jones SL.

AIDS. 2018 Mar 27;32(6):709-714. doi: 10.1097/QAD.0000000000001753.


Identification and validation of FaP1D7, a putative marker associated with the biosynthesis of methyl butanoate in cultivated strawberry (Fragaria x ananassa).

Gor MC, Candappa C, de Silva T, Mantri N, Pang E.

Sci Rep. 2017 Dec 12;7(1):17454. doi: 10.1038/s41598-017-17448-1.


Enhanced pre-operative axillary staging using intradermal microbubbles and contrast-enhanced ultrasound to detect and biopsy sentinel lymph nodes in breast cancer: a potential replacement for axillary surgery.

Cox K, Taylor-Phillips S, Sharma N, Weeks J, Mills P, Sever A, Lim A, Haigh I, Hashem M, de Silva T, Satchithananda K, Tang M, Wallis M.

Br J Radiol. 2018 Feb;91(1082):20170626. doi: 10.1259/bjr.20170626. Epub 2017 Dec 5.


A line fiducial method for geometric calibration of cone-beam CT systems with diverse scan trajectories.

Jacobson MW, Ketcha MD, Capostagno S, Martin A, Uneri A, Goerres J, De Silva T, Reaungamornrat S, Han R, Manbachi A, Stayman JW, Vogt S, Kleinszig G, Siewerdsen JH.

Phys Med Biol. 2018 Jan 16;63(2):025030. doi: 10.1088/1361-6560/aa9910.


Planning, guidance, and quality assurance of pelvic screw placement using deformable image registration.

Goerres J, Uneri A, Jacobson M, Ramsay B, De Silva T, Ketcha M, Han R, Manbachi A, Vogt S, Kleinszig G, Wolinsky JP, Osgood G, Siewerdsen JH.

Phys Med Biol. 2017 Nov 13;62(23):9018-9038. doi: 10.1088/1361-6560/aa954f.


Deformable 3D-2D Registration for Guiding K-Wire Placement in Pelvic Trauma Surgery.

Goerres J, Jacobson M, Uneri A, De Silva T, Ketcha M, Reaungamornrat S, Vogt S, Kleinszig G, Wolinsky JP, Osgood G, Siewerdsen JH.

Proc SPIE Int Soc Opt Eng. 2017 Mar;10135. pii: 101350A. doi: 10.1117/12.2255952.


Geometric Calibration Using Line Fiducials for Cone-Beam CT with General, Non-Circular Source-Detector Trajectories.

Jacobson MW, Ketcha M, Uneri A, Goerres J, De Silva T, Reaungamornrat S, Vogt S, Kleinszig G, Siewerdsen JH.

Proc SPIE Int Soc Opt Eng. 2017 Mar;10132. pii: 101320I. doi: 10.1117/12.2255724.


General practitioners' experiences and perceptions of mild moderate depression management and factors influencing effective service delivery in rural Australian communities: a qualitative study.

De Silva T, Prakash A, Yarlagadda S, Johns MD, Sandy K, Hansen V, Phelan S, Pit S.

Int J Ment Health Syst. 2017 Sep 18;11:54. doi: 10.1186/s13033-017-0159-x. eCollection 2017.

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