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The Social Health Insurance Scheme for Pubic Sector Employees in Sri Lanka and Its Effect on Reducing the Financial Burden of Illness.

Karunaratna S, Ranasinghe T, Chandraratne N, De Silva A.

Asia Pac J Public Health. 2019 Jul 17:1010539519862422. doi: 10.1177/1010539519862422. [Epub ahead of print]


Relevance of heat stress and dehydration to chronic kidney disease (CKDu) in Sri Lanka.

Jayasekara KB, Kulasooriya PN, Wijayasiri KN, Rajapakse ED, Dulshika DS, Bandara P, Fried LF, De Silva A, Albert SM.

Prev Med Rep. 2019 Jun 22;15:100928. doi: 10.1016/j.pmedr.2019.100928. eCollection 2019 Sep.


Effectiveness of a Bundled Intervention Including Adjunctive Corticosteroids on Outcomes of Hospitalized Patients With Community-Acquired Pneumonia: A Stepped-Wedge Randomized Clinical Trial.

Lloyd M, Karahalios A, Janus E, Skinner EH, Haines T, De Silva A, Lowe S, Shackell M, Ko S, Desmond L, Karunajeewa H; Improving Evidence-Based Treatment Gaps and Outcomes in Community-Acquired Pneumonia (IMPROVE-GAP) Implementation Team at Western Health.

JAMA Intern Med. 2019 Jul 8. doi: 10.1001/jamainternmed.2019.1438. [Epub ahead of print]


Severe acute pain and persistent post-surgical pain in orthopaedic trauma patients: a cohort study.

Edgley C, Hogg M, De Silva A, Braat S, Bucknill A, Leslie K.

Br J Anaesth. 2019 Jun 24. pii: S0007-0912(19)30434-9. doi: 10.1016/j.bja.2019.05.030. [Epub ahead of print]


Reducing childhood malnutrition in Bangladesh: the importance of addressing socio-economic inequalities.

Islam MR, Rahman MS, Rahman MM, Nomura S, de Silva A, Lanerolle P, Jung J, Rahman MM.

Public Health Nutr. 2019 Jun 17:1-11. doi: 10.1017/S136898001900140X. [Epub ahead of print]


Bioaccumulation and translocation of tetrabromobisphenol A and hexabromocyclododecanes in mangrove plants from a national nature reserve of Shenzhen City, South China.

Li H, Hu Y, Sun Y, De Silva AO, Muir DCG, Wang W, Xie J, Xu X, Pei N, Xiong Y, Luo X, Mai B.

Environ Int. 2019 Aug;129:239-246. doi: 10.1016/j.envint.2019.05.034. Epub 2019 May 27.


A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection.

Kose N, Fox JM, Sapparapu G, Bombardi R, Tennekoon RN, de Silva AD, Elbashir SM, Theisen MA, Humphris-Narayanan E, Ciaramella G, Himansu S, Diamond MS, Crowe JE Jr.

Sci Immunol. 2019 May 17;4(35). pii: eaaw6647. doi: 10.1126/sciimmunol.aaw6647.


Awareness of human papillomavirus, cervical cancer and its prevention among primigravid antenatal clinic attendees in a tertiary care hospital in Sri Lanka: a cross-sectional study.

de Silva AHW, Samarawickrema N, Kasturiratne A, Skinner SR, Wickremasinghe AR, Garland SM.

Sex Health. 2019 May 15. doi: 10.1071/SH18080. [Epub ahead of print]


Family-centred oral health promotion through Victorian child-health services: a pilot.

Heilbrunn-Lang AY, Carpenter LM, de Silva AM, Meyenn LK, Lang G, Ridge A, Perry A, Cole D, Hegde S.

Health Promot Int. 2019 Apr 21. pii: daz025. doi: 10.1093/heapro/daz025. [Epub ahead of print]


Human antibody response to Zika targets type-specific quaternary structure epitopes.

Collins MH, Tu HA, Gimblet-Ochieng C, Liou GA, Jadi RS, Metz SW, Thomas A, McElvany BD, Davidson E, Doranz BJ, Reyes Y, Bowman NM, Becker-Dreps S, Bucardo F, Lazear HM, Diehl SA, de Silva AM.

JCI Insight. 2019 Apr 18;4(8). pii: 124588. doi: 10.1172/jci.insight.124588. eCollection 2019 Apr 18.


Precise Proton Mapping near Ionic Micellar Membranes with Fluorescent Photoinduced-Electron-Transfer Sensors.

Uchiyama S, Yano K, Fukatsu E, de Silva AP.

Chemistry. 2019 Jun 26;25(36):8522-8527. doi: 10.1002/chem.201806270. Epub 2019 May 15.


Beyond Neutralizing Antibody Levels: The Epitope Specificity of Antibodies Induced by National Institutes of Health Monovalent Dengue Virus Vaccines.

Swanstrom JA, Nivarthi UK, Patel B, Delacruz MJ, Yount B, Widman DG, Durbin AP, Whitehead SS, De Silva AM, Baric RS.

J Infect Dis. 2019 Jun 19;220(2):219-227. doi: 10.1093/infdis/jiz109.


Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles.

Tian Y, Babor M, Lane J, Seumois G, Liang S, Goonawardhana NDS, De Silva AD, Phillips EJ, Mallal SA, da Silva Antunes R, Grifoni A, Vijayanand P, Weiskopf D, Peters B, Sette A.

J Clin Invest. 2019 Mar 18;130:1727-1741. doi: 10.1172/JCI123726. eCollection 2019 Mar 18.


Population analysis to increase the robustness of molecular computational identification and its extension into the near-infrared for substantial numbers of small objects.

Yao C, Ling J, Chen L, de Silva AP.

Chem Sci. 2019 Jan 16;10(8):2272-2279. doi: 10.1039/c8sc05548c. eCollection 2019 Feb 28.


Longitudinal analysis of acute and convalescent B cell responses in a human primary dengue serotype 2 infection model.

Nivarthi UK, Tu HA, Delacruz MJ, Swanstrom J, Patel B, Durbin AP, Whitehead SS, Pierce KK, Kirkpatrick BD, Baric RS, Nguyen N, Emerling DE, de Silva AM, Diehl SA.

EBioMedicine. 2019 Mar;41:465-478. doi: 10.1016/j.ebiom.2019.02.060. Epub 2019 Mar 8.


Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika.

Andrade P, Gimblet-Ochieng C, Modirian F, Collins M, Cárdenas M, Katzelnick LC, Montoya M, Michlmayr D, Kuan G, Balmaseda A, Coloma J, de Silva AM, Harris E.

Nat Commun. 2019 Feb 26;10(1):938. doi: 10.1038/s41467-019-08845-3.


Characterization of perfluoroalkyl substances in sediment cores from High and Low Arctic lakes in Canada.

MacInnis JJ, Lehnherr I, Muir DCG, Quinlan R, De Silva AO.

Sci Total Environ. 2019 May 20;666:414-422. doi: 10.1016/j.scitotenv.2019.02.210. Epub 2019 Feb 15.


Description of a new species of the genus Cnemaspis Strauch, 1887 (Reptilia: Squamata: Gekkonidae) from the Nilgala Savannah forest, Uva Province of Sri Lanka.

Karunarathna S, Bauer AM, De Silva A, Surasinghe T, Somaratna L, Madawala M, Gabadage D, Botejue M, Henkanaththegedara S, Ukuwela KDB.

Zootaxa. 2019 Jan 17;4545(3):389-407. doi: 10.11646/zootaxa.4545.3.4.


Addressing the information deficit in global health: lessons from a digital acute care platform in Sri Lanka.

Beane A, De Silva AP, Athapattu PL, Jayasinghe S, Abayadeera AU, Wijerathne M, Udayanga I, Rathnayake S, Dondorp AM, Haniffa R.

BMJ Glob Health. 2019 Jan 29;4(1):e001134. doi: 10.1136/bmjgh-2018-001134. eCollection 2019.


Deposition and Source Identification of Nitrogen Heterocyclic Polycyclic Aromatic Compounds in Snow, Sediment, and Air Samples from the Athabasca Oil Sands Region.

Chibwe L, Manzano CA, Muir D, Atkinson B, Kirk JL, Marvin CH, Wang X, Teixeira C, Shang D, Harner T, De Silva AO.

Environ Sci Technol. 2019 Mar 19;53(6):2981-2989. doi: 10.1021/acs.est.8b06175. Epub 2019 Mar 6.


Occurrence of substituted diphenylamine antioxidants and benzotriazole UV stabilizers in Arctic seabirds and seals.

Lu Z, De Silva AO, Provencher JF, Mallory ML, Kirk JL, Houde M, Stewart C, Braune BM, Avery-Gomm S, Muir DCG.

Sci Total Environ. 2019 May 1;663:950-957. doi: 10.1016/j.scitotenv.2019.01.354. Epub 2019 Jan 28.


Molecular memory with downstream logic processing exemplified by switchable and self-indicating guest capture and release.

Daly B, Moody TS, Huxley AJM, Yao C, Schazmann B, Alves-Areias A, Malone JF, Gunaratne HQN, Nockemann P, de Silva AP.

Nat Commun. 2019 Jan 21;10(1):49. doi: 10.1038/s41467-018-07902-7.


Multiple imputation methods for handling missing values in a longitudinal categorical variable with restrictions on transitions over time: a simulation study.

De Silva AP, Moreno-Betancur M, De Livera AM, Lee KJ, Simpson JA.

BMC Med Res Methodol. 2019 Jan 10;19(1):14. doi: 10.1186/s12874-018-0653-0.


Respiratory Viral Infection: An Underappreciated Cause of Acute Febrile Illness Admissions in Southern Sri Lanka.

Tillekeratne LG, Bodinayake CK, Simmons R, Nagahawatte A, Devasiri V, Kodikara Arachchi W, Nicholson BP, Park LP, Vanderburg S, Kurukulasooriya R, De Silva AD, Østybe T, Reller ME, Woods CW.

Am J Trop Med Hyg. 2019 Mar;100(3):672-680. doi: 10.4269/ajtmh.18-0699.


Distribution and fate of synthetic phenolic antioxidants in various wastewater treatment processes in Canada.

Lu Z, Smyth SA, De Silva AO.

Chemosphere. 2019 Mar;219:826-835. doi: 10.1016/j.chemosphere.2018.12.068. Epub 2018 Dec 11.


Lean non-alcoholic fatty liver disease (lean NAFLD): characteristics, metabolic outcomes and risk factors from a 7-year prospective, community cohort study from Sri Lanka.

Niriella MA, Kasturiratne A, Pathmeswaran A, De Silva ST, Perera KR, Subasinghe SKCE, Kodisinghe SK, Piyaratna TACL, Vithiya K, Dassanayaka AS, De Silva AP, Wickramasinghe AR, Takeuchi F, Kato N, de Silva HJ.

Hepatol Int. 2019 May;13(3):314-322. doi: 10.1007/s12072-018-9916-4. Epub 2018 Dec 11.


Legacy and Emerging Persistent Organic Pollutants (POPs) in Terrestrial Compartments in the High Arctic: Sorption and Secondary Sources.

Cabrerizo A, Muir DCG, De Silva AO, Wang X, Lamoureux SF, Lafrenière MJ.

Environ Sci Technol. 2018 Dec 18;52(24):14187-14197. doi: 10.1021/acs.est.8b05011. Epub 2018 Dec 6.


Dengue type 1 viruses circulating in humans are highly infectious and poorly neutralized by human antibodies.

Raut R, Corbett KS, Tennekoon RN, Premawansa S, Wijewickrama A, Premawansa G, Mieczkowski P, Rückert C, Ebel GD, De Silva AD, de Silva AM.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):227-232. doi: 10.1073/pnas.1812055115. Epub 2018 Dec 5.


Deconstruction of an African folk medicine uncovers a novel molecular strategy for therapeutic potassium channel activation.

De Silva AM, Manville RW, Abbott GW.

Sci Adv. 2018 Nov 14;4(11):eaav0824. doi: 10.1126/sciadv.aav0824. eCollection 2018 Nov.


Cutting Edge: Transcriptional Profiling Reveals Multifunctional and Cytotoxic Antiviral Responses of Zika Virus-Specific CD8+ T Cells.

Grifoni A, Costa-Ramos P, Pham J, Tian Y, Rosales SL, Seumois G, Sidney J, de Silva AD, Premkumar L, Collins MH, Stone M, Norris PJ, Romero CME, Durbin A, Ricciardi MJ, Ledgerwood JE, de Silva AM, Busch M, Peters B, Vijayanand P, Harris E, Falconar AK, Kallas E, Weiskopf D, Sette A.

J Immunol. 2018 Dec 15;201(12):3487-3491. doi: 10.4049/jimmunol.1801090. Epub 2018 Nov 9.


Evolution of nuchal glands, unusual defensive organs of Asian natricine snakes (Serpentes: Colubridae), inferred from a molecular phylogeny.

Takeuchi H, Savitzky AH, Ding L, de Silva A, Das I, Nguyen TT, Tsai TS, Jono T, Zhu GX, Mahaulpatha D, Tang Y, Mori A.

Ecol Evol. 2018 Sep 21;8(20):10219-10232. doi: 10.1002/ece3.4497. eCollection 2018 Oct.


Genetic Variation between Dengue Virus Type 4 Strains Impacts Human Antibody Binding and Neutralization.

Gallichotte EN, Baric TJ, Nivarthi U, Delacruz MJ, Graham R, Widman DG, Yount BL, Durbin AP, Whitehead SS, de Silva AM, Baric RS.

Cell Rep. 2018 Oct 30;25(5):1214-1224. doi: 10.1016/j.celrep.2018.10.006.


Fifteen Nanometer Resolved Patterns in Selective Area Atomic Layer Deposition-Defectivity Reduction by Monolayer Design.

Wojtecki R, Mettry M, Fine Nathel NF, Friz A, De Silva A, Arellano N, Shobha H.

ACS Appl Mater Interfaces. 2018 Nov 7;10(44):38630-38637. doi: 10.1021/acsami.8b13896. Epub 2018 Oct 29.


Melioidosis in Sri Lanka.

Corea EM, de Silva AD, Thevanesam V.

Trop Med Infect Dis. 2018 Feb 21;3(1). pii: E22. doi: 10.3390/tropicalmed3010022.


Study protocol: a pilot randomized controlled trial to evaluate the acceptability and feasibility of a counseling intervention, delivered by nurses, for those who have attempted self-poisoning in Sri Lanka.

De Silva ANLM, Dawson AH, Gawarammana IB, Tennakoon S, Rajapakse T.

Pilot Feasibility Stud. 2018 Sep 24;4:150. doi: 10.1186/s40814-018-0341-1. eCollection 2018.


Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype.

Metz SW, Thomas A, Brackbill A, Xianwen Y, Stone M, Horvath K, Miley MJ, Luft C, DeSimone JM, Tian S, de Silva AM.

PLoS Negl Trop Dis. 2018 Sep 24;12(9):e0006793. doi: 10.1371/journal.pntd.0006793. eCollection 2018 Sep.


Preliminary study on chronic granulomatous disease in Sri Lanka.

Fernando SJA, Faiz NM, Handunnetti SM, De Silva AD, Dasanayake WMDK, Wickramasinghe GD, Karunatilake RMCH, de Silva NR.

Allergy Asthma Clin Immunol. 2018 Sep 17;14:37. doi: 10.1186/s13223-018-0264-7. eCollection 2018.


Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial.

Webster R, Salam A, de Silva HA, Selak V, Stepien S, Rajapakse S, Amarasekara S, Amarasena N, Billot L, de Silva AP, Fernando M, Guggilla R, Jan S, Jayawardena J, Maulik PK, Mendis S, Mendis S, Munasinghe J, Naik N, Prabhakaran D, Ranasinghe G, Thom S, Tisserra N, Senaratne V, Wijekoon S, Wijeyasingam S, Rodgers A, Patel A; TRIUMPH Study Group.

JAMA. 2018 Aug 14;320(6):566-579. doi: 10.1001/jama.2018.10359. Erratum in: JAMA. 2018 Nov 13;320(18):1940.


Substituted diphenylamine antioxidants and benzotriazole UV stabilizers in blood plasma of fish, turtles, birds and dolphins from North America.

Lu Z, De Silva AO, Zhou W, Tetreault GR, de Solla SR, Fair PA, Houde M, Bossart G, Muir DCG.

Sci Total Environ. 2019 Jan 10;647:182-190. doi: 10.1016/j.scitotenv.2018.07.405. Epub 2018 Jul 30.


Is Total Serum Nitrite and Nitrate (NOx) Level in Dengue Patients a Potential Prognostic Marker of Dengue Hemorrhagic Fever?

Mapalagamage M, Handunnetti S, Premawansa G, Thillainathan S, Fernando T, Kanapathippillai K, Wickremasinghe R, De Silva AD, Premawansa S.

Dis Markers. 2018 Jul 5;2018:5328681. doi: 10.1155/2018/5328681. eCollection 2018.


Seroepidemiology of Dengue, Zika, and Yellow Fever Viruses among Children in the Democratic Republic of the Congo.

Willcox AC, Collins MH, Jadi R, Keeler C, Parr JB, Mumba D, Kashamuka M, Tshefu A, de Silva AM, Meshnick SR.

Am J Trop Med Hyg. 2018 Sep;99(3):756-763. doi: 10.4269/ajtmh.18-0156. Epub 2018 Jul 5.


Economic costs of alcohol use in Sri Lanka.

Ranaweera S, Amarasinghe H, Chandraratne N, Thavorncharoensap M, Ranasinghe T, Karunaratna S, Kumara D, Santatiwongchai B, Chaikledkaew U, Abeykoon P, De Silva A.

PLoS One. 2018 Jun 7;13(6):e0198640. doi: 10.1371/journal.pone.0198640. eCollection 2018.


Viral Entry and NS1 as Potential Antiviral Drug Targets.

de Silva AM, Rey FA, Young PR, Hilgenfeld R, Vasudevan SG.

Adv Exp Med Biol. 2018;1062:107-113. doi: 10.1007/978-981-10-8727-1_8. Review.


The Molecular Specificity of the Human Antibody Response to Dengue Virus Infections.

Gallichotte EN, Baric RS, de Silva AM.

Adv Exp Med Biol. 2018;1062:63-76. doi: 10.1007/978-981-10-8727-1_5. Review.


Analyzing the Human Serum Antibody Responses to a Live Attenuated Tetravalent Dengue Vaccine Candidate.

Swanstrom JA, Henein S, Plante JA, Yount BL, Widman DG, Gallichotte EN, Dean HJ, Osorio JE, Partidos CD, de Silva AM, Baric RS.

J Infect Dis. 2018 May 25;217(12):1932-1941. doi: 10.1093/infdis/jiy063.


Association of the Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) Score With Excess Hospital Mortality in Adults With Suspected Infection in Low- and Middle-Income Countries.

Rudd KE, Seymour CW, Aluisio AR, Augustin ME, Bagenda DS, Beane A, Byiringiro JC, Chang CH, Colas LN, Day NPJ, De Silva AP, Dondorp AM, Dünser MW, Faiz MA, Grant DS, Haniffa R, Van Hao N, Kennedy JN, Levine AC, Limmathurotsakul D, Mohanty S, Nosten F, Papali A, Patterson AJ, Schieffelin JS, Shaffer JG, Thuy DB, Thwaites CL, Urayeneza O, White NJ, West TE, Angus DC; Sepsis Assessment and Identification in Low Resource Settings (SAILORS) Collaboration.

JAMA. 2018 Jun 5;319(21):2202-2211. doi: 10.1001/jama.2018.6229.


Dissolved Organophosphate Esters and Polybrominated Diphenyl Ethers in Remote Marine Environments: Arctic Surface Water Distributions and Net Transport through Fram Strait.

McDonough CA, De Silva AO, Sun C, Cabrerizo A, Adelman D, Soltwedel T, Bauerfeind E, Muir DCG, Lohmann R.

Environ Sci Technol. 2018 Jun 5;52(11):6208-6216. doi: 10.1021/acs.est.8b01127. Epub 2018 May 22.


Metabolic acidosis in short bowel syndrome: think D-lactic acid acidosis.

Stanciu S, De Silva A.

BMJ Case Rep. 2018 May 16;2018. pii: bcr-2018-224221. doi: 10.1136/bcr-2018-224221.


The distal radius palmar cortical angle in adolescent versus adult populations.

Breheny S, Chang AC, De Silva A, Allcock P.

J Orthop Surg (Hong Kong). 2018 May-Aug;26(2):2309499018772378. doi: 10.1177/2309499018772378.


Association Between DMSO and Sugars in the Sperm Cryopreservation of Pacu.

Pires DM, Corcini CD, de Silva AC, Gheller SM, Pereira FA, Pereira JR, Muelbert JR, Jardim RD, Garcia JR, Varela AS Jr.

Cryo Letters. 2018 Mar/Apr;39(2):121-130.


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