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Items: 7


FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

Essers MA, Weijzen S, de Vries-Smits AM, Saarloos I, de Ruiter ND, Bos JL, Burgering BM.

EMBO J. 2004 Dec 8;23(24):4802-12. Epub 2004 Nov 11.


Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38.

Ouwens DM, de Ruiter ND, van der Zon GC, Carter AP, Schouten J, van der Burgt C, Kooistra K, Bos JL, Maassen JA, van Dam H.

EMBO J. 2002 Jul 15;21(14):3782-93.


Ras-dependent regulation of c-Jun phosphorylation is mediated by the Ral guanine nucleotide exchange factor-Ral pathway.

de Ruiter ND, Wolthuis RM, van Dam H, Burgering BM, Bos JL.

Mol Cell Biol. 2000 Nov;20(22):8480-8.


Direct control of the Forkhead transcription factor AFX by protein kinase B.

Kops GJ, de Ruiter ND, De Vries-Smits AM, Powell DR, Bos JL, Burgering BM.

Nature. 1999 Apr 15;398(6728):630-4.


The Rap1 GTPase functions as a regulator of morphogenesis in vivo.

Asha H, de Ruiter ND, Wang MG, Hariharan IK.

EMBO J. 1999 Feb 1;18(3):605-15.


Stimulation of gene induction and cell growth by the Ras effector Rlf.

Wolthuis RM, de Ruiter ND, Cool RH, Bos JL.

EMBO J. 1997 Nov 17;16(22):6748-61.

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