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Items: 1 to 50 of 307

1.

A Single Biosynthetic Gene Cluster Is Responsible for the Production of Bagremycin Antibiotics and Ferroverdin Iron Chelators.

Martinet L, Naômé A, Deflandre B, Maciejewska M, Tellatin D, Tenconi E, Smargiasso N, de Pauw E, van Wezel GP, Rigali S.

MBio. 2019 Aug 13;10(4). pii: e01230-19. doi: 10.1128/mBio.01230-19.

2.

Exploring the N-Glycosylation Profile of Glycoprotein B from Human Cytomegalovirus Expressed in CHO and Nicotiana tabacum BY-2 Cells.

Smargiasso N, Nader J, Rioux S, Mazzucchelli G, Boutry M, De Pauw E, Chaumont F, Navarre C.

Int J Mol Sci. 2019 Jul 31;20(15). pii: E3741. doi: 10.3390/ijms20153741.

3.

Proteomics highlights common and distinct pathophysiological processes associated to ileal and colonic ulcers in Crohn's disease.

Pierre N, Salée C, Massot C, Blétard N, Mazzucchelli G, Smargiasso N, Morsa D, Baiwir D, De Pauw E, Reenaers C, Van Kemseke C, Loly JP, Delvenne P, Meuwis MA, Louis E.

J Crohns Colitis. 2019 Jul 8. pii: jjz130. doi: 10.1093/ecco-jcc/jjz130. [Epub ahead of print]

PMID:
31282946
4.

Precise co-registration of mass spectrometry imaging, histology, and laser microdissection-based omics.

Dewez F, Martin-Lorenzo M, Herfs M, Baiwir D, Mazzucchelli G, De Pauw E, Heeren RMA, Balluff B.

Anal Bioanal Chem. 2019 Sep;411(22):5647-5653. doi: 10.1007/s00216-019-01983-z. Epub 2019 Jul 1.

5.

Bacillus licheniformis peptidoglycan characterization by CZE-MS: Assessment with the benchmark RP-HPLC-MS method.

Boulanger M, Delvaux C, Quinton L, Joris B, De Pauw E, Far J.

Electrophoresis. 2019 Jun 6. doi: 10.1002/elps.201900147. [Epub ahead of print]

PMID:
31169927
6.

Fundamental Studies on Poly(2-oxazoline) Side Chain Isomers Using Tandem Mass Spectrometry and Ion Mobility-Mass Spectrometry.

Haler JRN, de la Rosa VR, Massonnet P, Far J, Hoogenboom R, De Pauw E.

J Am Soc Mass Spectrom. 2019 Jul;30(7):1220-1228. doi: 10.1007/s13361-019-02173-y. Epub 2019 Apr 4.

PMID:
30949970
7.

The N-glycan profile of the peritrophic membrane in the Colorado potato beetle larva (Leptinotarsa decemlineata).

Liu D, De Schutter K, Smargiasso N, De Pauw E, Van Damme EJM, Smagghe G.

J Insect Physiol. 2019 May - Jun;115:27-32. doi: 10.1016/j.jinsphys.2019.03.009. Epub 2019 Mar 29.

PMID:
30935980
8.

Identification of new bioactive peptides from Kefir milk through proteopeptidomics: Bioprospection of antihypertensive molecules.

Amorim FG, Coitinho LB, Dias AT, Friques AGF, Monteiro BL, Rezende LCD, Pereira TMC, Campagnaro BP, De Pauw E, Vasquez EC, Quinton L.

Food Chem. 2019 Jun 1;282:109-119. doi: 10.1016/j.foodchem.2019.01.010. Epub 2019 Jan 8.

PMID:
30711094
9.

Recommendations for reporting ion mobility Mass Spectrometry measurements.

Gabelica V, Shvartsburg AA, Afonso C, Barran P, Benesch JLP, Bleiholder C, Bowers MT, Bilbao A, Bush MF, Campbell JL, Campuzano IDG, Causon T, Clowers BH, Creaser CS, De Pauw E, Far J, Fernandez-Lima F, Fjeldsted JC, Giles K, Groessl M, Hogan CJ Jr, Hann S, Kim HI, Kurulugama RT, May JC, McLean JA, Pagel K, Richardson K, Ridgeway ME, Rosu F, Sobott F, Thalassinos K, Valentine SJ, Wyttenbach T.

Mass Spectrom Rev. 2019 May;38(3):291-320. doi: 10.1002/mas.21585. Epub 2019 Feb 1. Review.

10.

The N-glycome of the hemipteran pest insect Nilaparvata lugens reveals unexpected sex differences.

Scheys F, De Schutter K, Shen Y, Yu N, Smargiasso N, De Pauw E, Van Damme EJM, Smagghe G.

Insect Biochem Mol Biol. 2019 Apr;107:39-45. doi: 10.1016/j.ibmb.2019.01.008. Epub 2019 Jan 28.

PMID:
30703540
11.

Towards the use of ion mobility mass spectrometry derived collision cross section as a screening approach for unambiguous identification of targeted pesticides in food.

Goscinny S, McCullagh M, Far J, De Pauw E, Eppe G.

Rapid Commun Mass Spectrom. 2019 Jan 24. doi: 10.1002/rcm.8395. [Epub ahead of print]

PMID:
30677180
12.

Gas-Phase Dynamics of Collision Induced Unfolding, Collision Induced Dissociation, and Electron Transfer Dissociation-Activated Polymer Ions.

Haler JRN, Massonnet P, Far J, de la Rosa VR, Lecomte P, Hoogenboom R, Jérôme C, De Pauw E.

J Am Soc Mass Spectrom. 2019 Apr;30(4):563-572. doi: 10.1007/s13361-018-2115-7. Epub 2018 Dec 6.

PMID:
30523570
13.

New Insights on Moojase, a Thrombin-Like Serine Protease from Bothrops moojeni Snake Venom.

Amorim FG, Menaldo DL, Carone SEI, Silva TA, Sartim MA, De Pauw E, Quinton L, Sampaio SV.

Toxins (Basel). 2018 Nov 28;10(12). pii: E500. doi: 10.3390/toxins10120500.

14.

In-Depth Venome of the Brazilian Rattlesnake Crotalus durissus terrificus: An Integrative Approach Combining Its Venom Gland Transcriptome and Venom Proteome.

Wiezel GA, Shibao PYT, Cologna CT, Morandi Filho R, Ueira-Vieira C, De Pauw E, Quinton L, Arantes EC.

J Proteome Res. 2018 Nov 2;17(11):3941-3958. doi: 10.1021/acs.jproteome.8b00610. Epub 2018 Oct 16.

PMID:
30270628
15.

Microproteomic Profiling of High-Grade Squamous Intraepithelial Lesion of the Cervix: Insight into Biological Mechanisms of Dysplasia and New Potential Diagnostic Markers.

Pottier C, Kriegsmann M, Alberts D, Smargiasso N, Baiwir D, Mazzucchelli G, Herfs M, Fresnais M, Casadonte R, Delvenne P, De Pauw E, Longuespée R.

Proteomics Clin Appl. 2019 Jan;13(1):e1800052. doi: 10.1002/prca.201800052. Epub 2018 Aug 23.

PMID:
30094940
16.

Effectiveness and Limitations of Computational Chemistry and Mass Spectrometry in the Rational Design of Target-specific Shift Reagents for Ion Mobility Spectrometry.

Kune C, Haler JRN, Far J, De Pauw E.

Chemphyschem. 2018 Nov 5;19(21):2921-2930. doi: 10.1002/cphc.201800555. Epub 2018 Aug 21.

PMID:
30071143
17.

Disulfide Connectivity Analysis of Peptides Bearing Two Intramolecular Disulfide Bonds Using MALDI In-Source Decay.

Massonnet P, Haler JRN, Upert G, Smargiasso N, Mourier G, Gilles N, Quinton L, De Pauw E.

J Am Soc Mass Spectrom. 2018 Oct;29(10):1995-2002. doi: 10.1007/s13361-018-2022-y. Epub 2018 Jul 9.

PMID:
29987664
18.

Proteopeptidomic, Functional and Immunoreactivity Characterization of Bothrops moojeni Snake Venom: Influence of Snake Gender on Venom Composition.

Amorim FG, Costa TR, Baiwir D, De Pauw E, Quinton L, Sampaio SV.

Toxins (Basel). 2018 Apr 26;10(5). pii: E177. doi: 10.3390/toxins10050177.

19.

Predicting Ion Mobility-Mass Spectrometry trends of polymers using the concept of apparent densities.

Haler JRN, Morsa D, Lecomte P, Jérôme C, Far J, De Pauw E.

Methods. 2018 Jul 15;144:125-133. doi: 10.1016/j.ymeth.2018.03.010. Epub 2018 Mar 28.

PMID:
29601857
20.

Peptidomic investigation of Neoponera villosa venom by high-resolution mass spectrometry: seasonal and nesting habitat variations.

Cologna CT, Rodrigues RS, Santos J, de Pauw E, Arantes EC, Quinton L.

J Venom Anim Toxins Incl Trop Dis. 2018 Feb 17;24:6. doi: 10.1186/s40409-018-0141-3. eCollection 2018.

21.

Heterologous expression of rTsHyal-1: the first recombinant hyaluronidase of scorpion venom produced in Pichia pastoris system.

Amorim FG, Boldrini-França J, de Castro Figueiredo Bordon K, Cardoso IA, De Pauw E, Quinton L, Kashima S, Arantes EC.

Appl Microbiol Biotechnol. 2018 Apr;102(7):3145-3158. doi: 10.1007/s00253-018-8821-z. Epub 2018 Feb 17.

PMID:
29455388
22.

Laser Microdissection-Based Microproteomics of Formalin-Fixed and Paraffin-Embedded (FFPE) Tissues.

Longuespée R, Baiwir D, Mazzucchelli G, Smargiasso N, De Pauw E.

Methods Mol Biol. 2018;1723:19-31. doi: 10.1007/978-1-4939-7558-7_2.

PMID:
29344853
23.

Reaction Product Variability and Biological Activity of the Lactoperoxidase System Depending on Medium Ionic Strength and pH, and on Substrate Relative Concentration.

Bafort F, Damblon C, Smargiasso N, De Pauw E, Perraudin JP, Jijakli MH.

Chem Biodivers. 2018 Mar;15(3):e1700497. doi: 10.1002/cbdv.201700497. Epub 2018 Mar 7.

PMID:
29266741
24.

Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases.

Blomme A, Van Simaeys G, Doumont G, Costanza B, Bellier J, Otaka Y, Sherer F, Lovinfosse P, Boutry S, Palacios AP, De Pauw E, Hirano T, Yokobori T, Hustinx R, Bellahcène A, Delvenne P, Detry O, Goldman S, Nishiyama M, Castronovo V, Turtoi A.

Oncogene. 2018 Mar;37(9):1237-1250. doi: 10.1038/s41388-017-0018-x. Epub 2017 Dec 15.

PMID:
29242606
25.

MALDI Imaging Combined with Laser Microdissection-Based Microproteomics for Protein Identification: Application to Intratumor Heterogeneity Studies.

Longuespée R, Alberts D, Baiwir D, Mazzucchelli G, Smargiasso N, De Pauw E.

Methods Mol Biol. 2018;1788:297-312. doi: 10.1007/7651_2017_114.

PMID:
29224050
26.

Physiological and proteomic responses to corticosteroid treatments in Eurasian perch, Perca fluviatilis: Investigation of immune-related parameters.

Milla S, Massart S, Mathieu C, Wang N, Douny C, Douxfils J, Scippo ML, De Pauw E, Dieu M, Silvestre F, Kestemont P.

Comp Biochem Physiol Part D Genomics Proteomics. 2018 Mar;25:86-98. doi: 10.1016/j.cbd.2017.11.005. Epub 2017 Dec 1.

PMID:
29223774
27.

In-Depth Glyco-Peptidomics Approach Reveals Unexpected Diversity of Glycosylated Peptides and Atypical Post-Translational Modifications in Dendroaspis angusticeps Snake Venom.

Degueldre M, Echterbille J, Smargiasso N, Damblon C, Gouin C, Mourier G, Gilles N, De Pauw E, Quinton L.

Int J Mol Sci. 2017 Nov 18;18(11). pii: E2453. doi: 10.3390/ijms18112453.

28.

Comprehensive Ion Mobility Calibration: Poly(ethylene oxide) Polymer Calibrants and General Strategies.

Haler JRN, Kune C, Massonnet P, Comby-Zerbino C, Jordens J, Honing M, Mengerink Y, Far J, De Pauw E.

Anal Chem. 2017 Nov 21;89(22):12076-12086. doi: 10.1021/acs.analchem.7b02564. Epub 2017 Nov 7.

PMID:
29064225
29.

Comparison of Different Ion Mobility Setups Using Poly (Ethylene Oxide) PEO Polymers: Drift Tube, TIMS, and T-Wave.

Haler JRN, Massonnet P, Chirot F, Kune C, Comby-Zerbino C, Jordens J, Honing M, Mengerink Y, Far J, Dugourd P, De Pauw E.

J Am Soc Mass Spectrom. 2018 Jan;29(1):114-120. doi: 10.1007/s13361-017-1822-9. Epub 2017 Oct 12.

PMID:
29027151
30.

Activity of the purified plant ABC transporter NtPDR1 is stimulated by diterpenes and sesquiterpenes involved in constitutive and induced defenses.

Pierman B, Toussaint F, Bertin A, Lévy D, Smargiasso N, De Pauw E, Boutry M.

J Biol Chem. 2017 Nov 24;292(47):19491-19502. doi: 10.1074/jbc.M117.811935. Epub 2017 Sep 29.

31.

Flying Cages in Traveling Wave Ion Mobility: Influence of the Instrumental Parameters on the Topology of the Host-Guest Complexes.

Carroy G, Lemaur V, Henoumont C, Laurent S, De Winter J, De Pauw E, Cornil J, Gerbaux P.

J Am Soc Mass Spectrom. 2018 Jan;29(1):121-132. doi: 10.1007/s13361-017-1816-7. Epub 2017 Oct 2.

PMID:
28971374
32.

Insights into the molecular basis of biocontrol of Brassica pathogens by Bacillus amyloliquefaciens UCMB5113 lipopeptides.

Asari S, Ongena M, Debois D, De Pauw E, Chen K, Bejai S, Meijer J.

Ann Bot. 2017 Oct 17;120(4):551-562. doi: 10.1093/aob/mcx089.

33.

APETx4, a Novel Sea Anemone Toxin and a Modulator of the Cancer-Relevant Potassium Channel KV10.1.

Moreels L, Peigneur S, Galan DT, De Pauw E, Béress L, Waelkens E, Pardo LA, Quinton L, Tytgat J.

Mar Drugs. 2017 Sep 13;15(9). pii: E287. doi: 10.3390/md15090287.

34.

Where Ion Mobility and Molecular Dynamics Meet To Unravel the (Un)Folding Mechanisms of an Oligorotaxane Molecular Switch.

Hanozin E, Mignolet B, Morsa D, Sluysmans D, Duwez AS, Stoddart JF, Remacle F, De Pauw E.

ACS Nano. 2017 Oct 24;11(10):10253-10263. doi: 10.1021/acsnano.7b04833. Epub 2017 Sep 13.

PMID:
28881131
35.

Multiple Gas-Phase Conformations of a Synthetic Linear Poly(acrylamide) Polymer Observed Using Ion Mobility-Mass Spectrometry.

Haler JRN, Far J, Aqil A, Claereboudt J, Tomczyk N, Giles K, Jérôme C, De Pauw E.

J Am Soc Mass Spectrom. 2017 Nov;28(11):2492-2499. doi: 10.1007/s13361-017-1769-x. Epub 2017 Aug 14.

PMID:
28808984
36.

MALDI Imaging-Guided Microproteomic Analyses of Heterogeneous Breast Tumors-A Pilot Study.

Alberts D, Pottier C, Smargiasso N, Baiwir D, Mazzucchelli G, Delvenne P, Kriegsmann M, Kazdal D, Warth A, De Pauw E, Longuespée R.

Proteomics Clin Appl. 2018 Jan;12(1). doi: 10.1002/prca.201700062. Epub 2017 Sep 15.

PMID:
28801933
37.

Safety effects of dynamic speed limits on motorways.

De Pauw E, Daniels S, Franckx L, Mayeres I.

Accid Anal Prev. 2018 May;114:83-89. doi: 10.1016/j.aap.2017.06.013. Epub 2017 Jul 4.

PMID:
28687120
38.

Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease.

Ciolek J, Reinfrank H, Quinton L, Viengchareun S, Stura EA, Vera L, Sigismeau S, Mouillac B, Orcel H, Peigneur S, Tytgat J, Droctové L, Beau F, Nevoux J, Lombès M, Mourier G, De Pauw E, Servent D, Mendre C, Witzgall R, Gilles N.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7154-7159. doi: 10.1073/pnas.1620454114. Epub 2017 Jun 19.

39.

Correction: Supramolecular influence on cis-trans isomerization probed by ion mobility spectrometry.

Czerwinska I, Kulesza A, Choi C, Chirot F, Simon AL, Far J, Kune C, de Pauw E, Dugourd P.

Phys Chem Chem Phys. 2017 Jun 14;19(23):15570. doi: 10.1039/c7cp90113e.

PMID:
28569908
40.

Importance of intellectual property generated by biomedical research at universities and academic hospitals.

Heus JJ, de Pauw ES, Mirjam L, Margherita M, Michael R H, Michal H.

J Clin Transl Res. 2017 May 24;3(2):250-259. eCollection 2017 May 24. Review.

41.

Inactivation of the β(1,2)-xylosyltransferase and the α(1,3)-fucosyltransferase genes in Nicotiana tabacum BY-2 Cells by a Multiplex CRISPR/Cas9 Strategy Results in Glycoproteins without Plant-Specific Glycans.

Mercx S, Smargiasso N, Chaumont F, De Pauw E, Boutry M, Navarre C.

Front Plant Sci. 2017 Mar 27;8:403. doi: 10.3389/fpls.2017.00403. eCollection 2017.

42.

Proteomic response of Macrobrachium rosenbergii hepatopancreas exposed to chlordecone: Identification of endocrine disruption biomarkers?

Lafontaine A, Baiwir D, Joaquim-Justo C, De Pauw E, Lemoine S, Boulangé-Lecomte C, Forget-Leray J, Thomé JP, Gismondi E.

Ecotoxicol Environ Saf. 2017 Jul;141:306-314. doi: 10.1016/j.ecoenv.2017.03.043. Epub 2017 Apr 6.

PMID:
28371731
43.

OLFM4, KNG1 and Sec24C identified by proteomics and immunohistochemistry as potential markers of early colorectal cancer stages.

Quesada-Calvo F, Massot C, Bertrand V, Longuespée R, Blétard N, Somja J, Mazzucchelli G, Smargiasso N, Baiwir D, De Pauw-Gillet MC, Delvenne P, Malaise M, Coimbra Marques C, Polus M, De Pauw E, Meuwis MA, Louis E.

Clin Proteomics. 2017 Mar 24;14:9. doi: 10.1186/s12014-017-9143-3. eCollection 2017.

44.

N-Glycosylation of an IgG antibody secreted by Nicotiana tabacum BY-2 cells can be modulated through co-expression of human β-1,4-galactosyltransferase.

Navarre C, Smargiasso N, Duvivier L, Nader J, Far J, De Pauw E, Boutry M.

Transgenic Res. 2017 Jun;26(3):375-384. doi: 10.1007/s11248-017-0013-6. Epub 2017 Mar 22.

PMID:
28332009
45.

Ecotoxicoproteomic assessment of the functional alterations caused by chronic metallic exposures in gammarids.

Gismondi E, Thomé JP, Urien N, Uher E, Baiwir D, Mazzucchelli G, De Pauw E, Fechner LC, Lebrun JD.

Environ Pollut. 2017 Jun;225:428-438. doi: 10.1016/j.envpol.2017.03.006. Epub 2017 Mar 9.

PMID:
28285888
46.

Discovery and characterization of EIIB, a new α-conotoxin from Conus ermineus venom by nAChRs affinity capture monitored by MALDI-TOF/TOF mass spectrometry.

Echterbille J, Gilles N, Araóz R, Mourier G, Amar M, Servent D, De Pauw E, Quinton L.

Toxicon. 2017 May;130:1-10. doi: 10.1016/j.toxicon.2017.02.023. Epub 2017 Feb 24.

PMID:
28238803
47.

Diversity in sequences, post-translational modifications and expected pharmacological activities of toxins from four Conus species revealed by the combination of cutting-edge proteomics, transcriptomics and bioinformatics.

Degueldre M, Verdenaud M, Legarda G, Minambres R, Zuniga S, Leblanc M, Gilles N, Ducancel F, De Pauw E, Quinton L.

Toxicon. 2017 May;130:116-125. doi: 10.1016/j.toxicon.2017.02.014. Epub 2017 Feb 20.

PMID:
28223047
48.

Identification of proteins from wild cardoon flowers (Cynara cardunculus L.) by a proteomic approach.

Ben Amira A, Bauwens J, De Pauw E, Besbes S, Attia H, Francis F, Blecker C.

J Chem Biol. 2016 Oct 25;10(1):25-33. doi: 10.1007/s12154-016-0161-9. eCollection 2017 Jan.

49.

High-throughput expression of animal venom toxins in Escherichia coli to generate a large library of oxidized disulphide-reticulated peptides for drug discovery.

Turchetto J, Sequeira AF, Ramond L, Peysson F, Brás JL, Saez NJ, Duhoo Y, Blémont M, Guerreiro CI, Quinton L, De Pauw E, Gilles N, Darbon H, Fontes CM, Vincentelli R.

Microb Cell Fact. 2017 Jan 17;16(1):6. doi: 10.1186/s12934-016-0617-1.

50.

Importance of intellectual property generated by biomedical research at universities and academic hospitals.

Heus JJ, de Pauw ES, Leloux M, Morpurgo M, Hamblin MR, Heger M.

J Clin Transl Res. 2017;3(2). pii: 5. doi: 10.18053/jctres.03.201702.005. Epub 2017 May 24.

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