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Items: 23


Nestin affects fusion pore dynamics in mouse astrocytes.

Lasič E, Trkov Bobnar S, Wilhelmsson U, de Pablo Y, Pekny M, Zorec R, Stenovec M.

Acta Physiol (Oxf). 2019 Oct 9:e13399. doi: 10.1111/apha.13399. [Epub ahead of print]


Vimentin Phosphorylation Is Required for Normal Cell Division of Immature Astrocytes.

de Pablo Y, Marasek P, Pozo-Rodrigálvarez A, Wilhelmsson U, Inagaki M, Pekna M, Pekny M.

Cells. 2019 Sep 1;8(9). pii: E1016. doi: 10.3390/cells8091016.


The role of GFAP and vimentin in learning and memory.

Wilhelmsson U, Pozo-Rodrigalvarez A, Kalm M, de Pablo Y, Widestrand Å, Pekna M, Pekny M.

Biol Chem. 2019 Aug 27;400(9):1147-1156. doi: 10.1515/hsz-2019-0199.


The cysteine residue of glial fibrillary acidic protein is a critical target for lipoxidation and required for efficient network organization.

Viedma-Poyatos Á, de Pablo Y, Pekny M, Pérez-Sala D.

Free Radic Biol Med. 2018 May 20;120:380-394. doi: 10.1016/j.freeradbiomed.2018.04.007. Epub 2018 Apr 7.


Injury Leads to the Appearance of Cells with Characteristics of Both Microglia and Astrocytes in Mouse and Human Brain.

Wilhelmsson U, Andersson D, de Pablo Y, Pekny R, Ståhlberg A, Mulder J, Mitsios N, Hortobágyi T, Pekny M, Pekna M.

Cereb Cortex. 2017 Jun 1;27(6):3360-3377. doi: 10.1093/cercor/bhx069.


Drugs targeting intermediate filaments can improve neurosupportive properties of astrocytes.

de Pablo Y, Chen M, Möllerström E, Pekna M, Pekny M.

Brain Res Bull. 2018 Jan;136:130-138. doi: 10.1016/j.brainresbull.2017.01.021. Epub 2017 Jan 31.


Complement Peptide C3a Promotes Astrocyte Survival in Response to Ischemic Stress.

Shinjyo N, de Pablo Y, Pekny M, Pekna M.

Mol Neurobiol. 2016 Jul;53(5):3076-3087. doi: 10.1007/s12035-015-9204-4. Epub 2015 May 14.


HB-EGF affects astrocyte morphology, proliferation, differentiation, and the expression of intermediate filament proteins.

Puschmann TB, Zandén C, Lebkuechner I, Philippot C, de Pablo Y, Liu J, Pekny M.

J Neurochem. 2014 Mar;128(6):878-89. doi: 10.1111/jnc.12519. Epub 2013 Nov 26.


A novel method for three-dimensional culture of central nervous system neurons.

Puschmann TB, de Pablo Y, Zandén C, Liu J, Pekny M.

Tissue Eng Part C Methods. 2014 Jun;20(6):485-92. doi: 10.1089/ten.TEC.2013.0445. Epub 2014 Jan 8.


Intermediate filaments are important for astrocyte response to oxidative stress induced by oxygen-glucose deprivation and reperfusion.

de Pablo Y, Nilsson M, Pekna M, Pekny M.

Histochem Cell Biol. 2013 Jul;140(1):81-91. doi: 10.1007/s00418-013-1110-0. Epub 2013 Jun 12.


Bioactive 3D cell culture system minimizes cellular stress and maintains the in vivo-like morphological complexity of astroglial cells.

Puschmann TB, Zandén C, De Pablo Y, Kirchhoff F, Pekna M, Liu J, Pekny M.

Glia. 2013 Mar;61(3):432-40. doi: 10.1002/glia.22446. Epub 2013 Jan 7.


Astrocytes negatively regulate neurogenesis through the Jagged1-mediated Notch pathway.

Wilhelmsson U, Faiz M, de Pablo Y, Sjöqvist M, Andersson D, Widestrand A, Potokar M, Stenovec M, Smith PL, Shinjyo N, Pekny T, Zorec R, Ståhlberg A, Pekna M, Sahlgren C, Pekny M.

Stem Cells. 2012 Oct;30(10):2320-9. doi: 10.1002/stem.1196.


IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments.

Vardjan N, Gabrijel M, Potokar M, Svajger U, Kreft M, Jeras M, de Pablo Y, Faiz M, Pekny M, Zorec R.

J Neuroinflammation. 2012 Jun 26;9:144. doi: 10.1186/1742-2094-9-144.


PHLDA1 is a crucial negative regulator and effector of Aurora A kinase in breast cancer.

Johnson EO, Chang KH, de Pablo Y, Ghosh S, Mehta R, Badve S, Shah K.

J Cell Sci. 2011 Aug 15;124(Pt 16):2711-22. doi: 10.1242/jcs.084970.


Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death.

Chang KH, Multani PS, Sun KH, Vincent F, de Pablo Y, Ghosh S, Gupta R, Lee HP, Lee HG, Smith MA, Shah K.

Mol Biol Cell. 2011 May;22(9):1452-62. doi: 10.1091/mbc.E10-07-0654. Epub 2011 Mar 9.


Ubiquitination of TrkA by Nedd4-2 regulates receptor lysosomal targeting and mediates receptor signaling.

Georgieva MV, de Pablo Y, Sanchis D, Comella JX, Llovera M.

J Neurochem. 2011 May;117(3):479-93. doi: 10.1111/j.1471-4159.2011.07218.x. Epub 2011 Mar 15.


Cdk5 is a major regulator of p38 cascade: relevance to neurotoxicity in Alzheimer's disease.

Chang KH, de Pablo Y, Lee HP, Lee HG, Smith MA, Shah K.

J Neurochem. 2010 Jun;113(5):1221-9. doi: 10.1111/j.1471-4159.2010.06687.x. Epub 2010 Mar 14.


Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction.

Sun KH, de Pablo Y, Vincent F, Shah K.

J Neurochem. 2008 Oct;107(1):265-78. doi: 10.1111/j.1471-4159.2008.05616.x. Epub 2008 Aug 9.


Novel genetic tools reveal Cdk5's major role in Golgi fragmentation in Alzheimer's disease.

Sun KH, de Pablo Y, Vincent F, Johnson EO, Chavers AK, Shah K.

Mol Biol Cell. 2008 Jul;19(7):3052-69. doi: 10.1091/mbc.E07-11-1106. Epub 2008 May 14.


Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function.

de Pablo Y, Pérez-García MJ, Georgieva MV, Sanchis D, Lindqvist N, Soler RM, Comella JX, Llovera M.

J Neurochem. 2008 Jan;104(1):124-39. doi: 10.1111/j.1471-4159.2007.05027.x.


Neuroprotection by neurotrophic factors and membrane depolarization is regulated by calmodulin kinase IV.

Pérez-García MJ, Gou-Fabregas M, de Pablo Y, Llovera M, Comella JX, Soler RM.

J Biol Chem. 2008 Feb 15;283(7):4133-44. Epub 2007 Dec 13.


Trk is a calmodulin-binding protein: implications for receptor processing.

Llovera M, de Pablo Y, Egea J, Encinas M, Peiró S, Martín-Zanca D, Rocamora N, Comella JX.

J Neurochem. 2004 Jan;88(2):422-33.


Glial cell line-derived neurotrophic factor increases intracellular calcium concentration. Role of calcium/calmodulin in the activation of the phosphatidylinositol 3-kinase pathway.

Pérez-García MJ, Ceña V, de Pablo Y, Llovera M, Comella JX, Soler RM.

J Biol Chem. 2004 Feb 13;279(7):6132-42. Epub 2003 Nov 20.

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