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Items: 1 to 50 of 132

1.

Poly(ADP-ribose) polymerase 2 contributes to neuroinflammation and neurological dysfunction in mouse experimental autoimmune encephalomyelitis.

Kamboj A, Lu P, Cossoy MB, Stobart JL, Dolhun BA, Kauppinen TM, de Murcia G, Anderson CM.

J Neuroinflammation. 2013 Apr 22;10:49. doi: 10.1186/1742-2094-10-49.

2.

Radiation-induced mitotic catastrophe in PARG-deficient cells.

Amé JC, Fouquerel E, Gauthier LR, Biard D, Boussin FD, Dantzer F, de Murcia G, Schreiber V.

J Cell Sci. 2009 Jun 15;122(Pt 12):1990-2002. doi: 10.1242/jcs.039115. Epub 2009 May 19.

3.

XRCC1 interacts with the p58 subunit of DNA Pol alpha-primase and may coordinate DNA repair and replication during S phase.

Lévy N, Oehlmann M, Delalande F, Nasheuer HP, Van Dorsselaer A, Schreiber V, de Murcia G, Ménissier-de Murcia J, Maiorano D, Bresson A.

Nucleic Acids Res. 2009 Jun;37(10):3177-88. doi: 10.1093/nar/gkp144. Epub 2009 Mar 21.

4.

PARP-1 is involved in autophagy induced by DNA damage.

Muñoz-Gámez JA, Rodríguez-Vargas JM, Quiles-Pérez R, Aguilar-Quesada R, Martín-Oliva D, de Murcia G, Menissier de Murcia J, Almendros A, Ruiz de Almodóvar M, Oliver FJ.

Autophagy. 2009 Jan;5(1):61-74. Epub 2009 Jan 27.

PMID:
19001878
5.

Poly(ADP-ribose) polymerase-2 [corrected] controls adipocyte differentiation and adipose tissue function through the regulation of the activity of the retinoid X receptor/peroxisome proliferator-activated receptor-gamma [corrected] heterodimer.

Bai P, Houten SM, Huber A, Schreiber V, Watanabe M, Kiss B, de Murcia G, Auwerx J, Ménissier-de Murcia J.

J Biol Chem. 2007 Dec 28;282(52):37738-46. Epub 2007 Oct 19. Erratum in: J Biol Chem. 2008 Feb 29;283(9):5972.

6.

Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition.

Aguilar-Quesada R, Muñoz-Gámez JA, Martín-Oliva D, Peralta A, Valenzuela MT, Matínez-Romero R, Quiles-Pérez R, Menissier-de Murcia J, de Murcia G, Ruiz de Almodóvar M, Oliver FJ.

BMC Mol Biol. 2007 Apr 25;8:29.

7.

A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance.

Gueven N, Becherel OJ, Howe O, Chen P, Haince JF, Ouellet ME, Poirier GG, Waterhouse N, Fusser M, Epe B, de Murcia JM, de Murcia G, McGowan CH, Parton R, Mothersill C, Grattan-Smith P, Lavin MF.

Cell Death Differ. 2007 Jun;14(6):1149-61. Epub 2007 Mar 9.

8.

Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis.

Dantzer F, Mark M, Quenet D, Scherthan H, Huber A, Liebe B, Monaco L, Chicheportiche A, Sassone-Corsi P, de Murcia G, Ménissier-de Murcia J.

Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14854-9. Epub 2006 Sep 25.

9.

PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes.

Yélamos J, Monreal Y, Saenz L, Aguado E, Schreiber V, Mota R, Fuente T, Minguela A, Parrilla P, de Murcia G, Almarza E, Aparicio P, Ménissier-de Murcia J.

EMBO J. 2006 Sep 20;25(18):4350-60. Epub 2006 Aug 31.

10.

Poly(ADP-ribose): novel functions for an old molecule.

Schreiber V, Dantzer F, Ame JC, de Murcia G.

Nat Rev Mol Cell Biol. 2006 Jul;7(7):517-28. Review.

PMID:
16829982
11.

Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair.

Dantzer F, Amé JC, Schreiber V, Nakamura J, Ménissier-de Murcia J, de Murcia G.

Methods Enzymol. 2006;409:493-510.

PMID:
16793420
12.

Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage.

Kolthur-Seetharam U, Dantzer F, McBurney MW, de Murcia G, Sassone-Corsi P.

Cell Cycle. 2006 Apr;5(8):873-7. Epub 2006 Apr 17.

PMID:
16628003
13.

Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells.

Hochegger H, Dejsuphong D, Fukushima T, Morrison C, Sonoda E, Schreiber V, Zhao GY, Saberi A, Masutani M, Adachi N, Koyama H, de Murcia G, Takeda S.

EMBO J. 2006 Mar 22;25(6):1305-14. Epub 2006 Feb 23.

14.

XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage.

Lévy N, Martz A, Bresson A, Spenlehauer C, de Murcia G, Ménissier-de Murcia J.

Nucleic Acids Res. 2006 Jan 5;34(1):32-41. Print 2006.

15.

DNA-induced dimerization of poly(ADP-ribose) polymerase-1 triggers its activation.

Pion E, Ullmann GM, Amé JC, Gérard D, de Murcia G, Bombarda E.

Biochemistry. 2005 Nov 8;44(44):14670-81.

PMID:
16262266
16.

Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage.

Monaco L, Kolthur-Seetharam U, Loury R, Murcia JM, de Murcia G, Sassone-Corsi P.

Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14244-8. Epub 2005 Sep 22.

17.

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator.

Pavri R, Lewis B, Kim TK, Dilworth FJ, Erdjument-Bromage H, Tempst P, de Murcia G, Evans R, Chambon P, Reinberg D.

Mol Cell. 2005 Apr 1;18(1):83-96.

18.

Establishment of an immortalized PARP-1-/- murine endothelial cell line: a new tool to study PARP-1 mediated endothelial cell dysfunction.

Carrillo A, Monreal Y, Ramirez P, Suarez E, Parrilla P, Menissier-de Murcia J, de Murcia G, Alvarez-Vallina L, Yélamos J.

J Cell Biochem. 2005 Apr 15;94(6):1163-74.

PMID:
15696577
19.

PARP-1 and PARP-2 interact with nucleophosmin/B23 and accumulate in transcriptionally active nucleoli.

Meder VS, Boeglin M, de Murcia G, Schreiber V.

J Cell Sci. 2005 Jan 1;118(Pt 1):211-22.

20.

Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs.

Espejel S, Klatt P, Ménissier-de Murcia J, Martín-Caballero J, Flores JM, Taccioli G, de Murcia G, Blasco MA.

J Cell Biol. 2004 Nov 22;167(4):627-38. Epub 2004 Nov 15.

21.

PARP inhibition sensitizes p53-deficient breast cancer cells to doxorubicin-induced apoptosis.

Muñoz-Gámez JA, Martín-Oliva D, Aguilar-Quesada R, Cañuelo A, Nuñez MI, Valenzuela MT, Ruiz de Almodóvar JM, De Murcia G, Oliver FJ.

Biochem J. 2005 Feb 15;386(Pt 1):119-25.

22.

PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development.

Huber A, Bai P, de Murcia JM, de Murcia G.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):1103-8. Review.

PMID:
15279798
23.

The PARP superfamily.

Amé JC, Spenlehauer C, de Murcia G.

Bioessays. 2004 Aug;26(8):882-93. Review.

PMID:
15273990
24.

Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2.

Dantzer F, Giraud-Panis MJ, Jaco I, Amé JC, Schultz I, Blasco M, Koering CE, Gilson E, Ménissier-de Murcia J, de Murcia G, Schreiber V.

Mol Cell Biol. 2004 Feb;24(4):1595-607.

25.

Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2.

Oliver AW, Amé JC, Roe SM, Good V, de Murcia G, Pearl LH.

Nucleic Acids Res. 2004 Jan 22;32(2):456-64. Print 2004.

26.

Poly(ADP-ribose) polymerase-1 is a survival factor for radiation-exposed intestinal epithelial stem cells in vivo.

Ishizuka S, Martin K, Booth C, Potten CS, de Murcia G, Bürkle A, Kirkwood TB.

Nucleic Acids Res. 2003 Nov 1;31(21):6198-205.

27.

Poly(ADP-ribose) polymerase-1 dimerizes at a 5' recessed DNA end in vitro: a fluorescence study.

Pion E, Bombarda E, Stiegler P, Ullmann GM, Mély Y, de Murcia G, Gérard D.

Biochemistry. 2003 Oct 28;42(42):12409-17.

PMID:
14567702
28.

Local DNA damage by proton microbeam irradiation induces poly(ADP-ribose) synthesis in mammalian cells.

Tartier L, Spenlehauer C, Newman HC, Folkard M, Prise KM, Michael BD, Ménissier-de Murcia J, de Murcia G.

Mutagenesis. 2003 Sep;18(5):411-6.

PMID:
12960408
29.

Role of XRCC1 in the coordination and stimulation of oxidative DNA damage repair initiated by the DNA glycosylase hOGG1.

Marsin S, Vidal AE, Sossou M, Ménissier-de Murcia J, Le Page F, Boiteux S, de Murcia G, Radicella JP.

J Biol Chem. 2003 Nov 7;278(45):44068-74. Epub 2003 Aug 21.

30.

Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time.

Nakamura J, Asakura S, Hester SD, de Murcia G, Caldecott KW, Swenberg JA.

Nucleic Acids Res. 2003 Sep 1;31(17):e104.

31.

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse.

Ménissier de Murcia J, Ricoul M, Tartier L, Niedergang C, Huber A, Dantzer F, Schreiber V, Amé JC, Dierich A, LeMeur M, Sabatier L, Chambon P, de Murcia G.

EMBO J. 2003 May 1;22(9):2255-63.

32.

PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression.

Augustin A, Spenlehauer C, Dumond H, Ménissier-De Murcia J, Piel M, Schmit AC, Apiou F, Vonesch JL, Kock M, Bornens M, De Murcia G.

J Cell Sci. 2003 Apr 15;116(Pt 8):1551-62.

33.

Poly(ADP-ribose) polymerase-1 (PARP-1) is required in murine cell lines for base excision repair of oxidative DNA damage in the absence of DNA polymerase beta.

Le Page F, Schreiber V, Dherin C, De Murcia G, Boiteux S.

J Biol Chem. 2003 May 16;278(20):18471-7. Epub 2003 Mar 7.

34.

Lethality in PARP-1/Ku80 double mutant mice reveals physiological synergy during early embryogenesis.

Henrie MS, Kurimasa A, Burma S, Ménissier-de Murcia J, de Murcia G, Li GC, Chen DJ.

DNA Repair (Amst). 2003 Feb 3;2(2):151-8.

PMID:
12531386
35.

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1.

Schreiber V, Amé JC, Dollé P, Schultz I, Rinaldi B, Fraulob V, Ménissier-de Murcia J, de Murcia G.

J Biol Chem. 2002 Jun 21;277(25):23028-36. Epub 2002 Apr 10.

36.

p53 Activation by nitric oxide involves down-regulation of Mdm2.

Wang X, Michael D, de Murcia G, Oren M.

J Biol Chem. 2002 May 3;277(18):15697-702. Epub 2002 Feb 26.

37.

PARP-1 modifies the effectiveness of p53-mediated DNA damage response.

Valenzuela MT, Guerrero R, Núñez MI, Ruiz De Almodóvar JM, Sarker M, de Murcia G, Oliver FJ.

Oncogene. 2002 Feb 7;21(7):1108-16.

38.

Ionising radiation induces the expression of PARP-1 and PARP-2 genes in Arabidopsis.

Doucet-Chabeaud G, Godon C, Brutesco C, de Murcia G, Kazmaier M.

Mol Genet Genomics. 2001 Aug;265(6):954-63.

PMID:
11523787
39.

Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability.

Samper E, Goytisolo FA, Ménissier-de Murcia J, González-Suárez E, Cigudosa JC, de Murcia G, Blasco MA.

J Cell Biol. 2001 Jul 9;154(1):49-60.

40.

Loss of poly(ADP-ribose) polymerase-1 causes increased tumour latency in p53-deficient mice.

Conde C, Mark M, Oliver FJ, Huber A, de Murcia G, Ménissier-de Murcia J.

EMBO J. 2001 Jul 2;20(13):3535-43.

41.

Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development.

Ménisser-de Murcia J, Mark M, Wendling O, Wynshaw-Boris A, de Murcia G.

Mol Cell Biol. 2001 Mar;21(5):1828-32.

42.

A bidirectional promoter connects the poly(ADP-ribose) polymerase 2 (PARP-2) gene to the gene for RNase P RNA. structure and expression of the mouse PARP-2 gene.

Ame JC, Schreiber V, Fraulob V, Dolle P, de Murcia G, Niedergang CP.

J Biol Chem. 2001 Apr 6;276(14):11092-9. Epub 2000 Dec 22.

43.

Poly(ADP-ribose) polymerase, a major determinant of early cell response to ionizing radiation.

Fernet M, Ponette V, Deniaud-Alexandre E, Ménissier-De Murcia J, De Murcia G, Giocanti N, Megnin-Chanet F, Favaudon V.

Int J Radiat Biol. 2000 Dec;76(12):1621-9.

PMID:
11133044
44.

Base excision repair is impaired in mammalian cells lacking Poly(ADP-ribose) polymerase-1.

Dantzer F, de La Rubia G, Ménissier-De Murcia J, Hostomsky Z, de Murcia G, Schreiber V.

Biochemistry. 2000 Jun 27;39(25):7559-69.

PMID:
10858306
45.

Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?

Shall S, de Murcia G.

Mutat Res. 2000 Jun 30;460(1):1-15. Review.

PMID:
10856830
46.

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice.

Oliver FJ, Ménissier-de Murcia J, Nacci C, Decker P, Andriantsitohaina R, Muller S, de la Rubia G, Stoclet JC, de Murcia G.

EMBO J. 1999 Aug 16;18(16):4446-54.

47.
48.

PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase.

Amé JC, Rolli V, Schreiber V, Niedergang C, Apiou F, Decker P, Muller S, Höger T, Ménissier-de Murcia J, de Murcia G.

J Biol Chem. 1999 Jun 18;274(25):17860-8.

49.
50.

A dual approach in the study of poly (ADP-ribose) polymerase: in vitro random mutagenesis and generation of deficient mice.

Trucco C, Rolli V, Oliver FJ, Flatter E, Masson M, Dantzer F, Niedergang C, Dutrillaux B, Ménissier-de Murcia J, de Murcia G.

Mol Cell Biochem. 1999 Mar;193(1-2):53-60.

PMID:
10331638

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