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Items: 1 to 50 of 77

1.

In silico analysis as a strategy to identify candidate epitopes with human IgG reactivity to study Porphyromonas gingivalis virulence factors.

Dos Santos-Lima EKN, Cardoso KAPA, de Miranda PM, Pimentel ACM, de Carvalho-Filho PC, de Oliveira YA, de Moura-Costa LF, Olczak T, Gomes-Filho IS, Meyer RJ, Xavier MT, Trindade SC.

AMB Express. 2019 Mar 11;9(1):35. doi: 10.1186/s13568-019-0757-x.

2.

In vivo and in vitro expression of five genes involved in Corynebacterium pseudotuberculosis virulence.

Corrêa JI, Stocker A, Trindade SC, Vale V, Brito T, Bastos B, Raynal JT, de Miranda PM, de Alcantara AC, Freire SM, Costa LM, Meyer R.

AMB Express. 2018 May 30;8(1):89. doi: 10.1186/s13568-018-0598-z.

3.

Contribution of the platelet activating factor signaling pathway to cerebral microcirculatory dysfunction during experimental sepsis by ExoU producing Pseudomonas aeruginosa.

Plotkowski MC, Estato V, Santos SA, da Silva MC, Miranda AS, de Miranda PE, Pinho V, Tibiriça E, Morandi V, Teixeira MM, Vianna A, Saliba AM.

Pathog Dis. 2015 Oct;73(7). pii: ftv046. doi: 10.1093/femspd/ftv046. Epub 2015 Jul 17.

4.

Hybrid approaches for interactive image segmentation using the live markers paradigm.

Spina TV, de Miranda PA, Falcão AX.

IEEE Trans Image Process. 2014 Dec;23(12):5756-69.

PMID:
25376038
5.

Anatomical and physiological changes in the venous system of lower limbs in pregnant women and findings associated with the symptomatology.

Goulart VB, Cabral AC, Reis ZS, Navarro TP, Alves SL, de Miranda PR, Sarquis AL, de Lima Rezende CA.

Arch Gynecol Obstet. 2013 Jul;288(1):73-8. doi: 10.1007/s00404-013-2728-9. Epub 2013 Feb 12.

PMID:
23400352
6.

"Evaluation of off-label recombinant activated factor VII for multiple indications in children" by Reiter et al.

de Miranda PA.

Clin Appl Thromb Hemost. 2008 Apr;14(2):247; author reply 247. doi: 10.1177/1076029607313895. No abstract available.

PMID:
18372280
7.

A cost evaluation of treatment alternatives for mild-to-moderate bleeding episodes in patients with haemophilia and inhibitors in Brazil.

Ozelo MC, Villaça PR, De Almeida JO, Bueno TM, De Miranda PA, Hart WM, Karamalis M.

Haemophilia. 2007 Sep;13(5):462-9.

PMID:
17880430
8.

Effects of leptin on intake of specific micro- and macronutrients in a woman with leptin gene deficiency studied off and on leptin at stable body weight.

Licinio J, Milane M, Thakur S, Whelan F, Yildiz BO, Delibasi T, de Miranda PB, Ozata M, Bolu E, Depaoli A, Wong ML.

Appetite. 2007 Nov;49(3):594-9. Epub 2007 Apr 6.

9.

Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults.

Licinio J, Caglayan S, Ozata M, Yildiz BO, de Miranda PB, O'Kirwan F, Whitby R, Liang L, Cohen P, Bhasin S, Krauss RM, Veldhuis JD, Wagner AJ, DePaoli AM, McCann SM, Wong ML.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4531-6. Epub 2004 Mar 9.

10.

The selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine. Reproduced from Proc. Natl. Acad. Sci. USA 74, 5716-5720 (1977)

Elion GB, Furman PA, Fyfe JA, de Miranda P, Beauchamp L, Schaeffer HJ.

Rev Med Virol. 1999 Jul;9(3):147-52; discussion 152-3. No abstract available.

PMID:
10479776
11.

Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats.

Ayers KM, Clive D, Tucker WE Jr, Hajian G, de Miranda P.

Fundam Appl Toxicol. 1996 Aug;32(2):148-58.

PMID:
8921318
12.

Nonclinical toxicology studies with zidovudine: reproductive toxicity studies in rats and rabbits.

Greene JA, Ayers KM, Tucker WE Jr, de Miranda P.

Fundam Appl Toxicol. 1996 Aug;32(2):140-7.

PMID:
8921317
13.

Nonclinical toxicology studies with zidovudine: acute, subacute, and chronic toxicity in rodents, dogs, and monkeys.

Ayers KM, Tucker WE Jr, Hajian G, De Miranda P.

Fundam Appl Toxicol. 1996 Aug;32(2):129-39.

PMID:
8921316
14.

Valacyclovir HCl (Valtrex): an acyclovir prodrug with improved pharmacokinetics and better efficacy for treatment of zoster.

Smiley ML, Murray A, de Miranda P.

Adv Exp Med Biol. 1996;394:33-9. Review. No abstract available.

PMID:
8815698
15.

Metabolism and pharmacokinetics of a double prodrug of ganciclovir in the rat and monkey.

Krasny HC, Beauchamp L, Krenitsky TA, de Miranda P.

Drug Metab Dispos. 1995 Nov;23(11):1242-7.

PMID:
8591725
16.

Purification and characterization of a rat liver enzyme that hydrolyzes valaciclovir, the L-valyl ester prodrug of acyclovir.

Burnette TC, Harrington JA, Reardon JE, Merrill BM, de Miranda P.

J Biol Chem. 1995 Jun 30;270(26):15827-31.

17.

Metabolic disposition of the acyclovir prodrug valaciclovir in the rat.

Burnette TC, de Miranda P.

Drug Metab Dispos. 1994 Jan-Feb;22(1):60-4.

PMID:
8149891
18.

Metabolic fate and pharmacokinetics of the acyclovir prodrug valaciclovir in cynomolgus monkeys.

de Miranda P, Burnette TC.

Drug Metab Dispos. 1994 Jan-Feb;22(1):55-9.

PMID:
8149890
19.

Pharmacokinetics of the acyclovir pro-drug valaciclovir after escalating single- and multiple-dose administration to normal volunteers.

Weller S, Blum MR, Doucette M, Burnette T, Cederberg DM, de Miranda P, Smiley ML.

Clin Pharmacol Ther. 1993 Dec;54(6):595-605.

PMID:
8275615
20.

Review of research leading to new anti-herpesvirus agents in clinical development: valaciclovir hydrochloride (256U, the L-valyl ester of acyclovir) and 882C, a specific agent for varicella zoster virus.

Purifoy DJ, Beauchamp LM, de Miranda P, Ertl P, Lacey S, Roberts G, Rahim SG, Darby G, Krenitsky TA, Powell KL.

J Med Virol. 1993;Suppl 1:139-45. Review.

PMID:
8245881
21.

Di- and triester prodrugs of the varicella-zoster antiviral agent 6-methoxypurine arabinoside.

Jones LA, Moorman AR, Chamberlain SD, de Miranda P, Reynolds DJ, Burns CL, Krenitsky TA.

J Med Chem. 1992 Jan;35(1):56-63.

PMID:
1732533
22.

Selective anabolism of 6-methoxypurine arabinoside in varicella-zoster virus-infected cells.

Biron KK, de Miranda P, Burnette TC, Krenitsky TA.

Antimicrob Agents Chemother. 1991 Oct;35(10):2116-20.

23.

Anabolic pathway of 6-methoxypurine arabinoside in cells infected with varicella-zoster virus.

de Miranda P, Burnette TC, Biron KK, Miller RL, Averett DR, Krenitsky TA.

Antimicrob Agents Chemother. 1991 Oct;35(10):2121-4.

24.

Metabolic disposition and pharmacokinetics of the antiviral agent 6-methoxypurine arabinoside in rats and monkeys.

Burnette TC, Koszalka GW, Krenitsky TA, De Miranda P.

Antimicrob Agents Chemother. 1991 Jun;35(6):1165-73.

25.

Postnatal survival in Wistar rats following oral dosage with zidovudine on gestation day 10.

Greene JA, Ayers KM, de Miranda P, Tucker WE Jr.

Fundam Appl Toxicol. 1990 Jul;15(1):201-6.

PMID:
2373299
26.

Isolation and characterization of an ether glucuronide of zidovudine, a major metabolite in monkeys and humans.

Good SS, Koble CS, Crouch R, Johnson RL, Rideout JL, de Miranda P.

Drug Metab Dispos. 1990 May-Jun;18(3):321-6.

PMID:
1974193
27.

Tissue distribution and metabolic disposition of zidovudine in rats.

de Miranda P, Burnette TC, Good SS.

Drug Metab Dispos. 1990 May-Jun;18(3):315-20.

PMID:
1974192
28.

Alteration of zidovudine pharmacokinetics by probenecid in patients with AIDS or AIDS-related complex.

de Miranda P, Good SS, Yarchoan R, Thomas RV, Blum MR, Myers CE, Broder S.

Clin Pharmacol Ther. 1989 Nov;46(5):494-500.

PMID:
2582706
29.

Azidothymidine steady-state pharmacokinetics in patients with AIDS and AIDS-related complex.

Laskin OL, de Miranda P, Blum MR.

J Infect Dis. 1989 Apr;159(4):745-7. No abstract available.

PMID:
2926164
30.

Simultaneous quantification of zidovudine and its glucuronide in serum by high-performance liquid chromatography.

Good SS, Reynolds DJ, de Miranda P.

J Chromatogr. 1988 Sep 23;431(1):123-33.

PMID:
3235523
31.

Pharmacokinetics and bioavailability of zidovudine in humans.

Blum MR, Liao SH, Good SS, de Miranda P.

Am J Med. 1988 Aug 29;85(2A):189-94.

PMID:
3165603
32.

Prolonged pancytopenia due to combined ganciclovir and zidovudine therapy.

Jacobson MA, de Miranda P, Gordon SM, Blum MR, Volberding P, Mills J.

J Infect Dis. 1988 Aug;158(2):489-90. No abstract available.

PMID:
3261316
33.

Zidovudine overdosage.

Spear JB, Kessler HA, Lehrman SN, de Miranda P.

Ann Intern Med. 1988 Jul 1;109(1):76-7. No abstract available.

PMID:
3163905
34.

Concurrent zidovudine levels in semen and serum determined by radioimmunoassay in patients with AIDS or AIDS-related complex.

Henry K, Chinnock BJ, Quinn RP, Fletcher CV, de Miranda P, Balfour HH Jr.

JAMA. 1988 May 27;259(20):3023-6.

PMID:
3163381
35.

Acyclovir in human breast milk.

Meyer LJ, de Miranda P, Sheth N, Spruance S.

Am J Obstet Gynecol. 1988 Mar;158(3 Pt 1):586-8.

PMID:
3348321
36.

Human pharmacokinetics and tolerance of oral ganciclovir.

Jacobson MA, de Miranda P, Cederberg DM, Burnette T, Cobb E, Brodie HR, Mills J.

Antimicrob Agents Chemother. 1987 Aug;31(8):1251-4.

37.

BW B759U for cytomegalovirus retinitis: intraocular drug penetration.

Jabs DA, Wingard JR, de Bustros S, de Miranda P, Saral R, Santos GW.

Arch Ophthalmol. 1986 Oct;104(10):1436-7. No abstract available.

PMID:
3021090
38.

Human pharmacokinetics of the antiviral drug DHPG.

Fletcher C, Sawchuk R, Chinnock B, de Miranda P, Balfour HH Jr.

Clin Pharmacol Ther. 1986 Sep;40(3):281-6.

PMID:
3017630
39.

Intraocular 9-([2-hydroxy-1-(hydroxymethyl) ethoxy] methyl) guanine levels after intravitreal and subconjunctival administration.

Schulman J, Peyman GA, Horton MB, Liu J, Fiscella R, Pulido J, Barber JC, de Miranda P.

Ophthalmic Surg. 1986 Jul;17(7):429-32.

PMID:
3014412
40.

Intraocular acyclovir levels after subconjunctival and topical administration.

Schulman J, Peyman GA, Fiscella R, Greenberg D, Horton MB, de Miranda P.

Br J Ophthalmol. 1986 Feb;70(2):138-40.

41.

Intraocular penetration of new antiviral agent, hydroxyacyclovir (BW-B759U).

Schulman J, Peyman GA, Horton MB, Liu J, Barber JC, Fiscella R, de Miranda P.

Jpn J Ophthalmol. 1986;30(1):116-24.

PMID:
3014189
42.

Treatment of cytomegalovirus retinitis with 9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine.

Felsenstein D, D'Amico DJ, Hirsch MS, Neumeyer DA, Cederberg DM, de Miranda P, Schooley RT.

Ann Intern Med. 1985 Sep;103(3):377-80.

PMID:
2992334
43.

Activity of 9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine in the treatment of cytomegalovirus pneumonia.

Shepp DH, Dandliker PS, de Miranda P, Burnette TC, Cederberg DM, Kirk LE, Meyers JD.

Ann Intern Med. 1985 Sep;103(3):368-73.

PMID:
2992333
44.

6-Deoxyacyclovir: a xanthine oxidase-activated prodrug of acyclovir.

Krenitsky TA, Hall WW, de Miranda P, Beauchamp LM, Schaeffer HJ, Whiteman PD.

Proc Natl Acad Sci U S A. 1984 May;81(10):3209-13.

45.

Disposition in the dog and the rat of 2, 6-diamino-9-(2-hydroxyethoxymethyl)purine (A134U), a potential prodrug of acyclovir.

Good SS, Krasny HC, Elion GB, de Miranda P.

J Pharmacol Exp Ther. 1983 Dec;227(3):644-51.

PMID:
6655561
46.

Preclinical toxicology studies with acyclovir: carcinogenicity bioassays and chronic toxicity tests.

Tucker WE Jr, Krasny HC, de Miranda P, Goldenthal EI, Elion GB, Hajian G, Szczech GM.

Fundam Appl Toxicol. 1983 Nov-Dec;3(6):579-86.

PMID:
6662300
47.

Preclinical toxicology studies with acyclovir: acute and subchronic tests.

Tucker WE Jr, Macklin AW, Szot RJ, Johnston RE, Elion GB, de Miranda P, Szczech GM.

Fundam Appl Toxicol. 1983 Nov-Dec;3(6):573-8.

PMID:
6662299
48.

Preclinical toxicology studies with acyclovir: ophthalmic and cutaneous tests.

Tucker WE Jr, Johnston RE, Macklin AW, Szot RJ, Elion GB, de Miranda P, Szczech GM.

Fundam Appl Toxicol. 1983 Nov-Dec;3(6):569-72.

PMID:
6662298
49.

Preclinical toxicology studies with acyclovir: teratologic, reproductive and neonatal tests.

Moore HL Jr, Szczech GM, Rodwell DE, Kapp RW Jr, de Miranda P, Tucker WE Jr.

Fundam Appl Toxicol. 1983 Nov-Dec;3(6):560-8.

PMID:
6662297
50.

Pharmacokinetics of acyclovir after intravenous and oral administration.

de Miranda P, Blum MR.

J Antimicrob Chemother. 1983 Sep;12 Suppl B:29-37. Review.

PMID:
6355048

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