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Items: 1 to 50 of 120

1.

Membrane fluidity adjusts the insertion of the transacylase PlsX to regulate phospholipid biosynthesis in Gram-positive bacteria.

Sastre DE, Basso LGM, Trastoy B, Cifuente JO, Contreras X, Gueiros-Filho F, de Mendoza D, Navarro MVAS, Guerin ME.

J Biol Chem. 2019 Dec 3. pii: jbc.RA119.011122. doi: 10.1074/jbc.RA119.011122. [Epub ahead of print]

2.

Transmembrane Prolines Mediate Signal Sensing and Decoding in Bacillus subtilis DesK Histidine Kinase.

Fernández P, Porrini L, Albanesi D, Abriata LA, Dal Peraro M, de Mendoza D, Mansilla MC.

MBio. 2019 Nov 26;10(6). pii: e02564-19. doi: 10.1128/mBio.02564-19.

3.

Synthesis of a Deuterated Standard for the Quantification of 2-Arachidonoylglycerol in Caenorhabditis elegans.

Fernández de Luco J, Prez G, Hernández Cravero B, de Mendoza D, Labadie GR.

J Vis Exp. 2019 Sep 21;(151). doi: 10.3791/59882.

PMID:
31589209
4.

Control of membrane lipid homeostasis by lipid-bilayer associated sensors: A mechanism conserved from bacteria to humans.

de Mendoza D, Pilon M.

Prog Lipid Res. 2019 Oct;76:100996. doi: 10.1016/j.plipres.2019.100996. Epub 2019 Aug 23. Review.

PMID:
31449824
5.

A genetic screen for mutations affecting temperature sensing in Bacillus subtilis.

Díaz AR, Porrini L, de Mendoza D, Mansilla MC.

Microbiology. 2019 Jan;165(1):90-101. doi: 10.1099/mic.0.000741. Epub 2018 Nov 15.

PMID:
30431418
6.

Structural determinant of functionality in acyl lipid desaturases.

Sastre DE, Saita E, Uttaro AD, de Mendoza D, Altabe SG.

J Lipid Res. 2018 Oct;59(10):1871-1879. doi: 10.1194/jlr.M085258. Epub 2018 Aug 7.

7.

Endocannabinoids in Caenorhabditis elegans are essential for the mobilization of cholesterol from internal reserves.

Galles C, Prez GM, Penkov S, Boland S, Porta EOJ, Altabe SG, Labadie GR, Schmidt U, Knölker HJ, Kurzchalia TV, de Mendoza D.

Sci Rep. 2018 Apr 23;8(1):6398. doi: 10.1038/s41598-018-24925-8.

8.

Signal Sensing and Transduction by Histidine Kinases as Unveiled through Studies on a Temperature Sensor.

Abriata LA, Albanesi D, Dal Peraro M, de Mendoza D.

Acc Chem Res. 2017 Jun 20;50(6):1359-1366. doi: 10.1021/acs.accounts.6b00593. Epub 2017 May 5. Review.

PMID:
28475313
9.

The stringent response plays a key role in Bacillus subtilis survival of fatty acid starvation.

Pulschen AA, Sastre DE, Machinandiarena F, Crotta Asis A, Albanesi D, de Mendoza D, Gueiros-Filho FJ.

Mol Microbiol. 2017 Feb;103(4):698-712. doi: 10.1111/mmi.13582. Epub 2016 Dec 16.

10.

FapR: From Control of Membrane Lipid Homeostasis to a Biotechnological Tool.

Albanesi D, de Mendoza D.

Front Mol Biosci. 2016 Oct 6;3:64. eCollection 2016. Review.

11.

The Single Transmembrane Segment of Minimal Sensor DesK Senses Temperature via a Membrane-Thickness Caliper.

Inda ME, Oliveira RG, de Mendoza D, Cybulski LE.

J Bacteriol. 2016 Oct 7;198(21):2945-2954. Print 2016 Nov 1.

12.

Revisiting the cell biology of the acyl-ACP:phosphate transacylase PlsX suggests that the phospholipid synthesis and cell division machineries are not coupled in Bacillus subtilis.

Sastre DE, Bisson-Filho A, de Mendoza D, Gueiros-Filho FJ.

Mol Microbiol. 2016 May;100(4):621-34. doi: 10.1111/mmi.13337. Epub 2016 Mar 22.

13.

Sensing membrane thickness: Lessons learned from cold stress.

Saita E, Albanesi D, de Mendoza D.

Biochim Biophys Acta. 2016 Aug;1861(8 Pt B):837-846. doi: 10.1016/j.bbalip.2016.01.003. Epub 2016 Jan 8. Review.

PMID:
26776056
14.

A coiled coil switch mediates cold sensing by the thermosensory protein DesK.

Saita E, Abriata LA, Tsai YT, Trajtenberg F, Lemmin T, Buschiazzo A, Dal Peraro M, de Mendoza D, Albanesi D.

Mol Microbiol. 2015 Oct;98(2):258-71. doi: 10.1111/mmi.13118. Epub 2015 Aug 3.

15.

Activation of the bacterial thermosensor DesK involves a serine zipper dimerization motif that is modulated by bilayer thickness.

Cybulski LE, Ballering J, Moussatova A, Inda ME, Vazquez DB, Wassenaar TA, de Mendoza D, Tieleman DP, Killian JA.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):6353-8. doi: 10.1073/pnas.1422446112. Epub 2015 May 4.

16.

Thermosensing via transmembrane protein-lipid interactions.

Saita EA, de Mendoza D.

Biochim Biophys Acta. 2015 Sep;1848(9):1757-64. doi: 10.1016/j.bbamem.2015.04.005. Epub 2015 Apr 20. Review.

17.

Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.

Trajtenberg F, Albanesi D, Ruétalo N, Botti H, Mechaly AE, Nieves M, Aguilar PS, Cybulski L, Larrieux N, de Mendoza D, Buschiazzo A.

MBio. 2014 Nov 18;5(6):e02105. doi: 10.1128/mBio.02105-14.

18.

Using a microbial physiologic and genetic approach to investigate how bacteria sense physical stimuli.

Mussi MA, Actis LA, de Mendoza D, Cybulski LE.

Biochem Mol Biol Educ. 2014 Sep-Oct;42(5):427-34. doi: 10.1002/bmb.20810. Epub 2014 Jul 23.

19.

Temperature sensing by membranes.

de Mendoza D.

Annu Rev Microbiol. 2014;68:101-16. doi: 10.1146/annurev-micro-091313-103612. Epub 2014 May 7. Review.

PMID:
24819366
20.

Structural insights into bacterial resistance to cerulenin.

Trajtenberg F, Altabe S, Larrieux N, Ficarra F, de Mendoza D, Buschiazzo A, Schujman GE.

FEBS J. 2014 May;281(10):2324-38. doi: 10.1111/febs.12785. Epub 2014 Apr 9.

21.

Cerulenin inhibits unsaturated fatty acids synthesis in Bacillus subtilis by modifying the input signal of DesK thermosensor.

Porrini L, Cybulski LE, Altabe SG, Mansilla MC, de Mendoza D.

Microbiologyopen. 2014 Apr;3(2):213-24. doi: 10.1002/mbo3.154. Epub 2014 Feb 14.

22.

A lipid-mediated conformational switch modulates the thermosensing activity of DesK.

Inda ME, Vandenbranden M, Fernández A, de Mendoza D, Ruysschaert JM, Cybulski LE.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3579-84. doi: 10.1073/pnas.1317147111. Epub 2014 Feb 12.

23.

Peripheral venous blood gases and pulse-oximetry in acute cardiogenic pulmonary oedema.

Masip J, De Mendoza D, Planas K, Paez J, Sanchez B, Cancio B.

Eur Heart J Acute Cardiovasc Care. 2012 Dec;1(4):275-80. doi: 10.1177/2048872612457087.

24.

Exploring the biosynthesis of unsaturated fatty acids in Bacillus cereus ATCC 14579 and functional characterization of novel acyl-lipid desaturases.

Chazarreta Cifré L, Alemany M, de Mendoza D, Altabe S.

Appl Environ Microbiol. 2013 Oct;79(20):6271-9. doi: 10.1128/AEM.01761-13. Epub 2013 Aug 2.

25.

Regulation of Bacillus subtilis DesK thermosensor by lipids.

Martín M, de Mendoza D.

Biochem J. 2013 Apr 15;451(2):269-75. doi: 10.1042/BJ20121825.

PMID:
23356219
26.

Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus.

Albanesi D, Reh G, Guerin ME, Schaeffer F, Debarbouille M, Buschiazzo A, Schujman GE, de Mendoza D, Alzari PM.

PLoS Pathog. 2013 Jan;9(1):e1003108. doi: 10.1371/journal.ppat.1003108. Epub 2013 Jan 3.

27.

Vectorial signalling mechanism required for cell-cell communication during sporulation in Bacillus subtilis.

Diez V, Schujman GE, Gueiros-Filho FJ, de Mendoza D.

Mol Microbiol. 2012 Jan;83(2):261-74. doi: 10.1111/j.1365-2958.2011.07929.x. Epub 2011 Dec 7.

28.

Bilayer hydrophobic thickness and integral membrane protein function.

Cybulski LE, de Mendoza D.

Curr Protein Pept Sci. 2011 Dec;12(8):760-6. Review.

PMID:
22044142
29.

Thermal regulation of membrane lipid fluidity by a two-component system in Bacillus subtilis.

Bredeston LM, Marciano D, Albanesi D, De Mendoza D, Delfino JM.

Biochem Mol Biol Educ. 2011 Sep-Oct;39(5):362-6. doi: 10.1002/bmb.20510. Epub 2011 Jul 21.

30.

Role of ferredoxin and flavodoxins in Bacillus subtilis fatty acid desaturation.

Chazarreta-Cifre L, Martiarena L, de Mendoza D, Altabe SG.

J Bacteriol. 2011 Aug;193(16):4043-8. doi: 10.1128/JB.05103-11. Epub 2011 Jun 10.

31.

Oral immunization with live Lactococcus lactis expressing rotavirus VP8 subunit induces specific immune response in mice.

Marelli B, Perez AR, Banchio C, de Mendoza D, Magni C.

J Virol Methods. 2011 Jul;175(1):28-37. doi: 10.1016/j.jviromet.2011.04.011. Epub 2011 Apr 20.

PMID:
21530589
32.

Playing with transmembrane signals.

Cybulski LE, de Mendoza D.

Commun Integr Biol. 2011 Jan;4(1):69-71. doi: 10.4161/cib.4.1.13778.

33.

Serine/threonine protein kinase PrkA of the human pathogen Listeria monocytogenes: biochemical characterization and identification of interacting partners through proteomic approaches.

Lima A, Durán R, Schujman GE, Marchissio MJ, Portela MM, Obal G, Pritsch O, de Mendoza D, Cerveñansky C.

J Proteomics. 2011 Aug 24;74(9):1720-34. doi: 10.1016/j.jprot.2011.03.005. Epub 2011 Mar 23.

PMID:
21406257
34.

A novel amidotransferase required for lipoic acid cofactor assembly in Bacillus subtilis.

Christensen QH, Martin N, Mansilla MC, de Mendoza D, Cronan JE.

Mol Microbiol. 2011 Apr;80(2):350-63. doi: 10.1111/j.1365-2958.2011.07598.x. Epub 2011 Mar 17.

35.

A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesis.

Martin N, Christensen QH, Mansilla MC, Cronan JE, de Mendoza D.

Mol Microbiol. 2011 Apr;80(2):335-49. doi: 10.1111/j.1365-2958.2011.07597.x. Epub 2011 Mar 17.

36.

Membrane thickness cue for cold sensing in a bacterium.

Cybulski LE, Martín M, Mansilla MC, Fernández A, de Mendoza D.

Curr Biol. 2010 Sep 14;20(17):1539-44. doi: 10.1016/j.cub.2010.06.074. Epub 2010 Aug 12.

37.

Differences in cold adaptation of Bacillus subtilis under anaerobic and aerobic conditions.

Beranová J, Mansilla MC, de Mendoza D, Elhottová D, Konopásek I.

J Bacteriol. 2010 Aug;192(16):4164-71. doi: 10.1128/JB.00384-10. Epub 2010 Jun 25.

38.

A novel role of malonyl-ACP in lipid homeostasis.

Martinez MA, Zaballa ME, Schaeffer F, Bellinzoni M, Albanesi D, Schujman GE, Vila AJ, Alzari PM, de Mendoza D.

Biochemistry. 2010 Apr 13;49(14):3161-7. doi: 10.1021/bi100136n.

PMID:
20201588
39.

Transcriptional and functional characterization of the gene encoding acyl carrier protein in Bacillus subtilis.

Martinez MA, de Mendoza D, Schujman GE.

Microbiology. 2010 Feb;156(Pt 2):484-95. doi: 10.1099/mic.0.033316-0. Epub 2009 Oct 22.

PMID:
19850612
40.

A lipA (yutB) mutant, encoding lipoic acid synthase, provides insight into the interplay between branched-chain and unsaturated fatty acid biosynthesis in Bacillus subtilis.

Martin N, Lombardía E, Altabe SG, de Mendoza D, Mansilla MC.

J Bacteriol. 2009 Dec;191(24):7447-55. doi: 10.1128/JB.01160-09. Epub 2009 Oct 9.

41.

Structural plasticity and catalysis regulation of a thermosensor histidine kinase.

Albanesi D, Martín M, Trajtenberg F, Mansilla MC, Haouz A, Alzari PM, de Mendoza D, Buschiazzo A.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16185-90. doi: 10.1073/pnas.0906699106. Epub 2009 Sep 4.

42.

Oligomerization of Bacillus subtilis DesR is required for fine tuning regulation of membrane fluidity.

Najle SR, Inda ME, de Mendoza D, Cybulski LE.

Biochim Biophys Acta. 2009 Oct;1790(10):1238-43. doi: 10.1016/j.bbagen.2009.07.002. Epub 2009 Jul 9.

PMID:
19595746
43.

Functional in vitro assembly of the integral membrane bacterial thermosensor DesK.

Martín M, Albanesi D, Alzari PM, de Mendoza D.

Protein Expr Purif. 2009 Jul;66(1):39-45. doi: 10.1016/j.pep.2009.02.006. Epub 2009 Feb 20.

PMID:
19233289
44.

Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough.

Rodriguez A, Lisboa T, Blot S, Martin-Loeches I, Solé-Violan J, De Mendoza D, Rello J; Community-Acquired Pneumonia Intensive Care Units (CAPUCI) Study Investigators.

Intensive Care Med. 2009 Mar;35(3):430-8. doi: 10.1007/s00134-008-1363-6. Epub 2008 Dec 10.

PMID:
19066850
45.

Phosphatidylethanolamine synthesis is required for optimal virulence of Brucella abortus.

Bukata L, Altabe S, de Mendoza D, Ugalde RA, Comerci DJ.

J Bacteriol. 2008 Dec;190(24):8197-203. doi: 10.1128/JB.01069-08. Epub 2008 Oct 17.

46.

Signalling pathways controlling fatty acid desaturation.

Mansilla MC, Banchio CE, de Mendoza D.

Subcell Biochem. 2008;49:71-99. doi: 10.1007/978-1-4020-8831-5_3. Review.

PMID:
18751908
47.

Radiologic progression of pulmonary infiltrates predicts a worse prognosis in severe community-acquired pneumonia than bacteremia.

Lisboa T, Blot S, Waterer GW, Canalis E, de Mendoza D, Rodriguez A, Rello J.

Chest. 2009 Jan;135(1):165-172. doi: 10.1378/chest.08-1216. Epub 2008 Aug 8.

PMID:
18689575
48.

A malonyl-CoA-dependent switch in the bacterial response to a dysfunction of lipid metabolism.

Schujman GE, Altabe S, de Mendoza D.

Mol Microbiol. 2008 May;68(4):987-96. doi: 10.1111/j.1365-2958.2008.06202.x. Epub 2008 Apr 2.

49.

Regulation of type II fatty acid synthase in Gram-positive bacteria.

Schujman GE, de Mendoza D.

Curr Opin Microbiol. 2008 Apr;11(2):148-52. doi: 10.1016/j.mib.2008.02.002. Epub 2008 Mar 26. Review.

PMID:
18372209
50.

Isolation and characterization of unsaturated fatty acid auxotrophs of Streptococcus pneumoniae and Streptococcus mutans.

Altabe S, Lopez P, de Mendoza D.

J Bacteriol. 2007 Nov;189(22):8139-44. Epub 2007 Sep 7.

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