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Items: 1 to 50 of 99

1.

Protein Kinase C δ Regulates the Depletion of Actin at the Immunological Synapse Required for Polarized Exosome Secretion by T Cells.

Herranz G, Aguilera P, Dávila S, Sánchez A, Stancu B, Gómez J, Fernández-Moreno D, de Martín R, Quintanilla M, Fernández T, Rodríguez-Silvestre P, Márquez-Expósito L, Bello-Gamboa A, Fraile-Ramos A, Calvo V, Izquierdo M.

Front Immunol. 2019 Apr 26;10:851. doi: 10.3389/fimmu.2019.00851. eCollection 2019.

2.

A Symphytum officinale Root Extract Exerts Anti-inflammatory Properties by Affecting Two Distinct Steps of NF-κB Signaling.

Seigner J, Junker-Samek M, Plaza A, D'Urso G, Masullo M, Piacente S, Holper-Schichl YM, de Martin R.

Front Pharmacol. 2019 Apr 26;10:289. doi: 10.3389/fphar.2019.00289. eCollection 2019.

3.

FOXF1 Mediates Endothelial Progenitor Functions and Regulates Vascular Sprouting.

Sturtzel C, Lipnik K, Hofer-Warbinek R, Testori J, Ebner B, Seigner J, Qiu P, Bilban M, Jandrositz A, Preisegger KH, Untergasser G, Gunsilius E, de Martin R, Kroll J, Hofer E.

Front Bioeng Biotechnol. 2018 Jun 14;6:76. doi: 10.3389/fbioe.2018.00076. eCollection 2018.

4.

12(S)-HETE induces lymph endothelial cell retraction in vitro by upregulation of SOX18.

Fristiohady A, Milovanovic D, Krieger S, Huttary N, Nguyen CH, Basilio J, Jäger W, De Martin R, Krupitza G.

Int J Oncol. 2018 Jul;53(1):307-316. doi: 10.3892/ijo.2018.4378. Epub 2018 Apr 26.

PMID:
29749465
5.

Matrix Metalloproteinase-2 Impairs Homing of Intracoronary Delivered Mesenchymal Stem Cells in a Porcine Reperfused Myocardial Infarction: Comparison With Intramyocardial Cell Delivery.

Zlabinger K, Lukovic D, Hemetsberger R, Gugerell A, Winkler J, Mandic L, Traxler D, Spannbauer A, Wolbank S, Zanoni G, Kaun C, Posa A, Gyenes A, Petrasi Z, Petnehazy Ö, Repa I, Hofer-Warbinek R, de Martin R, Gruber F, Charwat S, Huber K, Pavo N, Pavo IJ, Nyolczas N, Kraitchman DL, Gyöngyösi M.

Front Bioeng Biotechnol. 2018 Apr 4;6:35. doi: 10.3389/fbioe.2018.00035. eCollection 2018.

6.

Self-medication by orang-utans (Pongo pygmaeus) using bioactive properties of Dracaena cantleyi.

Morrogh-Bernard HC, Foitová I, Yeen Z, Wilkin P, de Martin R, Rárová L, Doležal K, Nurcahyo W, Olšanský M.

Sci Rep. 2017 Nov 30;7(1):16653. doi: 10.1038/s41598-017-16621-w.

7.

CD40L and TNF both activate the classical NF-κB pathway, which is not required for the CD40L induced alternative pathway in endothelial cells.

Seigner J, Basilio J, Resch U, de Martin R.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1389-1394. doi: 10.1016/j.bbrc.2017.11.160. Epub 2017 Nov 26.

PMID:
29183724
8.

Anti-thrombotic and pro-fibrinolytic effects of levosimendan in human endothelial cells in vitro.

Krychtiuk KA, Kaun C, Hohensinner PJ, Stojkovic S, Seigner J, Kastl SP, Zuckermann A, Eppel W, Rauscher S, de Martin R, Maurer G, Huber K, Wojta J, Speidl WS.

Vascul Pharmacol. 2017 Mar;90:44-50. doi: 10.1016/j.vph.2017.02.003. Epub 2017 Feb 10.

PMID:
28192257
9.

AHR/CYP1A1 interplay triggers lymphatic barrier breaching in breast cancer spheroids by inducing 12(S)-HETE synthesis.

Nguyen CH, Brenner S, Huttary N, Atanasov AG, Dirsch VM, Chatuphonprasert W, Holzner S, Stadler S, Riha J, Krieger S, de Martin R, Bago-Horvath Z, Krupitza G, Jäger W.

Hum Mol Genet. 2016 Nov 15;25(22):5006-5016. doi: 10.1093/hmg/ddw329.

PMID:
28171546
10.

Three-Dimensional Coculture Model to Analyze the Cross Talk Between Endothelial and Smooth Muscle Cells.

Ganesan MK, Finsterwalder R, Leb H, Resch U, Neumüller K, de Martin R, Petzelbauer P.

Tissue Eng Part C Methods. 2017 Jan;23(1):38-49. doi: 10.1089/ten.TEC.2016.0299.

11.

Interleukin-33 stimulates GM-CSF and M-CSF production by human endothelial cells.

Montanari E, Stojkovic S, Kaun C, Lemberger CE, de Martin R, Rauscher S, Gröger M, Maurer G, Neumayer C, Huk I, Huber K, Demyanets S, Wojta J.

Thromb Haemost. 2016 Aug 1;116(2):317-27. doi: 10.1160/TH15-12-0917. Epub 2016 May 12.

PMID:
27173404
12.

Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation.

Stojkovic S, Kaun C, Basilio J, Rauscher S, Hell L, Krychtiuk KA, Bonstingl C, de Martin R, Gröger M, Ay C, Holnthoner W, Eppel W, Neumayer C, Huk I, Huber K, Demyanets S, Wojta J.

Sci Rep. 2016 May 4;6:25171. doi: 10.1038/srep25171.

13.

NF-κB contributes to MMP1 expression in breast cancer spheroids causing paracrine PAR1 activation and disintegrations in the lymph endothelial barrier in vitro.

Nguyen CH, Senfter D, Basilio J, Holzner S, Stadler S, Krieger S, Huttary N, Milovanovic D, Viola K, Simonitsch-Klupp I, Jäger W, de Martin R, Krupitza G.

Oncotarget. 2015 Nov 17;6(36):39262-75. doi: 10.18632/oncotarget.5741.

14.

The germacranolide sesquiterpene lactone neurolenin B of the medicinal plant Neurolaena lobata (L.) R.Br. ex Cass inhibits NPM/ALK-driven cell expansion and NF-κB-driven tumour intravasation.

Unger C, Kiss I, Vasas A, Lajter I, Kramer N, Atanasov AG, Nguyen CH, Chatuphonprasert W, Brenner S, Krieger S, McKinnon R, Peschel A, Kain R, Saiko P, Szekeres T, Kenner L, Hassler MR, Diaz R, Frisch R, Dirsch VM, Jäger W, de Martin R, Bochkov VN, Passreiter CM, Peter-Vörösmarty B, Mader RM, Grusch M, Dolznig H, Kopp B, Zupko I, Hohmann J, Krupitza G.

Phytomedicine. 2015 Aug 15;22(9):862-74. doi: 10.1016/j.phymed.2015.06.003. Epub 2015 Jun 26.

PMID:
26220634
15.

Alpha-catulin contributes to drug-resistance of melanoma by activating NF-κB and AP-1.

Kreiseder B, Holper-Schichl YM, Muellauer B, Jacobi N, Pretsch A, Schmid JA, de Martin R, Hundsberger H, Eger A, Wiesner C.

PLoS One. 2015 Mar 20;10(3):e0119402. doi: 10.1371/journal.pone.0119402. eCollection 2015.

16.

Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation.

Kiss I, Unger C, Huu CN, Atanasov AG, Kramer N, Chatruphonprasert W, Brenner S, McKinnon R, Peschel A, Vasas A, Lajter I, Kain R, Saiko P, Szekeres T, Kenner L, Hassler MR, Diaz R, Frisch R, Dirsch VM, Jäger W, de Martin R, Bochkov VN, Passreiter CM, Peter-Vörösmarty B, Mader RM, Grusch M, Dolznig H, Kopp B, Zupko I, Hohmann J, Krupitza G.

Cancer Lett. 2015 Jan 28;356(2 Pt B):994-1006. doi: 10.1016/j.canlet.2014.11.019. Epub 2014 Nov 15.

PMID:
25444930
17.

Pharmacological insight into the anti-inflammatory activity of sesquiterpene lactones from Neurolaena lobata (L.) R.Br. ex Cass.

McKinnon R, Binder M, Zupkó I, Afonyushkin T, Lajter I, Vasas A, de Martin R, Unger C, Dolznig H, Diaz R, Frisch R, Passreiter CM, Krupitza G, Hohmann J, Kopp B, Bochkov VN.

Phytomedicine. 2014 Oct 15;21(12):1695-701. doi: 10.1016/j.phymed.2014.07.019. Epub 2014 Sep 15.

PMID:
25442279
18.

Levosimendan exerts anti-inflammatory effects on cardiac myocytes and endothelial cells in vitro.

Krychtiuk KA, Watzke L, Kaun C, Buchberger E, Hofer-Warbinek R, Demyanets S, Pisoni J, Kastl SP, Rauscher S, Gröger M, Aliabadi A, Zuckermann A, Maurer G, de Martin R, Huber K, Wojta J, Speidl WS.

Thromb Haemost. 2015 Feb;113(2):350-62. doi: 10.1160/TH14-06-0549. Epub 2014 Oct 2.

PMID:
25273157
19.

Polyubiquitinated tristetraprolin protects from TNF-induced, caspase-mediated apoptosis.

Resch U, Cuapio A, Sturtzel C, Hofer E, de Martin R, Holper-Schichl YM.

J Biol Chem. 2014 Sep 5;289(36):25088-100. doi: 10.1074/jbc.M114.563312. Epub 2014 Jul 23.

20.

Interleukin-33 induces urokinase in human endothelial cells--possible impact on angiogenesis.

Stojkovic S, Kaun C, Heinz M, Krychtiuk KA, Rauscher S, Lemberger CE, de Martin R, Gröger M, Petzelbauer P, Huk I, Huber K, Wojta J, Demyanets S.

J Thromb Haemost. 2014 Jun;12(6):948-57. doi: 10.1111/jth.12581.

21.

TNFα-induced down-regulation of Sox18 in endothelial cells is dependent on NF-κB.

Basílio J, Hoeth M, Holper-Schichl YM, Resch U, Mayer H, Hofer-Warbinek R, de Martin R.

Biochem Biophys Res Commun. 2013 Dec 13;442(3-4):221-6. doi: 10.1016/j.bbrc.2013.11.030. Epub 2013 Nov 19.

PMID:
24269235
22.

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.

Kopf S, Viola K, Atanasov AG, Jarukamjorn K, Rarova L, Kretschy N, Teichmann M, Vonach C, Saiko P, Giessrigl B, Huttary N, Raab I, Krieger S, Schumacher M, Diederich M, Strnad M, de Martin R, Szekeres T, Jäger W, Dirsch VM, Mikulits W, Grusch M, Dolznig H, Krupitza G.

Arch Toxicol. 2013 Oct;87(10):1851-61. doi: 10.1007/s00204-013-1045-1. Epub 2013 Mar 30.

PMID:
23543012
23.

Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis.

Viola K, Kopf S, Rarova L, Jarukamjorn K, Kretschy N, Teichmann M, Vonach C, Atanasov AG, Giessrigl B, Huttary N, Raab I, Krieger S, Strnad M, de Martin R, Saiko P, Szekeres T, Knasmüller S, Dirsch VM, Jäger W, Grusch M, Dolznig H, Mikulits W, Krupitza G.

Arch Toxicol. 2013 Jul;87(7):1301-12. doi: 10.1007/s00204-013-1028-2. Epub 2013 Mar 17.

PMID:
23503627
24.

Bay11-7082 inhibits the disintegration of the lymphendothelial barrier triggered by MCF-7 breast cancer spheroids; the role of ICAM-1 and adhesion.

Viola K, Kopf S, Huttary N, Vonach C, Kretschy N, Teichmann M, Giessrigl B, Raab I, Stary S, Krieger S, Keller T, Bauer S, Hantusch B, Szekeres T, de Martin R, Jäger W, Mikulits W, Dolznig H, Krupitza G, Grusch M.

Br J Cancer. 2013 Feb 19;108(3):564-9. doi: 10.1038/bjc.2012.485. Epub 2012 Oct 23.

25.

α-Catulin downregulates E-cadherin and promotes melanoma progression and invasion.

Kreiseder B, Orel L, Bujnow C, Buschek S, Pflueger M, Schuett W, Hundsberger H, de Martin R, Wiesner C.

Int J Cancer. 2013 Feb 1;132(3):521-30. doi: 10.1002/ijc.27698. Epub 2012 Jul 14.

26.

An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis.

Unger C, Popescu R, Giessrigl B, Rarova L, Herbacek I, Seelinger M, Diaz R, Wallnöfer B, Fritzer-Szekeres M, Szekeres T, Frisch R, Doležal K, Strnad M, De Martin R, Grusch M, Kopp B, Krupitza G.

Int J Oncol. 2012 Jun;40(6):2131-9. doi: 10.3892/ijo.2012.1412. Epub 2012 Mar 23.

PMID:
22446629
27.

The transcription factor SOX18 regulates the expression of matrix metalloproteinase 7 and guidance molecules in human endothelial cells.

Hoeth M, Niederleithner H, Hofer-Warbinek R, Bilban M, Mayer H, Resch U, Lemberger C, Wagner O, Hofer E, Petzelbauer P, de Martin R.

PLoS One. 2012;7(1):e30982. doi: 10.1371/journal.pone.0030982. Epub 2012 Jan 23.

28.
29.

Interleukin-33 induces expression of adhesion molecules and inflammatory activation in human endothelial cells and in human atherosclerotic plaques.

Demyanets S, Konya V, Kastl SP, Kaun C, Rauscher S, Niessner A, Pentz R, Pfaffenberger S, Rychli K, Lemberger CE, de Martin R, Heinemann A, Huk I, Gröger M, Maurer G, Huber K, Wojta J.

Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2080-9. doi: 10.1161/ATVBAHA.111.231431. Epub 2011 Jul 7.

PMID:
21737781
30.

Delayed recovery of myocardial blood flow after intracoronary stem cell administration.

Gyöngyösi M, Hemetsberger R, Wolbank S, Pichler V, Kaun C, Posa A, Petrasi Z, Petnehazy Ö, Hofer-Warbinek R, de Martin R, Gruber F, Benedek I, Benedek T, Kovacs I, Benedek I Jr, Plass CA, Charwat S, Maurer G.

Stem Cell Rev Rep. 2011 Sep;7(3):616-23. doi: 10.1007/s12015-010-9213-7.

PMID:
21153508
31.

Interaction of the TNFR-receptor associated factor TRAF1 with I-kappa B kinase-2 and TRAF2 indicates a regulatory function for NF-kappa B signaling.

Sughra K, Birbach A, de Martin R, Schmid JA.

PLoS One. 2010 Sep 13;5(9):e12683. doi: 10.1371/journal.pone.0012683.

32.

In vitro anti-inflammatory and anticancer activities of extracts of Acalypha alopecuroidea (Euphorbiaceae).

Madlener S, Svacinová J, Kitner M, Kopecky J, Eytner R, Lackner A, Vo TP, Frisch R, Grusch M, De Martin R, Dolezal K, Strnad M, Krupitza G.

Int J Oncol. 2009 Oct;35(4):881-91.

PMID:
19724926
33.

NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells.

Gruber F, Mayer H, Lengauer B, Mlitz V, Sanders JM, Kadl A, Bilban M, de Martin R, Wagner O, Kensler TW, Yamamoto M, Leitinger N, Tschachler E.

FASEB J. 2010 Jan;24(1):39-48. doi: 10.1096/fj.09-133520. Epub 2009 Aug 31.

34.

Tristetraprolin impairs NF-kappaB/p65 nuclear translocation.

Schichl YM, Resch U, Hofer-Warbinek R, de Martin R.

J Biol Chem. 2009 Oct 23;284(43):29571-81. doi: 10.1074/jbc.M109.031237. Epub 2009 Aug 4.

35.

Thrombin induces the expression of oncostatin M via AP-1 activation in human macrophages: a link between coagulation and inflammation.

Kastl SP, Speidl WS, Katsaros KM, Kaun C, Rega G, Assadian A, Hagmueller GW, Hoeth M, de Martin R, Ma Y, Maurer G, Huber K, Wojta J.

Blood. 2009 Sep 24;114(13):2812-8. doi: 10.1182/blood-2009-01-200915. Epub 2009 Aug 3.

PMID:
19652200
36.

Siva1 is a XIAP-interacting protein that balances NFkappaB and JNK signalling to promote apoptosis.

Resch U, Schichl YM, Winsauer G, Gudi R, Prasad K, de Martin R.

J Cell Sci. 2009 Aug 1;122(Pt 15):2651-61. doi: 10.1242/jcs.049940. Epub 2009 Jul 7.

37.

In vitro anti-cancer activity of two ethno-pharmacological healing plants from Guatemala Pluchea odorata and Phlebodium decumanum.

Gridling M, Stark N, Madlener S, Lackner A, Popescu R, Benedek B, Diaz R, Tut FM, Nha Vo TP, Huber D, Gollinger M, Saiko P, Ozmen A, Mosgoeller W, De Martin R, Eytner R, Wagner KH, Grusch M, Fritzer-Szekeres M, Szekeres T, Kopp B, Frisch R, Krupitza G.

Int J Oncol. 2009 Apr;34(4):1117-28.

PMID:
19287970
38.

XIAP regulates bi-phasic NF-kappaB induction involving physical interaction and ubiquitination of MEKK2.

Winsauer G, Resch U, Hofer-Warbinek R, Schichl YM, de Martin R.

Cell Signal. 2008 Nov;20(11):2107-12. doi: 10.1016/j.cellsig.2008.08.004. Epub 2008 Aug 13.

PMID:
18761086
39.

XIAP regulates intracellular ROS by enhancing antioxidant gene expression.

Resch U, Schichl YM, Sattler S, de Martin R.

Biochem Biophys Res Commun. 2008 Oct 10;375(1):156-61. doi: 10.1016/j.bbrc.2008.07.142. Epub 2008 Aug 8.

PMID:
18692482
40.

In human macrophages the complement component C5a induces the expression of oncostatin M via AP-1 activation.

Kastl SP, Speidl WS, Kaun C, Katsaros KM, Rega G, Afonyushkin T, Bochkov VN, Valent P, Assadian A, Hagmueller GW, Hoeth M, de Martin R, Ma Y, Maurer G, Huber K, Wojta J.

Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):498-503. doi: 10.1161/ATVBAHA.107.160580. Epub 2008 Jan 10.

PMID:
18187666
41.

Alpha-catulin, a Rho signalling component, can regulate NF-kappaB through binding to IKK-beta, and confers resistance to apoptosis.

Wiesner C, Winsauer G, Resch U, Hoeth M, Schmid JA, van Hengel J, van Roy F, Binder BR, de Martin R.

Oncogene. 2008 Apr 3;27(15):2159-69. Epub 2007 Oct 22.

PMID:
17952117
42.

Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor-alpha via an NF-kappaB dependent mechanism.

Hohensinner PJ, Kaun C, Rychli K, Niessner A, Pfaffenberger S, Rega G, de Martin R, Maurer G, Ullrich R, Huber K, Wojta J.

J Thromb Haemost. 2007 Dec;5(12):2520-8. Epub 2007 Oct 8.

43.

A novel 9-amino-acid transactivation domain in the C-terminal part of Sox18.

Sandholzer J, Hoeth M, Piskacek M, Mayer H, de Martin R.

Biochem Biophys Res Commun. 2007 Aug 24;360(2):370-4. Epub 2007 Jun 25.

PMID:
17603017
44.

R-(+)-alpha-lipoic acid inhibits endothelial cell apoptosis and proliferation: involvement of Akt and retinoblastoma protein/E2F-1.

Artwohl M, Muth K, Kosulin K, de Martin R, Hölzenbein T, Rainer G, Freudenthaler A, Huttary N, Schmetterer L, Waldhäusl WK, Baumgartner-Parzer SM.

Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E681-9. Epub 2007 Jun 12.

45.

Resolution of inflammation: intracellular feedback loops in the endothelium.

Winsauer G, de Martin R.

Thromb Haemost. 2007 Mar;97(3):364-9. Review.

PMID:
17334502
47.

Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells.

Tabary O, Boncoeur E, de Martin R, Pepperkok R, Clément A, Schultz C, Jacquot J.

Cell Signal. 2006 May;18(5):652-60. Epub 2005 Aug 9.

PMID:
16084692
48.

TOUCAN 2: the all-inclusive open source workbench for regulatory sequence analysis.

Aerts S, Van Loo P, Thijs G, Mayer H, de Martin R, Moreau Y, De Moor B.

Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W393-6.

49.

IKKbeta-dependent NF-kappaB pathway controls vascular inflammation and intimal hyperplasia.

Bu DX, Erl W, de Martin R, Hansson GK, Yan ZQ.

FASEB J. 2005 Aug;19(10):1293-5. Epub 2005 Jun 6.

PMID:
15939736
50.

A highly conserved proapoptotic gene, IKIP, located next to the APAF1 gene locus, is regulated by p53.

Hofer-Warbinek R, Schmid JA, Mayer H, Winsauer G, Orel L, Mueller B, Wiesner Ch, Binder BR, de Martin R.

Cell Death Differ. 2004 Dec;11(12):1317-25.

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