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Items: 1 to 50 of 278

1.

The role of MurT C-terminal domain in the amidation of Staphylococcus aureus peptidoglycan.

Gonçalves BV, Portela R, Lobo R, Figueiredo TA, Grilo IR, Ludovice AM, de Lencastre H, Dias JS, Sobral RG.

Antimicrob Agents Chemother. 2019 Jul 29. pii: AAC.00957-19. doi: 10.1128/AAC.00957-19. [Epub ahead of print]

PMID:
31358586
2.

Staphylococcus aureus nasal carriage among homeless population in Lisbon, Portugal.

Conceição T, Martins H, Rodrigues S, de Lencastre H, Aires-de-Sousa M.

Eur J Clin Microbiol Infect Dis. 2019 Jul 22. doi: 10.1007/s10096-019-03638-4. [Epub ahead of print]

PMID:
31332610
3.

Genomic Characterization of the Emerging Pathogen Streptococcus pseudopneumoniae.

Garriss G, Nannapaneni P, Simões AS, Browall S, Subramanian K, Sá-Leão R, Goossens H, de Lencastre H, Henriques-Normark B.

MBio. 2019 Jun 25;10(3). pii: e01286-19. doi: 10.1128/mBio.01286-19.

4.

Novel coating containing molybdenum oxide nanoparticles to reduce Staphylococcus aureus contamination on inanimate surfaces.

Piçarra S, Lopes E, Almeida PL, de Lencastre H, Aires-de-Sousa M.

PLoS One. 2019 Mar 18;14(3):e0213151. doi: 10.1371/journal.pone.0213151. eCollection 2019.

5.

Identification of Streptococcus pneumoniae by a real-time PCR assay targeting SP2020.

Tavares DA, Handem S, Carvalho RJ, Paulo AC, de Lencastre H, Hinds J, Sá-Leão R.

Sci Rep. 2019 Mar 1;9(1):3285. doi: 10.1038/s41598-019-39791-1.

6.

Bactericidal activity of octenidine against Staphylococcus aureus harbouring genes encoding multidrug resistance efflux pumps.

Conceição T, de Lencastre H, Aires-de-Sousa M.

J Glob Antimicrob Resist. 2019 Mar;16:239-241. doi: 10.1016/j.jgar.2019.01.033. Epub 2019 Feb 10. No abstract available.

PMID:
30753905
7.

Disease-associated genotypes of the commensal skin bacterium Staphylococcus epidermidis.

Méric G, Mageiros L, Pensar J, Laabei M, Yahara K, Pascoe B, Kittiwan N, Tadee P, Post V, Lamble S, Bowden R, Bray JE, Morgenstern M, Jolley KA, Maiden MCJ, Feil EJ, Didelot X, Miragaia M, de Lencastre H, Moriarty TF, Rohde H, Massey R, Mack D, Corander J, Sheppard SK.

Nat Commun. 2018 Nov 28;9(1):5034. doi: 10.1038/s41467-018-07368-7.

8.

Staphylococcus aureus Infecting and Colonizing Experimental Animals, Macaques, in a Research Animal Facility.

Pardos de la Gandara M, Diaz L, Euler CW, Chung M, Gonzalez A, Cheleuitte C, Freiwald W, Tomasz A, Fischetti VA, de Lencastre H.

Microb Drug Resist. 2019 Jan/Feb;25(1):54-62. doi: 10.1089/mdr.2018.0232. Epub 2018 Nov 27.

PMID:
30481118
9.

European external quality assessments for identification, molecular typing and characterization of Staphylococcus aureus.

Deplano A, Dodémont M, Denis O, Westh H, Gumpert H, Larsen AR, Larsen J, Kearns A, Pichon B, Layer F, Schulte B, Wolz C, Spiliopoulou I, Brennan G, Empel J, Hryniewicz W, de Lencastre H, Faria NA, Codita I, Sabat AJ, Friedrich AW, Deurenberg RH, Tristan A, Laurent F, Vandenesch F.

J Antimicrob Chemother. 2018 Oct 1;73(10):2662-2666. doi: 10.1093/jac/dky260.

PMID:
30099486
10.

Global Scale Dissemination of ST93: A Divergent Staphylococcus aureus Epidemic Lineage That Has Recently Emerged From Remote Northern Australia.

van Hal SJ, Steinig EJ, Andersson P, Holden MTG, Harris SR, Nimmo GR, Williamson DA, Heffernan H, Ritchie SR, Kearns AM, Ellington MJ, Dickson E, de Lencastre H, Coombs GW, Bentley SD, Parkhill J, Holt DC, Giffard PM, Tong SYC.

Front Microbiol. 2018 Jul 9;9:1453. doi: 10.3389/fmicb.2018.01453. eCollection 2018.

11.

Phenotypic signatures and genetic determinants of oxacillin tolerance in a laboratory mutant of Staphylococcus aureus.

Chung M, Borges V, Gomes JP, de Lencastre H, Tomasz A.

PLoS One. 2018 Jul 3;13(7):e0199707. doi: 10.1371/journal.pone.0199707. eCollection 2018.

12.

Correction for Pardos de la Gandara et al., "Genetic Determinants of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus".

Pardos de la Gandara M, Borges V, Chung M, Milheiriço C, Gomes JP, de Lencastre H, Tomasz A.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e01096-18. doi: 10.1128/AAC.01096-18. Print 2018 Jul. No abstract available.

13.

Bactericidal efficacy of molybdenum oxide nanoparticles against antimicrobial-resistant pathogens.

Lopes E, Piçarra S, Almeida PL, de Lencastre H, Aires-de-Sousa M.

J Med Microbiol. 2018 Aug;67(8):1042-1046. doi: 10.1099/jmm.0.000789. Epub 2018 Jun 25.

PMID:
29939129
14.

Methicillin-resistant Staphylococcus aureus.

Lee AS, de Lencastre H, Garau J, Kluytmans J, Malhotra-Kumar S, Peschel A, Harbarth S.

Nat Rev Dis Primers. 2018 May 31;4:18033. doi: 10.1038/nrdp.2018.33. Review.

PMID:
29849094
15.

Frequent MRSA nasal colonization among hospitalized children and their parents in Angola and São Tomé and Príncipe.

Rodrigues S, Conceição T, Silva IS, de Lencastre H, Aires-de-Sousa M.

J Hosp Infect. 2018 Nov;100(3):344-349. doi: 10.1016/j.jhin.2018.05.015. Epub 2018 May 25.

PMID:
29807064
16.

Evaluation of Different Screening Methodologies for the Detection of Methicillin-Resistant Staphylococcus aureus from Environmental Surfaces: Swabs, Gauzes, and Polywipes.

Aires-de-Sousa M, Rodrigues S, Conceição T, de Lencastre H.

Microb Drug Resist. 2018 Jun;24(5):585-589. doi: 10.1089/mdr.2017.0349. Epub 2018 Mar 13.

PMID:
29653476
17.

First insights of peptidoglycan amidation in Gram-positive bacteria - the high-resolution crystal structure of Staphylococcus aureus glutamine amidotransferase GatD.

Leisico F, V Vieira D, Figueiredo TA, Silva M, Cabrita EJ, Sobral RG, Ludovice AM, Trincão J, Romão MJ, de Lencastre H, Santos-Silva T.

Sci Rep. 2018 Mar 28;8(1):5313. doi: 10.1038/s41598-018-22986-3.

18.

Genetic Determinants of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus.

Pardos de la Gandara M, Borges V, Chung M, Milheiriço C, Gomes JP, de Lencastre H, Tomasz A.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00206-18. doi: 10.1128/AAC.00206-18. Print 2018 Jun. Erratum in: Antimicrob Agents Chemother. 2018 Jun 26;62(7):.

19.

Carriage of Staphylococcus aureus among Portuguese nursing students: A longitudinal cohort study over four years of education.

Conceição T, de Lencastre H, Aires-de-Sousa M.

PLoS One. 2017 Nov 30;12(11):e0188855. doi: 10.1371/journal.pone.0188855. eCollection 2017.

20.

Methicillin-resistant Staphylococcus aureus emerged long before the introduction of methicillin into clinical practice.

Harkins CP, Pichon B, Doumith M, Parkhill J, Westh H, Tomasz A, de Lencastre H, Bentley SD, Kearns AM, Holden MTG.

Genome Biol. 2017 Jul 20;18(1):130. doi: 10.1186/s13059-017-1252-9.

21.

Healthy Bovines as Reservoirs of Major Pathogenic Lineages of Staphylococcus aureus in Portugal.

Conceição T, de Lencastre H, Aires-de-Sousa M.

Microb Drug Resist. 2017 Oct;23(7):845-851. doi: 10.1089/mdr.2017.0074. Epub 2017 Jun 26.

PMID:
28650693
22.

Antibiotic Resistance as a Stress Response: Recovery of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus "Auxiliary" (fem) Mutants by Induction of the Stringent Stress Response.

Kim CK, Milheiriço C, de Lencastre H, Tomasz A.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00313-17. doi: 10.1128/AAC.00313-17. Print 2017 Aug.

23.

Frequent isolation of methicillin resistant Staphylococcus aureus (MRSA) ST398 among healthy pigs in Portugal.

Conceição T, de Lencastre H, Aires-de-Sousa M.

PLoS One. 2017 Apr 11;12(4):e0175340. doi: 10.1371/journal.pone.0175340. eCollection 2017.

24.

Evidence for the evolutionary steps leading to mecA-mediated β-lactam resistance in staphylococci.

Rolo J, Worning P, Boye Nielsen J, Sobral R, Bowden R, Bouchami O, Damborg P, Guardabassi L, Perreten V, Westh H, Tomasz A, de Lencastre H, Miragaia M.

PLoS Genet. 2017 Apr 10;13(4):e1006674. doi: 10.1371/journal.pgen.1006674. eCollection 2017 Apr.

25.

Evolutionary Origin of the Staphylococcal Cassette Chromosome mec (SCCmec).

Rolo J, Worning P, Nielsen JB, Bowden R, Bouchami O, Damborg P, Guardabassi L, Perreten V, Tomasz A, Westh H, de Lencastre H, Miragaia M.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02302-16. doi: 10.1128/AAC.02302-16. Print 2017 Jun.

26.

From the Bench to the Barbershop: Community Engagement to Raise Awareness About Community-Acquired Methicillin-Resistant Staphylococcus aureus and Hepatitis C Virus Infection.

Leinberger-Jabari A, Kost RG, D'Orazio B, Burgess R, Khalida C, Tsang A, Mitchell D, Tomasz A, de Lencastre H, Pardos de la Gandara M, Evering TH, Holder T, Coller BS, Tobin JN.

Prog Community Health Partnersh. 2016;10(3):413-423. doi: 10.1353/cpr.2016.0048.

27.

Frequent occurrence of trimethoprim-sulfamethoxazole hetero-resistant Staphylococcus aureus isolates in different African countries.

Coelho C, de Lencastre H, Aires-de-Sousa M.

Eur J Clin Microbiol Infect Dis. 2017 Jul;36(7):1243-1252. doi: 10.1007/s10096-017-2915-x. Epub 2017 Feb 3.

PMID:
28160148
28.

Identification of LukPQ, a novel, equid-adapted leukocidin of Staphylococcus aureus.

Koop G, Vrieling M, Storisteanu DM, Lok LS, Monie T, van Wigcheren G, Raisen C, Ba X, Gleadall N, Hadjirin N, Timmerman AJ, Wagenaar JA, Klunder HM, Fitzgerald JR, Zadoks R, Paterson GK, Torres C, Waller AS, Loeffler A, Loncaric I, Hoet AE, Bergström K, De Martino L, Pomba C, de Lencastre H, Ben Slama K, Gharsa H, Richardson EJ, Chilvers ER, de Haas C, van Kessel K, van Strijp JA, Harrison EM, Holmes MA.

Sci Rep. 2017 Jan 20;7:40660. doi: 10.1038/srep40660.

29.

Full-Genome Sequencing Identifies in the Genetic Background Several Determinants That Modulate the Resistance Phenotype in Methicillin-Resistant Staphylococcus aureus Strains Carrying the Novel mecC Gene.

Milheiriço C, de Lencastre H, Tomasz A.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e02500-16. doi: 10.1128/AAC.02500-16. Print 2017 Mar.

30.

Efficacy of octenidine against antibiotic-resistant Staphylococcus aureus epidemic clones.

Conceição T, de Lencastre H, Aires-de-Sousa M.

J Antimicrob Chemother. 2016 Oct;71(10):2991-4. doi: 10.1093/jac/dkw241. Epub 2016 Jun 21. No abstract available.

PMID:
27334666
31.

Impact of the 13-valent pneumococcal conjugate vaccine on Streptococcus pneumoniae multiple serotype carriage.

Valente C, Hinds J, Gould KA, Pinto FR, de Lencastre H, Sá-Leão R.

Vaccine. 2016 Jul 25;34(34):4072-8. doi: 10.1016/j.vaccine.2016.06.017. Epub 2016 Jun 17.

PMID:
27325351
32.

The blp Locus of Streptococcus pneumoniae Plays a Limited Role in the Selection of Strains That Can Cocolonize the Human Nasopharynx.

Valente C, Dawid S, Pinto FR, Hinds J, Simões AS, Gould KA, Mendes LA, de Lencastre H, Sá-Leão R.

Appl Environ Microbiol. 2016 Aug 15;82(17):5206-15. doi: 10.1128/AEM.01048-16. Print 2016 Sep 1.

33.

Heterogeneous oxacillin-resistant phenotypes and production of PBP2A by oxacillin-susceptible/mecA-positive MRSA strains from Africa.

Chung M, Kim CK, Conceição T, Aires-De-Sousa M, De Lencastre H, Tomasz A.

J Antimicrob Chemother. 2016 Oct;71(10):2804-9. doi: 10.1093/jac/dkw209. Epub 2016 Jun 7.

34.

MRSA Causing Infections in Hospitals in Greater Metropolitan New York: Major Shift in the Dominant Clonal Type between 1996 and 2014.

Pardos de la Gandara M, Curry M, Berger J, Burstein D, Della-Latta P, Kopetz V, Quale J, Spitzer E, Tan R, Urban C, Wang G, Whittier S, de Lencastre H, Tomasz A.

PLoS One. 2016 Jun 7;11(6):e0156924. doi: 10.1371/journal.pone.0156924. eCollection 2016.

35.

Impact of Insertion Sequences and Recombination on the Population Structure of Staphylococcus haemolyticus.

Bouchami O, de Lencastre H, Miragaia M.

PLoS One. 2016 Jun 1;11(6):e0156653. doi: 10.1371/journal.pone.0156653. eCollection 2016.

36.

lytA-based identification methods can misidentify Streptococcus pneumoniae.

Simões AS, Tavares DA, Rolo D, Ardanuy C, Goossens H, Henriques-Normark B, Linares J, de Lencastre H, Sá-Leão R.

Diagn Microbiol Infect Dis. 2016 Jun;85(2):141-8. doi: 10.1016/j.diagmicrobio.2016.03.018. Epub 2016 Mar 29.

PMID:
27107535
37.

Correction: Biofilm Morphotypes and Population Structure among Staphylococcus epidermidis from Commensal and Clinical Samples.

Harris LG, Murray S, Pascoe B, Bray J, Meric G, Mageiros L, Wilkinson TS, Jeeves R, Rohde H, Schwarz S, de Lencastre H, Miragaia M, Rolo J, Bowden R, Jolley KA, Maiden MC, Mack D, Sheppard SK.

PLoS One. 2016 Apr 21;11(4):e0154510. doi: 10.1371/journal.pone.0154510. eCollection 2016. No abstract available.

38.

Biofilm Morphotypes and Population Structure among Staphylococcus epidermidis from Commensal and Clinical Samples.

Harris LG, Murray S, Pascoe B, Bray J, Meric G, Mageiros L, Wilkinson TS, Jeeves R, Rohde H, Schwarz S, de Lencastre H, Miragaia M, Rolo J, Bowden R, Jolley KA, Maiden MC, Mack D, Sheppard SK.

PLoS One. 2016 Mar 15;11(3):e0151240. doi: 10.1371/journal.pone.0151240. eCollection 2016. Erratum in: PLoS One. 2016;11(4):e0154510. Magerios, Leonardos [corrected to Mageiros, Leonardos].

39.

The impact of private use of PCV7 in 2009 and 2010 on serotypes and antimicrobial resistance of Streptococcus pneumoniae carried by young children in Portugal: Comparison with data obtained since 1996 generating a 15-year study prior to PCV13 introduction.

Nunes S, Félix S, Valente C, Simões AS, Tavares DA, Almeida ST, Paulo AC, Brito-Avô A, de Lencastre H, Sá-Leão R.

Vaccine. 2016 Mar 29;34(14):1648-56. doi: 10.1016/j.vaccine.2016.02.045. Epub 2016 Feb 23.

PMID:
26920470
40.

High Prevalence of Biocide Resistance Determinants in Staphylococcus aureus Isolates from Three African Countries.

Conceição T, Coelho C, de Lencastre H, Aires-de-Sousa M.

Antimicrob Agents Chemother. 2015 Nov 9;60(1):678-81. doi: 10.1128/AAC.02140-15. Print 2016 Jan.

41.

Methicillin-Resistant Staphylococcus aureus in the Community in Luanda, Angola: Blurred Boundaries with the Hospital Setting.

Conceição T, Coelho C, Santos Silva I, de Lencastre H, Aires-de-Sousa M.

Microb Drug Resist. 2016 Jan;22(1):22-7. doi: 10.1089/mdr.2015.0236. Epub 2015 Oct 27.

PMID:
26505094
42.

Ability of Antibiotic-Resistant Nonvaccine-Type Pneumococcal Clones to Cause Otitis Media in an Infant Mouse Model of Pneumococcal-Influenza Virus Coinfection.

Frazão N, Hermans P, van Selm S, Sá-Leão R, de Lencastre H, Tomasz A, Diavatopoulos D.

Microb Drug Resist. 2016 Jan;22(1):97-101. doi: 10.1089/mdr.2015.0109. Epub 2015 Sep 14.

PMID:
26366835
43.

Frequent occurrence of oxacillin-susceptible mecA-positive Staphylococcus aureus (OS-MRSA) strains in two African countries.

Conceição T, Coelho C, de Lencastre H, Aires-de-Sousa M.

J Antimicrob Chemother. 2015 Dec;70(12):3200-4. doi: 10.1093/jac/dkv261. Epub 2015 Aug 27.

PMID:
26318189
44.

Molecular Types of Methicillin-Resistant Staphylococcus aureus and Methicillin-Sensitive S. aureus Strains Causing Skin and Soft Tissue Infections and Nasal Colonization, Identified in Community Health Centers in New York City.

Pardos de la Gandara M, Raygoza Garay JA, Mwangi M, Tobin JN, Tsang A, Khalida C, D'Orazio B, Kost RG, Leinberger-Jabari A, Coffran C, Evering TH, Coller BS, Balachandra S, Urban T, Parola C, Salvato S, Jenks N, Wu D, Burgess R, Chung M, de Lencastre H, Tomasz A.

J Clin Microbiol. 2015 Aug;53(8):2648-58. doi: 10.1128/JCM.00591-15. Epub 2015 Jun 10.

45.

Staphylococcus aureus in former Portuguese colonies from Africa and the Far East: missing data to help fill the world map.

Conceição T, Coelho C, Silva IS, de Lencastre H, Aires-de-Sousa M.

Clin Microbiol Infect. 2015 Sep;21(9):842.e1-842.e10. doi: 10.1016/j.cmi.2015.05.010. Epub 2015 May 21.

46.

Ecological Overlap and Horizontal Gene Transfer in Staphylococcus aureus and Staphylococcus epidermidis.

Méric G, Miragaia M, de Been M, Yahara K, Pascoe B, Mageiros L, Mikhail J, Harris LG, Wilkinson TS, Rolo J, Lamble S, Bray JE, Jolley KA, Hanage WP, Bowden R, Maiden MC, Mack D, de Lencastre H, Feil EJ, Corander J, Sheppard SK.

Genome Biol Evol. 2015 Apr 16;7(5):1313-28. doi: 10.1093/gbe/evv066.

47.

Recurrent furunculosis caused by a community-acquired Staphylococcus aureus strain belonging to the USA300 clone.

Balachandra S, Pardos de la Gandara M, Salvato S, Urban T, Parola C, Khalida C, Kost RG, Evering TH, Pastagia M, D'Orazio BM, Tomasz A, de Lencastre H, Tobin JN.

Microb Drug Resist. 2015 Apr;21(2):237-43. doi: 10.1089/mdr.2014.0283. Epub 2015 Feb 10.

48.

Global phylogenomic analysis of nonencapsulated Streptococcus pneumoniae reveals a deep-branching classic lineage that is distinct from multiple sporadic lineages.

Hilty M, Wüthrich D, Salter SJ, Engel H, Campbell S, Sá-Leão R, de Lencastre H, Hermans P, Sadowy E, Turner P, Chewapreecha C, Diggle M, Pluschke G, McGee L, Eser ÖK, Low DE, Smith-Vaughan H, Endimiani A, Küffer M, Dupasquier M, Beaudoing E, Weber J, Bruggmann R, Hanage WP, Parkhill J, Hathaway LJ, Mühlemann K, Bentley SD.

Genome Biol Evol. 2014 Dec 4;6(12):3281-94. doi: 10.1093/gbe/evu263.

49.

Prevalence, risk factors, and epidemiology of methicillin-resistant Staphylococcus aureus carried by adults over 60 years of age.

Almeida ST, Nunes S, Paulo AC, Faria NA, de Lencastre H, Sá-Leão R.

Eur J Clin Microbiol Infect Dis. 2015 Mar;34(3):593-600. doi: 10.1007/s10096-014-2267-8. Epub 2014 Oct 31.

PMID:
25359581
50.

Non-typeable pneumococci circulating in Portugal are of cps type NCC2 and have genomic features typical of encapsulated isolates.

Tavares DA, Simões AS, Bootsma HJ, Hermans PW, de Lencastre H, Sá-Leão R.

BMC Genomics. 2014 Oct 6;15:863. doi: 10.1186/1471-2164-15-863.

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