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Items: 1 to 50 of 393

1.

Specificity of the transport of lipid II by FtsW in Escherichia coli.

Mohammadi T, Sijbrandi R, Lutters M, Verheul J, Martin NI, den Blaauwen T, de Kruijff B, Breukink E.

J Biol Chem. 2014 May 23;289(21):14707-18. doi: 10.1074/jbc.M114.557371. Epub 2014 Apr 7.

2.

Polyene antibiotic that inhibits membrane transport proteins.

te Welscher YM, van Leeuwen MR, de Kruijff B, Dijksterhuis J, Breukink E.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11156-9. doi: 10.1073/pnas.1203375109. Epub 2012 Jun 25.

3.

A novel in vivo cell-wall labeling approach sheds new light on peptidoglycan synthesis in Escherichia coli.

Olrichs NK, Aarsman ME, Verheul J, Arnusch CJ, Martin NI, Hervé M, Vollmer W, de Kruijff B, Breukink E, den Blaauwen T.

Chembiochem. 2011 May 2;12(7):1124-33. doi: 10.1002/cbic.201000552. Epub 2011 Apr 5.

PMID:
21472954
4.

Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane.

Mohammadi T, van Dam V, Sijbrandi R, Vernet T, Zapun A, Bouhss A, Diepeveen-de Bruin M, Nguyen-Distèche M, de Kruijff B, Breukink E.

EMBO J. 2011 Apr 20;30(8):1425-32. doi: 10.1038/emboj.2011.61. Epub 2011 Mar 8.

5.

Self-reproduction of fatty acid vesicles: a combined experimental and simulation study.

Markvoort AJ, Pfleger N, Staffhorst R, Hilbers PA, van Santen RA, Killian JA, de Kruijff B.

Biophys J. 2010 Sep 8;99(5):1520-8. doi: 10.1016/j.bpj.2010.06.057.

6.

Natamycin inhibits vacuole fusion at the priming phase via a specific interaction with ergosterol.

te Welscher YM, Jones L, van Leeuwen MR, Dijksterhuis J, de Kruijff B, Eitzen G, Breukink E.

Antimicrob Agents Chemother. 2010 Jun;54(6):2618-25. doi: 10.1128/AAC.01794-09. Epub 2010 Apr 12.

7.

Impaired processing of human pro-islet amyloid polypeptide is not a causative factor for fibril formation or membrane damage in vitro.

Khemtémourian L, Lahoz Casarramona G, Suylen DP, Hackeng TM, Meeldijk JD, de Kruijff B, Höppener JW, Killian JA.

Biochemistry. 2009 Nov 24;48(46):10918-25. doi: 10.1021/bi901076d.

PMID:
19817482
8.

Cardiolipin molecular species with shorter acyl chains accumulate in Saccharomyces cerevisiae mutants lacking the acyl coenzyme A-binding protein Acb1p: new insights into acyl chain remodeling of cardiolipin.

Rijken PJ, Houtkooper RH, Akbari H, Brouwers JF, Koorengevel MC, de Kruijff B, Frentzen M, Vaz FM, de Kroon AI.

J Biol Chem. 2009 Oct 2;284(40):27609-19. doi: 10.1074/jbc.M109.016311. Epub 2009 Aug 5.

9.

Potential scorpionate antibiotics: targeted hydrolysis of lipid II containing model membranes by vancomycin-TACzyme conjugates and modulation of their antibacterial activity by Zn-ions.

Bauke Albada H, Arnusch CJ, Branderhorst HM, Verel AM, Janssen WT, Breukink E, de Kruijff B, Pieters RJ, Liskamp RM.

Bioorg Med Chem Lett. 2009 Jul 15;19(14):3721-4. doi: 10.1016/j.bmcl.2009.05.064. Epub 2009 May 24.

PMID:
19524434
10.

High cytotoxicity of cisplatin nanocapsules in ovarian carcinoma cells depends on uptake by caveolae-mediated endocytosis.

Hamelers IH, Staffhorst RW, Voortman J, de Kruijff B, Reedijk J, van Bergen en Henegouwen PM, de Kroon AI.

Clin Cancer Res. 2009 Feb 15;15(4):1259-68. doi: 10.1158/1078-0432.CCR-08-1702.

11.

Photocrosslinking and click chemistry enable the specific detection of proteins interacting with phospholipids at the membrane interface.

Gubbens J, Ruijter E, de Fays LE, Damen JM, de Kruijff B, Slijper M, Rijkers DT, Liskamp RM, de Kroon AI.

Chem Biol. 2009 Jan 30;16(1):3-14. doi: 10.1016/j.chembiol.2008.11.009.

12.

Lipid II: a central component in bacterial cell wall synthesis and a target for antibiotics.

de Kruijff B, van Dam V, Breukink E.

Prostaglandins Leukot Essent Fatty Acids. 2008 Sep-Nov;79(3-5):117-21. doi: 10.1016/j.plefa.2008.09.020. Epub 2008 Nov 12. Review.

PMID:
19008088
13.

The vancomycin-nisin(1-12) hybrid restores activity against vancomycin resistant Enterococci.

Arnusch CJ, Bonvin AM, Verel AM, Jansen WT, Liskamp RM, de Kruijff B, Pieters RJ, Breukink E.

Biochemistry. 2008 Dec 2;47(48):12661-3. doi: 10.1021/bi801597b.

PMID:
18989934
14.

Protein complexes in bacterial and yeast mitochondrial membranes differ in their sensitivity towards dissociation by SDS.

Gubbens J, Slijper M, de Kruijff B, de Kroon AI.

Biochim Biophys Acta. 2008 Dec;1784(12):2012-8. doi: 10.1016/j.bbapap.2008.08.020. Epub 2008 Sep 11.

PMID:
18817900
15.

Increased D-alanylation of lipoteichoic acid and a thickened septum are main determinants in the nisin resistance mechanism of Lactococcus lactis.

Kramer NE, Hasper HE, van den Bogaard PT, Morath S, de Kruijff B, Hartung T, Smid EJ, Breukink E, Kok J, Kuipers OP.

Microbiology. 2008 Jun;154(Pt 6):1755-62. doi: 10.1099/mic.0.2007/015412-0.

PMID:
18524930
16.

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane.

Engel MF, Khemtémourian L, Kleijer CC, Meeldijk HJ, Jacobs J, Verkleij AJ, de Kruijff B, Killian JA, Höppener JW.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6033-8. doi: 10.1073/pnas.0708354105. Epub 2008 Apr 11.

17.

Membrane organization and ionization behavior of the minor but crucial lipid ceramide-1-phosphate.

Kooijman EE, Sot J, Montes LR, Alonso A, Gericke A, de Kruijff B, Kumar S, Goñi FM.

Biophys J. 2008 Jun;94(11):4320-30. doi: 10.1529/biophysj.107.121046. Epub 2008 Feb 22.

18.

Protein self-assembly and lipid binding in the folding of the potassium channel KcsA.

Barrera FN, Renart ML, Poveda JA, de Kruijff B, Killian JA, González-Ros JM.

Biochemistry. 2008 Feb 19;47(7):2123-33. doi: 10.1021/bi700778c. Epub 2008 Jan 19.

PMID:
18205389
19.

Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane.

te Welscher YM, ten Napel HH, Balagué MM, Souza CM, Riezman H, de Kruijff B, Breukink E.

J Biol Chem. 2008 Mar 7;283(10):6393-401. doi: 10.1074/jbc.M707821200. Epub 2007 Dec 29.

20.

Phosphatidic acid plays a special role in stabilizing and folding of the tetrameric potassium channel KcsA.

Raja M, Spelbrink RE, de Kruijff B, Killian JA.

FEBS Lett. 2007 Dec 11;581(29):5715-22. Epub 2007 Nov 26.

21.

Enhanced membrane pore formation by multimeric/oligomeric antimicrobial peptides.

Arnusch CJ, Branderhorst H, de Kruijff B, Liskamp RM, Breukink E, Pieters RJ.

Biochemistry. 2007 Nov 20;46(46):13437-42. Epub 2007 Oct 18.

PMID:
17944489
22.
23.

Transmembrane transport of peptidoglycan precursors across model and bacterial membranes.

van Dam V, Sijbrandi R, Kol M, Swiezewska E, de Kruijff B, Breukink E.

Mol Microbiol. 2007 May;64(4):1105-14.

24.

Probing the membrane interface-interacting proteome using photoactivatable lipid cross-linkers.

Gubbens J, Vader P, Damen JM, O'Flaherty MC, Slijper M, de Kruijff B, de Kroon AI.

J Proteome Res. 2007 May;6(5):1951-62. Epub 2007 Mar 22.

PMID:
17375948
25.

An electrostatic/hydrogen bond switch as the basis for the specific interaction of phosphatidic acid with proteins.

Kooijman EE, Tieleman DP, Testerink C, Munnik T, Rijkers DT, Burger KN, de Kruijff B.

J Biol Chem. 2007 Apr 13;282(15):11356-64. Epub 2007 Feb 3.

26.

2,2,2-Trifluoroethanol changes the transition kinetics and subunit interactions in the small bacterial mechanosensitive channel MscS.

Akitake B, Spelbrink RE, Anishkin A, Killian JA, de Kruijff B, Sukharev S.

Biophys J. 2007 Apr 15;92(8):2771-84. Epub 2007 Feb 2.

27.

An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II.

Hasper HE, Kramer NE, Smith JL, Hillman JD, Zachariah C, Kuipers OP, de Kruijff B, Breukink E.

Science. 2006 Sep 15;313(5793):1636-7.

28.

Carboplatin nanocapsules: a highly cytotoxic, phospholipid-based formulation of carboplatin.

Hamelers IH, van Loenen E, Staffhorst RW, de Kruijff B, de Kroon AI.

Mol Cancer Ther. 2006 Aug;5(8):2007-12.

29.

Membrane association of the cycling peroxisome import receptor Pex5p.

Kerssen D, Hambruch E, Klaas W, Platta HW, de Kruijff B, Erdmann R, Kunau WH, Schliebs W.

J Biol Chem. 2006 Sep 15;281(37):27003-15. Epub 2006 Jul 17.

30.

Size and orientation of the lipid II headgroup as revealed by AFM imaging.

Ganchev DN, Hasper HE, Breukink E, de Kruijff B.

Biochemistry. 2006 May 16;45(19):6195-202.

PMID:
16681392
31.

Striated domains: self-organizing ordered assemblies of transmembrane alpha-helical peptides and lipids in bilayers.

de Kruijff B, Killian JA, Ganchev DN, Rinia HA, Sparr E.

Biol Chem. 2006 Mar;387(3):235-41. Review.

PMID:
16542143
32.

Lipid II as a target for antibiotics.

Breukink E, de Kruijff B.

Nat Rev Drug Discov. 2006 Apr;5(4):321-32. Review.

PMID:
16531990
33.

Islet amyloid polypeptide inserts into phospholipid monolayers as monomer.

Engel MF, Yigittop H, Elgersma RC, Rijkers DT, Liskamp RM, de Kruijff B, Höppener JW, Antoinette Killian J.

J Mol Biol. 2006 Feb 24;356(3):783-9. Epub 2005 Dec 21.

PMID:
16403520
34.

What makes the bioactive lipids phosphatidic acid and lysophosphatidic acid so special?

Kooijman EE, Carter KM, van Laar EG, Chupin V, Burger KN, de Kruijff B.

Biochemistry. 2005 Dec 27;44(51):17007-15.

PMID:
16363814
35.

Depletion of phosphatidylcholine in yeast induces shortening and increased saturation of the lipid acyl chains: evidence for regulation of intrinsic membrane curvature in a eukaryote.

Boumann HA, Gubbens J, Koorengevel MC, Oh CS, Martin CE, Heck AJ, Patton-Vogt J, Henry SA, de Kruijff B, de Kroon AI.

Mol Biol Cell. 2006 Feb;17(2):1006-17. Epub 2005 Dec 7.

36.

Covalently dimerized SecA is functional in protein translocation.

de Keyzer J, van der Sluis EO, Spelbrink RE, Nijstad N, de Kruijff B, Nouwen N, van der Does C, Driessen AJ.

J Biol Chem. 2005 Oct 21;280(42):35255-60. Epub 2005 Aug 22.

37.

Detection and identification of stable oligomeric protein complexes in Escherichi coli inner membranes: a proteomics approach.

Spelbrink RE, Kolkman A, Slijper M, Killian JA, de Kruijff B.

J Biol Chem. 2005 Aug 5;280(31):28742-8. Epub 2005 May 25.

38.

A synergistic effect between cholesterol and tryptophan-flanked transmembrane helices modulates membrane curvature.

van Duyl BY, Meeldijk H, Verkleij AJ, Rijkers DT, Chupin V, de Kruijff B, Killian JA.

Biochemistry. 2005 Mar 22;44(11):4526-32.

PMID:
15766283
39.

Spontaneous curvature of phosphatidic acid and lysophosphatidic acid.

Kooijman EE, Chupin V, Fuller NL, Kozlov MM, de Kruijff B, Burger KN, Rand PR.

Biochemistry. 2005 Feb 15;44(6):2097-102.

PMID:
15697235
40.

Molecular organization in striated domains induced by transmembrane alpha-helical peptides in dipalmitoyl phosphatidylcholine bilayers.

Sparr E, Ganchev DN, Snel MM, Ridder AN, Kroon-Batenburg LM, Chupin V, Rijkers DT, Killian JA, de Kruijff B.

Biochemistry. 2005 Jan 11;44(1):2-10.

PMID:
15628840
41.

Targeting extracellular pyrophosphates underpins the high selectivity of nisin.

Bonev BB, Breukink E, Swiezewska E, De Kruijff B, Watts A.

FASEB J. 2004 Dec;18(15):1862-9.

PMID:
15576489
42.

Strength of integration of transmembrane alpha-helical peptides in lipid bilayers as determined by atomic force spectroscopy.

Ganchev DN, Rijkers DT, Snel MM, Killian JA, de Kruijff B.

Biochemistry. 2004 Nov 30;43(47):14987-93.

PMID:
15554706
43.

The role of lipids in membrane insertion and translocation of bacterial proteins.

van Dalen A, de Kruijff B.

Biochim Biophys Acta. 2004 Nov 11;1694(1-3):97-109. Review.

44.

Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers.

Sparr E, Engel MF, Sakharov DV, Sprong M, Jacobs J, de Kruijff B, Höppener JW, Killian JA.

FEBS Lett. 2004 Nov 5;577(1-2):117-20.

45.

Nonbilayer lipids affect peripheral and integral membrane proteins via changes in the lateral pressure profile.

van den Brink-van der Laan E, Killian JA, de Kruijff B.

Biochim Biophys Acta. 2004 Nov 3;1666(1-2):275-88. Review.

46.

Molecular architecture of nanocapsules, bilayer-enclosed solid particles of Cisplatin.

Chupin V, de Kroon AI, de Kruijff B.

J Am Chem Soc. 2004 Oct 27;126(42):13816-21.

PMID:
15493941
47.

Resistance of Gram-positive bacteria to nisin is not determined by lipid II levels.

Kramer NE, Smid EJ, Kok J, de Kruijff B, Kuipers OP, Breukink E.

FEMS Microbiol Lett. 2004 Oct 1;239(1):157-61.

48.

The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics.

Hsu ST, Breukink E, Tischenko E, Lutters MA, de Kruijff B, Kaptein R, Bonvin AM, van Nuland NA.

Nat Struct Mol Biol. 2004 Oct;11(10):963-7. Epub 2004 Sep 12.

PMID:
15361862
49.

Assembly and stability of nisin-lipid II pores.

Hasper HE, de Kruijff B, Breukink E.

Biochemistry. 2004 Sep 14;43(36):11567-75.

PMID:
15350143
50.

The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro.

Boumann HA, Chin PT, Heck AJ, De Kruijff B, De Kroon AI.

J Biol Chem. 2004 Sep 24;279(39):40314-9. Epub 2004 Jul 16.

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