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Items: 1 to 50 of 142

1.

A transcriptomic roadmap to alpha- and beta cell differentiation in the embryonic pancreas.

van Gurp L, Muraro MJ, Dielen T, Seneby L, Dharmadhikari G, Gradwohl G, van Oudenaarden A, de Koning EJP.

Development. 2019 Jun 3. pii: dev.173716. doi: 10.1242/dev.173716. [Epub ahead of print]

PMID:
31160419
2.

Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults.

van Ballegooijen AJ, Beulens JWJ, Schurgers LJ, de Koning EJ, Lips P, van Schoor NM, Vervloet MG.

Nutrients. 2019 Jan 22;11(2). pii: E231. doi: 10.3390/nu11020231.

3.

In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion.

Bijkerk R, Esguerra JLS, Ellenbroek JH, Au YW, Hanegraaf MAJ, de Koning EJ, Eliasson L, van Zonneveld AJ.

Nucleic Acid Ther. 2019 Apr;29(2):67-72. doi: 10.1089/nat.2018.0763. Epub 2019 Jan 23.

PMID:
30672723
4.

Patient activation in individuals with type 2 diabetes mellitus: associated factors and the role of insulin.

van Vugt HA, Boels AM, de Weerdt I, de Koning EJ, Rutten GE.

Patient Prefer Adherence. 2018 Dec 28;13:73-81. doi: 10.2147/PPA.S188391. eCollection 2019.

5.

Within-person pain variability and physical activity in older adults with osteoarthritis from six European countries.

Timmermans EJ, de Koning EJ, van Schoor NM, van der Pas S, Denkinger MD, Dennison EM, Maggi S, Pedersen NL, Otero Á, Peter R, Cooper C, Siviero P, Castell MV, Herbolsheimer F, Edwards M, Limongi F, Deeg DJH, Schaap LA.

BMC Musculoskelet Disord. 2019 Jan 5;20(1):12. doi: 10.1186/s12891-018-2392-0.

6.

Bioluminescent reporter assay for monitoring ER stress in human beta cells.

Kracht MJL, de Koning EJP, Hoeben RC, Roep BO, Zaldumbide A.

Sci Rep. 2018 Dec 10;8(1):17738. doi: 10.1038/s41598-018-36142-4.

7.

Associated auto-immune disease in type 1 diabetes patients: a systematic review and meta-analysis.

Nederstigt C, Uitbeijerse BS, Janssen LGM, Corssmit EPM, de Koning EJP, Dekkers OM.

Eur J Endocrinol. 2019 Feb 1;180(2):135-144. doi: 10.1530/EJE-18-0515.

PMID:
30508413
8.

Hypothermic Oxygenated Machine Perfusion of the Human Donor Pancreas.

Leemkuil M, Lier G, Engelse MA, Ploeg RJ, de Koning EJP, 't Hart NA, Krikke C, Leuvenink HGD.

Transplant Direct. 2018 Sep 7;4(10):e388. doi: 10.1097/TXD.0000000000000829. eCollection 2018 Oct.

9.

Change in serum 25-hydroxyvitamin D and parallel change in depressive symptoms in Dutch older adults

Elstgeest LEM, de Koning EJ, Brouwer IA, van Schoor NM, Penninx BWJH, Visser M.

Eur J Endocrinol. 2018 Oct 1;179(4):239-249. doi: 10.1530/EJE-18-0187.

PMID:
30299894
10.

Artificial Pancreas or Novel Beta-Cell Replacement Therapies: a Race for Optimal Glycemic Control?

Nijhoff MF, de Koning EJP.

Curr Diab Rep. 2018 Sep 24;18(11):110. doi: 10.1007/s11892-018-1073-6. Review.

11.

RVCL-S and CADASIL display distinct impaired vascular function.

de Boer I, Stam AH, Buntinx L, Zielman R, van der Steen I, van den Maagdenberg AMJM, de Koning EJP, Ferrari MD, de Hoon JN, Terwindt GM.

Neurology. 2018 Sep 4;91(10):e956-e963. doi: 10.1212/WNL.0000000000006119. Epub 2018 Aug 3.

PMID:
30076273
12.

Change in serum 25-hydroxyvitamin D and parallel change in depressive symptoms in Dutch older adults.

Elstgeest LEM, de Koning EJ, Brouwer IA, van Schoor NM, Penninx BWJH, Visser M.

Eur J Endocrinol. 2018 Jul 27. pii: EJE-18-0187. doi: 10.1530/EJE-18-0187. [Epub ahead of print]

PMID:
30054306
13.

Vitamin D Status and Depressive Symptoms in Older Adults: A Role for Physical Functioning?

de Koning EJ, Elstgeest LEM, Comijs HC, Lips P, Rijnhart JJM, van Marwijk HWJ, Beekman ATF, Visser M, Penninx BWJH, van Schoor NM.

Am J Geriatr Psychiatry. 2018 Nov;26(11):1131-1143. doi: 10.1016/j.jagp.2018.03.004. Epub 2018 Mar 12.

PMID:
29628322
14.

Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential.

Loomans CJM, Williams Giuliani N, Balak J, Ringnalda F, van Gurp L, Huch M, Boj SF, Sato T, Kester L, de Sousa Lopes SMC, Roost MS, Bonner-Weir S, Engelse MA, Rabelink TJ, Heimberg H, Vries RGJ, van Oudenaarden A, Carlotti F, Clevers H, de Koning EJP.

Stem Cell Reports. 2018 Mar 13;10(3):712-724. doi: 10.1016/j.stemcr.2018.02.005.

15.

Defining Outcomes for β-cell Replacement Therapy in the Treatment of Diabetes: A Consensus Report on the Igls Criteria From the IPITA/EPITA Opinion Leaders Workshop.

Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S.

Transplantation. 2018 Sep;102(9):1479-1486. doi: 10.1097/TP.0000000000002158. Review.

16.

Defining outcomes for beta cell replacement therapy: a work in progress.

Piemonti L, de Koning EJP, Berney T, Odorico JS, Markmann JF, Stock PG, Rickels MR.

Diabetologia. 2018 Jun;61(6):1273-1276. doi: 10.1007/s00125-018-4588-0. Epub 2018 Mar 6.

17.

Within-Person Pain Variability and Mental Health in Older Adults With Osteoarthritis: An Analysis Across 6 European Cohorts.

de Koning EJ, Timmermans EJ, van Schoor NM, Stubbs B, van den Kommer TN, Dennison EM, Limongi F, Castell MV, Edwards MH, Queipo R, Cooper C, Siviero P, van der Pas S, Pedersen NL, Sánchez-Martínez M, Deeg DJH, Denkinger MD; EPOSA Group.

J Pain. 2018 Jun;19(6):690-698. doi: 10.1016/j.jpain.2018.02.006. Epub 2018 Mar 2.

18.

[Transplantation of islets of Langerhans: procedure, indications and challenges].

Nijhoff MF, Huurman VAL, Dubbeld J, van Erkel AR, Rabelink TA, Engelse MA, de Koning EJP.

Ned Tijdschr Geneeskd. 2018;162:D2201. Dutch.

PMID:
29493470
19.

Defining outcomes for β-cell replacement therapy in the treatment of diabetes: a consensus report on the Igls criteria from the IPITA/EPITA opinion leaders workshop.

Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S.

Transpl Int. 2018 Apr;31(4):343-352. doi: 10.1111/tri.13138. Review.

20.

Islet cells share promoter hypomethylation independently of expression, but exhibit cell-type-specific methylation in enhancers.

Neiman D, Moss J, Hecht M, Magenheim J, Piyanzin S, Shapiro AMJ, de Koning EJP, Razin A, Cedar H, Shemer R, Dor Y.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13525-13530. doi: 10.1073/pnas.1713736114. Epub 2017 Dec 4.

21.

Interrelationship of the rs7903146 TCF7L2 gene variant with measures of glucose metabolism and adiposity: The NEO study.

Noordam R, Zwetsloot CPA, de Mutsert R, Mook-Kanamori DO, Lamb HJ, de Roos A, de Koning EJP, Rosendaal FR, Willems van Dijk K, van Heemst D.

Nutr Metab Cardiovasc Dis. 2018 Feb;28(2):150-157. doi: 10.1016/j.numecd.2017.10.012. Epub 2017 Oct 18.

PMID:
29174029
22.

Islet alloautotransplantation: Allogeneic pancreas transplantation followed by transplant pancreatectomy and islet transplantation.

Nijhoff MF, Dubbeld J, van Erkel AR, van der Boog PJM, Rabelink TJ, Engelse MA, de Koning EJP.

Am J Transplant. 2018 Apr;18(4):1016-1019. doi: 10.1111/ajt.14593. Epub 2017 Dec 18.

23.

DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells.

Roost MS, Slieker RC, Bialecka M, van Iperen L, Gomes Fernandes MM, He N, Suchiman HED, Szuhai K, Carlotti F, de Koning EJP, Mummery CL, Heijmans BT, Chuva de Sousa Lopes SM.

Nat Commun. 2017 Oct 13;8(1):908. doi: 10.1038/s41467-017-01077-3.

24.

Pancreas Transplantation With Grafts From Donors Deceased After Circulatory Death: 5 Years Single-Center Experience.

Kopp WH, Lam HD, Schaapherder AFM, Huurman VAL, van der Boog PJM, de Koning EJP, de Fijter JW, Baranski AG, Braat AE.

Transplantation. 2018 Feb;102(2):333-339. doi: 10.1097/TP.0000000000001940.

PMID:
28885491
25.

Pancreatic islet macroencapsulation using microwell porous membranes.

Skrzypek K, Groot Nibbelink M, van Lente J, Buitinga M, Engelse MA, de Koning EJP, Karperien M, van Apeldoorn A, Stamatialis D.

Sci Rep. 2017 Aug 23;7(1):9186. doi: 10.1038/s41598-017-09647-7.

26.

The relationship between serum 25(OH)D levels and anxiety symptoms in older persons: Results from the Longitudinal Aging Study Amsterdam.

de Koning EJ, Verweij L, Lips P, Beekman ATF, Comijs HC, van Schoor NM.

J Psychosom Res. 2017 Jun;97:90-95. doi: 10.1016/j.jpsychores.2017.04.005. Epub 2017 Apr 20.

PMID:
28606505
27.

Pancreatic α-cell mass in obesity.

Ellenbroek JH, Töns HAM, Hanegraaf MAJ, Rabelink TJ, Engelse MA, Carlotti F, de Koning EJP.

Diabetes Obes Metab. 2017 Dec;19(12):1810-1813. doi: 10.1111/dom.12997. Epub 2017 Jul 13.

PMID:
28474364
28.

Increased vimentin in human α- and β-cells in type 2 diabetes.

Roefs MM, Carlotti F, Jones K, Wills H, Hamilton A, Verschoor M, Durkin JMW, Garcia-Perez L, Brereton MF, McCulloch L, Engelse MA, Johnson PRV, Hansen BC, Docherty K, de Koning EJP, Clark A.

J Endocrinol. 2017 Jun;233(3):217-227. doi: 10.1530/JOE-16-0588. Epub 2017 Mar 27.

PMID:
28348116
29.

Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes.

Kracht MJ, van Lummel M, Nikolic T, Joosten AM, Laban S, van der Slik AR, van Veelen PA, Carlotti F, de Koning EJ, Hoeben RC, Zaldumbide A, Roep BO.

Nat Med. 2017 Apr;23(4):501-507. doi: 10.1038/nm.4289. Epub 2017 Feb 27.

PMID:
28263308
30.

Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT.

de Koning EJ, van der Zwaluw NL, van Wijngaarden JP, Sohl E, Brouwer-Brolsma EM, van Marwijk HW, Enneman AW, Swart KM, van Dijk SC, Ham AC, van der Velde N, Uitterlinden AG, Penninx BW, Elders PJ, Lips P, Dhonukshe-Rutten RA, van Schoor NM, de Groot LC.

Nutrients. 2016 Nov 23;8(11). pii: E748.

31.

Fatty acid intake and its dietary sources in relation with markers of type 2 diabetes risk: The NEO study.

Wanders AJ, Alssema M, de Koning EJ, le Cessie S, de Vries JH, Zock PL, Rosendaal FR, Heijer MD, de Mutsert R.

Eur J Clin Nutr. 2017 Feb;71(2):245-251. doi: 10.1038/ejcn.2016.204. Epub 2016 Nov 9.

PMID:
27827396
32.

A Single-Cell Transcriptome Atlas of the Human Pancreas.

Muraro MJ, Dharmadhikari G, Grün D, Groen N, Dielen T, Jansen E, van Gurp L, Engelse MA, Carlotti F, de Koning EJ, van Oudenaarden A.

Cell Syst. 2016 Oct 26;3(4):385-394.e3. doi: 10.1016/j.cels.2016.09.002. Epub 2016 Sep 29.

33.

Sequential intravital imaging reveals in vivo dynamics of pancreatic tissue transplanted under the kidney capsule in mice.

van Gurp L, Loomans CJM, van Krieken PP, Dharmadhikari G, Jansen E, Ringnalda FCAS, Beerling E, van Rheenen J, de Koning EJP.

Diabetologia. 2016 Nov;59(11):2387-2392. doi: 10.1007/s00125-016-4049-6. Epub 2016 Jul 21.

34.

[From annual check-up to annual appraisal: personalised diabetes care].

Rutten GE, van Vugt HA, de Weerdt I, Lamberts SW, de Koning EJ.

Ned Tijdschr Geneeskd. 2016;160:D342. Dutch.

PMID:
27405571
35.

De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data.

Grün D, Muraro MJ, Boisset JC, Wiebrands K, Lyubimova A, Dharmadhikari G, van den Born M, van Es J, Jansen E, Clevers H, de Koning EJP, van Oudenaarden A.

Cell Stem Cell. 2016 Aug 4;19(2):266-277. doi: 10.1016/j.stem.2016.05.010. Epub 2016 Jun 23.

36.

Distinct activation of primary human BDCA1(+) dendritic cells upon interaction with stressed or infected β cells.

Schulte BM, Kers-Rebel ED, Bottino R, Piganelli JD, Galama JM, Engelse MA, de Koning EJ, Adema GJ.

Clin Exp Immunol. 2016 Jun;184(3):293-307. doi: 10.1111/cei.12779. Epub 2016 Mar 23.

37.

Incidence and prevalence of thyroid dysfunction in type 1 diabetes.

Nederstigt C, Corssmit EP, de Koning EJ, Dekkers OM.

J Diabetes Complications. 2016 Apr;30(3):420-5. doi: 10.1016/j.jdiacomp.2015.12.027. Epub 2016 Jan 6.

PMID:
26868720
38.

Human islets and dendritic cells generate post-translationally modified islet autoantigens.

McLaughlin RJ, de Haan A, Zaldumbide A, de Koning EJ, de Ru AH, van Veelen PA, van Lummel M, Roep BO.

Clin Exp Immunol. 2016 Aug;185(2):133-40. doi: 10.1111/cei.12775. Epub 2016 May 17.

39.

Simultaneous pancreas-kidney transplantation in patients with type 1 diabetes reverses elevated MBL levels in association with MBL2 genotype and VEGF expression.

Bijkerk R, van der Pol P, Khairoun M, van Gijlswijk-Jansen DJ, Lievers E, de Vries AP, de Koning EJ, de Fijter HW, Roelen DL, Vossen RH, van Zonneveld AJ, van Kooten C, Reinders ME.

Diabetologia. 2016 Apr;59(4):853-8. doi: 10.1007/s00125-015-3858-3. Epub 2016 Jan 15.

40.

Vitamin D, PTH and the risk of overall and disease-specific mortality: Results of the Longitudinal Aging Study Amsterdam.

El Hilali J, de Koning EJ, van Ballegooijen AJ, Lips P, Sohl E, van Marwijk HWJ, Visser M, van Schoor NM.

J Steroid Biochem Mol Biol. 2016 Nov;164:386-394. doi: 10.1016/j.jsbmb.2015.12.001. Epub 2015 Dec 8.

PMID:
26678328
41.

Vitamin D supplementation to prevent depression and poor physical function in older adults: Study protocol of the D-Vitaal study, a randomized placebo-controlled clinical trial.

de Koning EJ, van Schoor NM, Penninx BW, Elders PJ, Heijboer AC, Smit JH, Bet PM, van Tulder MW, den Heijer M, van Marwijk HW, Lips P.

BMC Geriatr. 2015 Nov 19;15:151. doi: 10.1186/s12877-015-0148-3.

42.

DNA Methylation Landscapes of Human Fetal Development.

Slieker RC, Roost MS, van Iperen L, Suchiman HE, Tobi EW, Carlotti F, de Koning EJ, Slagboom PE, Heijmans BT, Chuva de Sousa Lopes SM.

PLoS Genet. 2015 Oct 22;11(10):e1005583. doi: 10.1371/journal.pgen.1005583. eCollection 2015 Oct.

43.

DAMP production by human islets under low oxygen and nutrients in the presence or absence of an immunoisolating-capsule and necrostatin-1.

Paredes-Juarez GA, Sahasrabudhe NM, Tjoelker RS, de Haan BJ, Engelse MA, de Koning EJP, Faas MM, de Vos P.

Sci Rep. 2015 Sep 30;5:14623. doi: 10.1038/srep14623.

44.

[Maturity-onset diabetes of the young].

van der Tuin K, Hannema SE, Houdijk EC, Losekoot M, de Koning EJ, Breuning MH.

Ned Tijdschr Geneeskd. 2015;159:A9247. Review. Dutch.

PMID:
26374728
45.

Glycemic Stability Through Islet-After-Kidney Transplantation Using an Alemtuzumab-Based Induction Regimen and Long-Term Triple-Maintenance Immunosuppression.

Nijhoff MF, Engelse MA, Dubbeld J, Braat AE, Ringers J, Roelen DL, van Erkel AR, Spijker HS, Bouwsma H, van der Boog PJ, de Fijter JW, Rabelink TJ, de Koning EJ.

Am J Transplant. 2016 Jan;16(1):246-53. doi: 10.1111/ajt.13425. Epub 2015 Aug 19.

46.

Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.

Hoelen H, Zaldumbide A, van Leeuwen WF, Torfs EC, Engelse MA, Hassan C, Lebbink RJ, de Koning EJ, Resssing ME, de Ru AH, van Veelen PA, Hoeben RC, Roep BO, Wiertz EJ.

PLoS One. 2015 Jun 24;10(6):e0128206. doi: 10.1371/journal.pone.0128206. eCollection 2015.

47.

KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas.

Roost MS, van Iperen L, Ariyurek Y, Buermans HP, Arindrarto W, Devalla HD, Passier R, Mummery CL, Carlotti F, de Koning EJ, van Zwet EW, Goeman JJ, Chuva de Sousa Lopes SM.

Stem Cell Reports. 2015 Jun 9;4(6):1112-24. doi: 10.1016/j.stemcr.2015.05.002. Epub 2015 May 28.

48.

Loss of β-Cell Identity Occurs in Type 2 Diabetes and Is Associated With Islet Amyloid Deposits.

Spijker HS, Song H, Ellenbroek JH, Roefs MM, Engelse MA, Bos E, Koster AJ, Rabelink TJ, Hansen BC, Clark A, Carlotti F, de Koning EJ.

Diabetes. 2015 Aug;64(8):2928-38. doi: 10.2337/db14-1752. Epub 2015 Apr 27.

49.

Circulating microRNAs associate with diabetic nephropathy and systemic microvascular damage and normalize after simultaneous pancreas-kidney transplantation.

Bijkerk R, Duijs JM, Khairoun M, Ter Horst CJ, van der Pol P, Mallat MJ, Rotmans JI, de Vries AP, de Koning EJ, de Fijter JW, Rabelink TJ, van Zonneveld AJ, Reinders ME.

Am J Transplant. 2015 Apr;15(4):1081-90. doi: 10.1111/ajt.13072. Epub 2015 Feb 25.

50.

Thirty Years of Pancreas Transplantation at Leiden University Medical Center: Long-term Follow-up in a Large Eurotransplant Center.

Kopp WH, Verhagen MJ, Blok JJ, Huurman VA, de Fijter JW, de Koning EJ, Putter H, Baranski AG, Schaapherder AF, Braat AE, Ringers J.

Transplantation. 2015 Sep;99(9):e145-51. doi: 10.1097/TP.0000000000000604.

PMID:
25706281

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