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Items: 1 to 50 of 334

1.

Distinguishing Between Monomeric scFv and Diabody in Solution Using Light and Small Angle X-ray Scattering.

Lüdel F, Bufe S, Bleymüller WM, de Jonge H, Iamele L, Niemann HH, Hellweg T.

Antibodies (Basel). 2019 Sep 23;8(4). pii: E48. doi: 10.3390/antib8040048.

2.

Impaired Intestinal Farnesoid X Receptor Signaling in Cystic Fibrosis Mice.

Ikpa PT, Doktorova M, Meijsen KF, Nieuwenhuijze NDA, Verkade HJ, Jonker JW, de Jonge HR, Bijvelds MJC.

Cell Mol Gastroenterol Hepatol. 2019 Aug 27. pii: S2352-345X(19)30112-2. doi: 10.1016/j.jcmgh.2019.08.006. [Epub ahead of print]

3.

NHERF3 is necessary for Escherichia coli heat-stable enterotoxin-induced inhibition of NHE3: differences in signaling in mouse small intestine and Caco-2 cells.

Chen T, Lin R, Avula L, Sarker R, Yang J, Cha B, Tse CM, McNamara G, Seidler U, Waldman S, Snook A, Bijvelds MJC, de Jonge HR, Li X, Donowitz M.

Am J Physiol Cell Physiol. 2019 Oct 1;317(4):C737-C748. doi: 10.1152/ajpcell.00351.2018. Epub 2019 Jul 31.

PMID:
31365292
4.

Assessing cell-specific effects of genetic variations using tRNA microarrays.

Polte C, Wedemeyer D, Oliver KE, Wagner J, Bijvelds MJC, Mahoney J, de Jonge HR, Sorscher EJ, Ignatova Z.

BMC Genomics. 2019 Jul 16;20(Suppl 8):549. doi: 10.1186/s12864-019-5864-1.

5.

Transcriptome analysis of the distal small intestine of Cftr null mice.

Ikpa PT, Meijsen KF, Nieuwenhuijze NDA, Dulla K, de Jonge HR, Bijvelds MJC.

Genomics. 2019 Jun 25. pii: S0888-7543(19)30298-8. doi: 10.1016/j.ygeno.2019.06.028. [Epub ahead of print]

6.

Evaluation of eluforsen, a novel RNA oligonucleotide for restoration of CFTR function in in vitro and murine models of p.Phe508del cystic fibrosis.

Beumer W, Swildens J, Leal T, Noel S, Anthonijsz H, van der Horst G, Kuiperij-Boersma H, Potman M, van Putten C, Biasutto P, Platenburg G, de Jonge H, Henig N, Ritsema T.

PLoS One. 2019 Jun 28;14(6):e0219182. doi: 10.1371/journal.pone.0219182. eCollection 2019.

7.

Mini-gut: a promising model for drug development.

Yin YB, de Jonge HR, Wu X, Yin YL.

Drug Discov Today. 2019 Sep;24(9):1784-1794. doi: 10.1016/j.drudis.2019.06.006. Epub 2019 Jun 15. Review.

PMID:
31212027
8.

Inflammatory bowel disease in Shwachman-Diamond syndrome; is there an association?

Nissen LHC, Stuurman KE, van der Feen C, Kemperman FA, Pruijt JFM, de Jonge HJM.

Clin Res Hepatol Gastroenterol. 2019 Jun 10. pii: S2210-7401(19)30103-2. doi: 10.1016/j.clinre.2019.05.006. [Epub ahead of print]

PMID:
31196706
9.

The other cat scratch disease.

Kortmann YFC, de Jonge HJM.

Neth J Med. 2019 Apr;77(3):122. No abstract available.

10.

Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR.

Bose SJ, Bijvelds MJC, Wang Y, Liu J, Cai Z, Bot AGM, de Jonge HR, Sheppard DN.

Am J Physiol Lung Cell Mol Physiol. 2019 Jul 1;317(1):L71-L86. doi: 10.1152/ajplung.00034.2019. Epub 2019 Apr 10.

11.

Enteroids for Nutritional Studies.

Yin YB, de Jonge HR, Wu X, Yin YL.

Mol Nutr Food Res. 2019 Aug;63(16):e1801143. doi: 10.1002/mnfr.201801143. Epub 2019 Apr 10. Review.

PMID:
30883003
12.

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis.

Berkers G, van Mourik P, Vonk AM, Kruisselbrink E, Dekkers JF, de Winter-de Groot KM, Arets HGM, Marck-van der Wilt REP, Dijkema JS, Vanderschuren MM, Houwen RHJ, Heijerman HGM, van de Graaf EA, Elias SG, Majoor CJ, Koppelman GH, Roukema J, Bakker M, Janssens HM, van der Meer R, Vries RGJ, Clevers HC, de Jonge HR, Beekman JM, van der Ent CK.

Cell Rep. 2019 Feb 12;26(7):1701-1708.e3. doi: 10.1016/j.celrep.2019.01.068.

13.

Folding-function relationship of the most common cystic fibrosis-causing CFTR conductance mutants.

van Willigen M, Vonk AM, Yeoh HY, Kruisselbrink E, Kleizen B, van der Ent CK, Egmond MR, de Jonge HR, Braakman I, Beekman JM, van der Sluijs P.

Life Sci Alliance. 2019 Jan 18;2(1). pii: e201800172. doi: 10.26508/lsa.201800172. Print 2019 Feb.

14.

Defective FXR-FGF15 signaling and bile acid homeostasis in cystic fibrosis mice can be restored by the laxative polyethylene glycol.

Bertolini A, van de Peppel IP, Doktorova-Demmin M, Bodewes FAJA, de Jonge H, Bijvelds M, Verkade HJ, Jonker JW.

Am J Physiol Gastrointest Liver Physiol. 2019 Mar 1;316(3):G404-G411. doi: 10.1152/ajpgi.00188.2018. Epub 2019 Jan 17.

PMID:
30653340
15.

Ciprofloxacin penetration into infected hepatic cysts in autosomal dominant polycystic kidney disease: a case report.

Bernts LHP, Wallenburg E, de Jonge HJM, Schaap B, Kusters R, Overtoom TTC, Brüggemann RJM, Drenth JPH, Lantinga MA.

J Antimicrob Chemother. 2019 Mar 1;74(3):829-830. doi: 10.1093/jac/dky456. No abstract available.

PMID:
30452619
16.

Low skeletal muscle mass as a risk factor for postoperative delirium in elderly patients undergoing colorectal cancer surgery.

Mosk CA, van Vugt JLA, de Jonge H, Witjes CD, Buettner S, Ijzermans JN, van der Laan L.

Clin Interv Aging. 2018 Oct 24;13:2097-2106. doi: 10.2147/CIA.S175945. eCollection 2018.

17.

Generation and characterization of novel recombinant anti-hERG1 scFv antibodies for cancer molecular imaging.

Duranti C, Carraresi L, Sette A, Stefanini M, Lottini T, Crescioli S, Crociani O, Iamele L, De Jonge H, Gherardi E, Arcangeli A.

Oncotarget. 2018 Oct 9;9(79):34972-34989. doi: 10.18632/oncotarget.26200. eCollection 2018 Oct 9.

18.

IVACAFTOR restores FGF19 regulated bile acid homeostasis in cystic fibrosis patients with an S1251N or a G551D gating mutation.

van de Peppel IP, Doktorova M, Berkers G, de Jonge HR, Houwen RHJ, Verkade HJ, Jonker JW, Bodewes FAJA.

J Cyst Fibros. 2019 Mar;18(2):286-293. doi: 10.1016/j.jcf.2018.09.001. Epub 2018 Sep 29.

PMID:
30279125
19.

Relationship between In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Systemic Tacrolimus Metabolite/Parent Drug Ratio in Renal Transplant Recipients and Healthy Volunteers.

Vanhove T, de Jonge H, de Loor H, Oorts M, de Hoon J, Pohanka A, Annaert P, Kuypers DRJ.

Drug Metab Dispos. 2018 Nov;46(11):1507-1513. doi: 10.1124/dmd.118.081935. Epub 2018 Aug 30.

PMID:
30166405
20.

Stratifying infants with cystic fibrosis for disease severity using intestinal organoid swelling as a biomarker of CFTR function.

de Winter-de Groot KM, Janssens HM, van Uum RT, Dekkers JF, Berkers G, Vonk A, Kruisselbrink E, Oppelaar H, Vries R, Clevers H, Houwen RHJ, Escher JC, Elias SG, de Jonge HR, de Rijke YB, Tiddens HAWM, van der Ent CK, Beekman JM.

Eur Respir J. 2018 Sep 17;52(3). pii: 1702529. doi: 10.1183/13993003.02529-2017. Print 2018 Sep.

PMID:
30166324
21.

Adenylyl cyclase 6 is involved in the hyposecretory status of experimental colitis.

Romero-Calvo I, Ocón B, Gámez-Belmonte R, Hernández-Chirlaque C, de Jonge HR, Bijvelds MJ, Martínez-Augustin O, Sánchez de Medina F.

Pflugers Arch. 2018 Nov;470(11):1705-1717. doi: 10.1007/s00424-018-2187-z. Epub 2018 Aug 9.

PMID:
30094477
22.

Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers.

Yin J, Tse CM, Avula LR, Singh V, Foulke-Abel J, de Jonge HR, Donowitz M.

Cell Mol Gastroenterol Hepatol. 2018 Feb 9;5(4):591-609. doi: 10.1016/j.jcmgh.2018.02.002. eCollection 2018.

23.

Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors.

Bijvelds MJC, Tresadern G, Hellemans A, Smans K, Nieuwenhuijze NDA, Meijsen KF, Bongartz JP, Ver Donck L, de Jonge HR, Schuurkes JAJ, De Maeyer JH.

J Biol Chem. 2018 May 25;293(21):8173-8181. doi: 10.1074/jbc.RA118.002835. Epub 2018 Apr 13.

24.

Identification of a high affinity binding site for abscisic acid on human lanthionine synthetase component C-like protein 2.

Cichero E, Fresia C, Guida L, Booz V, Millo E, Scotti C, Iamele L, de Jonge H, Galante D, De Flora A, Sturla L, Vigliarolo T, Zocchi E, Fossa P.

Int J Biochem Cell Biol. 2018 Apr;97:52-61. doi: 10.1016/j.biocel.2018.02.003. Epub 2018 Feb 5.

PMID:
29421190
25.

Editorial overview: Respiratory: Transformational therapies for cystic fibrosis.

Sheppard DN, Bear CE, de Jonge HR.

Curr Opin Pharmacol. 2017 Jun;34:viii-xi. doi: 10.1016/j.coph.2017.11.006. No abstract available.

PMID:
29221574
26.

Cystic Fibrosis-related Liver Disease: Research Challenges and Future Perspectives.

Debray D, Narkewicz MR, Bodewes FAJA, Colombo C, Housset C, de Jonge HR, Jonker JW, Kelly DA, Ling SC, Poynard T, Sogni P, Trauner M, Witters P, Baumann U, Wilschanski M, Verkade HJ.

J Pediatr Gastroenterol Nutr. 2017 Oct;65(4):443-448. doi: 10.1097/MPG.0000000000001676.

PMID:
28753176
27.

SMARCA4 inactivating mutations cause concomitant Coffin-Siris syndrome, microphthalmia and small-cell carcinoma of the ovary hypercalcaemic type.

Errichiello E, Mustafa N, Vetro A, Notarangelo LD, de Jonge H, Rinaldi B, Vergani D, Giglio SR, Morbini P, Zuffardi O.

J Pathol. 2017 Sep;243(1):9-15. doi: 10.1002/path.4926. Epub 2017 Jul 25.

28.

Severe acute respiratory infection caused by swine influenza virus in a child necessitating extracorporeal membrane oxygenation (ECMO), the Netherlands, October 2016.

Fraaij PL, Wildschut ED, Houmes RJ, Swaan CM, Hoebe CJ, de Jonge HC, Tolsma P, de Kleer I, Pas SD, Oude Munnink BB, Phan MV, Bestebroer TM, Roosenhoff RS, van Kampen JJ, Cotten M, Beerens N, Fouchier RA, van den Kerkhof JH, Timen A, Koopmans MP.

Euro Surveill. 2016 Dec 1;21(48). pii: 30416. doi: 10.2807/1560-7917.ES.2016.21.48.30416.

29.

Comparative performance of oral midazolam clearance and plasma 4β-hydroxycholesterol to explain interindividual variability in tacrolimus clearance.

Vanhove T, de Jonge H, de Loor H, Annaert P, Diczfalusy U, Kuypers DR.

Br J Clin Pharmacol. 2016 Dec;82(6):1539-1549. doi: 10.1111/bcp.13083. Epub 2016 Sep 20.

30.

β2-Adrenergic receptor agonists activate CFTR in intestinal organoids and subjects with cystic fibrosis.

Vijftigschild LA, Berkers G, Dekkers JF, Zomer-van Ommen DD, Matthes E, Kruisselbrink E, Vonk A, Hensen CE, Heida-Michel S, Geerdink M, Janssens HM, van de Graaf EA, Bronsveld I, de Winter-de Groot KM, Majoor CJ, Heijerman HG, de Jonge HR, Hanrahan JW, van der Ent CK, Beekman JM.

Eur Respir J. 2016 Sep;48(3):768-79. doi: 10.1183/13993003.01661-2015. Epub 2016 Jul 28.

31.

Mycophenolic acid potently inhibits rotavirus infection with a high barrier to resistance development.

Yin Y, Wang Y, Dang W, Xu L, Su J, Zhou X, Wang W, Felczak K, van der Laan LJ, Pankiewicz KW, van der Eijk AA, Bijvelds M, Sprengers D, de Jonge H, Koopmans MP, Metselaar HJ, Peppelenbosch MP, Pan Q.

Antiviral Res. 2016 Sep;133:41-9. doi: 10.1016/j.antiviral.2016.07.017. Epub 2016 Jul 25.

PMID:
27468950
32.

Virological and Social Outcomes of HIV-Infected Adolescents and Young Adults in The Netherlands Before and After Transition to Adult Care.

Weijsenfeld AM, Smit C, Cohen S, Wit FWNM, Mutschelknauss M, van der Knaap LC, van Zonneveld LM, Zomer BJ, Nauta N, Patist JC, Kuipers-Jansen MHJ, Smit EP, Blokhuis C, Pajkrt D; Dutch HIV Adolescents and Young Adults (AYA) Study Group, Weijsenfeld AM, Cohen S, Blokhuis C, van der Plas A, Scherpbier HJ, Mutschelknauss M, Nellen FJB, Prins JM, Pajkrt D, Smit C, Wit FWNM, Reiss P, van der Knaap L, Visser E, van Zonneveld LM, Vriesde ME, Bassant NY, van der Ende ME, van Rossum AMC, Driessen GJA, Fraaij PLA, Smit JV, Smit EP, Kastelijns MPW, den Hollander JG, Pogány K, Moons C, Kroon FP, Oude Geerdink E, van der Meche IB, Schouten WEM, Brinkman K, Ter Beest G, Gisolf EH, Richter C, Zomer BJ, Strik-Albers R, van der Flier M, Henriet SS, Koopmans PP, Patist JC, Nauta N, Geelen SPM, Wolfs TFW, Hoepelman IM, Mudrikova T, van der Meulen PA, de Jonge H, Scholvink EH, Bierman WFW, van den Berg JF, Bouwhuis JW, Faber S, van Vonderen M, Schippers JA, Lowe SH, Kuipers-Jansen MHJ, van Kasteren MEE, Brouwer AE, Pronk DC, Kortmann W.

Clin Infect Dis. 2016 Oct 15;63(8):1105-1112. doi: 10.1093/cid/ciw487. Epub 2016 Jul 20.

PMID:
27439528
33.

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.

Dekkers JF, Berkers G, Kruisselbrink E, Vonk A, de Jonge HR, Janssens HM, Bronsveld I, van de Graaf EA, Nieuwenhuis EE, Houwen RH, Vleggaar FP, Escher JC, de Rijke YB, Majoor CJ, Heijerman HG, de Winter-de Groot KM, Clevers H, van der Ent CK, Beekman JM.

Sci Transl Med. 2016 Jun 22;8(344):344ra84. doi: 10.1126/scitranslmed.aad8278.

PMID:
27334259
34.

The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator.

van der Mark VA, de Jonge HR, Chang JC, Ho-Mok KS, Duijst S, Vidović D, Carlon MS, Oude Elferink RP, Paulusma CC.

Biochim Biophys Acta. 2016 Sep;1863(9):2280-8. doi: 10.1016/j.bbamcr.2016.06.005. Epub 2016 Jun 11.

35.

Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage.

Ikpa PT, Sleddens HF, Steinbrecher KA, Peppelenbosch MP, de Jonge HR, Smits R, Bijvelds MJ.

Histochem Cell Biol. 2016 Oct;146(4):445-55. doi: 10.1007/s00418-016-1453-4. Epub 2016 May 31.

36.

Potentiator synergy in rectal organoids carrying S1251N, G551D, or F508del CFTR mutations.

Dekkers JF, Van Mourik P, Vonk AM, Kruisselbrink E, Berkers G, de Winter-de Groot KM, Janssens HM, Bronsveld I, van der Ent CK, de Jonge HR, Beekman JM.

J Cyst Fibros. 2016 Sep;15(5):568-78. doi: 10.1016/j.jcf.2016.04.007. Epub 2016 May 5.

37.

Continuous 'Passive' flow-proportional monitoring of drainage using a new modified Sutro weir (MSW) unit.

Vendelboe AL, Rozemeijer J, de Jonge LW, de Jonge H.

Environ Monit Assess. 2016 Mar;188(3):190. doi: 10.1007/s10661-016-5188-4. Epub 2016 Feb 25.

PMID:
26914326
38.

Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology.

Foulke-Abel J, In J, Yin J, Zachos NC, Kovbasnjuk O, Estes MK, de Jonge H, Donowitz M.

Gastroenterology. 2016 Mar;150(3):638-649.e8. doi: 10.1053/j.gastro.2015.11.047. Epub 2015 Dec 8.

39.

Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology.

Zachos NC, Kovbasnjuk O, Foulke-Abel J, In J, Blutt SE, de Jonge HR, Estes MK, Donowitz M.

J Biol Chem. 2016 Feb 19;291(8):3759-66. doi: 10.1074/jbc.R114.635995. Epub 2015 Dec 16. Review.

40.

Value of Organoids from Comparative Epithelia Models.

Schwarz JS, de Jonge HR, Forrest JN Jr.

Yale J Biol Med. 2015 Nov 24;88(4):367-74. eCollection 2015 Dec. Review.

41.

rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice.

Vidović D, Carlon MS, da Cunha MF, Dekkers JF, Hollenhorst MI, Bijvelds MJ, Ramalho AS, Van den Haute C, Ferrante M, Baekelandt V, Janssens HM, De Boeck K, Sermet-Gaudelus I, de Jonge HR, Gijsbers R, Beekman JM, Edelman A, Debyser Z.

Am J Respir Crit Care Med. 2016 Feb 1;193(3):288-98. doi: 10.1164/rccm.201505-0914OC.

PMID:
26509335
42.

Modeling rotavirus infection and antiviral therapy using primary intestinal organoids.

Yin Y, Bijvelds M, Dang W, Xu L, van der Eijk AA, Knipping K, Tuysuz N, Dekkers JF, Wang Y, de Jonge J, Sprengers D, van der Laan LJ, Beekman JM, Ten Berge D, Metselaar HJ, de Jonge H, Koopmans MP, Peppelenbosch MP, Pan Q.

Antiviral Res. 2015 Nov;123:120-31. doi: 10.1016/j.antiviral.2015.09.010. Epub 2015 Sep 25.

PMID:
26408355
43.

Response to 'Tacrolimus pharmacokinetics after kidney transplantation--Influence of changes in haematocrit and steroid dose'.

Vanhove T, de Jonge H, de Loor H, Verbeke K, Kuypers DR.

Br J Clin Pharmacol. 2015 Dec;80(6):1473-4. doi: 10.1111/bcp.12728. Epub 2015 Sep 15. No abstract available.

44.

Progressive decline in tacrolimus clearance after renal transplantation is partially explained by decreasing CYP3A4 activity and increasing haematocrit.

de Jonge H, Vanhove T, de Loor H, Verbeke K, Kuypers DR.

Br J Clin Pharmacol. 2015 Sep;80(3):548-59. doi: 10.1111/bcp.12703. Epub 2015 Aug 3.

45.

ANP and CNP activate CFTR expressed in Xenopus laevis oocytes by direct activation of PKA.

Stahl K, Stahl M, de Jonge HR, Forrest JN Jr.

J Recept Signal Transduct Res. 2015;35(5):493-504. doi: 10.3109/10799893.2015.1015738. Epub 2015 May 27.

PMID:
26016495
46.

Inhibition of Heat-Stable Toxin-Induced Intestinal Salt and Water Secretion by a Novel Class of Guanylyl Cyclase C Inhibitors.

Bijvelds MJ, Loos M, Bronsveld I, Hellemans A, Bongartz JP, Ver Donck L, Cox E, de Jonge HR, Schuurkes JA, De Maeyer JH.

J Infect Dis. 2015 Dec 1;212(11):1806-15. doi: 10.1093/infdis/jiv300. Epub 2015 May 21.

PMID:
25999056
47.

Rhodococcus equi Sepsis in a Renal Transplant Recipient: A Case Study.

Macken E, de Jonge H, Van Caesbroeck D, Verhaegen J, Van Kerkhoven D, Van Wijngaerden E, Kuypers D.

Transplant Direct. 2015 Apr 1;1(3):e11. doi: 10.1097/TXD.0000000000000519. eCollection 2015 Apr.

48.

Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea.

Moon C, Zhang W, Ren A, Arora K, Sinha C, Yarlagadda S, Woodrooffe K, Schuetz JD, Valasani KR, de Jonge HR, Shanmukhappa SK, Shata MT, Buddington RK, Parthasarathi K, Naren AP.

J Biol Chem. 2015 May 1;290(18):11246-57. doi: 10.1074/jbc.M114.605410. Epub 2015 Mar 11.

49.

Semi-synthesis of a HGF/SF kringle one (K1) domain scaffold generates a potent in vivo MET receptor agonist.

Simonneau C, Bérénice Leclercq, Mougel A, Adriaenssens E, Paquet C, Raibaut L, Ollivier N, Drobecq H, Marcoux J, Cianférani S, Tulasne D, de Jonge H, Melnyk O, Vicogne J.

Chem Sci. 2015 Mar 1;6(3):2110-2121. doi: 10.1039/c4sc03856h. Epub 2015 Jan 29.

50.

Cholic acid induces a Cftr dependent biliary secretion and liver growth response in mice.

Bodewes FA, Bijvelds MJ, de Vries W, Baller JF, Gouw AS, de Jonge HR, Verkade HJ.

PLoS One. 2015 Feb 13;10(2):e0117599. doi: 10.1371/journal.pone.0117599. eCollection 2015.

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