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Items: 37

1.

Unraveling the Macromolecular Pathways of IgG Oligomerization and Complement Activation on Antigenic Surfaces.

Strasser J, de Jong RN, Beurskens FJ, Wang G, Heck AJR, Schuurman J, Parren PWHI, Hinterdorfer P, Preiner J.

Nano Lett. 2019 Jul 10;19(7):4787-4796. doi: 10.1021/acs.nanolett.9b02220. Epub 2019 Jun 11.

PMID:
31184907
2.

CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering.

Oostindie SC, van der Horst HJ, Lindorfer MA, Cook EM, Tupitza JC, Zent CS, Burack R, VanDerMeid KR, Strumane K, Chamuleau MED, Mutis T, de Jong RN, Schuurman J, Breij ECW, Beurskens FJ, Parren PWHI, Taylor RP.

Haematologica. 2019 Feb 21. pii: haematol.2018.207266. doi: 10.3324/haematol.2018.207266. [Epub ahead of print]

3.

Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement.

Ugurlar D, Howes SC, de Kreuk BJ, Koning RI, de Jong RN, Beurskens FJ, Schuurman J, Koster AJ, Sharp TH, Parren PWHI, Gros P.

Science. 2018 Feb 16;359(6377):794-797. doi: 10.1126/science.aao4988.

PMID:
29449492
4.

Kinetic mechanism of controlled Fab-arm exchange for the formation of bispecific immunoglobulin G1 antibodies.

Goulet DR, Orcutt SJ, Zwolak A, Rispens T, Labrijn AF, de Jong RN, Atkins WM, Chiu ML.

J Biol Chem. 2018 Jan 12;293(2):651-661. doi: 10.1074/jbc.RA117.000303. Epub 2017 Nov 17.

5.

Cysteine-SILAC Mass Spectrometry Enabling the Identification and Quantitation of Scrambled Interchain Disulfide Bonds: Preservation of Native Heavy-Light Chain Pairing in Bispecific IgGs Generated by Controlled Fab-arm Exchange.

van den Bremer ETJ, Labrijn AF, van den Boogaard R, Priem P, Scheffler K, Melis JPM, Schuurman J, Parren PWHI, de Jong RN.

Anal Chem. 2017 Oct 17;89(20):10873-10882. doi: 10.1021/acs.analchem.7b02543. Epub 2017 Oct 2.

PMID:
28922593
6.

Enhancing Accuracy in Molecular Weight Determination of Highly Heterogeneously Glycosylated Proteins by Native Tandem Mass Spectrometry.

Wang G, de Jong RN, van den Bremer ETJ, Parren PWHI, Heck AJR.

Anal Chem. 2017 May 2;89(9):4793-4797. doi: 10.1021/acs.analchem.6b05129. Epub 2017 Apr 13.

7.

Molecular Basis of Assembly and Activation of Complement Component C1 in Complex with Immunoglobulin G1 and Antigen.

Wang G, de Jong RN, van den Bremer ET, Beurskens FJ, Labrijn AF, Ugurlar D, Gros P, Schuurman J, Parren PW, Heck AJ.

Mol Cell. 2016 Jul 7;63(1):135-45. doi: 10.1016/j.molcel.2016.05.016. Epub 2016 Jun 16.

8.

A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface.

de Jong RN, Beurskens FJ, Verploegen S, Strumane K, van Kampen MD, Voorhorst M, Horstman W, Engelberts PJ, Oostindie SC, Wang G, Heck AJ, Schuurman J, Parren PW.

PLoS Biol. 2016 Jan 6;14(1):e1002344. doi: 10.1371/journal.pbio.1002344. eCollection 2016 Jan.

9.

Real-time analysis of the detailed sequence of cellular events in mAb-mediated complement-dependent cytotoxicity of B-cell lines and of chronic lymphocytic leukemia B-cells.

Lindorfer MA, Cook EM, Tupitza JC, Zent CS, Burack R, de Jong RN, Beurskens FJ, Schuurman J, Parren PW, Taylor RP.

Mol Immunol. 2016 Feb;70:13-23. doi: 10.1016/j.molimm.2015.12.007. Epub 2015 Dec 12.

PMID:
26690706
10.

Human IgG is produced in a pro-form that requires clipping of C-terminal lysines for maximal complement activation.

van den Bremer ET, Beurskens FJ, Voorhorst M, Engelberts PJ, de Jong RN, van der Boom BG, Cook EM, Lindorfer MA, Taylor RP, van Berkel PH, Parren PW.

MAbs. 2015;7(4):672-80. doi: 10.1080/19420862.2015.1046665.

11.

Tandem Native Mass-Spectrometry on Antibody-Drug Conjugates and Submillion Da Antibody-Antigen Protein Assemblies on an Orbitrap EMR Equipped with a High-Mass Quadrupole Mass Selector.

Dyachenko A, Wang G, Belov M, Makarov A, de Jong RN, van den Bremer ET, Parren PW, Heck AJ.

Anal Chem. 2015 Jun 16;87(12):6095-102. doi: 10.1021/acs.analchem.5b00788. Epub 2015 May 27.

PMID:
25978613
12.

Functional analysis of the anti-adalimumab response using patient-derived monoclonal antibodies.

van Schouwenburg PA, Kruithof S, Votsmeier C, van Schie K, Hart MH, de Jong RN, van Buren EE, van Ham M, Aarden L, Wolbink G, Wouters D, Rispens T.

J Biol Chem. 2014 Dec 12;289(50):34482-8. doi: 10.1074/jbc.M114.615500. Epub 2014 Oct 17. Review.

13.

Controlled Fab-arm exchange for the generation of stable bispecific IgG1.

Labrijn AF, Meesters JI, Priem P, de Jong RN, van den Bremer ET, van Kampen MD, Gerritsen AF, Schuurman J, Parren PW.

Nat Protoc. 2014 Oct;9(10):2450-63. doi: 10.1038/nprot.2014.169. Epub 2014 Sep 25.

PMID:
25255089
14.

Complement is activated by IgG hexamers assembled at the cell surface.

Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJ, van de Winkel JG, Wilson IA, Koster AJ, Taylor RP, Saphire EO, Burton DR, Schuurman J, Gros P, Parren PW.

Science. 2014 Mar 14;343(6176):1260-3. doi: 10.1126/science.1248943.

15.

A simple, robust and highly efficient transient expression system for producing antibodies.

Vink T, Oudshoorn-Dickmann M, Roza M, Reitsma JJ, de Jong RN.

Methods. 2014 Jan 1;65(1):5-10. doi: 10.1016/j.ymeth.2013.07.018. Epub 2013 Jul 17.

16.

Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation.

van Schouwenburg PA, van de Stadt LA, de Jong RN, van Buren EE, Kruithof S, de Groot E, Hart M, van Ham SM, Rispens T, Aarden L, Wolbink GJ, Wouters D.

Ann Rheum Dis. 2013 Jan;72(1):104-9. doi: 10.1136/annrheumdis-2012-201445. Epub 2012 Jul 3.

PMID:
22759910
17.

Symmetry and asymmetry of the RING-RING dimer of Rad18.

Huang A, Hibbert RG, de Jong RN, Das D, Sixma TK, Boelens R.

J Mol Biol. 2011 Jul 15;410(3):424-35. doi: 10.1016/j.jmb.2011.04.051. Epub 2011 Apr 27.

PMID:
21549715
18.

NMR characterization of foldedness for the production of E3 RING domains.

Huang A, de Jong RN, Folkers GE, Boelens R.

J Struct Biol. 2010 Oct;172(1):120-7. doi: 10.1016/j.jsb.2010.07.014. Epub 2010 Aug 2.

PMID:
20682345
19.

E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity.

Huang A, de Jong RN, Wienk H, Winkler GS, Timmers HT, Boelens R.

J Mol Biol. 2009 Jan 16;385(2):507-19. doi: 10.1016/j.jmb.2008.10.044. Epub 2008 Nov 1.

PMID:
18996392
20.

Solution structure and characterization of the DNA-binding activity of the B3BP-Smr domain.

Diercks T, AB E, Daniels MA, de Jong RN, Besseling R, Kaptein R, Folkers GE.

J Mol Biol. 2008 Nov 28;383(5):1156-70. doi: 10.1016/j.jmb.2008.09.005. Epub 2008 Sep 12.

PMID:
18804481
21.

Structure and DNA binding of the human Rtf1 Plus3 domain.

de Jong RN, Truffault V, Diercks T, Ab E, Daniels MA, Kaptein R, Folkers GE.

Structure. 2008 Jan;16(1):149-59. doi: 10.1016/j.str.2007.10.018.

22.

Enzyme free cloning for high throughput gene cloning and expression.

de Jong RN, Daniëls MA, Kaptein R, Folkers GE.

J Struct Funct Genomics. 2006 Dec;7(3-4):109-18. Epub 2007 Feb 13.

PMID:
17295099
23.

First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value.

Banci L, Bertini I, Cusack S, de Jong RN, Heinemann U, Jones EY, Kozielski F, Maskos K, Messerschmidt A, Owens R, Perrakis A, Poterszman A, Schneider G, Siebold C, Silman I, Sixma T, Stewart-Jones G, Sussman JL, Thierry JC, Moras D.

Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1208-17. Epub 2006 Sep 19. Review.

PMID:
17001097
24.

NMR in the SPINE Structural Proteomics project.

Ab E, Atkinson AR, Banci L, Bertini I, Ciofi-Baffoni S, Brunner K, Diercks T, Dötsch V, Engelke F, Folkers GE, Griesinger C, Gronwald W, Günther U, Habeck M, de Jong RN, Kalbitzer HR, Kieffer B, Leeflang BR, Loss S, Luchinat C, Marquardsen T, Moskau D, Neidig KP, Nilges M, Piccioli M, Pierattelli R, Rieping W, Schippmann T, Schwalbe H, Travé G, Trenner J, Wöhnert J, Zweckstetter M, Kaptein R.

Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1150-61. Epub 2006 Sep 19. Review.

PMID:
17001092
25.

Structural characterization of Spo0E-like protein-aspartic acid phosphatases that regulate sporulation in bacilli.

Grenha R, Rzechorzek NJ, Brannigan JA, de Jong RN, Ab E, Diercks T, Truffault V, Ladds JC, Fogg MJ, Bongiorni C, Perego M, Kaptein R, Wilson KS, Folkers GE, Wilkinson AJ.

J Biol Chem. 2006 Dec 8;281(49):37993-8003. Epub 2006 Sep 25.

26.

Relaxed template specificity in fowl adenovirus 1 DNA replication initiation.

Rademaker HJ, Fallaux FJ, Van den Wollenberg DJ, De Jong RN, Van der Vliet PC, Hoeben RC.

J Gen Virol. 2006 Mar;87(Pt 3):553-62.

PMID:
16476976
27.

Solution structure of the human ubiquitin-specific protease 15 DUSP domain.

de Jong RN, Ab E, Diercks T, Truffault V, Daniëls M, Kaptein R, Folkers GE.

J Biol Chem. 2006 Feb 24;281(8):5026-31. Epub 2005 Nov 18.

28.

The structure of bypass of forespore C, an intercompartmental signaling factor during sporulation in Bacillus.

Patterson HM, Brannigan JA, Cutting SM, Wilson KS, Wilkinson AJ, Ab E, Diercks T, de Jong RN, Truffault V, Folkers GE, Kaptein R.

J Biol Chem. 2005 Oct 28;280(43):36214-20. Epub 2005 Jul 27.

29.

DNA binding properties of the adenovirus DNA replication priming protein pTP.

de Jong RN, Meijer LA, van der Vliet PC.

Nucleic Acids Res. 2003 Jun 15;31(12):3274-86.

30.

Adenovirus DNA replication: protein priming, jumping back and the role of the DNA binding protein DBP.

de Jong RN, van der Vliet PC, Brenkman AB.

Curr Top Microbiol Immunol. 2003;272:187-211. Review.

PMID:
12747551
31.

Recruitment of the priming protein pTP and DNA binding occur by overlapping Oct-1 POU homeodomain surfaces.

de Jong RN, Mysiak ME, Meijer LA, van der Linden M, van der Vliet PC.

EMBO J. 2002 Feb 15;21(4):725-35.

32.

A direct interaction between proliferating cell nuclear antigen (PCNA) and Cdk2 targets PCNA-interacting proteins for phosphorylation.

Koundrioukoff S, Jónsson ZO, Hasan S, de Jong RN, van der Vliet PC, Hottiger MO, Hübscher U.

J Biol Chem. 2000 Jul 28;275(30):22882-7.

33.
34.

Use of Women's Health Care Specialists in a women's clinic.

De Jong RN Jr.

J Reprod Med. 1981 Jun;26(6):283-8.

PMID:
6114175
35.

Creutzfeldt-Jakob disease. II. Clinical, pathologic, and genetic study of a family.

May WW, Itabashi HH, De Jong RN.

Arch Neurol. 1968 Aug;19(2):137-49. No abstract available.

PMID:
5675300
36.

The treatment of vascular headaches.

DE JONG RN.

GP. 1959 Apr;19(4):147-54. No abstract available.

PMID:
13640120
37.

Further observations on the use of tridione in the control of psychomotor attacks.

DE JONG RN.

Am J Psychiatry. 1946 Sep;103(2):162-4. No abstract available.

PMID:
21001985

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